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[192952_at] G-protein coupled receptor

Description F56B6.5 /REP_DB=WormBase Gene ID /WP=CE04665 /GEN=uvt-6 /TR=Q22995 /GB=AAB04560.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster 6grp_total > 16      4grp_total > 30      6grp_cgc > 13      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 311
1 2 3 4 range
A 515.8
(3)
A 		220.5
(-2.7)
A 		204.9
(-3)
A 		433.4
(1.4)
A 		311
B 374.2
(3)
A 		305.8
(0.5)
A 		208.6
(-3)
A 		333.8
(1.5)
A 		166
C 482
(3)
A 		324.6
(-1.3)
A 		261.7
(-3)
A 		405.3
(0.9)
A 		220
avr 457.3
(3) 		283.6
(-1.5) 		225.1
(-3) 		390.8
(1.3) 		232

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 384
1 2 3 4 5 6 range
A 405.6
(3)
A 		317.1
(0.4)
A 		265.6
(-1.1)
A 		234.7
(-2)
A 		199.4
(-3)
A 		239.3
(-1.8)
A 		206
B 573.3
(3)
A 		402.4
(0.3)
A 		235
(-2.3)
A 		206.5
(-2.7)
A 		278.3
(-1.6)
A 		190.1
(-3)
A 		383
C 399.5
(3)
A 		393.1
(2.8)
A 		189.6
(-3)
A 		258.1
(-1)
A 		235.8
(-1.7)
A 		198.4
(-2.7)
A 		210
avr 459.5
(3) 		370.9
(0.9) 		230.1
(-2.5) 		233.1
(-2.4) 		237.8
(-2.3) 		209.3
(-3) 		250
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 140
1 2 3 4 range
A 187.8
(3)
A 		47.9
(-3)
A 		53.6
(-2.8)
A 		63.4
(-2.3)
A 		140
B 119.3
(3)
A 		75.5
(-0.7)
A 		48.3
(-3)
A 		71.1
(-1.1)
A 		71
C 159.6
(3)
A 		93.3
(-1.4)
A 		91.2
(-1.5)
A 		68.3
(-3)
A 		91
avr 155.6
(3) 		72.2
(-2.5) 		64.4
(-3) 		67.6
(-2.8) 		91

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 151
1 2 3 4 5 6 range
A 74.8
(-1.2)
A 		112.8
(3)
A 		57.9
(-3)
A 		59.5
(-2.8)
A 		60.2
(-2.7)
A 		58.3
(-3)
A 		55
B 199.5
(3)
A 		133.9
(0.3)
A 		57.1
(-2.9)
A 		54.7
(-3)
A 		113.1
(-0.6)
A 		70.9
(-2.3)
A 		145
C 148.1
(3)
A 		119.9
(1.3)
A 		48.3
(-3)
A 		51.9
(-2.8)
A 		76.3
(-1.3)
A 		66.4
(-1.9)
A 		100
avr 140.8
(3) 		122.2
(1.7) 		54.4
(-3) 		55.4
(-2.9) 		83.2
(-1) 		65.2
(-2.3) 		86
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192952_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18256
Sequence Type Exemplar sequence
Representative Public ID F56B6.5 NCBI
Target Description F56B6.5 /REP_DB=WormBase Gene ID /WP=CE04665 /GEN=uvt-6 /TR=Q22995 /GB=AAB04560.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076205(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076205 NCBI Caenorhabditis elegans Unidentified Vitellogenin-linked Transcript family member (uvt-6) (uvt-6) mRNA, complete cds. 10/11 A 
GENEFINDER00000023814 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:3528805:3531683:1 11/11 None
F56B6.5 ENSEMBL cdna:known chromosome:CEL140:X:3528799:3531813:1 gene:F56B6.5 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000023801 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:3527918-3531174(+) 100.0 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor
Gene Symbol uvt-6
Ensembl F56B6.5
Entrez Gene 180643 Entrez gene
SwissProt Q22995 EMBL-EBI
WormBase CE31186 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.3154.1.S1_AT somatostatin receptor 3 cfa
CHICKEN:GGAAFFX.23919.1.S1_AT somatostatin receptor 3 gga
CHICKEN:GGA.19891.1.S1_AT Somatostatin receptor 3 gga
HG-U133_PLUS_2:214491_AT somatostatin receptor 3 hs
HG-U133A_2:214491_AT somatostatin receptor 3 hs
HG-FOCUS:214491_AT somatostatin receptor 3 hs
HG-U133A:214491_AT somatostatin receptor 3 hs
HG-U95AV2:557_S_AT somatostatin receptor 3 hs
HC-G110:557_S_AT somatostatin receptor 3 hs
HUGENEFL:Z86000_AT somatostatin receptor 3 hs
HUGENEFL:M96738_S_AT somatostatin receptor 3 hs
U133_X3P:HS2.225995.1.S1_3P_S_AT somatostatin receptor 3 hs
U133_X3P:HS.225995.0.S1_3P_AT somatostatin receptor 3 hs
HG-U133_PLUS_2:1553178_A_AT somatostatin receptor 3 hs
MOE430A:1450577_AT somatostatin receptor 3 mm
MOUSE430_2:1450577_AT somatostatin receptor 3 mm
MOUSE430A_2:1450577_AT somatostatin receptor 3 mm
MU11KSUBB:MSA.1187.0_AT somatostatin receptor 3 mm
MG-U74AV2:101309_AT somatostatin receptor 3 mm
MOE430B:1441603_AT Somatostatin receptor 3 (Sstr3), mRNA mm
MOUSE430_2:1441603_AT Somatostatin receptor 3 (Sstr3), mRNA mm
RAE230A:1368598_AT hypothetical gene supported by NM_133522 rn
RAT230_2:1368598_AT hypothetical gene supported by NM_133522 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB04560 Unidentified vitellogenin-linked transcript protein 6 [Caenorhabditis elegans] ref|NP_508606.2| Unidentified Vitellogenin-linked Transcript family member (uvt-6) [Caenorhabditis elegans] 0.0
blast CAE68442 Hypothetical protein CBG14230 [Caenorhabditis briggsae] 0.0
blast EAA03588 ENSANGP00000018071 [Anopheles gambiae str. PEST] ref|XP_307800.2| ENSANGP00000018071 [Anopheles gambiae str. PEST] 2.0E-32
blast AAF98367 somatostatin receptor type two [Carassius auratus] 4.0E-32
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 1.7E-50
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508606.2 7 10-32,45-67,82-104,125-147,182-204,240-262,272-294
F56B6.5 7 10-32,45-67,82-104,125-147,182-204,240-262,272-294
GENEFINDER00000023814 7 10-32,45-67,82-104,125-147,182-204,240-262,272-294
Sequence
Target Sequence 
>C. ELEGANS:192952_AT
gtattgctcattggccaagtccaccacacgcacagtggtatatctctgtgtgctcggtga
tgatcttcatacttccgggacttgtgattttctactgctattatcatgtattttgtaaat
tacgagaagctgcaaagggttctaggagattgcatcgtaataagagatcaaggtcttcat
atcaaagagtcactcgaagtgtacaacgggttgtattgtttcatttactttgttggtccc
cattctggttgttcaatttgttttctgccatcttccgggttcgaataacaacacaattaa
tgagaatcatagtcaacatcattcacctcttcccttatgtgaactgtgcacttaatccag
tattatatgcataccgagcagaaaacttccggaccgcattcaaatcactgctcttctgga
gccgacgcttggactgtttgaaatcctcgttgcccataaagtcaacaatggagccagcat
ccgtgtacc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTATTGCTCATTGGCCAAGTCCACC 606 451 440 Antisense
GTATATCTCTGTGTGCTCGGTGATG 579 453 477 Antisense
GATCTTCATACTTCCGGGACTTGTG 222 419 501 Antisense
GGGACTTGTGATTTTCTACTGCTAT 328 495 516 Antisense
GTTCAATTTGTTTTCTGCCATCTTC 631 445 690 Antisense
TCATAGTCAACATCATTCACCTCTT 90 621 746 Antisense
CACCTCTTCCCTTATGTGAACTGTG 588 201 763 Antisense
TCCGGACCGCATTCAAATCACTGCT 272 593 827 Antisense
AGCCGACGCTTGGACTGTTTGAAAT 78 83 859 Antisense
TGAAATCCTCGTTGCCCATAAAGTC 696 571 878 Antisense
ACAATGGAGCCAGCATCCGTGTACC 691 111 904 Antisense
Sequence Source Affymetrix Proprietary Database