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[192934_s_at] proteasome A-type submit

Description C36B1.4 /REP_DB=WormBase Gene ID /WP=CE05371 /GEN=pas-4 /TR=SW:Q95005 /GB=CAB02269.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=proteasome A-type submit
Cluster 6grp_highest_10_10 > 37      6grp_high1_10_10 > 73      4grp_highest_8_8 > 10      4grp_high_8_8 > 55      6grp_highest_nonorm > 57      6grp_total > 64      4grp_total > 57      6grp_highest_sub > 03_04      6grp_cgc > 93      6grp_high1_sub > 03_04      6grp_cgc_sub > 03      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2169
1 2 3 4 range
A 2119.9
(-3)
P 		3601.4
(2.5)
P 		3731.6
(3)
P 		2176.9
(-2.8)
P 		1612
B 2342.8
(-2.7)
P 		3445.6
(0.5)
P 		4289.2
(3)
P 		2251.5
(-3)
P 		2038
C 2256.1
(-3)
P 		3123.1
(1.7)
P 		3371.3
(3)
P 		2365.4
(-2.4)
P 		1115
avr 2239.6
(-3) 		3390
(1.4) 		3797.4
(3) 		2264.6
(-2.9) 		1558

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1275
1 2 3 4 5 6 range
A 2710
(3)
P 		2042.3
(-3)
P 		2566.1
(1.7)
P 		2365
(-0.1)
P 		2318.6
(-0.5)
P 		2251.6
(-1.1)
P 		668
B 2293
(-2.8)
P 		2266.6
(-3)
P 		3317.2
(3)
P 		2893.6
(0.6)
P 		2388.7
(-2.3)
P 		2503.9
(-1.6)
P 		1051
C 2054.2
(-3)
P 		2310.4
(-1.2)
P 		2475.3
(0)
P 		2892.3
(3)
P 		2081.8
(-2.8)
P 		2742.3
(1.9)
P 		838
avr 2352.4
(-1.5) 		2206.4
(-3) 		2786.2
(3) 		2717
(2.3) 		2263
(-2.4) 		2499.3
(0) 		580
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 856
1 2 3 4 range
A 771.8
(1.1)
P 		781.8
(1.2)
P 		975.5
(3)
P 		318.7
(-3)
P 		657
B 747.1
(0.1)
P 		851
(1.3)
P 		993.9
(3)
P 		479.8
(-3)
P 		514
C 746.8
(-0.3)
P 		897.9
(0.9)
P 		1175
(3)
P 		398.8
(-3)
P 		776
avr 755.2
(0.3) 		843.6
(1.1) 		1048.1
(3) 		399.1
(-3) 		649

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 471
1 2 3 4 5 6 range
A 499.6
(-3)
P 		726.4
(3)
P 		558.9
(-1.4)
P 		599.8
(-0.3)
P 		699.7
(2.3)
P 		548.2
(-1.7)
P 		227
B 797.9
(-1.8)
P 		754.5
(-3)
P 		805.5
(-1.6)
P 		766.4
(-2.7)
P 		970.5
(3)
P 		933.7
(2)
P 		216
C 761.4
(0.2)
P 		705
(-0.8)
P 		630
(-2.1)
P 		581.7
(-3)
P 		673.6
(-1.4)
P 		918
(3)
P 		336
avr 686.3
(-1.5) 		728.6
(0.2) 		664.8
(-2.4) 		649.3
(-3) 		781.3
(2.3) 		800
(3) 		151
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192934_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1617
Sequence Type Exemplar sequence
Representative Public ID C36B1.4 NCBI
Target Description C36B1.4 /REP_DB=WormBase Gene ID /WP=CE05371 /GEN=pas-4 /TR=SW:Q95005 /GB=CAB02269.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=proteasome A-type submit
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059959(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059959 NCBI Caenorhabditis elegans Proteasome Alpha Subunit family member (pas-4) (pas-4) mRNA, complete cds. 11/11 None
SNAP00000022501 ENSEMBL cdna:SNAP chromosome:CEL140:I:8735464:8738588:-1 11/11 None
GENEFINDER00000022509 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:8735464:8736612:-1 11/11 None
C36B1.4.3 ENSEMBL cdna:known chromosome:CEL140:I:8735246:8736612:-1 gene:C36B1.4 11/11 None
C36B1.4.1 ENSEMBL cdna:known chromosome:CEL140:I:8735343:8736622:-1 gene:C36B1.4 11/11 None
C36B1.4.2 ENSEMBL cdna:known chromosome:CEL140:I:8735343:8736612:-1 gene:C36B1.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8735394-8736543(-) 100.0 100.0
Public Domain and Genome References
Gene Title proteasome A-type submit
Gene Symbol pas-4
Ensembl C36B1.4
Entrez Gene 172679 Entrez gene
SwissProt Q95005 EMBL-EBI
WormBase CE05371 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:247080_AT 20S proteasome alpha subunit D2 (PAD2) (PRS1) (PRC6) at
CANINE:1602360_AT proteasome (prosome, macropain) subunit, alpha type, 7 cfa
CANINE_2:CFAAFFX.18873.1.S1_S_AT proteasome (prosome, macropain) subunit, alpha type, 7 cfa
CHICKEN:GGA.2045.2.S1_A_AT proteasome (prosome, macropain) subunit, alpha type, 7 gga
HG-U133_PLUS_2:201114_X_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HG-U133A:201114_X_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HG-U133A_2:201114_X_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HG-U133_PLUS_2:216088_S_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HG-U133A_2:216088_S_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HG-FOCUS:216088_S_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HG-U133A:216088_S_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HU35KSUBA:AA313677_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
U133_X3P:HS.233952.3.S1_3P_A_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HG-U95AV2:33449_AT proteasome (prosome, macropain) subunit, alpha type, 7 hs
HU35KSUBC:RC_N57710_AT Proteasome (prosome, macropain) subunit, alpha type, 7 hs
HG-U95B:47026_AT Proteasome (prosome, macropain) subunit, alpha type, 7 hs
MU11KSUBA:AA592029_S_AT proteasome (prosome, macropain) subunit, alpha type 7 mm
MG-U74AV2:93988_AT proteasome (prosome, macropain) subunit, alpha type 7 mm
MOE430A:1423568_AT proteasome (prosome, macropain) subunit, alpha type 7 mm
MOUSE430A_2:1423568_AT proteasome (prosome, macropain) subunit, alpha type 7 mm
MOUSE430_2:1423568_AT proteasome (prosome, macropain) subunit, alpha type 7 mm
MOE430A:1423567_A_AT proteasome (prosome, macropain) subunit, alpha type 7 mm
MOUSE430A_2:1423567_A_AT proteasome (prosome, macropain) subunit, alpha type 7 mm
MOUSE430_2:1423567_A_AT proteasome (prosome, macropain) subunit, alpha type 7 mm
MU19KSUBA:TC24584_S_AT Proteasome (prosome, macropain) subunit, alpha type 7, mRNA (cDNA clone MGC:6440 IMAGE:2581897) mm
RG-U34A:D30804_G_AT proteasome (prosome, macropain) subunit, alpha type 7 rn
RG-U34A:D30804_AT proteasome (prosome, macropain) subunit, alpha type 7 rn
RG-U34B:RC_AA925475_AT proteasome (prosome, macropain) subunit, alpha type 7 rn
RG-U34C:RC_AI179950_S_AT proteasome (prosome, macropain) subunit, alpha type 7 rn
RAE230A:1371869_AT proteasome (prosome, macropain) subunit, alpha type 7 rn
RAT230_2:1371869_AT proteasome (prosome, macropain) subunit, alpha type 7 rn
RG-U34C:RC_AI072328_AT Proteasome (prosome, macropain) subunit, alpha type 7 rn
YEAST_2:1773650_AT 20S proteasome alpha-type subunit Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6511 ubiquitin-dependent protein catabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5839 proteasome core complex (sensu Eukaryota) inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4175 endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02269 Hypothetical protein C36B1.4 [Caenorhabditis elegans] ref|NP_492360.1| Proteasome Alpha Subunit family member (pas-4) [Caenorhabditis elegans] sp|Q95005|PSA7_CAEEL Proteasome subunit alpha type 7 (Proteasome subunit alpha 4) 1.0E-130
blast CAE66957 Hypothetical protein CBG12349 [Caenorhabditis briggsae] 1.0E-127
Protein Domains
Database ID Description E-Value
Pfam IPR001353 EMBL-EBI Peptidase T1, 20S proteasome 2.2E-72
Pfam IPR001353 EMBL-EBI Peptidase T1, 20S proteasome 2.2E-72
Sequence
Target Sequence 
>C. ELEGANS:192934_S_AT
ttccagctcttcaagatgaccgcacaatccgtaaaattcatatgatcgacgaccatgtga
tgctcgcttttgctggattgtccgcagatgctcgtgttcttgttgatcgtgctcgtatcg
agtgccagtcgtacaagttgactcttgaagatccagttaccgttgcctatatctccagat
atattgcaaacacgaagcagcgcttcacacaatctccaggacgtcgcccattcggaattt
caatgctcattggaggattcgatcatgacggaactccacgtcttttcaaaaccgagccat
ctggagcttactacgagtacgttgccaacgcgactggaagaggagagaaaccagtgcgtg
aataccttgaggagcaatacagcgaggaaaatactgtcgacgaagctaccactcttaaat
tggttgtaaagtcgctggctcaggtcgtaccaccaggatcacaaaatatcgagattgcag
tcatgaaaaaagttaatgatgagctgcagcaacgtgtattgtcaactgaagaaatcgagg
ctctcctgaaggttgtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCCAGCTCTTCAAGATGACCGCAC 295 693 164 Antisense
GATCGACGACCATGTGATGCTCGCT 649 417 207 Antisense
TGATGCTCGCTTTTGCTGGATTGTC 311 565 221 Antisense
ATGCTCGTGTTCTTGTTGATCGTGC 614 41 251 Antisense
GCTCGTATCGAGTGCCAGTCGTACA 622 299 274 Antisense
GGATTCGATCATGACGGAACTCCAC 242 509 418 Antisense
CGTCTTTTCAAAACCGAGCCATCTG 453 245 442 Antisense
ATACTGTCGACGAAGCTACCACTCT 298 23 554 Antisense
GTAAAGTCGCTGGCTCAGGTCGTAC 3 461 589 Antisense
GGTCGTACCACCAGGATCACAAAAT 636 501 606 Antisense
AATCGAGGCTCTCCTGAAGGTTGTT 281 167 696 Antisense
Sequence Source Affymetrix Proprietary Database