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[192930_s_at] FK506-binding protein like

Description ZC455.10 /REP_DB=WormBase Gene ID /WP=CE23446 /GEN=fkb-4 /TR=Q23338 /GB=CAA99959.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=FK506-binding protein like
Cluster 6grp_highest_10_10 > 06      6grp_high1_10_10 > 50      6grp_highest_nonorm > 71      6grp_total > 41      4grp_total > 58      6grp_highest_sub > 04      6grp_cgc > 83      6grp_high1_sub > 03_04      6grp_cgc_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 493
1 2 3 4 range
A 186.2
(-1.5)
P 		249.2
(-0.4)
P 		443.3
(3)
P 		99.9
(-3)
A 		343
B 164.2
(-1.5)
P 		535
(3)
P 		329.6
(0.5)
P 		41.6
(-3)
A 		493
C 172.3
(-1.8)
P 		388.2
(3)
P 		342.2
(2)
P 		117.8
(-3)
A 		270
avr 174.2
(-1.3) 		390.8
(3) 		371.7
(2.6) 		86.4
(-3) 		304

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 365
1 2 3 4 5 6 range
A 162
(-2.7)
P 		260.6
(-0.7)
P 		405.7
(2.3)
P 		440.3
(3)
P 		197.6
(-2)
P 		147.6
(-3)
P 		293
B 497.7
(3)
P 		320.1
(0.1)
P 		445.5
(2.1)
P 		383.7
(1.1)
P 		320
(0.1)
P 		132.6
(-3)
P 		365
C 195.8
(-1.6)
P 		327.3
(1.7)
P 		304
(1.1)
P 		378.4
(3)
P 		250.7
(-0.2)
P 		138
(-3)
P 		240
avr 285.2
(0.3) 		302.7
(0.7) 		385.1
(2.6) 		400.8
(3) 		256.1
(-0.3) 		139.4
(-3) 		261
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 123
1 2 3 4 range
A 67.8
(0.2)
P 		54.1
(-0.7)
P 		115.9
(3)
P 		14.6
(-3)
A 		101
B 52.4
(-0.9)
P 		132.1
(3)
P 		76.4
(0.3)
P 		8.9
(-3)
A 		123
C 57
(-0.8)
P 		111.6
(2.5)
P 		119.3
(3)
P 		19.9
(-3)
A 		99
avr 59.1
(-0) 		99.3
(2.7) 		103.9
(3) 		14.5
(-3) 		89

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 143
1 2 3 4 5 6 range
A 29.9
(-3)
P 		92.7
(1.6)
P 		88.4
(1.3)
P 		111.7
(3)
P 		59.6
(-0.8)
P 		35.9
(-2.6)
P 		82
B 173.2
(3)
P 		106.5
(-0.2)
P 		108.2
(-0.2)
P 		101.6
(-0.5)
P 		130
(0.9)
P 		49.5
(-3)
P 		124
C 72.6
(-0.1)
P 		99.9
(3)
P 		77.4
(0.5)
P 		76.1
(0.3)
P 		81.1
(0.9)
P 		46.2
(-3)
P 		54
avr 91.9
(2.2) 		99.7
(3) 		91.3
(2.1) 		96.5
(2.7) 		90.2
(2) 		43.9
(-3) 		56
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192930_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13793
Sequence Type Exemplar sequence
Representative Public ID ZC455.10 NCBI
Target Description ZC455.10 /REP_DB=WormBase Gene ID /WP=CE23446 /GEN=fkb-4 /TR=Q23338 /GB=CAA99959.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=FK506-binding protein like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073796(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073796 NCBI Caenorhabditis elegans FK506-Binding protein family member (fkb-4) (fkb-4) mRNA, complete cds. 11/11 None
SNAP00000034470 ENSEMBL cdna:SNAP chromosome:CEL140:V:12787860:12790571:-1 11/11 None
GENEFINDER00000034481 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12785812:12790553:-1 10/11 None
ZC455.10 ENSEMBL cdna:known chromosome:CEL140:V:12787744:12789663:-1 gene:ZC455.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12787859-12789589(-) 100.0 100.0
Public Domain and Genome References
Gene Title FK506-binding protein like
Gene Symbol fkb-4
Ensembl ZC455.10
Entrez Gene 179752 Entrez gene
SwissProt Q23338 EMBL-EBI
WormBase CE23446 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA99958 Hypothetical protein ZC455.7 [Caenorhabditis elegans] ref|NP_506196.1| Serpentine Receptor, class E (epsilon) family member (sre-20) [Caenorhabditis elegans] 1.0E-153
blast CAA99959 Hypothetical protein ZC455.10 [Caenorhabditis elegans] ref|NP_506197.1| FK506-Binding protein family member (fkb-4) [Caenorhabditis elegans] 1.0E-148
blast CAA99959 Hypothetical protein ZC455.10 [Caenorhabditis elegans] ref|NP_506197.1| FK506-Binding protein family member (fkb-4) [Caenorhabditis elegans] 1.0E-131
blast CAE63997 Hypothetical protein CBG08591 [Caenorhabditis briggsae] 1.0E-123
blast CAA99959 Hypothetical protein ZC455.10 [Caenorhabditis elegans] ref|NP_506197.1| FK506-Binding protein family member (fkb-4) [Caenorhabditis elegans] 1.0E-122
blast CAE63997 Hypothetical protein CBG08591 [Caenorhabditis briggsae] 1.0E-114
blast CAE66693 Hypothetical protein CBG12033 [Caenorhabditis briggsae] 1.0E-91
Protein Domains
Database ID Description E-Value
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 2.0E-29
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 8.7E-38
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 2.0E-29
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 8.7E-38
Pfam IPR002892 EMBL-EBI Protein of unknown function DUF40 2.9E-43
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 2.0E-29
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 3.8E-32
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 4.6E-25
Pfam IPR002892 EMBL-EBI Protein of unknown function DUF40 1.6E-32
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000034470 2 47-66,79-101
GENEFINDER00000034481 9 41-60,73-95,340-362,375-397,412-434,455-477,482-504,544-566,581-598
Sequence
Target Sequence 
>C. ELEGANS:192930_S_AT
ggtggcgatgtagttgatcagtactacaagttgacagatgagaagggagttgaaattgga
agcaattttggaaagaaaccatatacattcacgttgggaaggaatcaagtgatacctgga
atggatagagctatgcgaggaatgtgtattggagagattcgaaaagttgtgattcccccg
aaactaggatttgcgaaagactcgactggtcagccactctattacactgtccagctggtg
aacctgttccgtgcgaatcctggggagagatgggtcactgaagaaggaattcaaattgat
cagattcacaagattgaagcagacaaatgtaaaaaagctgaagctggcgacaagatttat
cagcaatatgttttgagattagaagataacacacttgtggactcatcttattcaagaaat
gctccgtttgtatttagattgagaaacagagaagttatcgatggaatggatattgcaatg
gatggaatgtgtgaaggagaacgacgtcgtgttgtgattccatctgaatatggatacgga
tcccaaggatccccaccagagattcccggtggtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTGGCGATGTAGTTGATCAGTACT 20 499 163 Antisense
GATTCGAAAAGTTGTGATTCCCCCG 195 425 318 Antisense
GATTCCCCCGAAACTAGGATTTGCG 83 319 333 Antisense
CCACTCTATTACACTGTCCAGCTGG 283 275 376 Antisense
ACACTGTCCAGCTGGTGAACCTGTT 308 109 386 Antisense
TGTTCCGTGCGAATCCTGGGGAGAG 65 563 407 Antisense
GCTGAAGCTGGCGACAAGATTTATC 26 297 499 Antisense
AACACACTTGTGGACTCATCTTATT 543 135 550 Antisense
AATGCTCCGTTTGTATTTAGATTGA 543 165 580 Antisense
GAACGACGTCGTGTTGTGATTCCAT 687 345 661 Antisense
TCCCCACCAGAGATTCCCGGTGGTG 577 593 712 Antisense
Sequence Source Affymetrix Proprietary Database