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[192919_s_at]

Description F11A6.1A /REP_DB=WormBase Gene ID /WP=CE17653 /GEN=kpc-1 /TR=O17797 /GB=CAB04086.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Furin like serine protease
Cluster 6grp_highest_10_10 > 84      6grp_high1_10_10 > 47      4grp_highest_8_8 > 31      4grp_high_8_8 > 05      6grp_highest_nonorm > 84      6grp_total > 48      4grp_total > 03      6grp_highest_sub > Cu      6grp_cgc > 17      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1925
1 2 3 4 range
A 970.2
(-1.8)
P 		838.2
(-2.3)
P 		598.4
(-3)
P 		2523
(3)
P 		1925
B 1073.7
(-2.1)
P 		827.6
(-3)
P 		937.9
(-2.6)
P 		2464.3
(3)
P 		1637
C 961.3
(-2.2)
P 		796.8
(-2.8)
P 		749.9
(-3)
P 		2347.8
(3)
P 		1598
avr 1001.7
(-2.1) 		820.9
(-2.8) 		762.1
(-3) 		2445
(3) 		1683

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 498
1 2 3 4 5 6 range
A 864.9
(2.6)
P 		713.3
(0.4)
P 		591.8
(-1.4)
P 		485.4
(-3)
P 		552.9
(-2)
P 		889.6
(3)
P 		404
B 698.7
(2.3)
P 		595.1
(0.5)
P 		391.5
(-3)
P 		685.1
(2.1)
P 		560.7
(-0.1)
P 		736.7
(3)
P 		345
C 756.3
(2.1)
P 		696.3
(1.1)
P 		546.7
(-1.4)
P 		446.9
(-3)
P 		511.1
(-1.9)
P 		812.3
(3)
P 		365
avr 773.3
(2.2) 		668.2
(0.1) 		510
(-3) 		539.1
(-2.4) 		541.6
(-2.4) 		812.9
(3) 		303
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 369
1 2 3 4 range
A 353.2
(2.5)
P 		181.9
(-2.3)
P 		156.4
(-3)
P 		369.3
(3)
P 		213
B 342.4
(-0.4)
P 		204.4
(-3)
P 		217.3
(-2.8)
P 		525.1
(3)
P 		321
C 318.2
(0.2)
P 		229.1
(-3)
P 		261.4
(-1.8)
P 		395.9
(3)
P 		167
avr 337.9
(0.5) 		205.1
(-3) 		211.7
(-2.8) 		430.1
(3) 		225

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 190
1 2 3 4 5 6 range
A 159.4
(-1.3)
P 		253.7
(3)
P 		128.9
(-2.7)
P 		123.1
(-3)
P 		166.8
(-1)
P 		216.6
(1.3)
P 		131
B 243.1
(1.9)
P 		198.1
(0.4)
P 		95.1
(-3)
P 		181.5
(-0.1)
P 		227.8
(1.4)
P 		274.7
(3)
P 		180
C 280.3
(3)
P 		212.5
(0.9)
P 		139.1
(-1.4)
P 		89.9
(-3)
P 		165.4
(-0.6)
P 		271.9
(2.7)
P 		190
avr 227.6
(1.8) 		221.4
(1.5) 		121
(-3) 		131.5
(-2.5) 		186.7
(-0) 		254.4
(3) 		133
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192919_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1135
Sequence Type Exemplar sequence
Representative Public ID F11A6.1A NCBI
Target Description F11A6.1A /REP_DB=WormBase Gene ID /WP=CE17653 /GEN=kpc-1 /TR=O17797 /GB=CAB04086.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Furin like serine protease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060573(11), NM_001025929(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060573 NCBI Caenorhabditis elegans Kex-2 Proprotein Convertase family member (kpc-1) (kpc-1) mRNA, complete cds. 11/11 A 
NM_001025929 NCBI Caenorhabditis elegans Kex-2 Proprotein Convertase family member (kpc-1) (kpc-1) mRNA, complete cds. 11/11 None
SNAP00000041218 ENSEMBL cdna:SNAP chromosome:CEL140:I:11684167:11688754:1 11/11 None
GENEFINDER00000041221 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:11688016:11688754:1 10/11 None
F11A6.1a ENSEMBL cdna:known chromosome:CEL140:I:11684065:11688874:1 gene:F11A6.1 11/11 A 
F11A6.1b ENSEMBL cdna:known chromosome:CEL140:I:11684066:11689089:1 gene:F11A6.1 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000041223 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:11684097-11688685(+) 99.86 100.0
Public Domain and Genome References
Ensembl F11A6.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB04086 Hypothetical protein F11A6.1a [Caenorhabditis elegans] ref|NP_492974.2| Kex-2 Proprotein Convertase family member (kpc-1) [Caenorhabditis elegans] 0.0
blast AAB63525 celfur protein 0.0
blast CAB04085 Hypothetical protein F11A6.1b [Caenorhabditis elegans] ref|NP_001021101.1| Kex-2 Proprotein Convertase family member (kpc-1) [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 6.3E-74
Pfam IPR000209 EMBL-EBI Peptidase S8 and S53, subtilisin, kexin, sedolisin 1.0E-126
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 1.7E-65
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 1.7E-65
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000041221 1 159-176
Sequence
Target Sequence 
>C. ELEGANS:192919_S_AT
gtgcaggcagttttatccgtcgagatataaaaatatccccaacggaaaccgccttcaact
ccaactttactccgacggatgttatggtggagccgatgagaataaggtgtcttatgtgga
gcacgtgcaggcaatcgtcacattgaaagctccaaaacgtggagatttgcaaatctactt
gacttctccgtcaggcacaaaatccacgttgctcacaaaaagagcacgcgacacatcacg
aagtggcttcacagattgggctttcatgacgacccataactggggggagcaggccgccgg
gctgtggattctggaaatcgataatgatggatgggatgacgccgagcttgtaaaatggga
actcgtgctctacggaactgatcgggaaaccggcgactttggaggccaacatgcttcacc
gttagccgtcagaagtgtccagatggaagccacgtcatccggcacccaatattcaatttt
ccacgtcatcact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGCAGGCAGTTTTATCCGTCGAGA 642 479 1563 Antisense
CTCCAACTTTACTCCGACGGATGTT 412 235 1621 Antisense
TGGAGCACGTGCAGGCAATCGTCAC 245 549 1679 Antisense
TGCAAATCTACTTGACTTCTCCGTC 303 577 1730 Antisense
GACTTCTCCGTCAGGCACAAAATCC 637 369 1743 Antisense
GCACGCGACACATCACGAAGTGGCT 45 315 1786 Antisense
GTGGCTTCACAGATTGGGCTTTCAT 443 491 1805 Antisense
GCTTTCATGACGACCCATAACTGGG 59 305 1822 Antisense
GAACTCGTGCTCTACGGAACTGATC 337 347 1921 Antisense
CCGTTAGCCGTCAGAAGTGTCCAGA 273 261 1981 Antisense
ATATTCAATTTTCCACGTCATCACT 197 19 2031 Antisense
Sequence Source Affymetrix Proprietary Database