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[192906_at] transient receptor protein

Description T01H8.5 /REP_DB=WormBase Gene ID /WP=CE13022 /GEN=gon-2 /TR=Q93971 /GB=CAB02303.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=transient receptor protein
Cluster 6grp_highest_10_10 > 74      6grp_high1_10_10 > 47      4grp_highest_8_8 > 38      4grp_high_8_8 > 03      6grp_highest_nonorm > 81      6grp_total > 47      4grp_total > 06      6grp_highest_sub > Cu      6grp_cgc > 17      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 207
1 2 3 4 range
A 269.4
(-2.9)
P 		267.1
(-3)
P 		284.4
(-2.4)
P 		452.6
(3)
P 		186
B 411.4
(1.8)
P 		271
(-3)
P 		288.9
(-2.4)
P 		445.9
(3)
P 		175
C 348.9
(3)
P 		245.5
(-3)
P 		289
(-0.5)
P 		334.3
(2.2)
P 		103
avr 343.2
(0.3) 		261.2
(-3) 		287.4
(-1.9) 		410.9
(3) 		150

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 162
1 2 3 4 5 6 range
A 277.6
(0.8)
P 		268.8
(-0.3)
P 		247.3
(-3)
P 		250.1
(-2.6)
P 		260.4
(-1.4)
P 		295.1
(3)
P 		48
B 289
(2.9)
P 		290.4
(3)
P 		281.1
(2.3)
P 		212.7
(-3)
P 		270.4
(1.5)
P 		288.7
(2.9)
P 		78
C 361.4
(2.4)
P 		282.9
(-1)
P 		273.7
(-1.4)
P 		296.8
(-0.4)
P 		237.8
(-3)
P 		374.4
(3)
P 		137
avr 309.3
(2.1) 		280.7
(-0.5) 		267.4
(-1.7) 		253.2
(-3) 		256.2
(-2.7) 		319.4
(3) 		66
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 75
1 2 3 4 range
A 98.1
(3)
P 		58
(-3)
P 		74.3
(-0.6)
P 		66.3
(-1.8)
P 		40
B 131.2
(3)
P 		66.9
(-3)
P 		66.9
(-3)
P 		95
(-0.4)
P 		64
C 115.5
(3)
P 		70.6
(-1.6)
P 		100.7
(1.5)
P 		56.4
(-3)
P 		59
avr 114.9
(3) 		65.2
(-3) 		80.6
(-1.1) 		72.6
(-2.1) 		50

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 83
1 2 3 4 5 6 range
A 51.2
(-3)
P 		95.6
(3)
P 		53.9
(-2.6)
P 		63.4
(-1.4)
P 		78.6
(0.7)
P 		71.9
(-0.2)
P 		44
B 100.6
(2)
P 		96.7
(1.5)
P 		68.3
(-1.7)
P 		56.3
(-3)
P 		109.9
(3)
P 		107.7
(2.8)
P 		54
C 133.9
(3)
P 		86.3
(-0.8)
P 		69.7
(-2.2)
P 		59.7
(-3)
P 		76.9
(-1.6)
P 		125.3
(2.3)
P 		74
avr 95.2
(2.1) 		92.9
(1.8) 		64
(-2.4) 		59.8
(-3) 		88.5
(1.1) 		101.6
(3) 		42
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192906_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.494
Sequence Type Exemplar sequence
Representative Public ID T01H8.5 NCBI
Target Description T01H8.5 /REP_DB=WormBase Gene ID /WP=CE13022 /GEN=gon-2 /TR=Q93971 /GB=CAB02303.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=transient receptor protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059914(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059914 NCBI Caenorhabditis elegans abnormal GONad development family member (gon-2) (gon-2) mRNA, complete cds. 11/11 A 
T01H8.5 ENSEMBL cdna:known chromosome:CEL140:I:8557655:8579082:-1 gene:T01H8.5 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000010896 6/11 Cross Hyb Matching Probes None
GENEFINDER00000010904 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8558004-8567864(-) 99.32 100.0
Public Domain and Genome References
Gene Title transient receptor protein
Gene Symbol gon-2
Ensembl T01H8.5
Entrez Gene 172646 Entrez gene
SwissProt Q93971 EMBL-EBI
WormBase CE30390 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.16158.1.S1_AT similar to transient receptor potential cation channel, subfamily M, member 1 cfa
CANINE_2:CFAAFFX.16161.1.S1_S_AT similar to transient receptor potential cation channel, subfamily M, member 1 cfa
CHICKEN:GGAAFFX.2399.1.S1_S_AT similar to transient receptor potential cation channel, subfamily M, member 1; melastatin 1 gga
CHICKEN:GGAAFFX.2399.2.S1_AT similar to transient receptor potential cation channel, subfamily M, member 1; melastatin 1 gga
CHICKEN:GGAAFFX.2399.3.S1_S_AT similar to transient receptor potential cation channel, subfamily M, member 1; melastatin 1 gga
HG-U133_PLUS_2:206479_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133A:206479_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133A_2:206479_AT transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBA:AA455860_S_AT transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBC:RC_N20535_AT transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBC:RC_N21111_AT transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBC:RC_AA436463_AT transient receptor potential cation channel, subfamily M, member 1 hs
U133_X3P:G6006023_3P_AT transient receptor potential cation channel, subfamily M, member 1 hs
U133_X3P:HS.166845.0.A1_3P_S_AT transient receptor potential cation channel, subfamily M, member 1 hs
U133_X3P:HS.166845.0.A1_3P_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133_PLUS_2:237069_S_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133B:237069_S_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133_PLUS_2:237070_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133B:237070_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95AV2:41564_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95B:49609_R_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95C:62717_AT transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133_PLUS_2:214410_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133A_2:214410_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-FOCUS:214410_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133A:214410_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133_PLUS_2:240386_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133B:240386_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133_PLUS_2:243741_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U133B:243741_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95AV2:41563_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95B:44502_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95C:52604_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95C:66560_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95D:81181_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95E:82726_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95D:87766_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95D:88401_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HG-U95D:91463_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBA:N28643_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBC:RC_N31576_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBC:RC_AA458649_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBC:RC_H98835_AT Transient receptor potential cation channel, subfamily M, member 1 hs
HU35KSUBC:RC_N23401_AT Transient receptor potential cation channel, subfamily M, member 1 hs
U133_X3P:HS.145268.0.A1_3P_AT Transient receptor potential cation channel, subfamily M, member 1 hs
U133_X3P:HS.40930.0.A1_3P_AT Transient receptor potential cation channel, subfamily M, member 1 hs
U133_X3P:HS.43265.1.A1_3P_AT Transient receptor potential cation channel, subfamily M, member 1 hs
RAT230_2:1375596_AT similar to transient receptor potential cation channel, subfamily M, member 1 rn
RAE230A:1375596_AT similar to transient receptor potential cation channel, subfamily M, member 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
6812 cation transport inferred from sequence similarity QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
5886 plasma membrane inferred from sequence similarity QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
8324 cation transporter activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02303 Hypothetical protein T01H8.5 [Caenorhabditis elegans] emb|CAB05572.2| Hypothetical protein T01H8.5 [Caenorhabditis elegans] ref|NP_492315.4| abnormal GONad development family member (gon-2) [Caenorhabditis elegans] sp|Q93971|TRPG_CAEEL Transient receptor potential channel (Abnormal gonad development protein 2) 0.0
blast CAC81668 putative TRP homologous cation channel [Caenorhabditis elegans] 0.0
blast T23707 hypothetical protein T01H8.5 - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 3.3E-19
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492315.4 5 1308-1330,1337-1355,1370-1392,1443-1465,1537-1559
T01H8.5 5 1308-1330,1337-1355,1370-1392,1443-1465,1537-1559
Sequence
Target Sequence 
>C. ELEGANS:192906_AT
cctctcgccaaactgtcaacaatgtcgattcgccgccgacacgaggagtatacatcaatc
actgattcaatcgcaatacgacatcctgaacgaagaattcgaaataatcgatcgaatagt
agtgaacatgatgaatcagcagttgattcagagggaggtggcaatgtaacgtcatcacca
aggaagcggtcgacaagagatcttcgaatgactccgtcttctcaagttgaagaatcaact
agtagggatcaaatattcgaaattgatcaccccgaacacgaggaagacgaggctcaggca
gattgtgaactaactgatgtgatcactgaagaagaagacgaggaagaagatgatgaggaa
gatgatagtcatgaaaggcatcatattcatcccagaaggaaatcatcacgacagaataga
caaccatcacatacactggaaactgatttgtccgaaggagaggaagttgatccattggat
gttctgaaaatgaaagaactgccaattattcaccaaattttgaacgaagaagagcaggcc
ggggctcctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCTCTCGCCAAACTGTCAACAATGT 583 267 4996 Antisense
TTCGCCGCCGACACGAGGAGTATAC 20 685 5024 Antisense
GATTCAATCGCAATACGACATCCTG 137 431 5059 Antisense
GAGGGAGGTGGCAATGTAACGTCAT 31 403 5146 Antisense
ACGTCATCACCAAGGAAGCGGTCGA 349 95 5164 Antisense
CTTCGAATGACTCCGTCTTCTCAAG 258 219 5197 Antisense
AATTGATCACCCCGAACACGAGGAA 411 173 5256 Antisense
GACGAGGCTCAGGCAGATTGTGAAC 381 379 5281 Antisense
GAAAGGCATCATATTCATCCCAGAA 373 361 5368 Antisense
GAATAGACAACCATCACATACACTG 185 327 5409 Antisense
GAAGAAGAGCAGGCCGGGGCTCCTC 585 337 5521 Antisense
Sequence Source Affymetrix Proprietary Database