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[192885_s_at] Human host cell factor C1 like protein

Description F53E4.1 /REP_DB=WormBase Gene ID /WP=CE20848 /TR=O17718 /GB=CAB03122.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Human host cell factor C1 like protein
Cluster 6grp_highest_10_10 > 99      6grp_high1_10_10 > 97      4grp_highest_8_8 > 12      4grp_high_8_8 > 31      6grp_highest_nonorm > 93      6grp_total > 96      4grp_total > 32      6grp_high1_sub > In      6grp_total_sub > Increase      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 445
1 2 3 4 range
A 360.9
(-3)
P 		519.7
(-0.7)
P 		772.5
(2.9)
P 		781.6
(3)
P 		421
B 343.2
(-3)
P 		532.9
(-0.3)
P 		698.4
(2)
P 		766
(3)
P 		423
C 336.6
(-3)
P 		648.5
(3)
P 		560.7
(1.3)
P 		556.1
(1.2)
P 		312
avr 346.9
(-3) 		567
(0.7) 		677.2
(2.6) 		701.2
(3) 		354

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 512
1 2 3 4 5 6 range
A 294.5
(-2.5)
P 		430
(-0.9)
P 		257.4
(-3)
P 		422.7
(-1)
P 		744.5
(3)
P 		656
(1.9)
P 		487
B 349.3
(-1.3)
P 		389.4
(-0.7)
P 		232.4
(-3)
P 		462.5
(0.4)
P 		520.6
(1.2)
P 		641.3
(3)
P 		409
C 441.6
(0.8)
P 		318.9
(-2.6)
P 		303.3
(-3)
P 		406.7
(-0.1)
P 		372.1
(-1.1)
P 		520.4
(3)
P 		217
avr 361.8
(-1.3) 		379.4
(-1) 		264.4
(-3) 		430.6
(-0.1) 		545.7
(1.9) 		605.9
(3) 		342
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 108
1 2 3 4 range
A 131.4
(-1.7)
P 		112.8
(-3)
P 		201.9
(3)
P 		114.4
(-2.9)
P 		89
B 109.4
(-3)
P 		131.6
(-0.5)
P 		161.8
(2.8)
P 		163.2
(3)
P 		54
C 111.4
(-2)
P 		186.4
(2.5)
P 		195.4
(3)
P 		93.8
(-3)
P 		102
avr 117.4
(-3) 		143.6
(-0.7) 		186.4
(3) 		123.8
(-2.4) 		69

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 185
1 2 3 4 5 6 range
A 54.3
(-3)
P 		152.9
(0.5)
P 		56.1
(-2.9)
P 		107.2
(-1.1)
P 		224.6
(3)
P 		159.7
(0.7)
P 		170
B 121.5
(-0.9)
P 		129.6
(-0.6)
P 		56.4
(-3)
P 		122.5
(-0.8)
P 		211.5
(2.1)
P 		239.1
(3)
P 		183
C 163.7
(2.4)
P 		97.3
(-1.8)
P 		77.2
(-3)
P 		81.8
(-2.7)
P 		120.4
(-0.3)
P 		174.2
(3)
P 		97
avr 113.2
(-0.7) 		126.6
(-0) 		63.2
(-3) 		103.8
(-1.1) 		185.5
(2.7) 		191
(3) 		128
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192885_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12661
Sequence Type Exemplar sequence
Representative Public ID F53E4.1 NCBI
Target Description F53E4.1 /REP_DB=WormBase Gene ID /WP=CE20848 /TR=O17718 /GB=CAB03122.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Human host cell factor C1 like protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074494(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074494 NCBI Caenorhabditis elegans F53E4.1 (F53E4.1) mRNA, complete cds. 11/11 None
F53E4.1 ENSEMBL cdna:known chromosome:CEL140:V:15655082:15661651:-1 gene:F53E4.1 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000026332 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15655369-15661645(-) 100.0 100.0
Public Domain and Genome References
Gene Title Human host cell factor C1 like protein
Ensembl F53E4.1
Entrez Gene 180050 Entrez gene
SwissProt O17718 EMBL-EBI
WormBase CE20848 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:255769_AT kelch repeat-containing protein at
CANINE:1583568_AT similar to kelch domain containing 3 (predicted) cfa
CANINE:1584537_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFA.16400.1.A1_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFA.18469.1.S1_S_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFA.3935.1.A1_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFAAFFX.3548.1.S1_S_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFAAFFX.3553.1.S1_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFAAFFX.3554.1.S1_S_AT similar to kelch domain containing 3 (predicted) cfa
DROSOPHILA_2:1626154_AT dm
DROSGENOME1:153965_AT dm
CHICKEN:GGA.15874.1.S1_AT kelch domain containing 3 gga
HG-U133A:208784_S_AT kelch domain containing 3 hs
HG-U133_PLUS_2:208784_S_AT kelch domain containing 3 hs
HG-U133A_2:208784_S_AT kelch domain containing 3 hs
HUGENEFL:X98248_RNA1_AT kelch domain containing 3 hs
U133_X3P:G12804724_3P_X_AT kelch domain containing 3 hs
U133_X3P:HS.281706.2.S1_3P_A_AT kelch domain containing 3 hs
HG-U133A_2:214383_X_AT kelch domain containing 3 hs
HG-U133_PLUS_2:214383_X_AT kelch domain containing 3 hs
HG-U133A:214383_X_AT kelch domain containing 3 hs
HG-U95AV2:39537_AT kelch domain containing 3 hs
HG-U95D:82804_AT kelch domain containing 3 hs
MOE430A:1448164_AT kelch domain containing 3 mm
MOUSE430A_2:1448164_AT kelch domain containing 3 mm
MOUSE430_2:1448164_AT kelch domain containing 3 mm
MOUSE430_2:1415991_A_AT kelch domain containing 3 mm
MOUSE430A_2:1415991_A_AT kelch domain containing 3 mm
MOE430A:1415991_A_AT kelch domain containing 3 mm
MOUSE430A_2:1455910_AT kelch domain containing 3 mm
MOE430A:1455910_AT kelch domain containing 3 mm
MOUSE430_2:1455910_AT kelch domain containing 3 mm
MOE430A:1454747_A_AT kelch domain containing 3 mm
MOUSE430A_2:1454747_A_AT kelch domain containing 3 mm
MOUSE430_2:1454747_A_AT kelch domain containing 3 mm
MU19KSUBC:TC37515_AT Kelch domain containing 3, mRNA (cDNA clone MGC:25567 IMAGE:3983436) mm
Protein Similarities
Method ID Description E-Value
blast CAB04012 Hypothetical protein F53E4.1 [Caenorhabditis elegans] emb|CAB03122.1| Hypothetical protein F53E4.1 [Caenorhabditis elegans] ref|NP_506895.1| F53E4.1 [Caenorhabditis elegans] 0.0
blast CAE61037 Hypothetical protein CBG04780 [Caenorhabditis briggsae] 0.0
blast AAI03003 Kelch domain containing 3 [Bos taurus] ref|NP_001014966.1| kelch domain containing 3 [Bos taurus] gb|AAX08673.1| testis intracellular mediator protein [Bos taurus] 2.0E-85
Protein Domains
Database ID Description E-Value
Pfam IPR006652 EMBL-EBI Kelch repeat 9.7E-6
Pfam IPR006652 EMBL-EBI Kelch repeat 4.7E-6
Pfam IPR006652 EMBL-EBI Kelch repeat 7.2E-8
Pfam IPR006652 EMBL-EBI Kelch repeat 1.7E-4
Pfam IPR006652 EMBL-EBI Kelch repeat 5.8E-7
Pfam IPR006652 EMBL-EBI Kelch repeat 3.7E-4
Sequence
Target Sequence 
>C. ELEGANS:192885_S_AT
caggtcggtgacgagcacttgttccacacgattcatgatcaatatgacgatacattgatg
gcattgaatttggcaactggagcatggacacggacaaaagtaccggaaaatacgatgaag
cccggcggtcggcgtagtcattcgacgtgggtctacgatggaaaaatgtacatgtttggc
ggttatttgggaacgattaatgtacactacaatgaactgtactgttttgatccaaaaacg
tcgatgtggagtgttatttcggtccgaggcacatacccatcagctcgccggcgtcactgt
tcggtggtctcgaacggaaaagtgtaccttttcggtggaacgatgccgctaccgtgtcat
ccactctccactacaaactacaatggaatgatctcacccagtggacttgccgatttatct
gatcttcatgttcttgattttgctccatccctgaaaacgttggcaatgcaaagtgtgctc
aatgagctcaaggtgccatcaaaaggaatgttcgaaacgctccaaaacgagcttgccgct
gatattcgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAGGTCGGTGACGAGCACTTGTTCC 423 207 670 Antisense
GCACTTGTTCCACACGATTCATGAT 203 315 684 Antisense
GGCAACTGGAGCATGGACACGGACA 282 533 741 Antisense
GGCGTAGTCATTCGACGTGGGTCTA 482 539 800 Antisense
GTGGAGTGTTATTTCGGTCCGAGGC 212 489 915 Antisense
TTTTCGGTGGAACGATGCCGCTACC 450 597 998 Antisense
GAATGATCTCACCCAGTGGACTTGC 552 331 1055 Antisense
GACTTGCCGATTTATCTGATCTTCA 433 371 1073 Antisense
TCATGTTCTTGATTTTGCTCCATCC 160 623 1095 Antisense
TGCTCCATCCCTGAAAACGTTGGCA 523 581 1110 Antisense
AACGAGCTTGCCGCTGATATTCGAT 442 145 1195 Antisense
Sequence Source Affymetrix Proprietary Database