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[192882_at] glucose-6-phosphate-1-dehydrogenase

Description B0035.5 /REP_DB=WormBase Gene ID /WP=CE05163 /TR=SW:Q27464 /GB=CAA97412.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=glucose-6-phosphate-1-dehydrogenase
Cluster 6grp_highest_10_10 > 45      6grp_high1_10_10 > 54      4grp_highest_8_8 > 42      4grp_high_8_8 > 48      6grp_highest_nonorm > 67      6grp_total > 54      4grp_total > 55      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 601
1 2 3 4 range
A 1769.4
(3)
P 		1333.1
(-1.8)
P 		1399.2
(-1.1)
P 		1226.9
(-3)
P 		543
B 1637.1
(3)
P 		1421.3
(-1.5)
P 		1421.8
(-1.4)
P 		1346.5
(-3)
P 		291
C 1827.8
(3)
P 		1293.2
(-3)
P 		1508.2
(-0.6)
P 		1332.7
(-2.6)
P 		535
avr 1744.8
(3) 		1349.2
(-2.4) 		1443.1
(-1.1) 		1302
(-3) 		443

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1298
1 2 3 4 5 6 range
A 1717.1
(-0.2)
P 		1797
(0.3)
P 		2304.5
(3)
P 		1845
(0.5)
P 		1186.9
(-3)
P 		1783
(0.2)
P 		1118
B 1592.9
(-1.5)
P 		2150.1
(2.8)
P 		2179.5
(3)
P 		1871.9
(0.6)
P 		1399.6
(-3)
P 		1982.6
(1.5)
P 		780
C 1557.8
(-1.4)
P 		2168.7
(1.5)
P 		2485.3
(3)
P 		1825.9
(-0.1)
P 		1211.8
(-3)
P 		1877.4
(0.1)
P 		1274
avr 1622.6
(-1) 		2038.6
(1.4) 		2323.1
(3) 		1847.6
(0.3) 		1266.1
(-3) 		1881
(0.5) 		1057
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 465
1 2 3 4 range
A 644.3
(3)
P 		289.4
(-1.6)
P 		365.8
(-0.6)
P 		179.6
(-3)
P 		465
B 522.1
(3)
P 		351
(-1.4)
P 		329.5
(-1.9)
P 		286.9
(-3)
P 		235
C 605.1
(3)
P 		371.8
(-0.7)
P 		525.6
(1.7)
P 		224.7
(-3)
P 		380
avr 590.5
(3) 		337.4
(-1.2) 		407
(-0.1) 		230.4
(-3) 		360

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 423
1 2 3 4 5 6 range
A 316.5
(-3)
P 		639.1
(3)
P 		501.9
(0.4)
P 		467.9
(-0.2)
P 		358.2
(-2.2)
P 		434.1
(-0.8)
P 		323
B 554.3
(-1.6)
P 		715.7
(2.4)
P 		529.3
(-2.2)
P 		495.8
(-3)
P 		568.6
(-1.2)
P 		739.3
(3)
P 		244
C 577.4
(1.3)
P 		661.7
(3)
P 		632.5
(2.4)
P 		367.2
(-3)
P 		392.1
(-2.5)
P 		628.5
(2.3)
P 		295
avr 482.7
(-1.9) 		672.2
(3) 		554.6
(-0) 		443.6
(-2.9) 		439.6
(-3) 		600.6
(1.2) 		233
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192882_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9606
Sequence Type Exemplar sequence
Representative Public ID B0035.5 NCBI
Target Description B0035.5 /REP_DB=WormBase Gene ID /WP=CE05163 /TR=SW:Q27464 /GB=CAA97412.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=glucose-6-phosphate-1-dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069728(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069728 NCBI Caenorhabditis elegans B0035.5 (glucose-6-phosphate-1-dehydrogenase) mRNA, complete cds. 11/11 None
SNAP00000035834 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11317392:11319748:1 11/11 None
GENEFINDER00000035857 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11317392:11319748:1 10/11 None
B0035.5.2 ENSEMBL cdna:known chromosome:CEL140:IV:11317388:11319905:1 gene:B0035.5 11/11 None
B0035.5.1 ENSEMBL cdna:known chromosome:CEL140:IV:11317390:11319905:1 gene:B0035.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11317397-11319754(+) 100.0 100.0
Public Domain and Genome References
Gene Title glucose-6-phosphate-1-dehydrogenase
Ensembl B0035.5
Entrez Gene 178046 Entrez gene
SwissProt Q27464 EMBL-EBI
WormBase CE05163 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:18021_AT glucose-6-phosphate 1-dehydrogenase / G6PD (ACG9) at
ATH1-121501:257144_AT glucose-6-phosphate 1-dehydrogenase / G6PD (ACG9) at
CANINE:1584657_AT similar to Glucose-6-phosphate 1-dehydrogenase (G6PD) cfa
CANINE_2:CFA.12132.1.A1_AT similar to Glucose-6-phosphate 1-dehydrogenase (G6PD) cfa
CANINE_2:CFA.18988.1.S1_S_AT similar to Glucose-6-phosphate 1-dehydrogenase (G6PD) cfa
CANINE_2:CFAAFFX.29972.1.S1_AT similar to Glucose-6-phosphate 1-dehydrogenase (G6PD) cfa
DROSOPHILA_2:1625995_A_AT Zwischenferment dm
DROSGENOME1:141547_AT Zwischenferment dm
HG-U133_PLUS_2:202275_AT glucose-6-phosphate dehydrogenase hs
HG-U133A_2:202275_AT glucose-6-phosphate dehydrogenase hs
HG-U133A:202275_AT glucose-6-phosphate dehydrogenase hs
HUGENEFL:X55448_CDS1_S_AT glucose-6-phosphate dehydrogenase hs
U133_X3P:G4503844_3P_AT glucose-6-phosphate dehydrogenase hs
MOE430A:1422327_S_AT glucose-6-phosphate dehydrogenase X-linked mm
MOUSE430_2:1422327_S_AT glucose-6-phosphate dehydrogenase X-linked mm
MOUSE430A_2:1422327_S_AT glucose-6-phosphate dehydrogenase X-linked mm
MU11KSUBB:Z11911_S_AT glucose-6-phosphate dehydrogenase X-linked mm
MG-U74AV2:94966_AT glucose-6-phosphate dehydrogenase X-linked mm
MG-U74AV2:101294_G_AT glucose-6-phosphate dehydrogenase X-linked mm
MG-U74BV2:105780_AT glucose-6-phosphate dehydrogenase X-linked mm
MOE430A:1448354_AT glucose-6-phosphate dehydrogenase X-linked mm
MOUSE430A_2:1448354_AT glucose-6-phosphate dehydrogenase X-linked mm
MOUSE430_2:1448354_AT glucose-6-phosphate dehydrogenase X-linked mm
MU19KSUBB:TC28383_S_AT Glucose-6-phosphate dehydrogenase X-linked (G6pdx), mRNA mm
RT-U34:X07467_AT glucose-6-phosphate dehydrogenase rn
RG-U34A:X07467_AT glucose-6-phosphate dehydrogenase rn
RAE230A:1367856_AT glucose-6-phosphate dehydrogenase rn
RAT230_2:1367856_AT glucose-6-phosphate dehydrogenase rn
YEAST_2:1776427_AT Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6006 glucose metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4345 glucose-6-phosphate 1-dehydrogenase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA97412 Hypothetical protein B0035.5 [Caenorhabditis elegans] ref|NP_502129.1| B0035.5 [Caenorhabditis elegans] sp|Q27464|G6PD_CAEEL Glucose-6-phosphate 1-dehydrogenase (G6PD) 0.0
blast CAE62054 Hypothetical protein CBG06072 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001282 EMBL-EBI Glucose-6-phosphate dehydrogenase 1.0E-126
Pfam IPR001282 EMBL-EBI Glucose-6-phosphate dehydrogenase 3.8E-116
Pfam IPR001282 EMBL-EBI Glucose-6-phosphate dehydrogenase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192882_AT
tgccagtcctgaatttgatcacccagaagcatcacaaggatacaaagatgacaaatcagt
tccagccgattcgactactccaacgtatgctcttgctgttgttcacatcaataatgaacg
ttgggagggtgttccattcttcttgcgttgtggaaaagctctcaacgagaagaaagcaga
agttcgtatacaattcaaagaagtcagtggagatatctatccgtctggtgaattaaagcg
atccgaattagtgatgagagtgcaaccaaatgaggcagtttacatgaaactgatgaccaa
gaaacctggaatgggattcggtgttgaagaaactgaacttgatttgacttataataatag
attcaaagaagtccgtcttcctgatgcttatgaacgcctatttctcgaagtattcatggg
atctcaaattaatttcgttcgaactgatgagcttgaatacgcttggcgtattttgacgcc
agttctcgaagagcttaaaaagaagaaagttcaaccggttcaatataaatttggaagtcg
tggtccaactgaaggtgacgaattgatgaaaaagtacggtttcatcttcactgga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCCAGTCCTGAATTTGATCACCCA 567 585 957 Antisense
CAAATCAGTTCCAGCCGATTCGACT 26 193 1008 Antisense
ATTCGACTACTCCAACGTATGCTCT 433 5 1025 Antisense
TGTTCCATTCTTCTTGCGTTGTGGA 19 563 1086 Antisense
GGAGATATCTATCCGTCTGGTGAAT 477 517 1165 Antisense
AAAGAAGTCCGTCTTCCTGATGCTT 637 121 1321 Antisense
GATGCTTATGAACGCCTATTTCTCG 107 413 1339 Antisense
GATGAGCTTGAATACGCTTGGCGTA 215 411 1402 Antisense
CGTATTTTGACGCCAGTTCTCGAAG 285 247 1423 Antisense
GGAAGTCGTGGTCCAACTGAAGGTG 645 529 1489 Antisense
AAAGTACGGTTTCATCTTCACTGGA 191 121 1527 Antisense
Sequence Source Affymetrix Proprietary Database