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[192870_at] CDC2/CDC28 subfamily of ser/thr protein kinases

Description C36B7.1 /REP_DB=WormBase Gene ID /WP=CE04172 /GB=AAK68227.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=CDC2-CDC28 subfamily of ser-thr protein kinases
Cluster 6grp_total > 90      4grp_total > 30      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 38
1 2 3 4 range
A 31.4
(1.8)
A 		36.2
(3)
A 		13.1
(-3)
A 		16.9
(-2)
A 		23
B 39.3
(3)
A 		6
(-3)
A 		12.7
(-1.8)
A 		9.3
(-2.4)
A 		33
C 7.9
(-3)
A 		9.6
(-2.7)
A 		9.1
(-2.8)
A 		43.8
(3)
A 		36
avr 26.2
(3) 		17.3
(-0.7) 		11.6
(-3) 		23.3
(1.8) 		15

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 62
1 2 3 4 5 6 range
A 24.6
(2.1)
A 		8
(-2.4)
A 		5.8
(-3)
A 		6.8
(-2.7)
A 		28
(3)
A 		10
(-1.9)
A 		22
B 7.7
(-2.6)
A 		8.9
(-2.5)
A 		10.4
(-2.3)
A 		65.4
(3)
A 		11.3
(-2.2)
A 		3.3
(-3)
A 		62
C 11.6
(-1.9)
A 		46.8
(3)
A 		12.3
(-1.8)
A 		9.5
(-2.2)
A 		4.1
(-3)
A 		4.9
(-2.9)
A 		43
avr 14.6
(-0.6) 		21.2
(1.3) 		9.5
(-2) 		27.2
(3) 		14.5
(-0.6) 		6.1
(-3) 		21
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 11.4
(3)
A 		7.9
(0.6)
A 		3.4
(-2.4)
A 		2.5
(-3)
A 		9
B 12.5
(3)
A 		1.5
(-3)
A 		2.9
(-2.2)
A 		2
(-2.7)
A 		11
C 2.6
(-3)
A 		2.8
(-2.8)
A 		3.2
(-2.3)
A 		7.4
(3)
A 		5
avr 8.8
(3) 		4.1
(-2) 		3.2
(-3) 		4
(-2.1) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 4.5
(-0.3)
A 		2.8
(-1.8)
A 		1.3
(-3)
A 		1.7
(-2.7)
A 		8.5
(3)
A 		2.4
(-2.1)
A 		7
B 2.7
(-2.4)
A 		3
(-2.3)
A 		2.5
(-2.5)
A 		17.3
(3)
A 		4.6
(-1.7)
A 		1.2
(-3)
A 		16
C 4.3
(-1.6)
A 		14.3
(3)
A 		3.1
(-2.2)
A 		1.9
(-2.7)
A 		1.3
(-3)
A 		1.6
(-2.9)
A 		13
avr 3.8
(-0.6) 		6.7
(2.7) 		2.3
(-2.3) 		7
(3) 		4.8
(0.5) 		1.7
(-3) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192870_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16699
Sequence Type Exemplar sequence
Representative Public ID C36B7.1 NCBI
Target Description C36B7.1 /REP_DB=WormBase Gene ID /WP=CE04172 /GB=AAK68227.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=CDC2-CDC28 subfamily of ser-thr protein kinases
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076798(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076798 NCBI Caenorhabditis elegans C36B7.1 (C36B7.1) mRNA, complete cds. 11/11 None
SNAP00000024839 ENSEMBL cdna:SNAP chromosome:CEL140:X:7112897:7114811:1 11/11 None
GENEFINDER00000024842 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:7112897:7114811:1 11/11 None
C36B7.1 ENSEMBL cdna:known chromosome:CEL140:X:7112837:7114811:1 gene:C36B7.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:7112835-7114810(+) 100.0 100.0
Public Domain and Genome References
Gene Title CDC2/CDC28 subfamily of ser/thr protein kinases
Ensembl C36B7.1
Entrez Gene 183253 Entrez gene
SwissProt Q966P5 EMBL-EBI
WormBase CE04172 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_509199 C36B7.1 [Caenorhabditis elegans] gb|AAK68227.1| Hypothetical protein C36B7.1 [Caenorhabditis elegans] 0.0
blast CAE65844 Hypothetical protein CBG10975 [Caenorhabditis briggsae] 7.0E-64
blast CAE65844 Hypothetical protein CBG10975 [Caenorhabditis briggsae] 6.0E-62
blast NP_509198 C36B7.2 [Caenorhabditis elegans] gb|AAK68228.1| Hypothetical protein C36B7.2 [Caenorhabditis elegans] 1.0E-55
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-16
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 5.0E-19
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-19
hanks 3.1.3 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk3 2.0E-25
hanks 3.1.3 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk3 2.0E-28
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 8.3E-44
Pfam IPR000719 EMBL-EBI Protein kinase 8.3E-44
Pfam IPR000719 EMBL-EBI Protein kinase 2.1E-36
Sequence
Target Sequence 
>C. ELEGANS:192870_AT
tgaaacctgccaatgttcttctcaatgaatggaacagaaacaatttgaagctcactgact
ttggtttatctacatttgtcaaccagggaccatttttccgagactatcaaacgctatact
ataaggcacccgaagttttttgccagggaaaagttagcgtggaaattgacatttggtcat
tgggatgtgtggcagccgaaatcgtacgtggtaccccgctatttgttggagacaactact
ttgatcaatttgctttaattcaagaattttttggtaaaccatcacgaaagttgtttaaca
cttggggaggaattcaccaattttacacggagtacttctttccacgtcattgcttcgaat
ggcttaatccttttaatggagaccgcaccatggaaatcgaaccacattacaaactggcac
atccgtcgagaaagcctcctttgactagctcactggtaagcaagttgccaggaggaaacc
agaaatttttggctagattcctaatgagatgttttgaatgggatccgactgaacgcatca
agtcatcattcatttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGAAACCTGCCAATGTTCTTCTCAA 354 573 770 Antisense
AGCTCACTGACTTTGGTTTATCTAC 702 77 818 Antisense
GTCAACCAGGGACCATTTTTCCGAG 575 461 847 Antisense
GCAGCCGAAATCGTACGTGGTACCC 652 313 961 Antisense
GGTACCCCGCTATTTGTTGGAGACA 353 497 979 Antisense
TTACACGGAGTACTTCTTTCCACGT 449 681 1092 Antisense
TTCCACGTCATTGCTTCGAATGGCT 568 697 1109 Antisense
GGCACATCCGTCGAGAAAGCCTCCT 610 535 1185 Antisense
CTCCTTTGACTAGCTCACTGGTAAG 578 235 1205 Antisense
GAATGGGATCCGACTGAACGCATCA 258 333 1285 Antisense
AACGCATCAAGTCATCATTCATTTT 372 145 1301 Antisense
Sequence Source Affymetrix Proprietary Database