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[192868_at] guanine nucleotide-binding protein

Description K04D7.1 /REP_DB=WormBase Gene ID /WP=CE06090 /TR=SW:Q21215 /GB=CAA93514.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=guanine nucleotide-binding protein
Cluster 6grp_highest_10_10 > 04      6grp_high1_10_10 > 21      4grp_highest_8_8 > 14      4grp_high_8_8 > 22      6grp_highest_nonorm > 19      6grp_total > 41      4grp_total > 17      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 17327
1 2 3 4 range
A 25972.3
(-3)
P 		31221.9
(-1.1)
P 		30611.6
(-1.3)
P 		42424.8
(3)
P 		16453
B 28269.9
(-3)
P 		30467.1
(-1)
P 		32698.9
(1.1)
P 		34747.3
(3)
P 		6477
C 25250.4
(-2.9)
P 		27981.5
(-1.8)
P 		25097.8
(-3)
P 		39617.8
(3)
P 		14520
avr 26497.5
(-3) 		29890.2
(-1.4) 		29469.4
(-1.6) 		38930
(3) 		12433

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 8313
1 2 3 4 5 6 range
A 25550.8
(3)
P 		21957.6
(-1.1)
P 		23351.8
(0.5)
P 		20942.2
(-2.3)
P 		20314.1
(-3)
P 		20629
(-2.6)
P 		5237
B 20829.7
(-0.1)
P 		21730.3
(0.7)
P 		24616.7
(3)
P 		20693.6
(-0.2)
P 		19288.6
(-1.3)
P 		17238.1
(-3)
P 		7379
C 19213.8
(-1.6)
P 		21803.5
(1)
P 		23161.7
(2.4)
P 		23708.6
(3)
P 		19505.2
(-1.3)
P 		17860.5
(-3)
P 		5848
avr 21864.8
(0.8) 		21830.5
(0.8) 		23710.1
(3) 		21781.5
(0.7) 		19702.6
(-1.7) 		18575.9
(-3) 		5134
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3246
1 2 3 4 range
A 9456.5
(3)
P 		6777.4
(-2)
P 		8002.5
(0.3)
P 		6210.2
(-3)
P 		3246
B 9015
(3)
P 		7524.7
(-2.6)
P 		7577.1
(-2.4)
P 		7404.7
(-3)
P 		1610
C 8358.6
(1.9)
P 		8044.8
(1)
P 		8747.4
(3)
P 		6680.2
(-3)
P 		2067
avr 8943.4
(3) 		7449
(-1.1) 		8109
(0.7) 		6765
(-3) 		2178

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3127
1 2 3 4 5 6 range
A 4710.1
(-3)
P 		7809.2
(3)
P 		5085.5
(-2.3)
P 		5311.4
(-1.8)
P 		6129.9
(-0.3)
P 		5022.5
(-2.4)
P 		3099
B 7247.7
(1.5)
P 		7233.1
(1.5)
P 		5977.7
(-1.7)
P 		5481
(-3)
P 		7836.7
(3)
P 		6428
(-0.6)
P 		2356
C 7121.7
(3)
P 		6652.9
(1.8)
P 		5895.1
(-0.1)
P 		4767.8
(-3)
P 		6311.6
(0.9)
P 		5978.9
(0.1)
P 		2354
avr 6359.8
(0.4) 		7231.7
(3) 		5652.8
(-1.6) 		5186.7
(-3) 		6759.4
(1.6) 		5809.8
(-1.2) 		2045
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192868_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8879
Sequence Type Exemplar sequence
Representative Public ID K04D7.1 NCBI
Target Description K04D7.1 /REP_DB=WormBase Gene ID /WP=CE06090 /TR=SW:Q21215 /GB=CAA93514.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=guanine nucleotide-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069458(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069458 NCBI Caenorhabditis elegans K04D7.1 (K04D7.1) mRNA, complete cds. 11/11 None
SNAP00000009540 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10176681:10177801:1 11/11 None
GENEFINDER00000009547 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10176681:10177801:1 11/11 None
K04D7.1.3 ENSEMBL cdna:known chromosome:CEL140:IV:10176456:10177887:1 gene:K04D7.1 11/11 None
K04D7.1.4 ENSEMBL cdna:known chromosome:CEL140:IV:10176651:10178070:1 gene:K04D7.1 11/11 None
K04D7.1.5 ENSEMBL cdna:known chromosome:CEL140:IV:10176651:10178269:1 gene:K04D7.1 11/11 None
K04D7.1.2 ENSEMBL cdna:known chromosome:CEL140:IV:10176651:10177887:1 gene:K04D7.1 11/11 None
K04D7.1.1 ENSEMBL cdna:known chromosome:CEL140:IV:10176654:10177887:1 gene:K04D7.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10176686-10177807(+) 100.0 100.0
Public Domain and Genome References
Gene Title guanine nucleotide-binding protein
Ensembl K04D7.1
Entrez Gene 177895 Entrez gene
SwissProt Q21215 EMBL-EBI
WormBase CE06090 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:258155_AT guanine nucleotide-binding family protein / activated protein kinase C receptor (RACK1) at
CANINE:1598262_S_AT similar to Guanine nucleotide-binding protein beta subunit 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) cfa
CANINE:1592371_S_AT similar to Guanine nucleotide-binding protein beta subunit 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) cfa
CANINE:1592019_AT similar to Guanine nucleotide-binding protein beta subunit 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) cfa
CANINE:1591618_S_AT similar to Guanine nucleotide-binding protein beta subunit 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) cfa
CANINE:1587949_X_AT similar to Guanine nucleotide-binding protein beta subunit 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) cfa
CANINE:1587346_S_AT similar to Guanine nucleotide-binding protein beta subunit 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) cfa
CANINE_2:CFA.3181.1.S1_AT similar to Guanine nucleotide-binding protein beta subunit 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) cfa
DROSOPHILA_2:1626602_AT Receptor of activated protein kinase C 1 dm
DROSGENOME1:143933_AT Receptor of activated protein kinase C 1 dm
CHICKEN:GGA.4181.1.S1_S_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 gga
HG-U133_PLUS_2:200651_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U133A:200651_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-FOCUS:200651_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U133A_2:200651_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HUGENEFL:M24194_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
U133_X3P:G5174446_3P_X_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
U133_X3P:G5174446_3P_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U95AV2:34608_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U95AV2:34609_G_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U95E:73163_F_AT guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
U133_X3P:HS.5662.1.A1_3P_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U133A_2:222034_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U133_PLUS_2:222034_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U133A:222034_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
HG-U95AV2:34610_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 hs
MU11KSUBB:MSA.18100.0_F_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MOE430A:1455168_A_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MOUSE430A_2:1455168_A_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MOUSE430_2:1455168_A_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MU11KSUBB:MSA.1827.0_F_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MU11KSUBB:MSA.17555.0_F_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MU11KSUBB:MSA.30760.0_S_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MU11KSUBB:MSA.30120.0_F_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MU11KSUBB:X75313_F_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MU11KSUBB:MSA.22841.0_S_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MG-U74AV2:99340_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MG-U74BV2:165096_F_AT guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 mm
MU11KSUBB:MSA.30463.0_S_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MOE430B:1440120_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MOUSE430_2:1440120_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MU11KSUBB:MSA.16667.0_F_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MU19KSUBA:TC22529_F_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MU19KSUBB:TC31693_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MU19KSUBB:TC31695_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MU19KSUBC:TC36030_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MU19KSUBC:TC36031_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
MU19KSUBC:TC36032_AT Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 (Gnb2l1), mRNA mm
RN-U34:RC_AI171319_S_AT guanine nucleotide binding protein, beta polypeptide 2-like 1 rn
RG-U34C:RC_AI171319_S_AT guanine nucleotide binding protein, beta polypeptide 2-like 1 rn
RN-U34:U03390_AT guanine nucleotide binding protein, beta polypeptide 2-like 1 rn
RG-U34A:U03390_AT guanine nucleotide binding protein, beta polypeptide 2-like 1 rn
YEAST_2:1771920_AT WD repeat protein (G-beta like protein) involved in translation regulation; required for repression of Gcn4p activity in the absence of amino-acid starvation; core component of the ribosome; ortholog of mammalian RACK1 Sc
Protein Similarities
Method ID Description E-Value
blast CAA93514 Hypothetical protein K04D7.1 [Caenorhabditis elegans] ref|NP_501859.1| K04D7.1 [Caenorhabditis elegans] sp|Q21215|GBLP_CAEEL Guanine nucleotide-binding protein beta subunit 2-like 1.0E-172
blast CAE59917 Hypothetical protein CBG03402 [Caenorhabditis briggsae] 1.0E-169
Protein Domains
Database ID Description E-Value
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.1E-8
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.9E-12
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.4E-11
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.3E-9
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.2E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 5.3E-5
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 4.7E-4
Sequence
Target Sequence 
>C. ELEGANS:192868_AT
tgattgccacaccgattgggtttccaccgttcgtttctctccatcgaaccgcgatccagt
gatcgtctccgcaggatgggacaaggttgtcaaggtctggaacctcggaaactgccgtct
gaagaccaaccacatcggtcacaccggatacgtcaacaccgttaccgtctctccagatgg
ttccctctgtgcttccggaggcaaagacggacaagctatgctttgggacctcaacgaggg
caagcacttgtacacccttccaggaaacgacgtcatcaacgccatgtccttctctccaaa
cagatactggctctgcgccgctgtcggatcttccatcaagatctgggatctcgaggacaa
gaaggagatcgaggagctcaagccagaaatcgccagctctggaagctcaagaggatccag
cccacagtgtatctctttggcctggtctcaagacggacaaaccctcttcgccggatacac
cgataac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGATTGCCACACCGATTGGGTTTCC 643 563 462 Antisense
GAACCGCGATCCAGTGATCGTCTCC 97 347 507 Antisense
GAACCTCGGAAACTGCCGTCTGAAG 480 345 561 Antisense
TCCCTCTGTGCTTCCGGAGGCAAAG 62 597 643 Antisense
CAAGCTATGCTTTGGGACCTCAACG 432 183 673 Antisense
GAGGGCAAGCACTTGTACACCCTTC 643 393 697 Antisense
GAAACGACGTCATCAACGCCATGTC 498 357 725 Antisense
ATGTCCTTCTCTCCAAACAGATACT 380 49 745 Antisense
GGAAGCTCAAGAGGATCCAGCCCAC 317 531 862 Antisense
CACAGTGTATCTCTTTGGCCTGGTC 33 197 884 Antisense
CCTCTTCGCCGGATACACCGATAAC 313 267 924 Antisense
Sequence Source Affymetrix Proprietary Database