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[192846_at] serine protease inhibitor

Description F20D6.3 /REP_DB=WormBase Gene ID /WP=CE07108 /GEN=srp-8 /TR=Q19651 /GB=AAB37049.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=serine protease inhibitor
Cluster 6grp_total > 52      4grp_total > 06      6grp_cgc > 90      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 47
1 2 3 4 range
A 8.5
(-3)
A 		10.4
(-2.5)
A 		16.8
(-1)
A 		33.7
(3)
A 		25
B 50.2
(3)
A 		6.7
(-3)
A 		27.9
(-0.1)
A 		15
(-1.9)
A 		44
C 17.1
(-1.2)
A 		3.7
(-3)
A 		5.1
(-2.8)
A 		49.5
(3)
P 		46
avr 25.3
(1.3) 		6.9
(-3) 		16.6
(-0.7) 		32.7
(3) 		26

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 54
1 2 3 4 5 6 range
A 4.8
(-2.6)
A 		6.8
(-2.4)
A 		30
(0.2)
A 		1.3
(-3)
A 		55.5
(3)
P 		12.4
(-1.8)
A 		54
B 15.2
(-1.3)
A 		31.5
(1)
M 		45.9
(3)
A 		21.2
(-0.4)
A 		3.5
(-2.9)
A 		2.7
(-3)
A 		43
C 22.9
(0.9)
P 		31.8
(3)
A 		16.1
(-0.7)
A 		18.2
(-0.2)
A 		23
(0.9)
A 		6.3
(-3)
A 		26
avr 14.3
(-1.2) 		23.4
(1.1) 		30.7
(3) 		13.6
(-1.3) 		27.3
(2.1) 		7.1
(-3) 		24
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 15
1 2 3 4 range
A 3.1
(-1.2)
A 		2.3
(-3)
A 		4.4
(1.8)
A 		4.9
(3)
A 		3
B 16
(3)
A 		1.7
(-3)
A 		6.5
(-1)
A 		3.2
(-2.4)
A 		14
C 5.7
(0.8)
A 		1.1
(-3)
A 		1.8
(-2.4)
A 		8.3
(3)
P 		7
avr 8.3
(3) 		1.7
(-3) 		4.2
(-0.7) 		5.5
(0.5) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 0.9
(-2.8)
A 		2.4
(-2.2)
A 		6.5
(-0.7)
A 		0.3
(-3)
A 		16.7
(3)
P 		3
(-2)
A 		16
B 5.3
(-0.4)
A 		10.5
(2.6)
M 		11.1
(3)
A 		5.6
(-0.3)
A 		1.4
(-2.8)
A 		1
(-3)
A 		10
C 8.5
(2.1)
P 		9.7
(3)
A 		4.1
(-1.4)
A 		3.7
(-1.7)
A 		7.4
(1.2)
A 		2.1
(-3)
A 		8
avr 4.9
(-0.3) 		7.5
(2.1) 		7.2
(1.8) 		3.2
(-1.9) 		8.5
(3) 		2
(-3) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192846_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11276
Sequence Type Exemplar sequence
Representative Public ID F20D6.3 NCBI
Target Description F20D6.3 /REP_DB=WormBase Gene ID /WP=CE07108 /GEN=srp-8 /TR=Q19651 /GB=AAB37049.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=serine protease inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072707(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072707 NCBI Caenorhabditis elegans SeRPin family member (srp-8) (srp-8) mRNA, complete cds. 11/11 None
GENEFINDER00000033166 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:8186167:8189910:1 11/11 None
F20D6.3 ENSEMBL cdna:known chromosome:CEL140:V:8186909:8188139:1 gene:F20D6.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:8186984-8188140(+) 99.9 99.9
Public Domain and Genome References
Gene Title serine protease inhibitor
Gene Symbol srp-8
Ensembl F20D6.3
Entrez Gene 191960 Entrez gene
SwissProt Q19651 EMBL-EBI
WormBase CE07108 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB37049 Serpin protein 8 [Caenorhabditis elegans] ref|NP_505108.1| SeRPin family member (srp-8) [Caenorhabditis elegans] 0.0
blast AAB37049 Serpin protein 8 [Caenorhabditis elegans] ref|NP_505108.1| SeRPin family member (srp-8) [Caenorhabditis elegans] 1.0E-177
blast AAB37047 Hypothetical protein F20D6.2 [Caenorhabditis elegans] ref|NP_505109.1| F20D6.2 [Caenorhabditis elegans] 1.0E-162
blast CAE66110 Hypothetical protein CBG11330 [Caenorhabditis briggsae] 1.0E-141
blast AAS13534 serine or cysteine protease inhibitor [Caenorhabditis elegans] 1.0E-111
blast AAT81199 Serpin protein 7, isoform c [Caenorhabditis elegans] ref|NP_001023824.1| SeRPin family member (srp-7) [Caenorhabditis elegans] gb|AAS13533.1| serine or cysteine protease inhibitor [Caenorhabditis elegans] 6.0E-83
Protein Domains
Database ID Description E-Value
Pfam IPR000215 EMBL-EBI Serpin 1.8E-7
Pfam IPR000215 EMBL-EBI Serpin 2.6E-21
Pfam IPR002485 EMBL-EBI Protein of unknown function DUF13 6.1E-49
Pfam IPR000215 EMBL-EBI Serpin 6.7E-8
Pfam IPR000215 EMBL-EBI Serpin 1.7E-20
Sequence
Target Sequence 
>C. ELEGANS:192846_AT
gtatttctcagtgctgcatgttttgaagctcaatggcagaacaagttccataaattatct
acttccaaaaaagagtttttctgcacagcaaactcacacagaaacataaaattcttacac
gcaactggtgctaacagaaaatactgtgaaaacgacaaattccaagttcttagtcttcca
tatacagacagttcgtttgaaatgacaatttttcttccaaaagaacaatttggattggct
gaagcattgaaaacactggggacgtctaccattcaagaactgaagtcaaatgtttctaac
tatctagttaatgttcaaattccaatatggcggaatgaaacagagattgatctgaatagc
acacttcaggcgattggaataacaaagatacttaacgagtctgcttatata

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTATTTCTCAGTGCTGCATGTTTTG 593 453 484 Antisense
GAAGCTCAATGGCAGAACAAGTTCC 318 343 508 Antisense
AGTTCCATAAATTATCTACTTCCAA 61 63 527 Antisense
TGCACAGCAAACTCACACAGAAACA 62 577 565 Antisense
ATTCTTACACGCAACTGGTGCTAAC 443 11 594 Antisense
GACAAATTCCAAGTTCTTAGTCTTC 438 365 637 Antisense
CTTCCATATACAGACAGTTCGTTTG 47 219 658 Antisense
AAACACTGGGGACGTCTACCATTCA 324 129 734 Antisense
GGGACGTCTACCATTCAAGAACTGA 404 493 742 Antisense
GAATAGCACACTTCAGGCGATTGGA 246 325 837 Antisense
GATACTTAACGAGTCTGCTTATATA 245 423 870 Antisense
Sequence Source Affymetrix Proprietary Database