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[192843_at] hexaprenyl pyrophosphate synthetase

Description C24A11.9 /REP_DB=WormBase Gene ID /WP=CE08350 /TR=P91093 /GB=AAB37678.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=hexaprenyl pyrophosphate synthetase
Cluster 6grp_highest_10_10 > 02      6grp_high1_10_10 > 10      4grp_highest_8_8 > 34      4grp_high_8_8 > 57      6grp_highest_nonorm > 52      6grp_total > 13      4grp_total > 62      6grp_cgc > 60      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 546
1 2 3 4 range
A 632.7
(3)
P 		390.9
(-0)
P 		452.3
(0.7)
P 		154.4
(-3)
P 		478
B 630.4
(3)
P 		330.1
(-0.8)
P 		502.4
(1.4)
P 		161
(-3)
P 		469
C 700.8
(3)
P 		436.1
(0)
P 		534.4
(1.1)
P 		165.3
(-3)
P 		536
avr 654.6
(3) 		385.7
(-0.3) 		496.4
(1.1) 		160.2
(-3) 		494

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 388
1 2 3 4 5 6 range
A 762.9
(3)
P 		709
(1.6)
P 		601.1
(-1.3)
P 		606
(-1.2)
P 		559.7
(-2.5)
P 		539.3
(-3)
P 		224
B 551.3
(-0.9)
P 		607.1
(0.3)
P 		733.3
(3)
P 		709.1
(2.5)
P 		640.6
(1)
P 		452.5
(-3)
P 		281
C 819.6
(3)
P 		685.5
(0.9)
P 		652.7
(0.4)
P 		749.8
(1.9)
P 		491.5
(-2.1)
P 		431.9
(-3)
P 		388
avr 711.3
(3) 		667.2
(1.9) 		662.4
(1.8) 		688.3
(2.4) 		563.9
(-0.7) 		474.6
(-3) 		237
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 209
1 2 3 4 range
A 230.4
(3)
P 		84.9
(-1.2)
P 		118.2
(-0.2)
P 		22.6
(-3)
P 		208
B 201
(3)
P 		81.5
(-1.3)
P 		116.4
(-0)
P 		34.3
(-3)
P 		167
C 232
(3)
P 		125.4
(-0.1)
P 		186.3
(1.7)
P 		27.9
(-3)
P 		204
avr 221.1
(3) 		97.3
(-0.9) 		140.3
(0.5) 		28.3
(-3) 		193

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 173
1 2 3 4 5 6 range
A 140.6
(-2.5)
P 		252.2
(3)
P 		130.9
(-3)
P 		153.7
(-1.9)
P 		168.9
(-1.1)
P 		131.3
(-3)
P 		121
B 191.8
(-1.5)
P 		202.1
(-0.8)
P 		178.1
(-2.4)
P 		187.8
(-1.7)
P 		260.3
(3)
P 		168.7
(-3)
P 		92
C 303.8
(3)
P 		209.2
(-0.6)
P 		166.1
(-2.2)
P 		150.8
(-2.8)
P 		159
(-2.5)
P 		144.6
(-3)
P 		159
avr 212.1
(2.3) 		221.2
(3) 		158.4
(-2.2) 		164.1
(-1.7) 		196.1
(0.9) 		148.2
(-3) 		73
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192843_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.789
Sequence Type Exemplar sequence
Representative Public ID C24A11.9 NCBI
Target Description C24A11.9 /REP_DB=WormBase Gene ID /WP=CE08350 /TR=P91093 /GB=AAB37678.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=hexaprenyl pyrophosphate synthetase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059187(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059187 NCBI Caenorhabditis elegans COenzyme Q (ubiquinone) biosynthesis family member (coq-1) (coq-1) mRNA, complete cds. 11/11 A 
C24A11.9 ENSEMBL cdna:known chromosome:CEL140:I:5412869:5415632:-1 gene:C24A11.9 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:5413129-5414723(-) 100.0 100.0
Public Domain and Genome References
Gene Title hexaprenyl pyrophosphate synthetase
Gene Symbol coq-1
Ensembl C24A11.9
Entrez Gene 172190 Entrez gene
SwissProt P91093 EMBL-EBI
WormBase CE29183 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:262526_AT geranyl diphosphate synthase, putative / GPPS, putative / dimethylallyltransferase, putative / prenyl transferase, putative at
CANINE_2:CFAAFFX.7413.1.S1_AT similar to trans-prenyltransferase cfa
DROSOPHILA_2:1641558_AT dm
DROSGENOME1:151113_AT dm
DROSGENOME1:150933_AT dm
CHICKEN:GGA.9924.1.S1_AT trans-prenyltransferase gga
HG-U133_PLUS_2:220865_S_AT trans-prenyltransferase hs
HG-U133A:220865_S_AT trans-prenyltransferase hs
HG-FOCUS:220865_S_AT trans-prenyltransferase hs
HG-U133A_2:220865_S_AT trans-prenyltransferase hs
U133_X3P:G11863164_3P_A_AT trans-prenyltransferase hs
HG-U95E:72483_AT trans-prenyltransferase hs
HG-U95E:91048_AT trans-prenyltransferase hs
HG-U133_PLUS_2:236298_AT Trans-prenyltransferase hs
HG-U133B:236298_AT Trans-prenyltransferase hs
HU35KSUBC:RC_H99626_AT Trans-prenyltransferase hs
MOE430A:1431893_A_AT trans-prenyltransferase mm
MOUSE430_2:1431893_A_AT trans-prenyltransferase mm
MOUSE430A_2:1431893_A_AT trans-prenyltransferase mm
MOUSE430_2:1454090_AT trans-prenyltransferase mm
MOE430A:1454090_AT trans-prenyltransferase mm
MOUSE430A_2:1454090_AT trans-prenyltransferase mm
MOE430A:1438506_S_AT Trans-prenyltransferase, mRNA (cDNA clone MGC:28441 IMAGE:4039464) mm
MOUSE430A_2:1438506_S_AT Trans-prenyltransferase, mRNA (cDNA clone MGC:28441 IMAGE:4039464) mm
MOUSE430_2:1438506_S_AT Trans-prenyltransferase, mRNA (cDNA clone MGC:28441 IMAGE:4039464) mm
YEAST_2:1773062_AT Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8299 isoprenoid biosynthesis inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB37678 Coenzyme q (ubiquinone) biosynthesis protein 1 [Caenorhabditis elegans] ref|NP_491588.1| COenzyme Q (ubiquinone) biosynthesis family member (coq-1) [Caenorhabditis elegans] 0.0
blast CAE66926 Hypothetical protein CBG12314 [Caenorhabditis briggsae] 0.0
blast XP_781598 PREDICTED: similar to trans-prenyltransferase [Strongylocentrotus purpuratus] 1.0E-74
Protein Domains
Database ID Description E-Value
Pfam IPR000092 EMBL-EBI Polyprenyl synthetase 1.4E-54
Sequence
Target Sequence 
>C. ELEGANS:192843_AT
ttgctcgtgccacgcagattctttgctccatcggaaaacccaacatcatttcagttatgg
cgtcgattattgaagatttggttttaggtgaatttatgcaaatgtcaacaactccaacag
atgctacaccagtagacagaatgaaggcttatatagaaaaaactcatcgaaaaactgcca
gtttgttcgccagtagttgccggtctgctgctattcttgcagatggatcagatttgaagc
ttcatgaaattgcgttcgagtacggtcgaaatttgggaatcgctttccaacttgctgacg
atcttcttgattttatagcgactgctgatgaaatgggaaaacctgtggccgctgatttga
aattaggtctcgccactgctccggtactatacgcttgcgagcaatatcctgagctcaata
cgatgcttcttcgaaaattcaagcatgatggagatgctgaaaaagcacgggaaattgttg
taaattcggatggaatggataaaacgcgaagattgattgattcatattcacaaaaagctg
ttgaaatggcttcatccctccccaaccgcaatgaatctacgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGCTCGTGCCACGCAGATTCTTTG 477 703 218 Antisense
GATTCTTTGCTCCATCGGAAAACCC 159 431 234 Antisense
CCAGTTTGTTCGCCAGTAGTTGCCG 66 265 395 Antisense
TGGGAATCGCTTTCCAACTTGCTGA 183 555 491 Antisense
AACTTGCTGACGATCTTCTTGATTT 387 139 506 Antisense
AAACCTGTGGCCGCTGATTTGAAAT 253 125 556 Antisense
TTGAAATTAGGTCTCGCCACTGCTC 446 703 574 Antisense
ACGCTTGCGAGCAATATCCTGAGCT 557 91 608 Antisense
CTGAGCTCAATACGATGCTTCTTCG 83 239 626 Antisense
AGCTGTTGAAATGGCTTCATCCCTC 488 81 753 Antisense
CTCCCCAACCGCAATGAATCTACGG 182 235 775 Antisense
Sequence Source Affymetrix Proprietary Database