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[192811_at] potassium channel protein

Description R07A4.1 /REP_DB=WormBase Gene ID /WP=CE18123 /GEN=egl-36 /TR=O62350 /GB=CAA91765.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster 6grp_high1_10_10 > 26      6grp_total > 36      4grp_total > 39      6grp_cgc > 15      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 229
1 2 3 4 range
A 271.8
(3)
P 		75.7
(-3)
A 		85.3
(-2.7)
A 		95.3
(-2.4)
A 		196
B 281.6
(3)
P 		73.5
(-2.4)
A 		52.3
(-3)
A 		210
(1.1)
M 		229
C 258.5
(3)
A 		56.2
(-3)
A 		64.4
(-2.8)
A 		116.9
(-1.2)
P 		202
avr 270.6
(3) 		68.5
(-3) 		67.3
(-3) 		140.7
(-0.8) 		203

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 129
1 2 3 4 5 6 range
A 165.4
(1.7)
P 		182.8
(3)
P 		110.6
(-2.3)
A 		101
(-3)
A 		143.4
(0.1)
M 		153.7
(0.9)
P 		82
B 140.7
(-0.5)
A 		182
(3)
P 		111.9
(-3)
A 		112.9
(-2.9)
M 		125.8
(-1.8)
P 		157.2
(0.9)
P 		70
C 193.7
(3)
A 		107.5
(-1)
P 		138.4
(0.4)
P 		148.8
(0.9)
P 		64.6
(-3)
A 		115.2
(-0.6)
P 		129
avr 166.6
(3) 		157.4
(2) 		120.3
(-2) 		120.9
(-2) 		111.3
(-3) 		142
(0.3) 		55
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 87
1 2 3 4 range
A 99
(3)
P 		16.4
(-2.8)
A 		22.3
(-2.4)
A 		13.9
(-3)
A 		85
B 89.8
(3)
P 		18.2
(-2.5)
A 		12.1
(-3)
A 		44.7
(-0.5)
M 		78
C 85.6
(3)
A 		16.1
(-3)
A 		22.4
(-2.5)
A 		19.7
(-2.7)
P 		70
avr 91.5
(3) 		16.9
(-3) 		18.9
(-2.8) 		26.1
(-2.3) 		75

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 51
1 2 3 4 5 6 range
A 30.5
(-2.1)
P 		65
(3)
P 		24.1
(-3)
A 		25.6
(-2.8)
A 		43.3
(-0.2)
M 		37.4
(-1)
P 		41
B 48.9
(0.9)
A 		60.6
(3)
P 		27.2
(-3)
A 		29.9
(-2.5)
M 		51.1
(1.3)
P 		58.6
(2.6)
P 		33
C 71.8
(3)
A 		32.8
(-1.6)
P 		35.2
(-1.3)
P 		29.9
(-1.9)
P 		20.9
(-3)
A 		38.6
(-0.9)
P 		51
avr 50.4
(2.4) 		52.8
(3) 		28.8
(-2.9) 		28.5
(-3) 		38.4
(-0.6) 		44.9
(1) 		24
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192811_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16798
Sequence Type Exemplar sequence
Representative Public ID R07A4.1 NCBI
Target Description R07A4.1 /REP_DB=WormBase Gene ID /WP=CE18123 /GEN=egl-36 /TR=O62350 /GB=CAA91765.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077394(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077394 NCBI Caenorhabditis elegans EGg Laying defective family member (egl-36) (egl-36) mRNA, complete cds. 11/11 None
GENEFINDER00000024562 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:10739417:10744109:1 11/11 None
SNAP00000024556 ENSEMBL cdna:SNAP chromosome:CEL140:X:10741383:10743539:1 11/11 None
R07A4.1 ENSEMBL cdna:known chromosome:CEL140:X:10734249:10744278:1 gene:R07A4.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10734248-10744109(+) 100.0 100.0
Public Domain and Genome References
Gene Title potassium channel protein
Gene Symbol egl-36
Ensembl R07A4.1
Entrez Gene 181269 Entrez gene
SwissProt O62350 EMBL-EBI
WormBase CE18123 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1638914_AT dm
DROSGENOME1:146083_AT dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8076 voltage-gated potassium channel complex inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
5249 voltage-gated potassium channel activity inferred from electronic annotation QuickGO AmiGO
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92011 Hypothetical protein R07A4.1 [Caenorhabditis elegans] emb|CAA91765.1| Hypothetical protein R07A4.1 [Caenorhabditis elegans] ref|NP_509795.1| EGg Laying defective family member (egl-36) [Caenorhabditis elegans] 0.0
blast AAB95119 voltage-dependent potassium channel alpha subunit [Caenorhabditis elegans] 0.0
blast AAB39267 Shaw potassium channel 1.0E-150
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 8.3E-44
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 5.5E-43
Pfam IPR005821 EMBL-EBI Ion transport protein 8.3E-44
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 5.5E-43
Pfam IPR005821 EMBL-EBI Ion transport protein 8.3E-44
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 5.8E-16
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509795.1 4 201-223,358-380,390-409,421-443
R07A4.1 4 201-223,358-380,390-409,421-443
GENEFINDER00000024562 4 197-219,354-376,386-405,417-439
SNAP00000024556 4 121-143,278-300,310-329,341-363
Sequence
Target Sequence 
>C. ELEGANS:192811_AT
attttttctcattcttggtatcgtcatatttgctgcacttgtgtattatgcagaaaaaat
ggaagccaatccaaacaatcaatttcaatcaataccgcttggactatggtgggcgatatg
cacgatgacaaccgtcggatatggagatatgactccgcatacgtcgtttggaagattagt
tggatcactatgtgcagttatgggagtactcacaattgctttgccagttcctgttatcgt
gtccaatttcgcaatgttctactctcacaaccaggcacgagataaacttccgaaacgtcg
tagaagagtgctacccgtagaacagatccgattacaagctcgacgtcatgcggctgtact
ggagccatccgcttcacagggagggttaggaggagggcaggcaattcgtcgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATTTTTTCTCATTCTTGGTATCGTC 482 15 1098 Antisense
ATGACTCCGCATACGTCGTTTGGAA 115 45 1246 Antisense
GAGTACTCACAATTGCTTTGCCAGT 217 399 1301 Antisense
TTTGCCAGTTCCTGTTATCGTGTCC 65 669 1317 Antisense
ATCGTGTCCAATTTCGCAATGTTCT 409 35 1333 Antisense
TCTACTCTCACAACCAGGCACGAGA 16 615 1355 Antisense
GCTACCCGTAGAACAGATCCGATTA 360 303 1407 Antisense
GATTACAAGCTCGACGTCATGCGGC 581 429 1427 Antisense
ATGCGGCTGTACTGGAGCCATCCGC 70 41 1445 Antisense
CCATCCGCTTCACAGGGAGGGTTAG 435 199 1462 Antisense
AGGAGGAGGGCAGGCAATTCGTCGG 300 57 1485 Antisense
Sequence Source Affymetrix Proprietary Database