[Home] | [Total List]

[192808_at] 3-hydroxyanthranilate 3,4-dioxygenase

Description K06A4.5 /REP_DB=WormBase Gene ID /WP=CE06109 /TR=Q19341 /GB=CAA94787.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=3-hydroxyanthranilate 3,4-dioxygenase
Cluster 6grp_highest_10_10 > 15      6grp_high1_10_10 > 41      4grp_highest_8_8 > 01      4grp_high_8_8 > 53      6grp_highest_nonorm > 61      6grp_total > 31      4grp_total > 58      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 915
1 2 3 4 range
A 339.2
(-0.8)
P 		636.6
(2.2)
P 		721.6
(3)
P 		111.7
(-3)
P 		610
B 322
(-1.3)
P 		978.8
(3)
P 		717.2
(1.3)
P 		63.5
(-3)
P 		915
C 359.8
(-1)
P 		915.6
(3)
P 		809.2
(2.2)
P 		73.3
(-3)
P 		842
avr 340.3
(-1) 		843.7
(3) 		749.3
(2.3) 		82.8
(-3) 		761

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 710
1 2 3 4 5 6 range
A 290.2
(-1)
P 		457.4
(0.4)
P 		764.8
(3)
P 		399.8
(-0.1)
P 		307
(-0.9)
P 		55
(-3)
P 		710
B 425.8
(0.3)
P 		506.4
(1.1)
P 		684.2
(3)
P 		533.2
(1.4)
P 		285.5
(-1.2)
P 		119.5
(-3)
P 		565
C 435.1
(1.4)
P 		545.6
(3)
P 		462.3
(1.8)
P 		450.9
(1.6)
P 		193.7
(-2.2)
P 		135.9
(-3)
P 		410
avr 383.7
(0.2) 		503.1
(1.5) 		637.1
(3) 		461.3
(1) 		262.1
(-1.2) 		103.5
(-3) 		534
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 270
1 2 3 4 range
A 123.5
(0.7)
P 		138.2
(1.2)
P 		188.7
(3)
P 		16.3
(-3)
P 		172
B 102.7
(-0.7)
P 		241.7
(3)
P 		166.2
(1)
P 		13.5
(-3)
P 		228
C 119.1
(-0.6)
P 		263.2
(2.6)
P 		282
(3)
P 		12.4
(-3)
P 		270
avr 115.1
(0) 		214.4
(3) 		212.3
(2.9) 		14.1
(-3) 		200

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 155
1 2 3 4 5 6 range
A 53.5
(-1.4)
P 		162.7
(2.8)
P 		166.6
(3)
P 		101.4
(0.4)
P 		92.6
(0.1)
P 		13.4
(-3)
P 		153
B 148.2
(2)
P 		168.6
(3)
P 		166.2
(2.9)
P 		141.2
(1.7)
P 		116
(0.5)
P 		44.6
(-3)
P 		124
C 161.3
(2.7)
P 		166.5
(3)
P 		117.7
(0.6)
P 		90.7
(-0.8)
P 		62.7
(-2.1)
P 		45.5
(-3)
P 		121
avr 121
(0.9) 		165.9
(3) 		150.2
(2.3) 		111.1
(0.5) 		90.4
(-0.4) 		34.5
(-3) 		131
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192808_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11939
Sequence Type Exemplar sequence
Representative Public ID K06A4.5 NCBI
Target Description K06A4.5 /REP_DB=WormBase Gene ID /WP=CE06109 /TR=Q19341 /GB=CAA94787.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=3-hydroxyanthranilate 3,4-dioxygenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073049(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073049 NCBI Caenorhabditis elegans K06A4.5 (K06A4.5) mRNA, complete cds. 11/11 None
K06A4.5 ENSEMBL cdna:known chromosome:CEL140:V:9508273:9509567:1 gene:K06A4.5 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000010081 2/11 Cross Hyb Matching Probes None
GENEFINDER00000010089 2/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:9508272-9509567(+) 100.0 100.0
Public Domain and Genome References
Gene Title 3-hydroxyanthranilate 3,4-dioxygenase
Ensembl K06A4.5
Entrez Gene 179329 Entrez gene
SwissProt Q19341 EMBL-EBI
WormBase CE06109 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1587326_AT similar to 3-hydroxyanthranilate 3,4-dioxygenase (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (3-hydroxyanthranilate oxygenase) cfa
CANINE_2:CFA.12183.1.A1_AT similar to 3-hydroxyanthranilate 3,4-dioxygenase (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (3-hydroxyanthranilate oxygenase) cfa
CANINE_2:CFAAFFX.4525.1.S1_AT similar to 3-hydroxyanthranilate 3,4-dioxygenase (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (3-hydroxyanthranilate oxygenase) cfa
CHICKEN:GGA.9514.1.S1_AT 3-hydroxyanthranilate 3,4-dioxygenase gga
HG-U133_PLUS_2:205657_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
HG-U133A:205657_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
HG-FOCUS:205657_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
HG-U133A_2:205657_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
HU35KSUBA:Z29481_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
HUGENEFL:Z29481_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
HU35KSUBB:RC_T58032_S_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
U133_X3P:G6912405_3P_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
HG-U95AV2:37166_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
HG-U95B:48794_S_AT 3-hydroxyanthranilate 3,4-dioxygenase hs
MOUSE430_2:1432492_A_AT 3-hydroxyanthranilate 3,4-dioxygenase mm
MOUSE430A_2:1432492_A_AT 3-hydroxyanthranilate 3,4-dioxygenase mm
MOE430A:1432492_A_AT 3-hydroxyanthranilate 3,4-dioxygenase mm
MG-U74BV2:110298_AT 3-hydroxyanthranilate 3,4-dioxygenase mm
MU19KSUBC:TC36621_AT 3-hydroxyanthranilate 3,4-dioxygenase, mRNA (cDNA clone MGC:19090 IMAGE:4196161) mm
RG-U34A:D44494_AT 3-hydroxyanthranilate 3,4-dioxygenase rn
RG-U34A:D28339_S_AT 3-hydroxyanthranilate 3,4-dioxygenase rn
RAE230A:1368794_AT 3-hydroxyanthranilate 3,4-dioxygenase rn
RAT230_2:1368794_AT 3-hydroxyanthranilate 3,4-dioxygenase rn
YEAST_2:1772019_AT 3-hydroxyanthranilic acid dioxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway Sc
Protein Similarities
Method ID Description E-Value
blast CAA94787 Hypothetical protein K06A4.5 [Caenorhabditis elegans] emb|CAA94753.1| Hypothetical protein K06A4.5 [Caenorhabditis elegans] ref|NP_505450.1| K06A4.5 [Caenorhabditis elegans] 1.0E-164
blast CAE72181 Hypothetical protein CBG19288 [Caenorhabditis briggsae] 1.0E-159
blast CAG10196 unnamed protein product [Tetraodon nigroviridis] 5.0E-57
Protein Families
Method ID Description E-Value
ec 3HAO_HUMAN (P46952) 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (3-hydroxyanthranilate oxygenase) 1.0E-122
Protein Domains
Database ID Description E-Value
Pfam IPR010329 EMBL-EBI 3-hydroxyanthranilic acid dioxygenase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192808_AT
ggaaatgttcatgttgccagcaagagtagaacattcacctcaaagattttccaactctat
tggtcttgtcgttgaacgtgaacgaaagaatactgaatttgattgtgttcgatttcttgt
tggttcttccaatatcacactctttgaaagatggttctatttgactgatgttgtcaagga
tttacctccattaatcaaagaattttatggatcgaatgaattcaaaactggtaaaccagg
aaaaggaacatttgcatgcaatgctccatacgaagcaagatggactgatttacccgtacc
tattaatagaaaagaatttatctatgatcatatcagtgaagtgaaaaacggaccagtgag
aatttatggagcacctgagtacaaaactgaagttatgttgctaggagagggatcttatga
tttggaaagtggaactgtagagttgctaatttggttgcaggaaaacacatttgcggtcgt
agaagagagcgggttcacttatgcaatga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAAATGTTCATGTTGCCAGCAAGA 607 525 258 Antisense
ATTCACCTCAAAGATTTTCCAACTC 422 11 290 Antisense
ACTCTATTGGTCTTGTCGTTGAACG 319 99 311 Antisense
GTGTTCGATTTCTTGTTGGTTCTTC 392 485 362 Antisense
TTGGTTCTTCCAATATCACACTCTT 612 707 377 Antisense
GATGGTTCTATTTGACTGATGTTGT 51 409 407 Antisense
GATGTTGTCAAGGATTTACCTCCAT 240 409 424 Antisense
TTGCATGCAATGCTCCATACGAAGC 514 703 509 Antisense
AAGATGGACTGATTTACCCGTACCT 490 153 534 Antisense
AGGAAAACACATTTGCGGTCGTAGA 457 55 716 Antisense
GAGAGCGGGTTCACTTATGCAATGA 236 395 742 Antisense
Sequence Source Affymetrix Proprietary Database