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[192788_at] potassium channel protein

Description T01B4.1 /REP_DB=WormBase Gene ID /WP=CE06336 /GEN=twk-16 /TR=Q22042 /GB=CAA93875.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster 6grp_total > 21      4grp_total > 37      6grp_cgc > 81      6grp_cgc_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 61
1 2 3 4 range
A 29.4
(0.3)
A 		49.6
(3)
A 		5.5
(-3)
A 		9.1
(-2.5)
A 		44
B 65.2
(3)
A 		43.4
(-1)
A 		32.1
(-3)
A 		54.3
(1)
A 		33
C 44.9
(3)
A 		4.2
(-3)
A 		6.7
(-2.6)
A 		28.3
(0.6)
A 		41
avr 46.5
(3) 		32.4
(0.3) 		14.8
(-3) 		30.6
(-0) 		32

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 65
1 2 3 4 5 6 range
A 55.3
(1.6)
A 		41.6
(0.2)
A 		68.5
(3)
P 		24.6
(-1.6)
A 		30.6
(-1)
A 		11.7
(-3)
A 		57
B 26.1
(-0.4)
A 		48.8
(2.1)
P 		44.2
(1.6)
A 		4.4
(-2.9)
A 		56.3
(3)
A 		3.6
(-3)
A 		53
C 15.5
(-1.7)
A 		58.9
(3)
P 		51.8
(2.2)
A 		48.8
(1.9)
A 		3.7
(-3)
A 		31.6
(0)
A 		55
avr 32.3
(-0.4) 		49.8
(2.2) 		54.8
(3) 		25.9
(-1.4) 		30.2
(-0.8) 		15.6
(-3) 		39
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 20
1 2 3 4 range
A 10.7
(2.9)
A 		10.8
(3)
A 		1.4
(-2.9)
A 		1.3
(-3)
A 		10
B 20.8
(3)
A 		10.7
(-1.5)
A 		7.4
(-3)
A 		11.6
(-1.1)
A 		13
C 14.9
(3)
A 		1.2
(-3)
A 		2.3
(-2.5)
A 		4.8
(-1.4)
A 		14
avr 15.5
(3) 		7.6
(-1) 		3.7
(-3) 		5.9
(-1.9) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 22
1 2 3 4 5 6 range
A 10.2
(0.7)
A 		14.8
(3)
A 		14.9
(3)
P 		6.2
(-1.4)
A 		9.2
(0.1)
A 		2.9
(-3)
A 		12
B 9.1
(-0.8)
A 		16.3
(1.2)
P 		10.7
(-0.4)
A 		1.2
(-3)
A 		22.9
(3)
A 		1.4
(-2.9)
A 		22
C 5.7
(-1.4)
A 		18
(3)
P 		13.2
(1.3)
A 		9.8
(0.1)
A 		1.2
(-3)
A 		10.6
(0.4)
A 		17
avr 8.3
(-1.3) 		16.4
(3) 		12.9
(1.2) 		5.7
(-2.6) 		11.1
(0.2) 		5
(-3) 		11
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192788_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17460
Sequence Type Exemplar sequence
Representative Public ID T01B4.1 NCBI
Target Description T01B4.1 /REP_DB=WormBase Gene ID /WP=CE06336 /GEN=twk-16 /TR=Q22042 /GB=CAA93875.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078253(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078253 NCBI Caenorhabditis elegans TWiK family of potassium channels family member (twk-21) (twk-21) mRNA, complete cds. 11/11 None
GENEFINDER00000021937 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:16299672:16304036:1 11/11 None
SNAP00000021932 ENSEMBL cdna:SNAP chromosome:CEL140:X:16301574:16304036:1 9/11 None
T01B4.1 ENSEMBL cdna:known chromosome:CEL140:X:16301457:16304036:1 gene:T01B4.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:16301456-16304036(+) 97.58 100.0
Public Domain and Genome References
Gene Title potassium channel protein
Gene Symbol twk-21
Ensembl T01B4.1
Entrez Gene 192078 Entrez gene
SwissProt Q22042 EMBL-EBI
WormBase CE06336 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5267 potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93875 Hypothetical protein T01B4.1 [Caenorhabditis elegans] ref|NP_510654.1| TWiK family of potassium channels family member (twk-21) [Caenorhabditis elegans] 0.0
blast CAE69981 Hypothetical protein CBG16379 [Caenorhabditis briggsae] 1.0E-139
blast CAE69981 Hypothetical protein CBG16379 [Caenorhabditis briggsae] 1.0E-138
blast CAE69981 Hypothetical protein CBG16379 [Caenorhabditis briggsae] 1.0E-123
blast CAA93876 Hypothetical protein T01B4.2 [Caenorhabditis elegans] ref|NP_510655.1| TWiK family of potassium channels family member (twk-22) [Caenorhabditis elegans] 1.0E-121
blast CAA93876 Hypothetical protein T01B4.2 [Caenorhabditis elegans] ref|NP_510655.1| TWiK family of potassium channels family member (twk-22) [Caenorhabditis elegans] 1.0E-108
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510654.1 6 34-56,131-148,155-172,233-255,262-281,291-309
T01B4.1 6 34-56,131-148,155-172,233-255,262-281,291-309
GENEFINDER00000021937 6 164-186,261-278,285-302,363-385,392-411,421-439
SNAP00000021932 6 2-19,92-109,116-133,194-216,223-242,252-270
Sequence
Target Sequence 
>C. ELEGANS:192788_AT
aaaagaaccagtgcgtggtcctcggattcttcttcaagacttgcttcgcggccctgatct
caagatatctggtggaagacggtcgtcttctgacgcatcatcagtaatcaccgaggctag
cgatgaggataccagacactttaaagtgggccgagcaatcttggcggaggctttcgcgcc
cgatgaaagagcttcaaaccacggtacacaattgaattcttgcactgtatccaatgagca
tgattcttgtcaaatcgaggcaattgtattttcatttcatttcatttctttcattaactt
tcaatttaattacagtagtgacgagagcttggaagaacatcaattggagacctacgacac
gtcaggcactcctccaccatacggggatccgactccgaccaccaacttccaaacacgaga
tgaaacagtaacttcattagccgaaaaaacgccactatcgcttaataagg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAAGAACCAGTGCGTGGTCCTCGG 98 131 1071 Antisense
GGCCCTGATCTCAAGATATCTGGTG 118 543 1120 Antisense
GAAGACGGTCGTCTTCTGACGCATC 239 339 1145 Antisense
GACGCATCATCAGTAATCACCGAGG 336 381 1162 Antisense
TGGGCCGAGCAATCTTGGCGGAGGC 564 553 1217 Antisense
AGGCTTTCGCGCCCGATGAAAGAGC 152 55 1238 Antisense
GAAAGAGCTTCAAACCACGGTACAC 623 359 1255 Antisense
GAATTCTTGCACTGTATCCAATGAG 186 325 1284 Antisense
TTGGAGACCTACGACACGTCAGGCA 193 709 1414 Antisense
ACCACCAACTTCCAAACACGAGATG 590 85 1468 Antisense
AAAACGCCACTATCGCTTAATAAGG 122 131 1516 Antisense
Sequence Source Affymetrix Proprietary Database