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[192787_at] Transthyretin-like family (2 domains)

Description F46B3.3 /REP_DB=WormBase Gene ID /WP=CE18686 /TR=Q9XV15 /GB=CAB04404.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Transthyretin-like family (2 domains)
Cluster 6grp_total > 43      4grp_total > 37      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 63
1 2 3 4 range
A 15.4
(-1.1)
A 		29.8
(3)
A 		8.6
(-3)
A 		9.2
(-2.8)
A 		21
B 42.1
(1.5)
A 		55
(3)
A 		22.4
(-0.7)
A 		2.8
(-3)
A 		52
C 35.7
(0.1)
A 		4.2
(-3)
A 		8.1
(-2.6)
A 		65.9
(3)
A 		62
avr 31.1
(3) 		29.7
(2.5) 		13
(-3) 		26
(1.3) 		18

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 68.8
(3)
A 		36.2
(0.1)
A 		43.6
(0.7)
A 		1.8
(-3)
A 		40
(0.4)
A 		12.3
(-2.1)
A 		67
B 25.2
(1.8)
A 		30.6
(3)
A 		24.9
(1.7)
A 		4.5
(-3)
A 		8.2
(-2.1)
A 		6.1
(-2.6)
A 		26
C 6.5
(-2.9)
A 		5.5
(-3)
A 		78.6
(3)
A 		24.6
(-1.4)
A 		6.9
(-2.9)
A 		38.3
(-0.3)
A 		73
avr 33.5
(0.6) 		24.1
(-0.9) 		49
(3) 		10.3
(-3) 		18.4
(-1.7) 		18.9
(-1.7) 		39
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 5.6
(2)
A 		6.5
(3)
A 		2.2
(-2)
A 		1.3
(-3)
A 		5
B 13.4
(2.9)
A 		13.6
(3)
A 		5.2
(-0.9)
A 		0.6
(-3)
A 		13
C 11.8
(3)
A 		1.2
(-3)
A 		2.8
(-2.1)
A 		11.1
(2.6)
A 		11
avr 10.3
(3) 		7.1
(0.2) 		3.4
(-3) 		4.3
(-2.2) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 20
1 2 3 4 5 6 range
A 12.7
(2.9)
A 		12.9
(3)
A 		9.5
(1.4)
A 		0.5
(-3)
A 		12.1
(2.6)
A 		3
(-1.8)
A 		12
B 8.8
(2.1)
A 		10.2
(3)
A 		6
(0.2)
A 		1.2
(-3)
A 		3.3
(-1.6)
A 		2.3
(-2.3)
A 		9
C 2.4
(-2.8)
A 		1.7
(-3)
A 		20
(3)
A 		4.9
(-2)
A 		2.2
(-2.8)
A 		12.8
(0.6)
A 		18
avr 8
(0.6) 		8.3
(0.8) 		11.8
(3) 		2.2
(-3) 		5.9
(-0.7) 		6
(-0.6) 		10
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192787_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13914
Sequence Type Exemplar sequence
Representative Public ID F46B3.3 NCBI
Target Description F46B3.3 /REP_DB=WormBase Gene ID /WP=CE18686 /TR=Q9XV15 /GB=CAB04404.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Transthyretin-like family (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075574(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075574 NCBI Caenorhabditis elegans F46B3.3 (F46B3.3) mRNA, complete cds. 11/11 None
F46B3.3 ENSEMBL cdna:known chromosome:CEL140:V:20601417:20604444:1 gene:F46B3.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000039757 2/11 Cross Hyb Matching Probes None
GENEFINDER00000039775 5/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:20601416-20604444(+) 100.0 100.0
Public Domain and Genome References
Gene Title Transthyretin-like family (2 domains)
Ensembl F46B3.3
Entrez Gene 185831 Entrez gene
SwissProt Q9XV15 EMBL-EBI
WormBase CE18686 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4190 aspartic-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04404 Hypothetical protein F46B3.3 [Caenorhabditis elegans] ref|NP_507975.1| F46B3.3 [Caenorhabditis elegans] 1.0E-163
blast CAA92798 Hypothetical protein C33A12.15 [Caenorhabditis elegans] ref|NP_501683.2| C33A12.15 [Caenorhabditis elegans] 1.0E-24
blast CAE57118 Hypothetical protein CBG25028 [Caenorhabditis briggsae] 5.0E-21
Protein Domains
Database ID Description E-Value
Pfam IPR001534 EMBL-EBI Transthyretin-like 2.4E-19
Pfam IPR001534 EMBL-EBI Transthyretin-like 6.5E-14
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_507975.1 1 5-24
F46B3.3 1 5-24
Sequence
Target Sequence 
>C. ELEGANS:192787_AT
actatgatgtcaccacttctgtacgcgtattttgtgaactattgtaagccatcgttcaac
tggctccgagtaaagtgtggtaactccgtcaaagtttatatcccagccgagtatattgct
gatggacatattcctaaacgcaccttcgacctccacgaaactgaagtttcaacggcttac
actgtcaaactcggccttgaacaagtcataatttgcttcatgattcttctcatcaagctc
gccaccgctgacacgggagccgcccacgttcgtggacaacttttgtgccatggaaaacca
tatgcagcgttgccggataccttggttgcttatggagagactgataaaaacggatacttt
tccttggaaggatcaatctctgaaacgattgtgtcaccaattctgtacgcgtactttgtc
aactattgtgagccatcgttcagtatttttggagtagtttgtggtaactccgtcaaagtt
tttcttcccaaccagtttatcactgagggacatcttcctcaacacgtgttcaaccttcac
gaaacggaagtttccacggctacaacagat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACTATGATGTCACCACTTCTGTACG 569 101 232 Antisense
CCGTCAAAGTTTATATCCCAGCCGA 592 257 317 Antisense
ACATATTCCTAAACGCACCTTCGAC 702 103 357 Antisense
GGCTTACACTGTCAAACTCGGCCTT 187 537 405 Antisense
TCATGATTCTTCTCATCAAGCTCGC 70 623 449 Antisense
GTTGCCGGATACCTTGGTTGCTTAT 115 441 540 Antisense
TTGTGTCACCAATTCTGTACGCGTA 64 707 620 Antisense
CTGTACGCGTACTTTGTCAACTATT 607 239 634 Antisense
TTTTCTTCCCAACCAGTTTATCACT 601 675 711 Antisense
TTCCTCAACACGTGTTCAACCTTCA 568 675 746 Antisense
GGAAGTTTCCACGGCTACAACAGAT 105 527 777 Antisense
Sequence Source Affymetrix Proprietary Database