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[192768_at] serine protease inhibitor

Description C05E4.3 /REP_DB=WormBase Gene ID /WP=CE07937 /GEN=srp-1 /TR=O17362 /GB=AAB71272.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=serine protease inhibitor
Cluster 6grp_total > 96      4grp_total > 02      6grp_cgc > 68      6grp_cgc_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 366
1 2 3 4 range
A 32.7
(-2.7)
A 		88.5
(-1.2)
A 		20.6
(-3)
A 		248.9
(3)
A 		228
B 49.6
(-2.4)
A 		14.1
(-3)
A 		29
(-2.8)
A 		380.3
(3)
A 		366
C 17.8
(-2.9)
A 		13.9
(-3)
A 		17.9
(-2.9)
A 		325.8
(3)
A 		312
avr 33.4
(-2.8) 		38.8
(-2.7) 		22.5
(-3) 		318.3
(3) 		296

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 605
1 2 3 4 5 6 range
A 157.9
(-2.9)
A 		152.6
(-3)
A 		223.8
(-2.2)
A 		386.2
(-0.4)
P 		513.3
(1)
P 		688.7
(3)
P 		536
B 83.4
(-3)
A 		146
(-2.2)
A 		258
(-0.8)
A 		327.4
(0)
M 		461.2
(1.7)
P 		570.3
(3)
P 		487
C 118.8
(-3)
A 		149.3
(-2.6)
A 		269.5
(-1.3)
A 		256.6
(-1.4)
A 		508.6
(1.5)
P 		635.9
(3)
P 		517
avr 120
(-3) 		149.3
(-2.7) 		250.4
(-1.5) 		323.4
(-0.6) 		494.4
(1.4) 		631.6
(3) 		512
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 78
1 2 3 4 range
A 11.9
(-1.7)
A 		19.2
(-0.3)
A 		5.4
(-3)
A 		36.4
(3)
A 		31
B 15.8
(-2)
A 		3.5
(-3)
A 		6.7
(-2.8)
A 		81
(3)
A 		78
C 5.9
(-2.8)
A 		4
(-3)
A 		6.2
(-2.7)
A 		54.9
(3)
A 		51
avr 11.2
(-2.4) 		8.9
(-2.7) 		6.1
(-3) 		57.4
(3) 		51

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 184
1 2 3 4 5 6 range
A 29.1
(-3)
A 		54.3
(-1.9)
A 		48.7
(-2.2)
A 		98
(-0)
P 		154.9
(2.4)
P 		167.7
(3)
P 		139
B 29
(-3)
A 		48.6
(-2.4)
A 		62.6
(-1.9)
A 		86.7
(-1.1)
M 		187.4
(2.2)
P 		212.6
(3)
P 		184
C 44
(-3)
A 		45.5
(-2.9)
A 		68.6
(-2.1)
A 		51.6
(-2.7)
A 		164.6
(1.3)
P 		212.9
(3)
P 		169
avr 34
(-3) 		49.5
(-2.4) 		60
(-2) 		78.8
(-1.4) 		169
(1.9) 		197.7
(3) 		164
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192768_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15641
Sequence Type Exemplar sequence
Representative Public ID C05E4.3 NCBI
Target Description C05E4.3 /REP_DB=WormBase Gene ID /WP=CE07937 /GEN=srp-1 /TR=O17362 /GB=AAB71272.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=serine protease inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070914(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070914 NCBI Caenorhabditis elegans SeRPin family member (srp-1) (srp-1) mRNA, complete cds. 11/11 None
SNAP00000009765 ENSEMBL cdna:SNAP chromosome:CEL140:V:753188:754813:1 11/11 None
GENEFINDER00000009775 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:753188:754813:1 11/11 None
C05E4.3 ENSEMBL cdna:known chromosome:CEL140:V:753170:754844:1 gene:C05E4.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:753187-754813(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine protease inhibitor
Gene Symbol srp-1
Ensembl C05E4.3
Entrez Gene 178585 Entrez gene
SwissProt O17362 EMBL-EBI
WormBase CE07937 Wormbase
Functional Annotations
Ortholog
ID Title Organism
MOE430A:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9f mm
MOUSE430A_2:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9f mm
MOUSE430_2:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9f mm
MU11KSUBA:AA408344_RC_AT serine (or cysteine) peptidase inhibitor, clade B, member 9f mm
MU11KSUBA:AA408234_RC_G_AT serine (or cysteine) peptidase inhibitor, clade B, member 9f mm
MG-U74AV2:161115_R_AT serine (or cysteine) peptidase inhibitor, clade B, member 9f mm
MOE430A:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9e mm
MOUSE430A_2:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9e mm
MOUSE430_2:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9e mm
MU11KSUBA:AA408344_RC_AT serine (or cysteine) peptidase inhibitor, clade B, member 9e mm
MU11KSUBA:AA408234_RC_G_AT serine (or cysteine) peptidase inhibitor, clade B, member 9e mm
MG-U74AV2:161115_R_AT serine (or cysteine) peptidase inhibitor, clade B, member 9e mm
MG-U74AV2:160972_AT serine (or cysteine) peptidase inhibitor, clade B, member 9e mm
MU19KSUBC:TC41616_AT serine (or cysteine) peptidase inhibitor, clade B, member 9e mm
MOUSE430_2:1457200_AT serine (or cysteine) peptidase inhibitor, clade B, member 9d mm
MOE430B:1457200_AT serine (or cysteine) peptidase inhibitor, clade B, member 9d mm
MOE430A:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MOUSE430A_2:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MOUSE430_2:1418423_S_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MU11KSUBA:AA408234_RC_G_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MU11KSUBA:AA408234_RC_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MG-U74AV2:161115_R_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MOE430A:1418422_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MOUSE430A_2:1418422_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MOUSE430_2:1418422_AT serine (or cysteine) peptidase inhibitor, clade B, member 9g mm
MOE430A:1418423_S_AT similar to OTTMUSP00000000641 mm
MOUSE430A_2:1418423_S_AT similar to OTTMUSP00000000641 mm
MOUSE430_2:1418423_S_AT similar to OTTMUSP00000000641 mm
MU11KSUBA:AA408344_RC_AT similar to OTTMUSP00000000641 mm
MU11KSUBA:AA408234_RC_G_AT similar to OTTMUSP00000000641 mm
MG-U74AV2:161115_R_AT similar to OTTMUSP00000000641 mm
MG-U74BV2:164985_I_AT Serine (or cysteine) peptidase inhibitor, clade B, member 9g (Serpinb9g), mRNA mm
MU19KSUBC:TC41547_AT NK26 (Serpinb9e) mm
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB71272 Serpin protein 1 [Caenorhabditis elegans] ref|NP_503315.1| SeRPin family member (srp-1) [Caenorhabditis elegans] gb|AAS13527.1| serine or cysteine protease inhibitor [Caenorhabditis elegans] 0.0
blast CAE62274 Hypothetical protein CBG06333 [Caenorhabditis briggsae] 1.0E-130
blast CAE62292 Hypothetical protein CBG06352 [Caenorhabditis briggsae] 1.0E-69
Protein Domains
Database ID Description E-Value
Pfam IPR000215 EMBL-EBI Serpin 3.3E-70
Sequence
Target Sequence 
>C. ELEGANS:192768_AT
caacttctctatttctgctactgaaaatcgccttgtcccaatgctccgcgagaccagaga
ctacttttataacaaggatgatgagtggcaggttattggtatcccattcaaagacaaatc
cgcatggtttgccattttcctcccaacgcgaagattcgccttggctgaaaatctgaaatc
cctgaacgctgcgaaattccataatcttatcaacaatgtctatcaagagtacatcttttt
gactttccccaaatttaagatggactataagataaatctgaaaaccgccctcgccaagtt
cgggctcgcggagctgttcacagaacaggctgatctttctggaatcgggccggggcttca
gctggcgtcggctacacatcaggcactgattgaggtagatcaagtcggaacccgagccgc
tgctgccaccgaagccaagatcttcttcacctccgccagcagcgatgaacctcttcacat
tcgtgtcgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAACTTCTCTATTTCTGCTACTGAA 57 189 561 Antisense
TCTGCTACTGAAAATCGCCTTGTCC 432 607 574 Antisense
ATGCTCCGCGAGACCAGAGACTACT 437 41 601 Antisense
GTGGCAGGTTATTGGTATCCCATTC 214 491 645 Antisense
TTTCCTCCCAACGCGAAGATTCGCC 566 667 696 Antisense
TCTGAAATCCCTGAACGCTGCGAAA 693 605 732 Antisense
TACATCTTTTTGACTTTCCCCAAAT 501 643 790 Antisense
AGGCTGATCTTTCTGGAATCGGGCC 432 53 887 Antisense
AGATCAAGTCGGAACCCGAGCCGCT 641 65 957 Antisense
CCGAAGCCAAGATCTTCTTCACCTC 367 263 989 Antisense
TGAACCTCTTCACATTCGTGTCGAT 263 573 1026 Antisense
Sequence Source Affymetrix Proprietary Database