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[192752_at] barrier-to-autointegration factor /// ---

Description B0464.7 /REP_DB=WormBase Gene ID /WP=CE26704 /TR=SW:Q03565 /GB=CAA79543.2 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=barrier-to-autointegration factor
Cluster 6grp_highest_10_10 > 74      6grp_high1_10_10 > 47      4grp_highest_8_8 > 17      4grp_high_8_8 > 61      6grp_highest_nonorm > 76      6grp_total > 47      4grp_total > 59      6grp_highest_sub > Cu      6grp_cgc > 36      6grp_high1_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 898
1 2 3 4 range
A 1087.3
(-0.2)
P 		1262.9
(1.4)
P 		1453
(3)
P 		757.3
(-3)
P 		696
B 1194
(-0.8)
P 		1381
(0.7)
P 		1654.8
(3)
P 		926.4
(-3)
P 		728
C 1201
(1)
P 		1368.6
(2.7)
P 		1396.1
(3)
P 		816.3
(-3)
P 		580
avr 1160.8
(-0.1) 		1337.5
(1.5) 		1501.3
(3) 		833.3
(-3) 		668

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 497
1 2 3 4 5 6 range
A 1280.8
(3)
P 		1102.6
(-1.6)
P 		1125.3
(-1)
P 		1205.9
(1.1)
P 		1048.6
(-3)
P 		1253.9
(2.3)
P 		232
B 1134.1
(0.1)
P 		1171.3
(0.8)
P 		1299
(3)
P 		952.3
(-3)
P 		1060.1
(-1.1)
P 		1280.3
(2.7)
P 		347
C 1436.3
(2.8)
P 		1084.4
(-1.4)
P 		1037.9
(-2)
P 		1213.1
(0.1)
P 		953.9
(-3)
P 		1449.5
(3)
P 		496
avr 1283.7
(2.1) 		1119.4
(-1.1) 		1154.1
(-0.4) 		1123.8
(-1) 		1020.9
(-3) 		1327.9
(3) 		307
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 376
1 2 3 4 range
A 395.9
(3)
P 		274.1
(0.4)
P 		379.8
(2.7)
P 		110.9
(-3)
P 		285
B 380.8
(2.9)
P 		341.1
(1.6)
P 		383.5
(3)
P 		197.4
(-3)
P 		186
C 397.6
(1.5)
P 		393.5
(1.4)
P 		486.6
(3)
P 		137.6
(-3)
P 		349
avr 391.4
(2.4) 		336.2
(1.2) 		416.6
(3) 		148.6
(-3) 		268

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 296
1 2 3 4 5 6 range
A 236.1
(-3)
P 		392.1
(3)
P 		245.1
(-2.7)
P 		305.8
(-0.3)
P 		316.4
(0.1)
P 		305.3
(-0.3)
P 		156
B 394.6
(0.8)
P 		389.9
(0.7)
P 		315.4
(-1.3)
P 		252.2
(-3)
P 		430.7
(1.8)
P 		477.4
(3)
P 		225
C 532.4
(3)
P 		330.9
(-1.2)
P 		264.2
(-2.6)
P 		244
(-3)
P 		308.7
(-1.7)
P 		485.2
(2)
P 		288
avr 387.7
(1.7) 		371
(1) 		274.9
(-2.7) 		267.3
(-3) 		351.9
(0.3) 		422.6
(3) 		155
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192752_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6466
Sequence Type Exemplar sequence
Representative Public ID B0464.7 NCBI
Target Description B0464.7 /REP_DB=WormBase Gene ID /WP=CE26704 /TR=SW:Q03565 /GB=CAA79543.2 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=barrier-to-autointegration factor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066684, NM_066683
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
SNAP00000014945 ENSEMBL cdna:SNAP chromosome:CEL140:III:9465669:9466958:1 None
GENEFINDER00000014958 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:9465669:9466958:1 None
SNAP00000014946 ENSEMBL cdna:SNAP chromosome:CEL140:III:9467365:9467689:1 None
GENEFINDER00000014953 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:9467365:9467689:1 None
B0464.9 ENSEMBL cdna:known chromosome:CEL140:III:9465669:9466958:1 gene:B0464.9 None
B0464.7.1 ENSEMBL cdna:known chromosome:CEL140:III:9467353:9467962:1 gene:B0464.7 None
B0464.7.2 ENSEMBL cdna:known chromosome:CEL140:III:9467365:9468014:1 gene:B0464.7 None
NM_066683 NCBI Caenorhabditis elegans B0464.9 (B0464.9) mRNA, complete cds. None
NM_066684 NCBI Caenorhabditis elegans Barrier to Autointegration Factor family member (baf-1) (baf-1) mRNA, complete cds. None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:9465664-9467685(+) 100.0 100.0
Public Domain and Genome References
Gene Title barrier-to-autointegration factor

Gene Symbol baf-1
Ensembl B0464.9
B0464.7
Entrez Gene 176330 Entrez gene
181999 Entrez gene
SwissProt Q03565 EMBL-EBI
Q9BIB3 EMBL-EBI
WormBase CE26704 Wormbase
CE26705 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:255010_AT hydrolase, alpha/beta fold family protein at
CANINE:1600375_X_AT similar to barrier to autointegration factor 1 cfa
CANINE_2:CFA.12468.1.S1_AT similar to barrier to autointegration factor 1 cfa
CANINE_2:CFA.17985.1.S1_S_AT similar to barrier to autointegration factor 1 cfa
CANINE_2:CFAAFFX.144.1.S1_S_AT similar to barrier to autointegration factor 1 cfa
CANINE:1591576_AT similar to protein phosphatase methylesterase 1 cfa
CANINE_2:CFA.7376.1.A1_AT similar to protein phosphatase methylesterase 1 cfa
CANINE_2:CFAAFFX.9257.1.S1_AT similar to protein phosphatase methylesterase 1 cfa
DROSOPHILA_2:1628610_AT dm
DROSGENOME1:146004_AT dm
DROSOPHILA_2:1637946_AT dm
DROSGENOME1:141321_AT dm
CHICKEN:GGAAFFX.11097.2.S1_AT similar to protein phosphatase methylesterase-1 gga
CHICKEN:GGAAFFX.13217.1.S1_S_AT similar to protein phosphatase methylesterase-1 gga
CHICKEN:GGAAFFX.21545.1.S1_S_AT similar to protein phosphatase methylesterase-1 gga
HG-U133A_2:210125_S_AT barrier to autointegration factor 1 hs
HG-U133_PLUS_2:210125_S_AT barrier to autointegration factor 1 hs
HG-FOCUS:210125_S_AT barrier to autointegration factor 1 hs
HG-U133A:210125_S_AT barrier to autointegration factor 1 hs
HU35KSUBA:D31446_AT barrier to autointegration factor 1 hs
HU35KSUBD:RC_AA609713_AT barrier to autointegration factor 1 hs
U133_X3P:G3002950_3P_S_AT barrier to autointegration factor 1 hs
HG-U95AV2:38663_AT barrier to autointegration factor 1 hs
HG-U95B:51021_AT barrier to autointegration factor 1 hs
HG-U133A:217841_S_AT protein phosphatase methylesterase-1 hs
HG-U133_PLUS_2:217841_S_AT protein phosphatase methylesterase-1 hs
HG-U133A_2:217841_S_AT protein phosphatase methylesterase-1 hs
HU35KSUBA:H12112_AT protein phosphatase methylesterase-1 hs
HU35KSUBC:RC_AA479103_AT protein phosphatase methylesterase-1 hs
HU35KSUBD:RC_AA609009_AT protein phosphatase methylesterase-1 hs
U133_X3P:G7706644_3P_S_AT protein phosphatase methylesterase-1 hs
U133_X3P:G7706644_3P_A_AT protein phosphatase methylesterase-1 hs
HG-U133A_2:49077_AT protein phosphatase methylesterase-1 hs
HG-FOCUS:49077_AT protein phosphatase methylesterase-1 hs
HG-U133_PLUS_2:49077_AT protein phosphatase methylesterase-1 hs
HG-U133A:49077_AT protein phosphatase methylesterase-1 hs
HG-U95C:49077_AT protein phosphatase methylesterase-1 hs
HG-U133_PLUS_2:224094_AT Protein phosphatase methylesterase-1 hs
HG-U133B:224094_AT Protein phosphatase methylesterase-1 hs
HU35KSUBB:RC_T95088_AT Protein phosphatase methylesterase-1 hs
U133_X3P:G6650789_3P_AT Protein phosphatase methylesterase-1 hs
U133_X3P:HS.17505.0.A1_3P_AT Protein phosphatase methylesterase-1 hs
HG-U133_PLUS_2:243443_AT Protein phosphatase methylesterase-1 hs
HG-U133B:243443_AT Protein phosphatase methylesterase-1 hs
HG-U95B:47715_AT Protein phosphatase methylesterase-1 hs
MOUSE430_2:1421083_X_AT barrier to autointegration factor 1 mm
MOE430A:1421083_X_AT barrier to autointegration factor 1 mm
MOUSE430A_2:1421083_X_AT barrier to autointegration factor 1 mm
MOUSE430_2:1421081_A_AT barrier to autointegration factor 1 mm
MOE430A:1421081_A_AT barrier to autointegration factor 1 mm
MOUSE430A_2:1421081_A_AT barrier to autointegration factor 1 mm
MOUSE430_2:1421082_S_AT barrier to autointegration factor 1 mm
MOE430A:1421082_S_AT barrier to autointegration factor 1 mm
MOUSE430A_2:1421082_S_AT barrier to autointegration factor 1 mm
MU11KSUBA:C79046_RC_S_AT barrier to autointegration factor 1 mm
MG-U74AV2:101105_AT barrier to autointegration factor 1 mm
MU19KSUBA:TC22629_AT Barrier to autointegration factor 1, mRNA (cDNA clone MGC:5684 IMAGE:3599828) mm
MU19KSUBA:TC22629_G_AT Barrier to autointegration factor 1, mRNA (cDNA clone MGC:5684 IMAGE:3599828) mm
MG-U74BV2:111912_AT RIKEN cDNA 2700017M01 gene mm
MOE430A:1423810_AT RIKEN cDNA 2700017M01 gene mm
MOUSE430A_2:1423810_AT RIKEN cDNA 2700017M01 gene mm
MOUSE430_2:1423810_AT RIKEN cDNA 2700017M01 gene mm
MG-U74CV2:130405_AT RIKEN cDNA 2700017M01 gene, mRNA (cDNA clone MGC:37135 IMAGE:4952806) mm
MOUSE430_2:1445792_AT RIKEN cDNA 2700017M01 gene, mRNA (cDNA clone MGC:37135 IMAGE:4952806) mm
MOE430B:1445792_AT RIKEN cDNA 2700017M01 gene, mRNA (cDNA clone MGC:37135 IMAGE:4952806) mm
MU19KSUBC:TC40082_AT RIKEN cDNA 2700017M01 gene, mRNA (cDNA clone MGC:37135 IMAGE:4952806) mm
MU19KSUBC:TC40082_G_AT RIKEN cDNA 2700017M01 gene, mRNA (cDNA clone MGC:37135 IMAGE:4952806) mm
MU19KSUBC:TC42101_AT RIKEN cDNA 2700017M01 gene, mRNA (cDNA clone MGC:37135 IMAGE:4952806) mm
RG-U34C:AA848386_AT barrier to autointegration factor 1 rn
RAE230A:1367820_AT barrier to autointegration factor 1 rn
RAT230_2:1367820_AT barrier to autointegration factor 1 rn
RG-U34B:RC_AA943785_G_AT similar to Protein phosphatase methylesterase 1 (predicted) rn
RG-U34B:RC_AA943785_AT similar to Protein phosphatase methylesterase 1 (predicted) rn
RG-U34B:RC_AI029827_AT similar to Protein phosphatase methylesterase 1 (predicted) rn
RAE230A:1373844_AT similar to Protein phosphatase methylesterase 1 (predicted) rn
RAT230_2:1373844_AT similar to Protein phosphatase methylesterase 1 (predicted) rn
RAE230A:1386295_AT Similar to Protein phosphatase methylesterase 1 (predicted) rn
RAT230_2:1386295_AT Similar to Protein phosphatase methylesterase 1 (predicted) rn
RG-U34A:RC_AI639051_AT Similar to Protein phosphatase methylesterase 1 (predicted) rn
YEAST_2:1778501_AT Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6725 aromatic compound metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
3690 double-stranded DNA binding inferred from sequence similarity QuickGO AmiGO
42802 protein self binding inferred from sequence similarity QuickGO AmiGO
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
16787 hydrolase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAC35809 Hypothetical protein B0464.9 [Caenorhabditis elegans] ref|NP_499084.1| B0464.9 [Caenorhabditis elegans] sp|Q9BIB3|YKD9_CAEEL Hypothetical protein B0464.9 in chromosome III 0.0
blast CAE65210 Hypothetical protein CBG10085 [Caenorhabditis briggsae] 1.0E-163
blast G88555 protein B0464.7 [imported] - Caenorhabditis elegans 1.0E-115
Protein Domains
Database ID Description E-Value
Pfam IPR004122 EMBL-EBI Barrier to autointegration factor, BAF 1.2E-86
Sequence
Target Sequence 
>C. ELEGANS:192752_AT
aaaagtcgctgcactcattgtcattgatgttgtcgaaggttccgctatggaagcacttgg
aggaatgcgggcgttgatcggctggacagggatctcacaattggtcaaatgcagggaaag
tttcagacttgtgtgttaccaaaagttggacattgtgttcaggaagatagcccacaaaat
cttgcagatgaagtcggaagattcgcttgccgccatagaattgcccaaccgaaattctca
gcccttgcatcaccaccagatccagcgattctcgaatacagaaaacgtcatcaccaataa
ttgctcattttgttttccaatattttcacaacatttctatacaaaaaccatgtcgacttc
tgttaagcatcgtgagttcgtcggagagccaatgggcgacaaagaagtcacatgcatcgc
cgggatcgggccaacatatggcaccaagctcaccgatgcaggcttcgataaagcctacgt
actgttcggacagtatctccttctgaag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAAGTCGCTGCACTCATTGTCATT 167 133 555 Antisense
GATGTTGTCGAAGGTTCCGCTATGG 396 409 580 Antisense
TCGGCTGGACAGGGATCTCACAATT 310 607 632 Antisense
AAGTCGGAAGATTCGCTTGCCGCCA 586 157 745 Antisense
CACCAGATCCAGCGATTCTCGAATA 517 201 808 Antisense
ACCATGTCGACTTCTGTTAAGCATC 161 85 901 Antisense
GCATCGTGAGTTCGTCGGAGAGCCA 297 309 921 Antisense
CGCCGGGATCGGGCCAACATATGGC 72 257 972 Antisense
CAAGCTCACCGATGCAGGCTTCGAT 66 185 999 Antisense
TAAAGCCTACGTACTGTTCGGACAG 326 637 1023 Antisense
GTTCGGACAGTATCTCCTTCTGAAG 499 441 1038 Antisense
Sequence Source Affymetrix Proprietary Database