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[192738_at] unc-7 membrane protein

Description R07D5.1 /REP_DB=WormBase Gene ID /WP=CE06279 /GEN=unc-7 /TR=SW:Q03412 /GB=CAA94607.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=unc-7 membrane protein
Cluster 6grp_total > 15      4grp_total > 45      6grp_cgc > 22      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 169
1 2 3 4 range
A 170.3
(2.7)
M 		175.4
(3)
A 		54.2
(-3)
A 		104.2
(-0.5)
P 		121
B 197.7
(3)
M 		124.4
(-0.6)
A 		114.6
(-1.1)
A 		74.9
(-3)
A 		123
C 223.6
(3)
P 		130.6
(-0.3)
A 		55.2
(-3)
A 		114.8
(-0.9)
P 		168
avr 197.2
(3) 		143.5
(0.4) 		74.7
(-3) 		98
(-1.9) 		123

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 136
1 2 3 4 5 6 range
A 155
(3)
A 		103.9
(0.5)
A 		88
(-0.3)
A 		34.5
(-3)
A 		51.3
(-2.2)
A 		53.7
(-2)
A 		121
B 170.2
(3)
A 		107.3
(0.2)
A 		82.8
(-0.9)
A 		54.7
(-2.1)
A 		58
(-2)
A 		34.8
(-3)
A 		135
C 76.7
(-0.6)
A 		113.8
(3)
A 		56.7
(-2.6)
A 		52.6
(-3)
A 		54.2
(-2.8)
A 		65.7
(-1.7)
A 		61
avr 134
(3) 		108.3
(1.2) 		75.8
(-1) 		47.3
(-3) 		54.5
(-2.5) 		51.4
(-2.7) 		87
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 60
1 2 3 4 range
A 62
(3)
M 		38.1
(0)
A 		14.2
(-3)
A 		15.3
(-2.9)
P 		48
B 63
(3)
M 		30.7
(-1.1)
A 		26.6
(-1.6)
A 		16
(-3)
A 		47
C 74
(3)
P 		37.6
(-1)
A 		19.2
(-3)
A 		19.4
(-3)
P 		55
avr 66.3
(3) 		35.5
(-0.7) 		20
(-2.6) 		16.9
(-3) 		49

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 51
1 2 3 4 5 6 range
A 28.6
(1.2)
A 		36.9
(3)
A 		19.2
(-0.8)
A 		8.7
(-3)
A 		15.5
(-1.6)
A 		13.1
(-2.1)
A 		28
B 59.2
(3)
A 		35.7
(-0.1)
A 		20.1
(-2.1)
A 		14.5
(-2.8)
A 		23.6
(-1.6)
A 		13
(-3)
A 		46
C 28.4
(1.4)
A 		34.7
(3)
A 		14.4
(-2.1)
A 		10.6
(-3)
A 		17.5
(-1.3)
A 		22
(-0.2)
A 		24
avr 38.7
(3) 		35.8
(2.4) 		17.9
(-1.6) 		11.3
(-3) 		18.9
(-1.3) 		16
(-2) 		27
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192738_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17859
Sequence Type Exemplar sequence
Representative Public ID R07D5.1 NCBI
Target Description R07D5.1 /REP_DB=WormBase Gene ID /WP=CE06279 /GEN=unc-7 /TR=SW:Q03412 /GB=CAA94607.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=unc-7 membrane protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078114(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078114 NCBI Caenorhabditis elegans UNCoordinated family member (unc-7) (unc-7) mRNA, complete cds. 11/11 None
SNAP00000025819 ENSEMBL cdna:SNAP chromosome:CEL140:X:15121738:15123416:-1 11/11 None
GENEFINDER00000025823 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:15121738:15125103:-1 9/11 None
R07D5.1 ENSEMBL cdna:known chromosome:CEL140:X:15121738:15127490:-1 gene:R07D5.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:15121737-15127490(-) 100.0 100.0
Public Domain and Genome References
Gene Title unc-7 membrane protein
Gene Symbol unc-7
Ensembl R07D5.1
Entrez Gene 181608 Entrez gene
SwissProt Q03412 EMBL-EBI
WormBase CE06279 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5921 gap junction inferred from electronic annotation QuickGO AmiGO
5886 plasma membrane inferred from direct assay QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94607 Hypothetical protein R07D5.1 [Caenorhabditis elegans] ref|NP_510515.1| UNCoordinated family member (unc-7) [Caenorhabditis elegans] sp|Q03412|UNC7_CAEEL Innexin unc-7 (Uncoordinated protein 7) emb|CAA79529.1| hypothetical polypeptide [Caenorhabditis elegans] 0.0
blast CAE63255 Hypothetical protein CBG07625 [Caenorhabditis briggsae] 0.0
blast CAA94607 Hypothetical protein R07D5.1 [Caenorhabditis elegans] ref|NP_510515.1| UNCoordinated family member (unc-7) [Caenorhabditis elegans] sp|Q03412|UNC7_CAEEL Innexin unc-7 (Uncoordinated protein 7) emb|CAA79529.1| hypothetical polypeptide [Caenorhabditis elegans] 1.0E-148
blast CAE63255 Hypothetical protein CBG07625 [Caenorhabditis briggsae] 1.0E-147
blast AAN71842 Innexin protein 1, isoform a [Caenorhabditis elegans] ref|NP_741826.1| INneXin family member (inx-1) [Caenorhabditis elegans] gb|AAB09671.1| transmembrane protein 1.0E-129
Protein Domains
Database ID Description E-Value
Pfam IPR000990 EMBL-EBI Innexin 1.0E-126
Pfam IPR000990 EMBL-EBI Innexin 1.0E-126
Pfam IPR000990 EMBL-EBI Innexin 1.7E-98
Pfam IPR000990 EMBL-EBI Innexin 2.1E-101
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510515.1 3 222-244,318-340,408-430
R07D5.1 3 222-244,318-340,408-430
SNAP00000025819 2 60-82,150-172
GENEFINDER00000025823 4 35-52,65-87,140-162,318-340
Sequence
Target Sequence 
>C. ELEGANS:192738_AT
gaatcaaggttctctactcagcaaatgtgttgctccagtttttcttgctgaaccatcttc
ttgggtctaacgacttggcttatggattctctttgttgaaagacttgatgcacgcgattg
agtgggaacagactggaatgttccccagggtcacactttgtgattttgaggttcgagttc
tgggaaacattcatcgacataccgttcagtgcgtgttaatgatcaatatgtttaatgaga
aaattttcttattcctctggttttggttcttaacctgtggaattgttaccgtatgtaaca
ctatgtactggattctcattatgttcattccgtctcagggaatgtcatttgtccgcaaat
acctccgtgttctacctgaccaccctgcgaaaccaatagctgatgacgtcacgctgagga
agttcactaataacttcctccgcaaagatggagtcttcatgttgcgaatgatttccacac
acgccggcgaactgatgagcagtgagctcattcttgctctctggcaggatttcaacaacg
tcgaccgcagtccgacgcaattttggga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATCAAGGTTCTCTACTCAGCAAA 388 327 983 Antisense
AATGTGTTGCTCCAGTTTTTCTTGC 383 163 1006 Antisense
GCTGAACCATCTTCTTGGGTCTAAC 312 295 1029 Antisense
ATTCATCGACATACCGTTCAGTGCG 682 9 1171 Antisense
CTCATTATGTTCATTCCGTCTCAGG 613 229 1297 Antisense
ACCACCCTGCGAAACCAATAGCTGA 635 81 1361 Antisense
AGTTCACTAATAACTTCCTCCGCAA 62 65 1403 Antisense
TCCACACACGCCGGCGAACTGATGA 103 589 1456 Antisense
CAGTGAGCTCATTCTTGCTCTCTGG 464 207 1482 Antisense
GCAGGATTTCAACAACGTCGACCGC 424 311 1506 Antisense
ACCGCAGTCCGACGCAATTTTGGGA 395 89 1526 Antisense
Sequence Source Affymetrix Proprietary Database