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[192733_at] tyosine-protein kinase

Description T06C10.6 /REP_DB=WormBase Gene ID /WP=CE04904 /GEN=kin-26 /TR=Q22245 /GB=AAA82302.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=tyosine-protein kinase
Cluster 6grp_total > 85      4grp_total > 20      6grp_cgc > 68      6grp_cgc_sub > In      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 72
1 2 3 4 range
A 35.9
(-3)
A 		61
(-0.7)
A 		49
(-1.8)
A 		102
(3)
A 		66
B 57.6
(2.6)
P 		51.4
(1.1)
A 		35.2
(-3)
A 		59
(3)
A 		24
C 62.5
(3)
A 		52.6
(1.2)
A 		30
(-3)
A 		48.8
(0.5)
A 		33
avr 52
(-0.4) 		55
(0.2) 		38.1
(-3) 		69.9
(3) 		32

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 116
1 2 3 4 5 6 range
A 12.3
(-2.9)
A 		10.3
(-3)
A 		47.2
(-1.1)
P 		74.5
(0.3)
A 		71.3
(0.2)
A 		125.4
(3)
A 		115
B 28.2
(-1.6)
A 		9.8
(-3)
A 		24.5
(-1.9)
A 		67
(1.3)
A 		69.9
(1.5)
P 		89.1
(3)
P 		79
C 27.6
(-1.5)
A 		54.2
(0.9)
A 		10.7
(-3)
A 		74.4
(2.7)
A 		77.5
(3)
A 		73.3
(2.6)
P 		67
avr 22.7
(-3) 		24.8
(-2.8) 		27.5
(-2.6) 		72
(1) 		72.9
(1.1) 		95.9
(3) 		73
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 13.1
(-2.1)
A 		13.2
(-1.9)
A 		12.8
(-3)
A 		14.9
(3)
A 		2
B 18.4
(3)
P 		12.7
(-0.4)
A 		8.2
(-3)
A 		12.6
(-0.4)
A 		10
C 20.7
(3)
A 		15.1
(0.3)
A 		10.4
(-1.9)
A 		8.2
(-3)
A 		13
avr 17.4
(3) 		13.7
(-0.2) 		10.5
(-3) 		11.9
(-1.8) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 31
1 2 3 4 5 6 range
A 2.3
(-3)
A 		3.7
(-2.7)
A 		10.3
(-1.3)
P 		18.9
(0.5)
A 		21.5
(1.1)
A 		30.5
(3)
A 		28
B 9.8
(-1.7)
A 		3.3
(-3)
A 		5.9
(-2.5)
A 		17.7
(-0.1)
A 		28.4
(2)
P 		33.2
(3)
P 		30
C 10.2
(-1)
A 		16.5
(0.7)
A 		2.7
(-3)
A 		15
(0.3)
A 		25.1
(3)
A 		24.5
(2.8)
P 		22
avr 7.4
(-2.7) 		7.8
(-2.6) 		6.3
(-3) 		17.2
(-0.2) 		25
(1.9) 		29.4
(3) 		23
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192733_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10002
Sequence Type Exemplar sequence
Representative Public ID T06C10.6 NCBI
Target Description T06C10.6 /REP_DB=WormBase Gene ID /WP=CE04904 /GEN=kin-26 /TR=Q22245 /GB=AAA82302.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=tyosine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068908(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068908 NCBI Caenorhabditis elegans protein KINase family member (kin-26) (kin-26) mRNA, complete cds. 11/11 None
SNAP00000043498 ENSEMBL cdna:SNAP chromosome:CEL140:IV:7875735:7877606:-1 11/11 None
GENEFINDER00000043507 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:7875735:7877201:-1 11/11 None
T06C10.6 ENSEMBL cdna:known chromosome:CEL140:IV:7875735:7877785:-1 gene:T06C10.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:7875740-7877791(-) 100.0 100.0
Public Domain and Genome References
Gene Title tyosine-protein kinase
Gene Symbol kin-26
Ensembl T06C10.6
Entrez Gene 177575 Entrez gene
SwissProt Q22245 EMBL-EBI
WormBase CE04904 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_501309 protein KINase family member (kin-26) [Caenorhabditis elegans] gb|AAA82302.1| Protein kinase protein 26 [Caenorhabditis elegans] 0.0
blast AAB37087 Protein kinase protein 31 [Caenorhabditis elegans] ref|NP_498912.3| protein KINase family member (kin-31) [Caenorhabditis elegans] sp|P34265|KIN31_CAEEL Probable tyrosine-protein kinase kin-31 1.0E-169
blast AAB37087 Protein kinase protein 31 [Caenorhabditis elegans] ref|NP_498912.3| protein KINase family member (kin-31) [Caenorhabditis elegans] sp|P34265|KIN31_CAEEL Probable tyrosine-protein kinase kin-31 1.0E-167
blast G88535 protein B0523.1 [imported] - Caenorhabditis elegans 1.0E-151
blast G88535 protein B0523.1 [imported] - Caenorhabditis elegans 1.0E-149
Protein Families
Method ID Description E-Value
hanks 1.9.5 AGC group; AGC Other; DdK2 9.0E-65
hanks 1.9.5 AGC group; AGC Other; DdK2 8.0E-65
hanks 1.9.5 AGC group; AGC Other; DdK2 7.0E-65
Protein Domains
Database ID Description E-Value
Pfam IPR000980 EMBL-EBI SH2 motif 4.6E-18
Pfam IPR000719 EMBL-EBI Protein kinase 7.2E-56
Pfam IPR000980 EMBL-EBI SH2 motif 4.6E-18
Pfam IPR000719 EMBL-EBI Protein kinase 7.2E-56
Pfam IPR000719 EMBL-EBI Protein kinase 7.2E-56
Sequence
Target Sequence 
>C. ELEGANS:192733_AT
aaatcacctattcgttggttggctattgagacaatcaaaacaatgatttgttctgaaaag
accgatgtctgggcttacggtgttctttgctgggagatcttcaataatgcagccgaacca
tatccgggaatgaagcctgccgacgtcgctacacaagttgcaaatggataccgtatgcca
ccgtacccacatgctcaggctgagattcaaacaatgatggcgagatgcaatgctgaaaat
ccgaatgatcgtccatcaatggctgaaattgctgaaatcctacaacgtgtcactgaaact
cctcgccccaattttacagccatagcgaagaaagaggcagaggagcttctcctaatgaac
tctgtaactacgaaaacaactgctcgtcgcaagaagtcta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAATCACCTATTCGTTGGTTGGCTA 19 115 880 Antisense
CCGATGTCTGGGCTTACGGTGTTCT 248 261 941 Antisense
CGGTGTTCTTTGCTGGGAGATCTTC 289 243 957 Antisense
AATGCAGCCGAACCATATCCGGGAA 334 165 985 Antisense
ATCCGGGAATGAAGCCTGCCGACGT 450 37 1001 Antisense
TGCCGACGTCGCTACACAAGTTGCA 279 583 1017 Antisense
GTACCCACATGCTCAGGCTGAGATT 178 459 1062 Antisense
TACAACGTGTCACTGAAACTCCTCG 297 641 1160 Antisense
TCGCCCCAATTTTACAGCCATAGCG 422 599 1182 Antisense
AGGAGCTTCTCCTAATGAACTCTGT 586 55 1220 Antisense
ACAACTGCTCGTCGCAAGAAGTCTA 533 111 1255 Antisense
Sequence Source Affymetrix Proprietary Database