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[192705_s_at] aromatic-L-amino-acid decarboxylase

Description C05D2.3 /REP_DB=WormBase Gene ID /WP=CE01140 /TR=O45138 /GB=AAC02720.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=aromatic-L-amino-acid decarboxylase
Cluster 6grp_high1_10_10 > 79      4grp_high_8_8 > 22      6grp_total > 89      4grp_total > 25      6grp_high1_sub > Cu      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 91
1 2 3 4 range
A 50.2
(-3)
A 		71.4
(-1.1)
A 		91.4
(0.7)
P 		116.2
(3)
P 		66
B 57.4
(0.8)
P 		69.9
(3)
P 		58.1
(1)
A 		35.2
(-3)
P 		35
C 38.1
(-3)
A 		73.5
(-0.6)
A 		51.5
(-2.1)
P 		126.2
(3)
P 		88
avr 48.6
(-3) 		71.6
(0.1) 		67
(-0.5) 		92.5
(3) 		44

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 147
1 2 3 4 5 6 range
A 73.1
(-1.9)
A 		80.9
(-1.6)
P 		63.3
(-2.4)
P 		50.2
(-3)
P 		140.5
(1.2)
P 		180.3
(3)
P 		130
B 42.7
(-2.5)
P 		78.5
(-0.7)
P 		33.3
(-3)
P 		63.8
(-1.4)
A 		99.6
(0.4)
P 		148.8
(3)
P 		116
C 72.1
(-1.3)
P 		54.6
(-2.6)
A 		50
(-3)
A 		64.1
(-1.9)
A 		122.4
(2.5)
P 		128.4
(3)
P 		78
avr 62.6
(-2.2) 		71.3
(-1.7) 		48.9
(-3) 		59.4
(-2.4) 		120.8
(1.2) 		152.5
(3) 		104
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 16
1 2 3 4 range
A 18.3
(-1)
A 		15.5
(-3)
A 		23.9
(3)
P 		17
(-1.9)
P 		8
B 18.3
(3)
P 		17.3
(2.4)
P 		13.5
(0.3)
A 		7.5
(-3)
P 		11
C 12.6
(-3)
A 		21.1
(2.9)
A 		18
(0.7)
P 		21.3
(3)
P 		9
avr 16.4
(-0.9) 		18
(2.1) 		18.5
(3) 		15.3
(-3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 47
1 2 3 4 5 6 range
A 13.5
(-2.8)
A 		28.8
(0.1)
P 		13.8
(-2.8)
P 		12.7
(-3)
P 		42.4
(2.7)
P 		43.9
(3)
P 		31
B 14.9
(-2.1)
P 		26.1
(-0.7)
P 		8.1
(-3)
P 		16.9
(-1.9)
A 		40.5
(1.1)
P 		55.5
(3)
P 		47
C 26.7
(-0.2)
P 		16.6
(-2.2)
A 		12.7
(-3)
A 		12.9
(-3)
A 		39.6
(2.3)
P 		43
(3)
P 		30
avr 18.4
(-1.9) 		23.8
(-1) 		11.5
(-3) 		14.2
(-2.6) 		40.8
(1.9) 		47.5
(3) 		36
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192705_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6618
Sequence Type Exemplar sequence
Representative Public ID C05D2.3 NCBI
Target Description C05D2.3 /REP_DB=WormBase Gene ID /WP=CE01140 /TR=O45138 /GB=AAC02720.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=aromatic-L-amino-acid decarboxylase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065809(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065809 NCBI Caenorhabditis elegans C05D2.3 (C05D2.3) mRNA, complete cds. 11/11 A 
SNAP00000007737 ENSEMBL cdna:SNAP chromosome:CEL140:III:5614924:5617166:1 11/11 None
GENEFINDER00000007747 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:5614924:5617166:1 11/11 None
C05D2.3 ENSEMBL cdna:known chromosome:CEL140:III:5614924:5617201:1 gene:C05D2.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:5614922-5617037(+) 100.0 100.0
Public Domain and Genome References
Gene Title aromatic-L-amino-acid decarboxylase
Ensembl C05D2.3
Entrez Gene 175779 Entrez gene
SwissProt O45138 EMBL-EBI
WormBase CE29022 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6520 amino acid metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16831 carboxy-lyase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC02720 Hypothetical protein C05D2.3 [Caenorhabditis elegans] ref|NP_498210.1| C05D2.3 [Caenorhabditis elegans] 0.0
blast AAV58886 Biogenic amine synthesis related protein 1, isoform a [Caenorhabditis elegans] ref|NP_001021150.1| Biogenic Amine Synthesis related family member (bas-1) [Caenorhabditis elegans] 0.0
blast AAC02721 Biogenic amine synthesis related protein 1, isoform b [Caenorhabditis elegans] ref|NP_001021151.1| Biogenic Amine Synthesis related family member (bas-1) [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 2.9E-37
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 2.8E-50
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 8.2E-23
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 9.5E-26
Sequence
Target Sequence 
>C. ELEGANS:192705_S_AT
cctcgctttgctcttcacaaaaatcattgtggagggtgataagtttgaactctttacacc
accacaccttggaatggctaccttccgtttgaaaaatcacaccaactctgacaacgagcg
tctcttgcaagccatcaaccgtgaccgccgtatccacttgggtatctccatggt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCTCGCTTTGCTCTTCACAAAAATC 256 267 1254 Antisense
CATTGTGGAGGGTGATAAGTTTGAA 498 37 1278 Antisense
TAAGTTTGAACTCTTTACACCACCA 571 609 1293 Antisense
TACACCACCACACCTTGGAATGGCT 381 641 1308 Antisense
ACCACACCTTGGAATGGCTACCTTC 209 85 1314 Antisense
TTGGAATGGCTACCTTCCGTTTGAA 551 653 1322 Antisense
GCTACCTTCCGTTTGAAAAATCACA 458 303 1330 Antisense
GAAAAATCACACCAACTCTGACAAC 35 357 1344 Antisense
ACCAACTCTGACAACGAGCGTCTCT 455 85 1354 Antisense
TGACAACGAGCGTCTCTTGCAAGCC 623 571 1362 Antisense
GTATCCACTTGGGTATCTCCATGGT 559 455 1403 Antisense
Sequence Source Affymetrix Proprietary Database