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[192668_s_at] WD domain, G-beta repeat (2 domains)

Description F10F2.1 /REP_DB=WormBase Gene ID /WP=CE00946 /TR=Q19317 /GB=CAA86337.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=WD domain, G-beta repeat (2 domains)
Cluster 6grp_highest_10_10 > 51      6grp_high1_10_10 > 25      4grp_highest_8_8 > 43      4grp_high_8_8 > 40      6grp_highest_nonorm > 75      6grp_total > 25      4grp_total > 55      6grp_highest_sub > De      6grp_high1_sub > 01_02      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 810
1 2 3 4 range
A 1350.9
(3)
P 		541.4
(-3)
P 		727.2
(-1.6)
P 		599.1
(-2.6)
P 		810
B 1106
(3)
P 		755.9
(-2.4)
P 		717.9
(-3)
P 		744.5
(-2.6)
P 		388
C 1273.8
(3)
P 		687.6
(-2.1)
P 		826.1
(-0.9)
P 		581.4
(-3)
P 		692
avr 1243.6
(3) 		661.6
(-2.8) 		757.1
(-1.8) 		641.7
(-3) 		602

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 652
1 2 3 4 5 6 range
A 728.4
(-1.1)
P 		1069.5
(3)
P 		571
(-3)
P 		773.6
(-0.6)
P 		650.1
(-2)
P 		835.5
(0.2)
P 		499
B 1223
(3)
P 		990.1
(0.8)
P 		816.9
(-0.9)
P 		948.4
(0.4)
P 		597
(-3)
P 		736.2
(-1.7)
P 		626
C 1108.1
(3)
P 		868.5
(-0.7)
P 		967.8
(0.8)
P 		741.1
(-2.6)
P 		718
(-3)
P 		743.2
(-2.6)
P 		390
avr 1019.8
(3) 		976
(2.3) 		785.2
(-0.9) 		821
(-0.3) 		655
(-3) 		771.6
(-1.1) 		365
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 404
1 2 3 4 range
A 491.9
(3)
P 		117.5
(-2.6)
P 		190.1
(-1.5)
P 		87.7
(-3)
P 		404
B 352.7
(3)
P 		186.7
(-2.1)
P 		166.3
(-2.8)
P 		158.6
(-3)
P 		194
C 421.6
(3)
P 		197.7
(-1.2)
P 		287.9
(0.5)
P 		98
(-3)
P 		324
avr 422.1
(3) 		167.3
(-2) 		214.8
(-1) 		114.8
(-3) 		307

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 301
1 2 3 4 5 6 range
A 134.3
(-2.8)
P 		380.4
(3)
P 		124.4
(-3)
P 		196.2
(-1.3)
P 		196.2
(-1.3)
P 		203.4
(-1.1)
P 		256
B 425.6
(3)
P 		329.6
(0.5)
P 		198.4
(-3)
P 		251.2
(-1.6)
P 		242.5
(-1.8)
P 		274.5
(-1)
P 		227
C 410.7
(3)
P 		265
(-0.3)
P 		246.3
(-0.8)
P 		149
(-3)
P 		232.3
(-1.1)
P 		248.8
(-0.7)
P 		262
avr 323.5
(2.9) 		325
(3) 		189.7
(-3) 		198.8
(-2.6) 		223.7
(-1.5) 		242.2
(-0.7) 		135
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192668_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6043
Sequence Type Exemplar sequence
Representative Public ID F10F2.1 NCBI
Target Description F10F2.1 /REP_DB=WormBase Gene ID /WP=CE00946 /TR=Q19317 /GB=CAA86337.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=WD domain, G-beta repeat (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065538(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065538 NCBI Caenorhabditis elegans F10F2.1 (F10F2.1) mRNA, complete cds. 11/11 None
SNAP00000042247 ENSEMBL cdna:SNAP chromosome:CEL140:III:4596408:4598978:-1 11/11 None
GENEFINDER00000042257 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4596408:4599160:-1 11/11 None
F10F2.1 ENSEMBL cdna:known chromosome:CEL140:III:4596107:4612300:-1 gene:F10F2.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4596407-4612300(-) 100.0 100.0
Public Domain and Genome References
Gene Title WD domain, G-beta repeat (2 domains)
Ensembl F10F2.1
Entrez Gene 175606 Entrez gene
SwissProt Q19317 EMBL-EBI
WormBase CE32621 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1585956_AT similar to neurobeachin cfa
CANINE_2:CFA.15635.1.A1_S_AT similar to neurobeachin cfa
CANINE_2:CFAAFFX.10367.1.S1_AT similar to neurobeachin cfa
DROSOPHILA_2:1628143_A_AT rugose dm
DROSGENOME1:152922_AT rugose dm
CHICKEN:GGA.18.1.S1_AT similar to neurobeachin gga
CHICKEN:GGAAFFX.10928.1.S1_AT similar to neurobeachin gga
HG-U133_PLUS_2:221207_S_AT neurobeachin hs
HG-U133A:221207_S_AT neurobeachin hs
HG-FOCUS:221207_S_AT neurobeachin hs
HG-U133A_2:221207_S_AT neurobeachin hs
HU35KSUBA:RC_AA460541_AT neurobeachin hs
HU35KSUBB:RC_H15123_F_AT neurobeachin hs
HU35KSUBC:RC_AA406301_AT neurobeachin hs
HU35KSUBD:RC_AA431429_AT neurobeachin hs
HU35KSUBD:RC_C14834_F_AT neurobeachin hs
U133_X3P:G7657362_3P_A_AT neurobeachin hs
U133_X3P:HS.3821.1.S1_3P_A_AT neurobeachin hs
HG-U133_PLUS_2:226439_S_AT neurobeachin hs
HG-U133B:226439_S_AT neurobeachin hs
HG-U95B:49785_AT neurobeachin hs
HG-U95B:52828_AT neurobeachin hs
HG-U95C:56809_AT neurobeachin hs
HG-U95C:64359_R_AT Neurobeachin hs
HG-U95E:72607_AT Neurobeachin hs
Protein Similarities
Method ID Description E-Value
blast CAA86337 Hypothetical protein F10F2.1 [Caenorhabditis elegans] emb|CAA84657.2| Hypothetical protein F10F2.1 [Caenorhabditis elegans] ref|NP_497939.2| F10F2.1 [Caenorhabditis elegans] sp|Q19317|NBEA_CAEEL Putative neurobeachin homolog 0.0
blast CAE71172 Hypothetical protein CBG18029 [Caenorhabditis briggsae] 0.0
blast CAC18800 AKAP550 [Drosophila melanogaster] 0.0
blast EAL32473 GA19855-PA [Drosophila pseudoobscura] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR010508 EMBL-EBI Protein of unknown function DUF1088 1.0E-126
Pfam IPR000409 EMBL-EBI Beige/BEACH domain 1.0E-126
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.3E-7
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 5.4E-6
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.11
Pfam IPR000409 EMBL-EBI Beige/BEACH domain 1.0E-126
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.3E-7
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 5.4E-6
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.11
Pfam IPR000409 EMBL-EBI Beige/BEACH domain 1.0E-126
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.3E-7
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 5.4E-6
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.11
Sequence
Target Sequence 
>C. ELEGANS:192668_S_AT
ctccacgttctattctgactggccacgaggcttcgatttctgcgttgtgcgtgtctgctg
aacatggactagttgtcagtggttgtgaggatggtgtcattttgattcacacgacatctt
cggatcttcttcgtcgtattcgtggacatggaatcgtaactcaactatcaatgagcagag
aatgcattttgctctcattattcgattcgaaacgaatggttacttattcagcgacggcta
agaagcttgatgaagtgttggttgatgataaaatcgaatgcgtaactgtcactcgtgatg
gtgaatttgcggtaactggagcagtgaatggaagaataaatatttggagaatgttcccac
ttacaaagttatacacatatcagcccctcaatagcgccgttcggtctgtcgcagttgttg
cttcccatcgtttcattcttggtggccttgattctggagccatcgtcgttttcaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTCCACGTTCTATTCTGACTGGCCA 644 235 7031 Antisense
TGACTGGCCACGAGGCTTCGATTTC 44 571 7046 Antisense
GTTGTGCGTGTCTGCTGAACATGGA 631 435 7074 Antisense
CACACGACATCTTCGGATCTTCTTC 348 195 7138 Antisense
GCATTTTGCTCTCATTATTCGATTC 159 309 7214 Antisense
ATGGTTACTTATTCAGCGACGGCTA 400 51 7246 Antisense
GAATGCGTAACTGTCACTCGTGATG 287 331 7306 Antisense
AAAGTTATACACATATCAGCCCCTC 292 123 7395 Antisense
CTTCCCATCGTTTCATTCTTGGTGG 74 219 7451 Antisense
TTCTTGGTGGCCTTGATTCTGGAGC 581 689 7466 Antisense
TTCTGGAGCCATCGTCGTTTTCAAT 173 693 7482 Antisense
Sequence Source Affymetrix Proprietary Database