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[192644_at] heat shock 70 protein

Description C37H5.8 /REP_DB=WormBase Gene ID /WP=CE08631 /GEN=hsp-6 /TR=SW:P11141 /GB=AAB42371.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=heat shock 70 protein
Cluster 6grp_highest_10_10 > 62      6grp_high1_10_10 > 26      4grp_highest_8_8 > 55      4grp_high_8_8 > 19      6grp_highest_nonorm > 40      6grp_total > 25      4grp_total > 28      6grp_highest_sub > Cu      6grp_cgc > 24      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 600
1 2 3 4 range
A 1411.5
(1.7)
P 		1494.7
(3)
P 		1116.5
(-3)
P 		1415
(1.7)
P 		378
B 1367.9
(-2.7)
P 		1349.9
(-3)
P 		1514.2
(-0.3)
P 		1716.3
(3)
P 		366
C 1461.3
(3)
P 		1373.6
(0.3)
P 		1374
(0.3)
P 		1267.6
(-3)
P 		194
avr 1413.6
(0.6) 		1406.1
(0.3) 		1334.9
(-3) 		1466.3
(3) 		131

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1068
1 2 3 4 5 6 range
A 898.4
(1.1)
P 		1163.1
(3)
P 		558.6
(-1.4)
P 		343.1
(-3)
P 		347.6
(-3)
P 		498.1
(-1.9)
P 		820
B 847.4
(3)
P 		783.4
(2.4)
P 		520.3
(-0.2)
P 		531.5
(-0.1)
P 		236
(-3)
P 		467.9
(-0.7)
P 		611
C 1304.2
(3)
P 		683.2
(-0.8)
P 		739
(-0.5)
P 		330
(-3)
P 		371.3
(-2.7)
P 		484.9
(-2)
P 		974
avr 1016.7
(3) 		876.6
(1.8) 		606
(-0.5) 		401.5
(-2.3) 		318.3
(-3) 		483.6
(-1.6) 		698
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 307
1 2 3 4 range
A 513.9
(3)
P 		324.5
(-0.7)
P 		291.9
(-1.3)
P 		207.1
(-3)
P 		307
B 436.2
(3)
P 		333.4
(-3)
P 		350.9
(-2)
P 		365.7
(-1.1)
P 		103
C 483.7
(3)
P 		394.9
(1)
P 		478.9
(2.9)
P 		213.7
(-3)
P 		270
avr 477.9
(3) 		350.9
(-0.5) 		373.9
(0.1) 		262.2
(-3) 		216

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 417
1 2 3 4 5 6 range
A 165.6
(-1.6)
P 		413.6
(3)
P 		121.6
(-2.4)
P 		87
(-3)
P 		104.9
(-2.7)
P 		121.3
(-2.4)
P 		327
B 294.9
(3)
P 		260.8
(2)
P 		126.3
(-2.1)
P 		140.8
(-1.6)
P 		95.9
(-3)
P 		174.5
(-0.6)
P 		199
C 483.4
(3)
P 		208.5
(-1)
P 		188.1
(-1.2)
P 		66.4
(-3)
P 		120.1
(-2.2)
P 		162.3
(-1.6)
P 		417
avr 314.6
(3) 		294.3
(2.4) 		145.3
(-1.7) 		98.1
(-3) 		107
(-2.8) 		152.7
(-1.5) 		217
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192644_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14791
Sequence Type Exemplar sequence
Representative Public ID C37H5.8 NCBI
Target Description C37H5.8 /REP_DB=WormBase Gene ID /WP=CE08631 /GEN=hsp-6 /TR=SW:P11141 /GB=AAB42371.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=heat shock 70 protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071890(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071890 NCBI Caenorhabditis elegans Heat Shock Protein family member (hsp-6) (hsp-6) mRNA, complete cds. 11/11 None
SNAP00000016581 ENSEMBL cdna:SNAP chromosome:CEL140:V:4824419:4826569:-1 11/11 None
GENEFINDER00000016594 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:4824419:4826569:-1 11/11 None
C37H5.8 ENSEMBL cdna:known chromosome:CEL140:V:4823911:4826917:-1 gene:C37H5.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:4824418-4826569(-) 100.0 100.0
Public Domain and Genome References
Gene Title heat shock 70 protein
Gene Symbol hsp-6
Ensembl C37H5.8
Entrez Gene 178873 Entrez gene
SwissProt P11141 EMBL-EBI
WormBase CE08631 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:250502_AT heat shock protein 70 / HSP70 (HSC70-5) at
CANINE:1598204_S_AT similar to Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT) cfa
CANINE_2:CFA.13016.1.S1_AT similar to Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT) cfa
CANINE_2:CFA.21133.1.S1_S_AT similar to Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT) cfa
CANINE_2:CFAAFFX.2828.1.S1_S_AT similar to Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT) cfa
DROSOPHILA_2:1627109_AT Heat shock protein cognate 5 dm
DROSGENOME1:153311_AT Heat shock protein cognate 5 dm
CHICKEN:GGA.8183.1.S1_S_AT heat shock 70kDa protein 9B (mortalin-2) gga
CHICKEN:GGAAFFX.11589.1.S1_AT heat shock 70kDa protein 9B (mortalin-2) gga
HG-U95AV2:41510_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133_PLUS_2:200690_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133A_2:200690_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133A:200690_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133_PLUS_2:200692_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133A:200692_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133A_2:200692_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133_PLUS_2:232200_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133B:232200_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133_PLUS_2:200691_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133A:200691_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-FOCUS:200691_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133A_2:200691_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HU35KSUBA:HUM_ALU_AT heat shock 70kDa protein 9B (mortalin-2) hs
HU35KSUBB:HUM_ALU_AT heat shock 70kDa protein 9B (mortalin-2) hs
HU35KSUBC:HUM_ALU_AT heat shock 70kDa protein 9B (mortalin-2) hs
HU35KSUBD:HUM_ALU_AT heat shock 70kDa protein 9B (mortalin-2) hs
HUGENEFL:HUM_ALU_AT heat shock 70kDa protein 9B (mortalin-2) hs
HC-G110:HUM_ALU_AT heat shock 70kDa protein 9B (mortalin-2) hs
HUGENEFL:L15189_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HUGENEFL:L11066_AT heat shock 70kDa protein 9B (mortalin-2) hs
U133_X3P:G4758569_3P_A_AT heat shock 70kDa protein 9B (mortalin-2) hs
U133_X3P:G12653414_3P_A_AT heat shock 70kDa protein 9B (mortalin-2) hs
U133_X3P:HS.254467.0.S1_3P_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U95D:75250_S_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U95AV2:41509_AT heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133_PLUS_2:241840_AT Heat shock 70kDa protein 9B (mortalin-2) hs
HG-U133B:241840_AT Heat shock 70kDa protein 9B (mortalin-2) hs
HG-U95D:86392_AT Heat shock 70kDa protein 9B (mortalin-2) hs
U133_X3P:HS.184233.0.A1_3P_AT Heat shock 70kDa protein 9B (mortalin-2) hs
MOE430A:1418503_AT heat shock protein 9A mm
MOUSE430_2:1418503_AT heat shock protein 9A mm
MOUSE430A_2:1418503_AT heat shock protein 9A mm
MOUSE430_2:1418504_AT heat shock protein 9A mm
MOE430A:1418504_AT heat shock protein 9A mm
MOUSE430A_2:1418504_AT heat shock protein 9A mm
MU11KSUBA:D17666_S_AT heat shock protein 9A mm
MU11KSUBB:MSA.6667.0_F_AT heat shock protein 9A mm
MU11KSUBB:MSA.37326.0_S_AT heat shock protein 9A mm
MG-U74AV2:97914_AT heat shock protein 9A mm
MOE430A:1453811_AT heat shock protein 9A mm
MOUSE430A_2:1453811_AT heat shock protein 9A mm
MOUSE430_2:1453811_AT heat shock protein 9A mm
MOE430A:1431274_A_AT heat shock protein 9A mm
MOUSE430A_2:1431274_A_AT heat shock protein 9A mm
MOUSE430_2:1431274_A_AT heat shock protein 9A mm
MOE430B:1447728_X_AT heat shock protein 9A mm
MOUSE430_2:1447728_X_AT heat shock protein 9A mm
MU11KSUBB:MSA.24278.0_S_AT Heat shock protein 9A (Hspa9a), mRNA mm
MU19KSUBA:TC23450_S_AT Heat shock protein 9A (Hspa9a), mRNA mm
MU19KSUBB:TC32883_AT Heat shock protein 9A (Hspa9a), mRNA mm
RT-U34:S75280_S_AT heat shock protein, A (predicted) rn
RG-U34A:S75280_S_AT heat shock protein, A (predicted) rn
RG-U34A:S78556_AT heat shock protein, A (predicted) rn
RG-U34A:S78556_G_AT heat shock protein, A (predicted) rn
RAE230A:1388851_AT heat shock protein, A (predicted) rn
RAT230_2:1388851_AT heat shock protein, A (predicted) rn
RAE230A:1370690_AT heat shock protein, A (predicted) rn
RAT230_2:1370690_AT heat shock protein, A (predicted) rn
RAE230B:1391915_AT heat shock protein, A (predicted) rn
RAT230_2:1391915_AT heat shock protein, A (predicted) rn
RAE230A:1389930_AT Heat shock protein, A (predicted) rn
RAT230_2:1389930_AT Heat shock protein, A (predicted) rn
RT-U34:RC_AA944973_AT Heat shock protein, A (predicted) rn
RG-U34A:RC_AA944973_AT Heat shock protein, A (predicted) rn
YEAST_2:1772031_AT Mitochondrial matrix ATPase that is a subunit of the presequence translocase-associated protein import motor (PAM); involved in protein translocation into the matrix and protein folding; member of the heat shock protein 70 (HSP70) family Sc
Protein Similarities
Method ID Description E-Value
blast AAB42371 Heat shock protein protein 6 [Caenorhabditis elegans] ref|NP_504291.1| Heat Shock Protein family member (hsp-6) [Caenorhabditis elegans] sp|P11141|HSP7F_CAEEL Heat shock 70 kDa protein F, mitochondrial precursor 0.0
blast CAE64198 Hypothetical protein CBG08827 [Caenorhabditis briggsae] 0.0
blast AAH30634 heat shock 70kD protein 9B (mortalin-2) [Homo sapiens] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001023 EMBL-EBI Heat shock protein Hsp70 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192644_AT
ccgccgatggacagactcaagtgcagatcaaggtgttccaaggagaacgtgaaatggcca
ccagcaacaaacttctcggtcaattctcgcttgtcggaattccaccagcaccacgtggtg
ttccacaagtcgaggtcacctttgacattgacgctaatggtatcgtgaacgtttcagcca
gagatcgtggaaccggaaaggaacaacagatcgttatccaatcttctggaggactttcca
aggaccaaatcgagaatatgatcaaggaagccgaaaagaatgccgctgaggacgcaaaga
gaaaggagctcgtcgaggttatcaatcaagctgaaggaatcatccacgacaccgaagcca
agatgaccgagtttgccgatcaattgccaaaggacgaatgtgaggctctccgaaccaaga
ttgctgatactaagaagattctcgacaacaaggacaatgagactccagaagctatcaagg
aggcttgcaacactcttcaacaacaatcgctcaagcttttcgaggctgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCGCCGATGGACAGACTCAAGTGCA 678 261 1373 Antisense
AATGGCCACCAGCAACAAACTTCTC 101 161 1425 Antisense
ACAAACTTCTCGGTCAATTCTCGCT 42 113 1439 Antisense
AATTCTCGCTTGTCGGAATTCCACC 123 177 1454 Antisense
AATTCCACCAGCACCACGTGGTGTT 453 177 1470 Antisense
GTGTTCCACAAGTCGAGGTCACCTT 528 485 1490 Antisense
TCCACGACACCGAAGCCAAGATGAC 275 589 1715 Antisense
TGACCGAGTTTGCCGATCAATTGCC 144 571 1736 Antisense
AATGTGAGGCTCTCCGAACCAAGAT 370 163 1769 Antisense
AAGGAGGCTTGCAACACTCTTCAAC 343 161 1849 Antisense
ATCGCTCAAGCTTTTCGAGGCTGCT 106 35 1878 Antisense
Sequence Source Affymetrix Proprietary Database