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[192642_at] potassium channel protein

Description F19D8.1 /REP_DB=WormBase Gene ID /WP=CE19800 /GEN=twk-6 /TR=Q93531 /GB=CAB01740.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster 6grp_total > 14      4grp_total > 14      6grp_cgc > 41      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 78
1 2 3 4 range
A 122.9
(1.7)
A 		71.8
(-3)
A 		105.2
(0.1)
A 		136.7
(3)
A 		65
B 143.8
(3)
A 		126.7
(1.7)
A 		65.8
(-3)
A 		132.2
(2.1)
A 		78
C 97
(-0.3)
A 		73.1
(-3)
A 		89.7
(-1.2)
M 		127.1
(3)
A 		54
avr 121.2
(1.6) 		90.5
(-2.5) 		86.9
(-3) 		132
(3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 116
1 2 3 4 5 6 range
A 129.8
(3)
A 		94.4
(0.6)
P 		98.4
(0.9)
A 		65.4
(-1.3)
A 		66.4
(-1.3)
A 		40.3
(-3)
A 		90
B 148.5
(3)
A 		119.1
(0.9)
A 		100.1
(-0.5)
A 		111.4
(0.3)
A 		66.1
(-3)
A 		75.2
(-2.3)
A 		82
C 114.3
(0.1)
P 		156.4
(3)
A 		69.3
(-3)
A 		109.9
(-0.2)
A 		95
(-1.2)
M 		86.4
(-1.8)
A 		87
avr 130.9
(3) 		123.3
(2.3) 		89.3
(-0.9) 		95.6
(-0.3) 		75.8
(-2.2) 		67.3
(-3) 		64
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 31
1 2 3 4 range
A 44.8
(3)
A 		15.6
(-3)
A 		27.5
(-0.6)
A 		20
(-2.1)
A 		29
B 45.9
(3)
A 		31.3
(0.1)
A 		15.3
(-3)
A 		28.2
(-0.5)
A 		31
C 32.1
(3)
A 		21
(-3)
A 		31.3
(2.6)
M 		21.4
(-2.8)
A 		11
avr 40.9
(3) 		22.6
(-3) 		24.7
(-2.3) 		23.2
(-2.8) 		18

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 42
1 2 3 4 5 6 range
A 23.9
(0.6)
A 		33.6
(3)
P 		21.4
(-0.1)
A 		16.6
(-1.3)
A 		20
(-0.4)
A 		9.8
(-3)
A 		24
B 51.7
(3)
A 		39.6
(0.4)
A 		24.3
(-3)
A 		29.5
(-1.9)
A 		26.9
(-2.4)
A 		28.1
(-2.2)
A 		27
C 42.3
(1.9)
P 		47.7
(3)
A 		17.6
(-3)
A 		22.1
(-2.1)
A 		30.7
(-0.4)
M 		28.9
(-0.7)
A 		30
avr 39.3
(2.7) 		40.3
(3) 		21.1
(-3) 		22.7
(-2.5) 		25.9
(-1.5) 		22.3
(-2.6) 		19
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192642_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17466
Sequence Type Exemplar sequence
Representative Public ID F19D8.1 NCBI
Target Description F19D8.1 /REP_DB=WormBase Gene ID /WP=CE19800 /GEN=twk-6 /TR=Q93531 /GB=CAB01740.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077904(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077904 NCBI Caenorhabditis elegans TWiK family of potassium channels family member (twk-23) (twk-23) mRNA, complete cds. 11/11 None
GENEFINDER00000029198 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:13817920:13821163:-1 11/11 None
F19D8.1 ENSEMBL cdna:known chromosome:CEL140:X:13817920:13821163:-1 gene:F19D8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:13817919-13821163(-) 100.0 100.0
Public Domain and Genome References
Gene Title potassium channel protein
Gene Symbol twk-23
Ensembl F19D8.1
Entrez Gene 192071 Entrez gene
SwissProt Q93531 EMBL-EBI
WormBase CE19800 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5267 potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01740 Hypothetical protein F19D8.1 [Caenorhabditis elegans] ref|NP_510305.1| TWiK family of potassium channels family member (twk-23) [Caenorhabditis elegans] 0.0
blast CAE63080 Hypothetical protein CBG07369 [Caenorhabditis briggsae] 0.0
blast CAA19494 Hypothetical protein Y37A1B.11 [Caenorhabditis elegans] ref|NP_502685.2| EGg Laying defective family member (egl-23) [Caenorhabditis elegans] 5.0E-39
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510305.1 5 44-66,140-162,169-191,231-253,284-303
F19D8.1 5 44-66,140-162,169-191,231-253,284-303
GENEFINDER00000029198 5 44-66,140-162,169-191,231-253,284-303
Sequence
Target Sequence 
>C. ELEGANS:192642_AT
gagtcttacaactatcgggcttggagatattgtgcctcggcggatggattttttacttcc
aacattaatttatatcactattggtctatggctgacgactgctttggttgaacaattggc
ggatgtttttcgattagtgcactatgctggtagacaagtgacaaatgtaaaaggaatcac
tgtttggcttggtggtcgacgactgtcaatgggtggccttatcagtacagtttgcagaag
agtgggaatgtctgataatctgataaatcaaatcaactgggaccgcaccgttatcgatgc
attggatggaaagatgccaccgacgttgccaatcttcccgtggcatttcaccgatttttt
ggaacatgatcccccattgatcgatctaagtattgacttggatcagatggatggctcatt
ttattgctccaaaccattatctgcgaagaaacaaagaagagcaagtcaaatgagtgctcc
agcaatctcatggatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGTCTTACAACTATCGGGCTTGGA 662 395 813 Antisense
GGCTTGGAGATATTGTGCCTCGGCG 700 513 830 Antisense
TATGGCTGACGACTGCTTTGGTTGA 691 651 899 Antisense
GGTCGACGACTGTCAATGGGTGGCC 468 499 1006 Antisense
GGGTGGCCTTATCAGTACAGTTTGC 199 497 1023 Antisense
GACCGCACCGTTATCGATGCATTGG 83 383 1093 Antisense
TGGAAAGATGCCACCGACGTTGCCA 621 547 1119 Antisense
TCCCGTGGCATTTCACCGATTTTTT 631 597 1148 Antisense
GAACATGATCCCCCATTGATCGATC 407 351 1174 Antisense
ATTGCTCCAAACCATTATCTGCGAA 324 7 1235 Antisense
GAGTGCTCCAGCAATCTCATGGATG 118 401 1284 Antisense
Sequence Source Affymetrix Proprietary Database