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[192640_at] nuclear hormone receptor /// ---

Description C27C7.3 /REP_DB=WormBase Gene ID /WP=CE18534 /GEN=nhr-74 /TR=Q9XVC7 /GB=CAB03929.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=nuclear hormone receptor
Cluster 6grp_total > 01      4grp_total > 49      6grp_cgc > 43      6grp_cgc_sub > 02      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 196
1 2 3 4 range
A 11.5
(-2.7)
A 		31.9
(-1.6)
A 		112.9
(3)
A 		6.9
(-3)
A 		106
B 33.4
(-2)
A 		128.4
(3)
A 		92.6
(1.1)
A 		14.6
(-3)
A 		114
C 12.2
(-3)
A 		202.9
(3)
A 		115.1
(0.2)
A 		55.2
(-1.6)
A 		191
avr 19
(-3) 		121.1
(3) 		106.9
(2.2) 		25.6
(-2.6) 		102

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 65
1 2 3 4 5 6 range
A 6.6
(-3)
A 		70.1
(3)
A 		10.7
(-2.6)
A 		11.5
(-2.5)
A 		37.1
(-0.1)
A 		13
(-2.4)
A 		64
B 13.1
(-0.8)
A 		26.5
(3)
A 		7.1
(-2.5)
A 		6.8
(-2.6)
A 		5.3
(-3)
A 		11.6
(-1.2)
A 		21
C 53.4
(3)
A 		27.8
(-0.3)
A 		13.8
(-2.1)
A 		7.1
(-3)
A 		7.2
(-3)
A 		6.9
(-3)
A 		47
avr 24.4
(-0.1) 		41.5
(3) 		10.5
(-2.6) 		8.5
(-3) 		16.5
(-1.5) 		10.5
(-2.6) 		33
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 57
1 2 3 4 range
A 4.2
(-2.3)
A 		6.9
(-1.8)
A 		29.5
(3)
A 		1
(-3)
A 		29
B 10.7
(-1.4)
A 		31.7
(3)
A 		21.5
(0.9)
A 		3.1
(-3)
A 		29
C 4
(-3)
A 		58.3
(3)
A 		40.1
(1)
A 		9.3
(-2.4)
A 		54
avr 6.3
(-2.6) 		32.3
(3) 		30.4
(2.6) 		4.5
(-3) 		28

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 24
1 2 3 4 5 6 range
A 1.2
(-3)
A 		24.9
(3)
A 		2.3
(-2.7)
A 		2.9
(-2.6)
A 		11.2
(-0.5)
A 		3.2
(-2.5)
A 		24
B 4.6
(-0.5)
A 		8.8
(3)
A 		1.7
(-3)
A 		1.8
(-2.9)
A 		2.2
(-2.6)
A 		4.3
(-0.8)
A 		7
C 19.8
(3)
A 		8.5
(-0.7)
A 		3.5
(-2.3)
A 		1.4
(-3)
A 		2.3
(-2.7)
A 		2.3
(-2.7)
A 		18
avr 8.5
(0.2) 		14.1
(3) 		2.5
(-2.8) 		2
(-3) 		5.2
(-1.4) 		3.3
(-2.4) 		12
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192640_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2421
Sequence Type Exemplar sequence
Representative Public ID C27C7.3 NCBI
Target Description C27C7.3 /REP_DB=WormBase Gene ID /WP=CE18534 /GEN=nhr-74 /TR=Q9XVC7 /GB=CAB03929.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=nuclear hormone receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060525, NM_060518
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060525 NCBI Caenorhabditis elegans ZK1025.6 (ZK1025.6) mRNA, complete cds. None
SNAP00000038818 ENSEMBL cdna:SNAP chromosome:CEL140:I:11462685:11463572:1 None
NM_060518 NCBI Caenorhabditis elegans Nuclear Hormone Receptor family member (nhr-74) (nhr-74) mRNA, complete cds. A 
C27C7.3 ENSEMBL cdna:known chromosome:CEL140:I:11437194:11440186:1 gene:C27C7.3 A 
ZK1025.6 ENSEMBL cdna:known chromosome:CEL140:I:11462902:11463572:1 gene:ZK1025.6 None
GENEFINDER00000038831 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:11462902:11463572:1 None
GENEFINDER00000039066 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:11437872:11440186:1 None
SNAP00000039061 ENSEMBL cdna:SNAP chromosome:CEL140:I:11439894:11440186:1 None
ZK1025.6 ENSEMBL cdna:known chromosome:CEL140:I:11462902:11463572:1 gene:ZK1025.6 None
SNAP00000038818 ENSEMBL cdna:SNAP chromosome:CEL140:I:11462685:11463572:1 None
GENEFINDER00000038831 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:11462902:11463572:1 None
NM_060525 NCBI Caenorhabditis elegans ZK1025.6 (ZK1025.6) mRNA, complete cds. None
SNAP00000039061 ENSEMBL cdna:SNAP chromosome:CEL140:I:11439894:11440186:1 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:11437800-11440117(+) 94.44 97.83
chrI:11462806-11463503(+) 56.31 56.31
Public Domain and Genome References
Gene Title nuclear hormone receptor

Gene Symbol nhr-74
nhr-244
Ensembl C27C7.3
ZK1025.6
Entrez Gene 191495 Entrez gene
191723 Entrez gene
SwissProt Q9XVC7 EMBL-EBI
WormBase CE34263 Wormbase
CE19333 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
3707 steroid hormone receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03929 Hypothetical protein C27C7.3 [Caenorhabditis elegans] ref|NP_492919.2| Nuclear Hormone Receptor family member (nhr-74) [Caenorhabditis elegans] 1.0E-169
blast CAB03929 Hypothetical protein C27C7.3 [Caenorhabditis elegans] ref|NP_492919.2| Nuclear Hormone Receptor family member (nhr-74) [Caenorhabditis elegans] 1.0E-164
blast CAA18369 Hypothetical protein ZK1025.10 [Caenorhabditis elegans] ref|NP_492932.1| ZK1025.10 [Caenorhabditis elegans] 2.0E-98
blast CAB03929 Hypothetical protein C27C7.3 [Caenorhabditis elegans] ref|NP_492919.2| Nuclear Hormone Receptor family member (nhr-74) [Caenorhabditis elegans] 3.0E-98
blast CAA18369 Hypothetical protein ZK1025.10 [Caenorhabditis elegans] ref|NP_492932.1| ZK1025.10 [Caenorhabditis elegans] 1.0E-97
blast CAA18364 Hypothetical protein ZK1025.6 [Caenorhabditis elegans] ref|NP_492926.1| ZK1025.6 [Caenorhabditis elegans] 8.0E-96
Protein Domains
Database ID Description E-Value
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 1.7E-12
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 1.7E-12
Sequence
Target Sequence 
>C. ELEGANS:192640_AT
gaggagttcagtgatattctggataacaccctccacgtgagttctatcaccgacctaatg
attgtctccgctcatcacgagggatcttccacagaatcctgccttaactgccctggagtt
gatatgctagacaaggaagatgtggaggttctgctgaagtacttcaagttctccaatacc
tggattgattcgatatttgctagcttgatatctcccaatcaagtggagcttatccagtgc
gatcatgaggacattgccaaattcatcaatcattccaaatcaaccttaggattcagccta
agccatcttaatctgaacatcatcgagtactcagtcttcaagtccttctgtatctggaag
cttgtgtatcatgagacaagcatcgcaatgaagattatggctcaagagcattttgagggt
gttaccagtgctctccggaagtattacagggtaaggggaacctattattttctgctgaag
tcctgttgtgcctgttttcagaaggaatccaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGGAGTTCAGTGATATTCTGGATA 26 405 445 Antisense
ATATTCTGGATAACACCCTCCACGT 322 19 458 Antisense
ATAACACCCTCCACGTGAGTTCTAT 312 25 467 Antisense
CCTCCACGTGAGTTCTATCACCGAC 50 267 474 Antisense
ACGTGAGTTCTATCACCGACCTAAT 336 93 479 Antisense
CACCGACCTAATGATTGTCTCCGCT 183 201 492 Antisense
AAGGGGAACCTATTATTTTCTGCTG 607 159 897 Antisense
GAACCTATTATTTTCTGCTGAAGTC 16 347 902 Antisense
ATTTTCTGCTGAAGTCCTGTTGTGC 197 15 911 Antisense
GTCCTGTTGTGCCTGTTTTCAGAAG 169 477 924 Antisense
GTGCCTGTTTTCAGAAGGAATCCAA 653 477 932 Antisense
Sequence Source Affymetrix Proprietary Database