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[192633_at] formyltetrahydrofolate dehydrogenase

Description F36H1.6 /REP_DB=WormBase Gene ID /WP=CE05817 /TR=Q19428 /GB=CAA92998.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=formyltetrahydrofolate dehydrogenase
Cluster 6grp_highest_10_10 > 17      6grp_high1_10_10 > 52      4grp_highest_8_8 > 26      4grp_high_8_8 > 59      6grp_highest_nonorm > 35      6grp_total > 62      4grp_total > 60      6grp_highest_sub > 04      6grp_cgc > 84      6grp_high1_sub > 03      6grp_cgc_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1078
1 2 3 4 range
A 1734.1
(0.8)
P 		1625.7
(0.1)
P 		2048.4
(3)
P 		1175.2
(-3)
P 		873
B 1693.1
(0.8)
P 		1418.3
(-1.3)
P 		1973.3
(3)
P 		1204.2
(-3)
P 		769
C 1728.2
(-0)
P 		1520.6
(-1.2)
P 		2253
(3)
P 		1212.1
(-3)
P 		1041
avr 1718.5
(0.5) 		1521.5
(-0.8) 		2091.6
(3) 		1197.2
(-3) 		894

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3930
1 2 3 4 5 6 range
A 1926.8
(-2.1)
P 		3082.1
(-0.2)
P 		4989.9
(3)
P 		4521.1
(2.2)
P 		3334.3
(0.3)
P 		1363.9
(-3)
P 		3626
B 2031
(-3)
P 		4133.3
(1.8)
P 		4523.7
(2.7)
P 		4674.1
(3)
P 		3351.3
(-0)
P 		2059.7
(-2.9)
P 		2643
C 1657.3
(-2.4)
P 		3707.1
(0.7)
P 		5213.3
(3)
P 		4909.2
(2.5)
P 		2782.2
(-0.7)
P 		1283.1
(-3)
P 		3930
avr 1871.7
(-2.5) 		3640.8
(0.7) 		4909
(3) 		4701.5
(2.6) 		3155.9
(-0.1) 		1568.9
(-3) 		3340
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 613
1 2 3 4 range
A 631.4
(3)
P 		352.9
(-0.6)
P 		535.5
(1.7)
P 		172
(-3)
P 		459
B 539.9
(3)
P 		350.3
(-1)
P 		457.3
(1.3)
P 		256.6
(-3)
P 		283
C 572.1
(0.8)
P 		437.2
(-0.6)
P 		785.3
(3)
P 		204.4
(-3)
P 		581
avr 581.1
(2.8) 		380.1
(-0.3) 		592.7
(3) 		211
(-3) 		382

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1044
1 2 3 4 5 6 range
A 355.2
(-2.8)
P 		1096.1
(2.6)
P 		1086.7
(2.6)
P 		1146.7
(3)
P 		1006.1
(2)
P 		332.1
(-3)
P 		815
B 706.7
(-3)
P 		1375.8
(3)
P 		1098.5
(0.5)
P 		1238
(1.8)
P 		1361.6
(2.9)
P 		768
(-2.5)
P 		669
C 614.3
(-1.8)
P 		1131.1
(1.7)
P 		1326.9
(3)
P 		987.2
(0.7)
P 		900.3
(0.1)
P 		429.5
(-3)
P 		897
avr 558.7
(-2.6) 		1201
(3) 		1170.7
(2.7) 		1124
(2.3) 		1089.3
(2) 		509.9
(-3) 		691
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192633_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8620
Sequence Type Exemplar sequence
Representative Public ID F36H1.6 NCBI
Target Description F36H1.6 /REP_DB=WormBase Gene ID /WP=CE05817 /TR=Q19428 /GB=CAA92998.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=formyltetrahydrofolate dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069653(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069653 NCBI Caenorhabditis elegans ALdehyde deHydrogenase family member (alh-3) (alh-3) mRNA, complete cds. 11/11 None
SNAP00000039954 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11023220:11025705:1 11/11 None
GENEFINDER00000039971 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11024110:11025705:1 11/11 None
F36H1.6.2 ENSEMBL cdna:known chromosome:CEL140:IV:11022571:11025824:1 gene:F36H1.6 11/11 None
F36H1.6.1 ENSEMBL cdna:known chromosome:CEL140:IV:11022573:11025830:1 gene:F36H1.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11022580-11025711(+) 100.0 100.0
Public Domain and Genome References
Gene Title formyltetrahydrofolate dehydrogenase
Gene Symbol alh-3
Ensembl F36H1.6
Entrez Gene 177999 Entrez gene
SwissProt Q19428 EMBL-EBI
WormBase CE05817 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1585525_AT similar to aldehyde dehydrogenase 1 family, member L2 cfa
CANINE_2:CFA.11405.1.A1_AT similar to aldehyde dehydrogenase 1 family, member L2 cfa
CANINE_2:CFAAFFX.3800.1.S1_S_AT similar to aldehyde dehydrogenase 1 family, member L2 cfa
DROSOPHILA_2:1631452_AT dm
DROSGENOME1:146585_AT dm
CHICKEN:GGA.11316.1.S1_AT aldehyde dehydrogenase 1 family, member L2 gga
CHICKEN:GGA.11316.1.S1_S_AT aldehyde dehydrogenase 1 family, member L2 gga
CHICKEN:GGAAFFX.8040.1.S1_S_AT aldehyde dehydrogenase 1 family, member L2 gga
HG-U95B:41933_AT aldehyde dehydrogenase 1 family, member L2 hs
HU35KSUBB:RC_AA040107_AT aldehyde dehydrogenase 1 family, member L2 hs
HU35KSUBC:RC_N21152_AT aldehyde dehydrogenase 1 family, member L2 hs
HU35KSUBD:RC_AA424511_AT aldehyde dehydrogenase 1 family, member L2 hs
U133_X3P:HS2.191600.1.S1_3P_AT aldehyde dehydrogenase 1 family, member L2 hs
U133_X3P:HS.42572.0.A1_3P_AT aldehyde dehydrogenase 1 family, member L2 hs
HG-U133_PLUS_2:1559393_AT aldehyde dehydrogenase 1 family, member L2 hs
HG-U133_PLUS_2:231202_AT aldehyde dehydrogenase 1 family, member L2 hs
HG-U133B:231202_AT aldehyde dehydrogenase 1 family, member L2 hs
HG-U95C:61416_AT aldehyde dehydrogenase 1 family, member L2 hs
HG-U95C:64663_AT aldehyde dehydrogenase 1 family, member L2 hs
U133_X3P:HS2.98407.1.S1_3P_S_AT Aldehyde dehydrogenase 1 family, member L2 hs
HG-U133_PLUS_2:1556841_A_AT Aldehyde dehydrogenase 1 family, member L2 hs
HG-U95E:79241_AT Aldehyde dehydrogenase 1 family, member L2 hs
MG-U74CV2:134438_AT aldehyde dehydrogenase 1 family, member L2 mm
MOE430B:1436119_AT aldehyde dehydrogenase 1 family, member L2 mm
MOUSE430_2:1436119_AT aldehyde dehydrogenase 1 family, member L2 mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
9058 biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
16742 hydroxymethyl-, formyl- and related transferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92998 Hypothetical protein F36H1.6 [Caenorhabditis elegans] emb|CAA92957.1| Hypothetical protein F36H1.6 [Caenorhabditis elegans] ref|NP_502054.1| ALdehyde deHydrogenase family member (alh-3) [Caenorhabditis elegans] 0.0
blast CAE61979 Hypothetical protein CBG05984 [Caenorhabditis briggsae] 0.0
blast AAH73490 MGC81015 protein [Xenopus laevis] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005793 EMBL-EBI Formyl transferase, C-terminal 4.9E-22
Pfam IPR002376 EMBL-EBI Formyl transferase, N-terminal 8.0E-54
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 1.8E-75
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 1.0E-126
Pfam IPR005793 EMBL-EBI Formyl transferase, C-terminal 4.9E-22
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 1.3E-76
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 1.0E-126
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192633_AT
agcgtgtggagcagttttcttcaataaaggagagaactgtattgctgctgggcgtgtttt
tattgcaaaatcgattcatgatgatttcgtgaagaagcttgtcgaggaagctaaacaata
tcaaattggagatcctctcgatagatcaactgctcacggtccacagaatcatttagcaca
tcttaataagctagtcgagtatgtggagaaggctgtagctggcggagctaaagttgaagt
cggtggaaaacgtttagaaagagaaggactctatttcccaccaacgattctgtcgaatat
tgacgatgaaaactttgctgcaagtgaagaatcattcggaccaatcatgtgtgtatccag
ttttgatgacgatgacatcgaagatgtactccgtagagccaatgacacagaattcggact
tgctgctggagtttttacccgtgactcgtcgaaatcacttcgtgttgctgaagctcttca
cgctggaacagtcttcgttaatacttatcagaaaactgatgtggcagctccattcggt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGCGTGTGGAGCAGTTTTCTTCAAT 616 81 2049 Antisense
AGAACTGTATTGCTGCTGGGCGTGT 386 73 2081 Antisense
TCCTCTCGATAGATCAACTGCTCAC 449 593 2181 Antisense
AACTGCTCACGGTCCACAGAATCAT 199 143 2196 Antisense
ATTTCCCACCAACGATTCTGTCGAA 261 17 2321 Antisense
TACTCCGTAGAGCCAATGACACAGA 149 627 2435 Antisense
GACACAGAATTCGGACTTGCTGCTG 162 367 2452 Antisense
TGCTGCTGGAGTTTTTACCCGTGAC 158 579 2469 Antisense
ACCCGTGACTCGTCGAAATCACTTC 514 87 2485 Antisense
GAAGCTCTTCACGCTGGAACAGTCT 222 343 2518 Antisense
AACTGATGTGGCAGCTCCATTCGGT 639 141 2562 Antisense
Sequence Source Affymetrix Proprietary Database