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[192626_s_at] tyrosine-protein kinase

Description F52F12.3 /REP_DB=WormBase Gene ID /WP=CE24994 /GEN=mom-4 /TR=Q9XTC6 /GB=CAB60998.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster 6grp_highest_10_10 > 75      6grp_high1_10_10 > 56      4grp_highest_8_8 > 57      4grp_high_8_8 > 33      6grp_highest_nonorm > 83      6grp_total > 57      4grp_total > 46      6grp_highest_sub > Cu      6grp_cgc > 37      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 441
1 2 3 4 range
A 577.1
(3)
P 		418.9
(-0.7)
P 		319.5
(-3)
P 		363.2
(-2)
P 		258
B 724
(3)
P 		528
(0.3)
P 		286
(-3)
P 		282.7
(-3)
P 		441
C 582.2
(3)
P 		379.5
(-3)
P 		425.9
(-1.6)
P 		432.5
(-1.4)
P 		203
avr 627.8
(3) 		442.1
(-0.9) 		343.8
(-3) 		359.5
(-2.7) 		284

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 507
1 2 3 4 5 6 range
A 489.5
(-2)
P 		603.6
(0.1)
P 		467.7
(-2.4)
P 		433.7
(-3)
P 		442.5
(-2.8)
P 		761.2
(3)
P 		328
B 547.9
(0.4)
P 		482.7
(-1.1)
P 		561.6
(0.8)
P 		475.4
(-1.3)
P 		403.6
(-3)
P 		655.9
(3)
P 		252
C 539.1
(-0.6)
P 		507.3
(-1)
P 		534.1
(-0.6)
P 		459.7
(-1.5)
P 		334.2
(-3)
P 		841.1
(3)
P 		507
avr 525.5
(-0.8) 		531.2
(-0.7) 		521.1
(-0.9) 		456.3
(-1.9) 		393.4
(-3) 		752.7
(3) 		359
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 178
1 2 3 4 range
A 210.1
(3)
P 		90.9
(-1.6)
P 		83.5
(-1.8)
P 		53.2
(-3)
P 		157
B 230.9
(3)
P 		130.4
(-0.5)
P 		66.3
(-2.8)
P 		60.2
(-3)
P 		171
C 192.7
(3)
P 		109.1
(-1.2)
P 		148.4
(0.8)
P 		72.9
(-3)
P 		120
avr 211.2
(3) 		110.1
(-1.1) 		99.4
(-1.5) 		62.1
(-3) 		149

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 191
1 2 3 4 5 6 range
A 90.2
(-3)
P 		214.7
(3)
P 		101.8
(-2.4)
P 		110
(-2)
P 		133.5
(-0.9)
P 		185.3
(1.6)
P 		125
B 190.6
(0.3)
P 		160.7
(-1.2)
P 		136.4
(-2.5)
P 		125.9
(-3)
P 		164
(-1.1)
P 		244.6
(3)
P 		119
C 199.8
(0.4)
P 		154.8
(-1)
P 		135.9
(-1.6)
P 		92.4
(-3)
P 		108.1
(-2.5)
P 		281.6
(3)
P 		189
avr 160.2
(-0.6) 		176.7
(0.2) 		124.7
(-2.3) 		109.4
(-3) 		135.2
(-1.8) 		237.2
(3) 		128
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192626_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1348
Sequence Type Exemplar sequence
Representative Public ID F52F12.3 NCBI
Target Description F52F12.3 /REP_DB=WormBase Gene ID /WP=CE24994 /GEN=mom-4 /TR=Q9XTC6 /GB=CAB60998.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060219(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060219 NCBI Caenorhabditis elegans More Of MS family member (mom-4) (mom-4) mRNA, complete cds. 11/11 A 
SNAP00000038776 ENSEMBL cdna:SNAP chromosome:CEL140:I:9904103:9908720:-1 11/11 None
GENEFINDER00000038793 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:9904103:9908720:-1 11/11 None
F52F12.3 ENSEMBL cdna:known chromosome:CEL140:I:9903824:9908938:-1 gene:F52F12.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9904033-9908651(-) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase
Gene Symbol mom-4
Ensembl F52F12.3
Entrez Gene 172842 Entrez gene
SwissProt Q9XTC6 EMBL-EBI
WormBase CE24994 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:15748_AT protein kinase family protein at
ATH1-121501:263520_AT protein kinase family protein at
DROSOPHILA_2:1636514_AT TGF- activated kinase 1 dm
DROSGENOME1:154982_AT TGF- activated kinase 1 dm
CHICKEN:GGA.12434.1.S1_AT mitogen-activated protein kinase kinase kinase 7 gga
CHICKEN:GGA.17079.1.S1_S_AT mitogen-activated protein kinase kinase kinase 7 gga
CHICKEN:GGAAFFX.24722.1.S1_S_AT mitogen-activated protein kinase kinase kinase 7 gga
HG-U133_PLUS_2:211537_X_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133A:211537_X_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133A_2:211537_X_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133_PLUS_2:211536_X_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133A:211536_X_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133A_2:211536_X_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133_PLUS_2:206854_S_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133A:206854_S_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-FOCUS:206854_S_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133A_2:206854_S_AT mitogen-activated protein kinase kinase kinase 7 hs
HU35KSUBA:RC_AA460969_AT mitogen-activated protein kinase kinase kinase 7 hs
HU35KSUBA:AA488935_AT mitogen-activated protein kinase kinase kinase 7 hs
U133_X3P:G8978251_3P_A_AT mitogen-activated protein kinase kinase kinase 7 hs
U133_X3P:G4507360_3P_A_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U95AV2:36905_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U95B:43794_AT mitogen-activated protein kinase kinase kinase 7 hs
HG-U133_PLUS_2:206853_S_AT Mitogen-activated protein kinase kinase kinase 7 hs
HG-U133A_2:206853_S_AT Mitogen-activated protein kinase kinase kinase 7 hs
HG-U133A:206853_S_AT Mitogen-activated protein kinase kinase kinase 7 hs
HU35KSUBA:RC_D59931_S_AT Mitogen-activated protein kinase kinase kinase 7 hs
U133_X3P:HS.7510.0.S2_3P_A_AT Mitogen-activated protein kinase kinase kinase 7 hs
HG-U95B:53270_S_AT Mitogen-activated protein kinase kinase kinase 7 hs
HG-U95E:86022_AT Mitogen-activated protein kinase kinase kinase 7 hs
MOE430A:1419988_AT mitogen activated protein kinase kinase kinase 7 mm
MOUSE430_2:1419988_AT mitogen activated protein kinase kinase kinase 7 mm
MOUSE430A_2:1419988_AT mitogen activated protein kinase kinase kinase 7 mm
MOE430A:1425795_A_AT mitogen activated protein kinase kinase kinase 7 mm
MOUSE430A_2:1425795_A_AT mitogen activated protein kinase kinase kinase 7 mm
MOUSE430_2:1425795_A_AT mitogen activated protein kinase kinase kinase 7 mm
MU11KSUBA:D76446_S_AT mitogen activated protein kinase kinase kinase 7 mm
MG-U74AV2:161672_AT mitogen activated protein kinase kinase kinase 7 mm
MG-U74AV2:160854_AT mitogen activated protein kinase kinase kinase 7 mm
MOE430A:1455441_AT mitogen activated protein kinase kinase kinase 7 mm
MOUSE430A_2:1455441_AT mitogen activated protein kinase kinase kinase 7 mm
MOUSE430_2:1455441_AT mitogen activated protein kinase kinase kinase 7 mm
MOE430A:1426627_AT mitogen activated protein kinase kinase kinase 7 mm
MOUSE430A_2:1426627_AT mitogen activated protein kinase kinase kinase 7 mm
MOUSE430_2:1426627_AT mitogen activated protein kinase kinase kinase 7 mm
MG-U74BV2:108785_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
MG-U74CV2:136564_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
MOUSE430_2:1447801_X_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
MOE430B:1447801_X_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
MOUSE430_2:1449693_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
MOE430A:1449693_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
MOUSE430A_2:1449693_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
MOE430B:1458787_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
MOUSE430_2:1458787_AT Mitogen activated protein kinase kinase kinase 7, mRNA (cDNA clone MGC:5989 IMAGE:3499247) mm
RG-U34C:RC_AI146037_AT Mitogen activated protein kinase kinase kinase 7 (predicted) rn
RAE230A:1399075_AT Mitogen activated protein kinase kinase kinase 7 (predicted) rn
RAT230_2:1399075_AT Mitogen activated protein kinase kinase kinase 7 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB60998 Hypothetical protein F52F12.3 [Caenorhabditis elegans] ref|NP_492620.1| More Of MS family member (mom-4) [Caenorhabditis elegans] gb|AAD37359.1| protein kinase MOM-4 [Caenorhabditis elegans] gb|AAD39816.1| MOM-4 [Caenorhabditis elegans] 0.0
blast CAE60273 Hypothetical protein CBG03852 [Caenorhabditis briggsae] 0.0
blast T22511 hypothetical protein F52F12.3 - Caenorhabditis elegans 0.0
Protein Families
Method ID Description E-Value
hanks 2.3.1 CaMK Group; CaMK Other; MAPKAP2 8.0E-56
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.5E-46
Sequence
Target Sequence 
>C. ELEGANS:192626_S_AT
ccacatgctcatcgaccaacaatgcttggaacttcttctggaagtggaataggatcaaat
aatcgaacaccaactgcttcaaaacttttaaatcctcaacaacctggacagggtcataga
agaaatcgtagtgagacttttgtagtgcaaccggatctaccgtatccaacggttccgggt
gaagctggtgcatctagaataccaaaatctcaaagtgaagctaaaaattttcgggataga
gccaaaagcgagcaaaggcaaccacatagagacgcacgtcctcctcctccttttgagcac
cgaagagatagcaacgatgaggaaaaacatgccgtttttatgaatatttgttcgaatgag
gagactagacctattgatcctgatactcgtgacgaaaaatctttggaaatctttcatcaa
cactgtgataataataaacaatatgcagatgcttgggtcattaaaaaagaagttatgaga
gctaaacatgagctaattgcccaatggcctcaacacgatcacacggtagaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCACATGCTCATCGACCAACAATGC 332 275 1003 Antisense
AACAATGCTTGGAACTTCTTCTGGA 24 135 1020 Antisense
AATAATCGAACACCAACTGCTTCAA 579 171 1060 Antisense
AATCCTCAACAACCTGGACAGGGTC 202 167 1093 Antisense
TAGTGCAACCGGATCTACCGTATCC 628 653 1145 Antisense
CAACGGTTCCGGGTGAAGCTGGTGC 631 181 1169 Antisense
AGGCAACCACATAGAGACGCACGTC 450 53 1258 Antisense
CTCCTCCTTTTGAGCACCGAAGAGA 188 233 1286 Antisense
ATTGATCCTGATACTCGTGACGAAA 587 3 1375 Antisense
CTAATTGCCCAATGGCCTCAACACG 512 225 1495 Antisense
GCCTCAACACGATCACACGGTAGAA 540 281 1509 Antisense
Sequence Source Affymetrix Proprietary Database