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[192619_at] Protein phosphatase 2C (2 domains)

Description W09D10.4 /REP_DB=WormBase Gene ID /WP=CE16565 /TR=O18183 /GB=CAB07860.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Protein phosphatase 2C (2 domains)
Cluster 4grp_high_8_8 > 13      6grp_total > 67      4grp_total > 03      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 478
1 2 3 4 range
A 140.3
(-1.6)
P 		84.7
(-2.6)
A 		61.7
(-3)
A 		391.3
(3)
P 		330
B 108
(-2.4)
P 		72.5
(-3)
P 		71.4
(-3)
P 		469.1
(3)
P 		398
C 108.5
(-2.5)
P 		113.5
(-2.5)
P 		72.4
(-3)
A 		539.3
(3)
P 		467
avr 118.9
(-2.2) 		90.2
(-2.7) 		68.5
(-3) 		466.6
(3) 		398

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 257
1 2 3 4 5 6 range
A 80.9
(-1.7)
A 		50.2
(-2.9)
A 		47.9
(-3)
P 		54.3
(-2.7)
A 		50.8
(-2.9)
A 		201.4
(3)
P 		154
B 61
(-2.4)
P 		100.4
(-1.5)
A 		67.3
(-2.2)
A 		67.7
(-2.2)
P 		35
(-3)
A 		292
(3)
P 		257
C 58.6
(-2.9)
A 		63.3
(-2.8)
M 		60.7
(-2.9)
M 		67.1
(-2.7)
A 		56.3
(-3)
A 		291
(3)
P 		235
avr 66.8
(-2.5) 		71.3
(-2.3) 		58.6
(-2.7) 		63
(-2.6) 		47.4
(-3) 		261.5
(3) 		214
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 84
1 2 3 4 range
A 51.1
(2.1)
P 		18.4
(-2.7)
A 		16.1
(-3)
A 		57.3
(3)
P 		41
B 34.4
(-1.7)
P 		17.9
(-2.9)
P 		16.6
(-3)
P 		100
(3)
P 		83
C 35.9
(-2)
P 		32.6
(-2.3)
P 		25.3
(-3)
A 		90.9
(3)
P 		66
avr 40.5
(-1) 		23
(-2.6) 		19.3
(-3) 		82.7
(3) 		63

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 99
1 2 3 4 5 6 range
A 14.9
(-2.3)
A 		17.8
(-1.8)
A 		10.4
(-3)
P 		13.8
(-2.5)
A 		15.3
(-2.2)
A 		49
(3)
P 		39
B 21.2
(-2.6)
P 		33.4
(-1.8)
A 		16.3
(-2.9)
A 		17.9
(-2.8)
P 		14.2
(-3)
A 		108.9
(3)
P 		95
C 21.7
(-2.4)
A 		19.3
(-2.6)
M 		15.5
(-2.9)
M 		13.5
(-3)
A 		18.2
(-2.7)
A 		97.4
(3)
P 		84
avr 19.3
(-2.6) 		23.5
(-2.2) 		14.1
(-3) 		15.1
(-2.9) 		15.9
(-2.8) 		85.1
(3) 		71
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192619_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7272
Sequence Type Exemplar sequence
Representative Public ID W09D10.4 NCBI
Target Description W09D10.4 /REP_DB=WormBase Gene ID /WP=CE16565 /TR=O18183 /GB=CAB07860.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Protein phosphatase 2C (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066961(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066961 NCBI Caenorhabditis elegans W09D10.4 (W09D10.4) mRNA, complete cds. 11/11 None
SNAP00000014512 ENSEMBL cdna:SNAP chromosome:CEL140:III:10712264:10715958:-1 11/11 None
GENEFINDER00000014536 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10712264:10715958:-1 11/11 None
W09D10.4 ENSEMBL cdna:known chromosome:CEL140:III:10711442:10716068:-1 gene:W09D10.4 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10712259-10715954(-) 100.0 100.0
Public Domain and Genome References
Gene Title Protein phosphatase 2C (2 domains)
Ensembl W09D10.4
Entrez Gene 176497 Entrez gene
SwissProt O18183 EMBL-EBI
WormBase CE16565 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:267247_AT expressed protein at
CANINE:1587763_AT similar to T-cell activation protein phosphatase 2C cfa
CANINE_2:CFA.14778.1.A1_AT similar to T-cell activation protein phosphatase 2C cfa
CANINE_2:CFAAFFX.13463.1.S1_AT similar to T-cell activation protein phosphatase 2C cfa
DROSOPHILA_2:1629433_AT dm
DROSGENOME1:147984_AT dm
CHICKEN:GGA.12843.1.S1_AT T-cell activation protein phosphatase 2C gga
HU35KSUBA:AA504439_AT T-cell activation protein phosphatase 2C hs
HU35KSUBC:RC_AA521311_AT T-cell activation protein phosphatase 2C hs
HU35KSUBD:RC_T71333_AT T-cell activation protein phosphatase 2C hs
U133_X3P:HS.153089.0.A1_3P_AT T-cell activation protein phosphatase 2C hs
U133_X3P:HS.13854.0.A2_3P_AT T-cell activation protein phosphatase 2C hs
U133_X3P:HS.13854.0.A1_3P_AT T-cell activation protein phosphatase 2C hs
HG-U133_PLUS_2:225204_AT T-cell activation protein phosphatase 2C hs
HG-U133B:225204_AT T-cell activation protein phosphatase 2C hs
HG-U133_PLUS_2:225213_AT T-cell activation protein phosphatase 2C hs
HG-U133B:225213_AT T-cell activation protein phosphatase 2C hs
HG-U133_PLUS_2:235744_AT T-cell activation protein phosphatase 2C hs
HG-U133B:235744_AT T-cell activation protein phosphatase 2C hs
HG-U95C:48929_AT T-cell activation protein phosphatase 2C hs
HG-U95C:66208_AT T-cell activation protein phosphatase 2C hs
HG-U95E:83379_AT T-cell activation protein phosphatase 2C hs
HG-U95E:68599_AT T-cell activation protein phosphatase 2C hs
MU11KSUBA:AA185309_S_AT RIKEN cDNA 9130017A15 gene mm
MG-U74AV2:99503_AT RIKEN cDNA 9130017A15 gene mm
MOE430A:1455958_S_AT RIKEN cDNA 9130017A15 gene mm
MOUSE430A_2:1455958_S_AT RIKEN cDNA 9130017A15 gene mm
MOUSE430_2:1455958_S_AT RIKEN cDNA 9130017A15 gene mm
MU19KSUBA:TC17666_AT RIKEN cDNA 9130017A15 gene, mRNA (cDNA clone MGC:93006 IMAGE:30537082) mm
MU19KSUBC:TC37288_AT RIKEN cDNA 9130017A15 gene, mRNA (cDNA clone MGC:93006 IMAGE:30537082) mm
RAE230A:1375498_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAT230_2:1375498_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAE230B:1378246_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAT230_2:1378246_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAE230B:1379953_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAT230_2:1379953_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAE230A:1388522_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAT230_2:1388522_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RG-U34C:RC_AI170820_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07860 Hypothetical protein W09D10.4 [Caenorhabditis elegans] ref|NP_499362.1| W09D10.4 [Caenorhabditis elegans] 1.0E-158
blast CAE71413 Hypothetical protein CBG18323 [Caenorhabditis briggsae] 1.0E-152
blast CAB07860 Hypothetical protein W09D10.4 [Caenorhabditis elegans] ref|NP_499362.1| W09D10.4 [Caenorhabditis elegans] 1.0E-147
blast CAE71413 Hypothetical protein CBG18323 [Caenorhabditis briggsae] 1.0E-141
blast XP_624085 PREDICTED: similar to GA11388-PA [Apis mellifera] 6.0E-64
Protein Domains
Database ID Description E-Value
Pfam IPR001932 EMBL-EBI Protein phosphatase 2C-like 9.1E-4
Pfam IPR001932 EMBL-EBI Protein phosphatase 2C-like 0.0058
Pfam IPR001932 EMBL-EBI Protein phosphatase 2C-like 9.1E-4
Pfam IPR001932 EMBL-EBI Protein phosphatase 2C-like 0.0058
Sequence
Target Sequence 
>C. ELEGANS:192619_AT
catcggcattctcgcggaggttaatgaaagaatgtgaaaaacgtgttcagaaaggagatt
tcgatccacaaaagcctgaatctctcctggactatgctttcagagcatctgcagaggcgc
cgaggcctgttggatcctcaacagcatgcgttcttgtcgtccatcaagaaaagttgtatt
cggcgaatctgggggattctggatttatggttgttcgcaatggaaagattgtatcaaaaa
gtcgtgaacaagtgcattatttcaatgcaccattccaattaacacttccaccagaaggat
atcaaggatttattggtgataaggctgatatggctgataaagatgagatggctgttaaga
agggtgatattattctattagcaactgatggtgtatgggataatcttagtgagcaacagg
tgctcgatcagctgaaagctcttgatgctggaaagagtaatgtgcaagaggtatgcaatg
ctctggcactgaccgcccgtcgattagcattcgactcaaaacacaacagcccatttgcaa
tgaaggctcgtgaacacggattcttggcgccaggcggaaaaccagatgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATCGGCATTCTCGCGGAGGTTAAT 693 209 386 Antisense
TCCACAAAAGCCTGAATCTCTCCTG 517 587 450 Antisense
GAATCTCTCCTGGACTATGCTTTCA 174 329 463 Antisense
TTCAGAGCATCTGCAGAGGCGCCGA 161 685 484 Antisense
GTTGGATCCTCAACAGCATGCGTTC 196 437 514 Antisense
CATTCCAATTAACACTTCCACCAGA 361 13 656 Antisense
AGCAACAGGTGCTCGATCAGCTGAA 159 77 797 Antisense
GGTATGCAATGCTCTGGCACTGACC 230 503 855 Antisense
ACCGCCCGTCGATTAGCATTCGACT 702 89 877 Antisense
GCTCGTGAACACGGATTCTTGGCGC 172 299 931 Antisense
GGCGCCAGGCGGAAAACCAGATGAT 200 543 951 Antisense
Sequence Source Affymetrix Proprietary Database