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[192616_at] serine/threonine kinase

Description W06F12.3 /REP_DB=WormBase Gene ID /WP=CE16557 /GEN=lit-1 /TR=O45897 /GB=CAB05829.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 26      4grp_total > 15      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 38
1 2 3 4 range
A 18
(-0.7)
A 		3.9
(-3)
A 		39.9
(3)
A 		8.4
(-2.3)
A 		36
B 23.9
(1.4)
A 		26.3
(1.9)
A 		2.2
(-3)
A 		31.6
(3)
A 		29
C 39.3
(3)
A 		9.5
(-3)
A 		15.8
(-1.7)
A 		38
(2.7)
A 		30
avr 27.1
(3) 		13.2
(-3) 		19.3
(-0.4) 		26
(2.5) 		14

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 53
1 2 3 4 5 6 range
A 39.6
(3)
A 		23.1
(-0.1)
A 		15.2
(-1.6)
A 		26.7
(0.5)
A 		28.8
(0.9)
A 		8.1
(-3)
A 		32
B 36.6
(3)
A 		28.6
(1.6)
A 		33
(2.4)
A 		2.8
(-3)
A 		30.7
(2)
A 		23.5
(0.7)
A 		34
C 11
(-2.1)
A 		55.6
(3)
A 		14.5
(-1.7)
A 		3.1
(-3)
A 		7.6
(-2.5)
A 		38.1
(1)
A 		53
avr 29.1
(1.4) 		35.8
(3) 		20.9
(-0.6) 		10.9
(-3) 		22.4
(-0.2) 		23.2
(-0) 		25
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 6.6
(0.6)
A 		0.8
(-3)
A 		10.4
(3)
A 		1.2
(-2.8)
A 		10
B 7.6
(3)
A 		6.5
(2.1)
A 		0.5
(-3)
A 		6.7
(2.2)
A 		7
C 13
(3)
A 		2.7
(-3)
A 		5.5
(-1.4)
A 		6.4
(-0.8)
A 		10
avr 9.1
(3) 		3.3
(-3) 		5.5
(-0.7) 		4.8
(-1.4) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 7.3
(1.7)
A 		8.2
(2.6)
A 		3.3
(-1.8)
A 		6.8
(1.3)
A 		8.7
(3)
A 		2
(-3)
A 		7
B 12.7
(3)
A 		9.5
(1.4)
A 		8
(0.7)
A 		0.7
(-3)
A 		12.5
(2.9)
A 		8.7
(1)
A 		12
C 4.1
(-1.7)
A 		17
(3)
A 		3.7
(-1.9)
A 		0.6
(-3)
A 		2.5
(-2.3)
A 		12.8
(1.5)
A 		16
avr 8
(0.6) 		11.6
(3) 		5
(-1.4) 		2.7
(-3) 		7.9
(0.5) 		7.8
(0.4) 		9
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192616_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8028
Sequence Type Exemplar sequence
Representative Public ID W06F12.3 NCBI
Target Description W06F12.3 /REP_DB=WormBase Gene ID /WP=CE16557 /GEN=lit-1 /TR=O45897 /GB=CAB05829.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067434(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067434 NCBI Caenorhabditis elegans W06F12.3 (W06F12.3) mRNA, complete cds. 11/11 None
SNAP00000027466 ENSEMBL cdna:SNAP chromosome:CEL140:III:13734808:13736008:1 11/11 None
W06F12.3 ENSEMBL cdna:known chromosome:CEL140:III:13734587:13736008:1 gene:W06F12.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000027467 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:13734582-13736004(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl W06F12.3
Entrez Gene 189253 Entrez gene
SwissProt O45897 EMBL-EBI
WormBase CE16557 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05829 Hypothetical protein W06F12.3 [Caenorhabditis elegans] ref|NP_499835.1| W06F12.3 [Caenorhabditis elegans] 1.0E-174
blast CAB05829 Hypothetical protein W06F12.3 [Caenorhabditis elegans] ref|NP_499835.1| W06F12.3 [Caenorhabditis elegans] 1.0E-140
blast CAE71382 Hypothetical protein CBG18289 [Caenorhabditis briggsae] 1.0E-111
blast CAE71382 Hypothetical protein CBG18289 [Caenorhabditis briggsae] 6.0E-92
blast CAA91303 Hypothetical protein T05C12.1 [Caenorhabditis elegans] ref|NP_495715.1| T05C12.1 [Caenorhabditis elegans] 6.0E-68
blast CAA91303 Hypothetical protein T05C12.1 [Caenorhabditis elegans] ref|NP_495715.1| T05C12.1 [Caenorhabditis elegans] 1.0E-54
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.4E-25
Pfam IPR000719 EMBL-EBI Protein kinase 2.2E-16
Sequence
Target Sequence 
>C. ELEGANS:192616_AT
atcacagaccttcgaaagttccagaagggacggtgtttttctgctgaaacgacggcgaga
gtaggaattcaatgtttggagggattgaagcagattcacgagctaggatatattcataga
gacattaaaccttcgaacatctgtgtgggcattggtgagcacaagcgggtcctctacatt
gtcgattttggaatggctcgtcagattcgctttcccagtggcgcttttcgaccggaacgc
ccgtacgcctcattccgtggtactactcgatacgtttccctggcagctcatgaacggaaa
gagcaaggttttgcagatgatatttggtgcctattcttctcacttttggagttagccgag
ggacttccttggaaaaacgtggtggatcaggatcaggtttaccatgccaaacagcttttg
ttgaggaactttcaatcaaggaaaatgggtcaaaacttcgggacatttcctcgagccctc
gagctcatcaaacggacagaaactccaaattatgagaatttcatcgttattctgaaatcc
tgcagttcgcgtgtcaatgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCACAGACCTTCGAAAGTTCCAGA 548 27 364 Antisense
GAAGGGACGGTGTTTTTCTGCTGAA 521 333 387 Antisense
AACCTTCGAACATCTGTGTGGGCAT 677 147 491 Antisense
ATTGGTGAGCACAAGCGGGTCCTCT 667 3 514 Antisense
CTCATTCCGTGGTACTACTCGATAC 80 229 612 Antisense
TTTCCCTGGCAGCTCATGAACGGAA 358 669 638 Antisense
TATTTGGTGCCTATTCTTCTCACTT 596 661 684 Antisense
TGGAGTTAGCCGAGGGACTTCCTTG 279 547 710 Antisense
CAAAACTTCGGGACATTTCCTCGAG 89 189 814 Antisense
CCCTCGAGCTCATCAAACGGACAGA 316 259 839 Antisense
ATCCTGCAGTTCGCGTGTCAATGAA 407 39 900 Antisense
Sequence Source Affymetrix Proprietary Database