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[192614_at] aromatic-L-amino-acid decarboxylase

Description C09G9.4 /REP_DB=WormBase Gene ID /WP=CE03003 /TR=Q17874 /GB=CAA90974.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=aromatic-L-amino-acid decarboxylase
Cluster 6grp_total > 98      4grp_total > 18      6grp_cgc > 69      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 147
1 2 3 4 range
A 29.8
(-2.8)
A 		25.6
(-3)
A 		33.7
(-2.6)
A 		145.9
(3)
P 		120
B 22.2
(-3)
A 		63.7
(1.9)
A 		48.8
(0.2)
A 		72.8
(3)
A 		51
C 30.6
(-2.2)
A 		67.3
(-0.7)
A 		10.2
(-3)
A 		157.1
(3)
P 		147
avr 27.5
(-3) 		52.2
(-1.5) 		30.9
(-2.8) 		125.3
(3) 		98

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 116
1 2 3 4 5 6 range
A 28
(-2.4)
A 		16.8
(-3)
A 		65.9
(-0.2)
A 		39
(-1.7)
A 		107.8
(2.2)
A 		121.6
(3)
A 		105
B 40.3
(-1.5)
A 		37.8
(-1.7)
A 		20.5
(-3)
A 		51.8
(-0.6)
A 		97.6
(2.8)
P 		100.3
(3)
P 		80
C 26.4
(-1.7)
A 		33.8
(-1.2)
A 		5.6
(-3)
A 		41.6
(-0.7)
A 		69.5
(1.1)
A 		100.1
(3)
P 		95
avr 31.6
(-2.8) 		29.5
(-3) 		30.7
(-2.9) 		44.1
(-1.9) 		91.6
(1.8) 		107.3
(3) 		78
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 10.9
(-1)
A 		5.6
(-3)
A 		8.8
(-1.8)
A 		21.4
(3)
P 		16
B 7.1
(-3)
A 		15.7
(3)
A 		11.3
(-0.1)
A 		15.5
(2.9)
A 		9
C 10.1
(-1.3)
A 		19.3
(1.1)
A 		3.5
(-3)
A 		26.5
(3)
P 		23
avr 9.4
(-2.3) 		13.5
(-0.5) 		7.9
(-3) 		21.1
(3) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 38
1 2 3 4 5 6 range
A 5.2
(-3)
A 		6
(-2.8)
A 		14.3
(-1)
A 		9.9
(-2)
A 		32.5
(3)
A 		29.6
(2.4)
A 		27
B 14
(-1.4)
A 		12.6
(-1.7)
A 		5
(-3)
A 		13.7
(-1.5)
A 		39.6
(3)
P 		37.4
(2.6)
P 		35
C 9.8
(-1.4)
A 		10.3
(-1.3)
A 		1.4
(-3)
A 		8.4
(-1.7)
A 		22.5
(0.9)
A 		33.5
(3)
P 		32
avr 9.7
(-2.4) 		9.6
(-2.4) 		6.9
(-3) 		10.7
(-2.1) 		31.5
(2.5) 		33.5
(3) 		27
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192614_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9523
Sequence Type Exemplar sequence
Representative Public ID C09G9.4 NCBI
Target Description C09G9.4 /REP_DB=WormBase Gene ID /WP=CE03003 /TR=Q17874 /GB=CAA90974.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=aromatic-L-amino-acid decarboxylase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069138(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069138 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-19) (tag-19) mRNA, complete cds. 11/11 None
SNAP00000008790 ENSEMBL cdna:SNAP chromosome:CEL140:IV:8874252:8876958:1 11/11 None
GENEFINDER00000008803 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:8874252:8876958:1 11/11 None
C09G9.4 ENSEMBL cdna:known chromosome:CEL140:IV:8874665:8876958:1 gene:C09G9.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:8874670-8876964(+) 99.42 100.0
Public Domain and Genome References
Gene Title aromatic-L-amino-acid decarboxylase
Gene Symbol tag-19
Ensembl C09G9.4
Entrez Gene 182464 Entrez gene
SwissProt Q17874 EMBL-EBI
WormBase CE35390 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6520 amino acid metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16831 carboxy-lyase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90974 Hypothetical protein C09G9.4 [Caenorhabditis elegans] ref|NP_501539.2| Temporarily Assigned Gene name family member (tag-19) [Caenorhabditis elegans] 0.0
blast CAE71099 Hypothetical protein CBG17950 [Caenorhabditis briggsae] 0.0
blast AAP34326 histidine decarboxylase [Aplysia californica] 2.0E-24
blast AAP34326 histidine decarboxylase [Aplysia californica] 4.0E-24
Protein Domains
Database ID Description E-Value
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 8.5E-4
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 6.7E-7
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 0.14
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 8.5E-4
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 6.7E-7
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 8.5E-4
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 6.7E-7
Pfam IPR002129 EMBL-EBI Pyridoxal-dependent decarboxylase 0.35
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000008790 1 5-27
GENEFINDER00000008803 1 5-27
Sequence
Target Sequence 
>C. ELEGANS:192614_AT
gtgcacattacatgttcatccctgttcccgtattctggaagaatttcagttgtttggagt
tgtgagaaattggagttggatggagccaagatcctttatggagaacacccaattcgttta
tggattctcattcgtctccatggtatccgatcaattcgtgaagctgtcaagcgaaagatt
attcttgggaacgctttctctgagaggatgtcacatcattcacagttattcgagatgcat
cataccaatgaacatggagttacagtttttcagtataaaaataaaaaaatcaaagatcgc
actgaggatacaaataagattacttcaatgttccacaactatctcgtcttgtcctcaact
ctcaagttctcaattgtttcgttccacggaaaagtcctcatcaagtcagttgtcaactac
ggtcgatgcaacctctcaatcatggacgagtctgtctcgactttggtga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGCACATTACATGTTCATCCCTGT 433 481 934 Antisense
ATCCCTGTTCCCGTATTCTGGAAGA 435 37 951 Antisense
TCATTCGTCTCCATGGTATCCGATC 137 619 1061 Antisense
ATTCTTGGGAACGCTTTCTCTGAGA 644 11 1114 Antisense
GTCACATCATTCACAGTTATTCGAG 241 465 1143 Antisense
TCAATGTTCCACAACTATCTCGTCT 436 633 1258 Antisense
CAAGTTCTCAATTGTTTCGTTCCAC 56 185 1296 Antisense
GAAAAGTCCTCATCAAGTCAGTTGT 63 355 1322 Antisense
GTCAACTACGGTCGATGCAACCTCT 220 463 1345 Antisense
GCAACCTCTCAATCATGGACGAGTC 168 321 1361 Antisense
GACGAGTCTGTCTCGACTTTGGTGA 305 379 1378 Antisense
Sequence Source Affymetrix Proprietary Database