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[192599_at] serine/threonine kinase (2 domains)

Description C49C3.2 /REP_DB=WormBase Gene ID /WP=CE19741 /TR=Q9XUG0 /GB=CAB05158.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase (2 domains)
Cluster 6grp_total > 99      4grp_total > 37      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 41
1 2 3 4 range
A 39
(3)
A 		29.8
(1.5)
A 		2.5
(-3)
A 		8.4
(-2)
A 		37
B 23.7
(0.4)
A 		33.5
(3)
A 		17.6
(-1.2)
A 		10.8
(-3)
A 		23
C 20.9
(-0.6)
A 		5.8
(-3)
A 		18.3
(-1)
A 		43.3
(3)
A 		38
avr 27.9
(3) 		23
(1.1) 		12.8
(-3) 		20.8
(0.2) 		15

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 51
1 2 3 4 5 6 range
A 6.5
(-2.3)
A 		6.2
(-2.4)
A 		2.4
(-3)
A 		8.4
(-2)
A 		30.4
(1.6)
A 		39.3
(3)
A 		37
B 37
(1)
A 		3.7
(-2.9)
A 		33.3
(0.6)
A 		2.8
(-3)
A 		33.9
(0.7)
A 		53.5
(3)
A 		51
C 3.9
(-3)
A 		5.6
(-2.8)
A 		25.8
(-0.1)
A 		7.3
(-2.5)
A 		49.2
(3)
A 		41.1
(1.9)
A 		45
avr 15.8
(-1.4) 		5.2
(-3) 		20.5
(-0.7) 		6.2
(-2.8) 		37.8
(2) 		44.6
(3) 		39
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 14.2
(3)
A 		6.5
(-0.4)
A 		0.6
(-3)
A 		1.2
(-2.7)
A 		14
B 7.6
(2.3)
A 		8.3
(3)
A 		4.1
(-1.2)
A 		2.3
(-3)
A 		6
C 6.9
(2.6)
A 		1.7
(-3)
A 		6.4
(2)
A 		7.3
(3)
A 		6
avr 9.6
(3) 		5.5
(-1.1) 		3.7
(-2.9) 		3.6
(-3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 19
1 2 3 4 5 6 range
A 1.2
(-2.5)
A 		2.2
(-1.9)
A 		0.5
(-3)
A 		2.1
(-1.9)
A 		9.2
(2.7)
A 		9.6
(3)
A 		9
B 12.9
(0.8)
A 		1.2
(-2.8)
A 		8.1
(-0.7)
A 		0.7
(-3)
A 		13.8
(1.1)
A 		19.9
(3)
A 		19
C 1.5
(-3)
A 		1.7
(-2.9)
A 		6.6
(-0.9)
A 		1.5
(-3)
A 		15.9
(3)
A 		13.8
(2.1)
A 		14
avr 5.2
(-1.2) 		1.7
(-2.9) 		5.1
(-1.3) 		1.4
(-3) 		13
(2.4) 		14.4
(3) 		13
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192599_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10108
Sequence Type Exemplar sequence
Representative Public ID C49C3.2 NCBI
Target Description C49C3.2 /REP_DB=WormBase Gene ID /WP=CE19741 /TR=Q9XUG0 /GB=CAB05158.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070677(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070677 NCBI Caenorhabditis elegans C49C3.2 (C49C3.2) mRNA, complete cds. 10/11 None
SNAP00000040192 ENSEMBL cdna:SNAP chromosome:CEL140:IV:17316665:17318201:1 11/11 None
C49C3.2 ENSEMBL cdna:known chromosome:CEL140:IV:17316665:17318175:1 gene:C49C3.2 10/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000040213 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:17316670-17318207(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase (2 domains)
Ensembl C49C3.2
Entrez Gene 183596 Entrez gene
SwissProt Q9XUG0 EMBL-EBI
WormBase CE36280 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05158 Hypothetical protein C49C3.2 [Caenorhabditis elegans] ref|NP_503078.2| C49C3.2 [Caenorhabditis elegans] 1.0E-173
blast CAB05158 Hypothetical protein C49C3.2 [Caenorhabditis elegans] ref|NP_503078.2| C49C3.2 [Caenorhabditis elegans] 1.0E-170
blast AAB37560 Hypothetical protein C09B9.4 [Caenorhabditis elegans] ref|NP_500708.1| C09B9.4 [Caenorhabditis elegans] 1.0E-135
blast CAE72809 Hypothetical protein CBG20086 [Caenorhabditis briggsae] 1.0E-134
blast CAE72809 Hypothetical protein CBG20086 [Caenorhabditis briggsae] 1.0E-128
blast AAB37560 Hypothetical protein C09B9.4 [Caenorhabditis elegans] ref|NP_500708.1| C09B9.4 [Caenorhabditis elegans] 1.0E-127
Sequence
Target Sequence 
>C. ELEGANS:192599_AT
gcacttcaaacattagaccgtctccgcgtgcttcatcatgccgggtggctaaatcgagat
gttaaagctcagaattttgcggtaggatttggagaagagagcaatattgtgtatatgctg
gattttggtttgaccagaagatttttagaactggacgggagtcgccaccttctccgtccc
tggggtccttcggttggcacattcccctatgctccactgagctctcttggatttctagat
caaactccagctgatgatgttgaaggctggctttacatgataattcacttgctaaacggt
ctaccttggcacaattccaaaagatcgctaagtctcgcaaaagttcgagaatggaagatg
tattgtcgacgagctggaggcagaacacaacttttccgagatattccggatggctggtct
gatgtttttgatattattctgaaaacttcttatcaagaatacccagattacaccaaaatt
ttgaataaagtcatgtcgatgctcgtaaatccagtgcttcgttcactggtccgtctaggt
ccattgagctgtgacgagctgacttctcaaac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCACTTCAAACATTAGACCGTCTCC 496 315 388 Antisense
TGCTTCATCATGCCGGGTGGCTAAA 472 579 416 Antisense
TTAGAACTGGACGGGAGTCGCCACC 262 677 532 Antisense
CACTGAGCTCTCTTGGATTTCTAGA 230 199 602 Antisense
AATTCACTTGCTAAACGGTCTACCT 595 173 669 Antisense
CGGTCTACCTTGGCACAATTCCAAA 459 243 684 Antisense
GAGGCAGAACACAACTTTTCCGAGA 292 403 764 Antisense
TATTCCGGATGGCTGGTCTGATGTT 387 665 789 Antisense
TGCTCGTAAATCCAGTGCTTCGTTC 288 581 887 Antisense
GTCCGTCTAGGTCCATTGAGCTGTG 337 475 916 Antisense
GCTGTGACGAGCTGACTTCTCAAAC 160 295 935 Antisense
Sequence Source Affymetrix Proprietary Database