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[192571_s_at]

Description C51E3.7B /REP_DB=WormBase Gene ID /WP=CE08941 /GEN=egl-3 /TR=Q18772 /GB=CAB01642.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=prohormone convertase 2
Cluster 6grp_highest_10_10 > 31      6grp_high1_10_10 > 13      4grp_highest_8_8 > 53      4grp_high_8_8 > 09      6grp_highest_nonorm > 14      6grp_total > 14      4grp_total > 30      6grp_highest_sub > De      6grp_cgc > 30      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 6121
1 2 3 4 range
A 7138.2
(3)
P 		2375.5
(-2.2)
P 		1668
(-3)
P 		5295.4
(1)
P 		5470
B 7481.7
(3)
P 		2552.4
(-2.3)
P 		1922.2
(-3)
P 		6468.4
(1.9)
P 		5560
C 7789.2
(3)
P 		2851.4
(-2.1)
P 		1982.3
(-3)
P 		5203.9
(0.3)
P 		5807
avr 7469.7
(3) 		2593.1
(-2.2) 		1857.5
(-3) 		5655.9
(1.1) 		5612

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3468
1 2 3 4 5 6 range
A 3993
(-0.3)
P 		5523.6
(3)
P 		3007.4
(-2.5)
P 		3326.1
(-1.8)
P 		2761.7
(-3)
P 		3574.4
(-1.2)
P 		2762
B 4642
(3)
P 		3949.3
(1.2)
P 		3535.2
(0.1)
P 		3779.4
(0.8)
P 		2506.2
(-2.5)
P 		2315.3
(-3)
P 		2327
C 5672.1
(3)
P 		3644.2
(-0.5)
P 		4204.9
(0.5)
P 		3375.3
(-1)
P 		3024.1
(-1.6)
P 		2203.7
(-3)
P 		3468
avr 4769
(3) 		4372.4
(1.9) 		3582.5
(-0.4) 		3493.6
(-0.7) 		2764
(-2.8) 		2697.8
(-3) 		2071
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2163
1 2 3 4 range
A 2599
(3)
P 		515.7
(-2.8)
P 		436
(-3)
P 		775.1
(-2.1)
P 		2163
B 2385.9
(3)
P 		630.4
(-2.4)
P 		445.4
(-3)
P 		1378.4
(-0.1)
P 		1941
C 2578.4
(3)
P 		819.8
(-2.6)
P 		690.9
(-3)
P 		877.5
(-2.4)
P 		1888
avr 2521.1
(3) 		655.3
(-2.6) 		524.1
(-3) 		1010.3
(-1.5) 		1997

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1448
1 2 3 4 5 6 range
A 736.1
(-2.6)
P 		1964.4
(3)
P 		654.9
(-3)
P 		843.6
(-2.1)
P 		833.4
(-2.2)
P 		870.3
(-2)
P 		1310
B 1615.2
(3)
P 		1314.6
(0.6)
P 		858.4
(-3)
P 		1001
(-1.9)
P 		1018.2
(-1.7)
P 		863.4
(-3)
P 		757
C 2102.4
(3)
P 		1111.9
(-1.2)
P 		1070.2
(-1.4)
P 		678.8
(-3)
P 		978.5
(-1.7)
P 		737.7
(-2.8)
P 		1424
avr 1484.6
(3) 		1463.6
(2.8) 		861.2
(-2.7) 		841.1
(-2.8) 		943.4
(-1.9) 		823.8
(-3) 		661
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192571_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11609
Sequence Type Exemplar sequence
Representative Public ID C51E3.7B NCBI
Target Description C51E3.7B /REP_DB=WormBase Gene ID /WP=CE08941 /GEN=egl-3 /TR=Q18772 /GB=CAB01642.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=prohormone convertase 2
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073213(11), NM_001028561(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073213 NCBI Caenorhabditis elegans EGg Laying defective family member (egl-3) (egl-3) mRNA, complete cds. 11/11 A 
NM_001028561 NCBI Caenorhabditis elegans EGg Laying defective family member (egl-3) (egl-3) mRNA, complete cds. 11/11 None
SNAP00000031204 ENSEMBL cdna:SNAP chromosome:CEL140:V:10172361:10176331:-1 11/11 None
GENEFINDER00000031206 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10172361:10176333:-1 11/11 None
C51E3.7b.2 ENSEMBL cdna:known chromosome:CEL140:V:10171547:10176335:-1 gene:C51E3.7 11/11 None
C51E3.7b.1 ENSEMBL cdna:known chromosome:CEL140:V:10171777:10176335:-1 gene:C51E3.7 11/11 A 
C51E3.7a.3 ENSEMBL cdna:known chromosome:CEL140:V:10171839:10176335:-1 gene:C51E3.7 11/11 None
C51E3.7a.1 ENSEMBL cdna:known chromosome:CEL140:V:10171839:10176333:-1 gene:C51E3.7 11/11 None
C51E3.7a.2 ENSEMBL cdna:known chromosome:CEL140:V:10172361:10176335:-1 gene:C51E3.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10172360-10176331(-) 100.0 100.0
Public Domain and Genome References
Ensembl C51E3.7
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB01642 Hypothetical protein C51E3.7b [Caenorhabditis elegans] ref|NP_505614.3| EGg Laying defective family member (egl-3) [Caenorhabditis elegans] 0.0
blast CAE64748 Hypothetical protein CBG09536 [Caenorhabditis briggsae] 0.0
blast CAB01635 Hypothetical protein C51E3.7a [Caenorhabditis elegans] ref|NP_001023732.1| EGg Laying defective family member (egl-3) [Caenorhabditis elegans] gb|AAA56868.1| prohormone convertase 2 [Caenorhabditis elegans] 0.0
blast ABA29807 convertase 2 precursor [Brugia malayi] 0.0
blast AAK66762 proprotein convertase 2 [Heterodera glycines] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 2.9E-76
Pfam IPR000209 EMBL-EBI Peptidase S8 and S53, subtilisin, kexin, sedolisin 1.5E-88
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 2.9E-76
Pfam IPR000209 EMBL-EBI Peptidase S8 and S53, subtilisin, kexin, sedolisin 1.6E-109
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 2.9E-76
Pfam IPR000209 EMBL-EBI Peptidase S8 and S53, subtilisin, kexin, sedolisin 1.6E-109
Sequence
Target Sequence 
>C. ELEGANS:192571_S_AT
cgcgactctcatggaaactgttctcactttgaatggcaaatgaatggagttggactcgag
tacaatcaccttttcggatttggagttcttgatgcagcagagatggtcatgttggcaatg
gcctggaagacttccccaccacgttatcactgtactgctggactcattgacactccacat
gagatcccagccgatggaaacttgattcttgaaattaatactgatggatgtgccggatct
caattcgaagtccgctacctggaacatgttcaagcagttgtctcgttcaactcgactcgt
cgtggagataccactctctacttgatctctccaatgggaacccgtaccatgattctttcc
cgcagaccaaaggatgatgattcaaaggatggattcaccaactggccattcatgacaaca
cacacatggggagagaatccaacaggaaaatggagacttgtcgccagattccaaggacct
ggagctcatgccggaacccttaagaagttcgagctgatgttgcacggaacaagagaagcc
ccatacaatctcatcgagccaatcgtcggtc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGCGACTCTCATGGAAACTGTTCTC 7 257 1060 Antisense
TGGACTCGAGTACAATCACCTTTTC 275 547 1110 Antisense
CAATGGCCTGGAAGACTTCCCCACC 79 183 1175 Antisense
ACGTTATCACTGTACTGCTGGACTC 450 93 1200 Antisense
GATGGATGTGCCGGATCTCAATTCG 510 407 1282 Antisense
GAAGTCCGCTACCTGGAACATGTTC 306 335 1306 Antisense
CTCGTTCAACTCGACTCGTCGTGGA 335 231 1341 Antisense
GAGATACCACTCTCTACTTGATCTC 331 397 1364 Antisense
GATCTCTCCAATGGGAACCCGTACC 217 417 1383 Antisense
AGCTCATGCCGGAACCCTTAAGAAG 677 77 1542 Antisense
AATCTCATCGAGCCAATCGTCGGTC 372 169 1606 Antisense
Sequence Source Affymetrix Proprietary Database