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[192557_s_at] glutamate receptor subunit epsilon

Description T01C3.10 /REP_DB=WormBase Gene ID /WP=CE12926 /TR=Q22063 /GB=CAB01667.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=glutamate receptor subunit epsilon
Cluster 6grp_total > 51      4grp_total > 21      6grp_cgc > 83      6grp_cgc_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 268
1 2 3 4 range
A 201.9
(0)
P 		158.7
(-1.1)
A 		89.8
(-3)
A 		312.3
(3)
A 		223
B 206.6
(3)
P 		112.6
(-0.5)
A 		44.2
(-3)
A 		138.4
(0.5)
M 		162
C 170.9
(0.3)
P 		116.5
(-2)
A 		93.6
(-3)
A 		236.2
(3)
P 		143
avr 193.1
(1.6) 		129.3
(-0.9) 		75.9
(-3) 		229
(3) 		153

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 102
1 2 3 4 5 6 range
A 175.7
(2.1)
A 		130
(-1.2)
A 		167.9
(1.5)
A 		188.5
(3)
P 		115.7
(-2.2)
A 		104.1
(-3)
A 		84
B 116.5
(-0.4)
A 		122.6
(0.8)
A 		115.4
(-0.6)
P 		133.2
(3)
A 		130.9
(2.5)
A 		103.8
(-3)
A 		29
C 119.2
(-0.7)
A 		141.1
(0.9)
M 		169.7
(3)
P 		153.8
(1.8)
A 		108.6
(-1.4)
A 		86.8
(-3)
M 		83
avr 137.1
(0.9) 		131.2
(0.3) 		151
(2.3) 		158.5
(3) 		118.4
(-1) 		98.2
(-3) 		60
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 63
1 2 3 4 range
A 73.5
(3)
P 		34.4
(-1.7)
A 		23.5
(-3)
A 		45.7
(-0.3)
A 		50
B 65.9
(3)
P 		27.8
(-1.1)
A 		10.2
(-3)
A 		29.5
(-0.9)
M 		56
C 56.6
(3)
P 		33.5
(-2.8)
A 		32.6
(-3)
A 		39.8
(-1.2)
P 		24
avr 65.3
(3) 		31.9
(-1.6) 		22.1
(-3) 		38.3
(-0.8) 		43

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 28
1 2 3 4 5 6 range
A 32.4
(-1.1)
A 		46.2
(2.6)
A 		36.6
(0)
A 		47.8
(3)
P 		34.9
(-0.4)
A 		25.3
(-3)
A 		23
B 40.5
(-0)
A 		40.8
(0)
A 		28
(-3)
P 		35.3
(-1.3)
A 		53.2
(3)
A 		38.7
(-0.5)
A 		25
C 44.2
(3)
A 		43.1
(2.6)
M 		43.2
(2.6)
P 		30.9
(-2.3)
A 		35.1
(-0.6)
A 		29
(-3)
M 		15
avr 39
(0.9) 		43.4
(3) 		35.9
(-0.6) 		38
(0.4) 		41.1
(1.9) 		31
(-3) 		12
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192557_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12556
Sequence Type Exemplar sequence
Representative Public ID T01C3.10 NCBI
Target Description T01C3.10 /REP_DB=WormBase Gene ID /WP=CE12926 /TR=Q22063 /GB=CAB01667.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=glutamate receptor subunit epsilon
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074293(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074293 NCBI Caenorhabditis elegans NMDA class glutamate receptor family member (nmr-2) (nmr-2) mRNA, complete cds. 11/11 None
GENEFINDER00000022431 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:15008998:15010477:-1 11/11 None
T01C3.10 ENSEMBL cdna:known chromosome:CEL140:V:15008998:15013534:-1 gene:T01C3.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15008997-15013534(-) 100.0 100.0
Public Domain and Genome References
Gene Title glutamate receptor subunit epsilon
Gene Symbol nmr-2
Ensembl T01C3.10
Entrez Gene 180002 Entrez gene
SwissProt Q22063 EMBL-EBI
WormBase CE30445 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.16222.1.S1_S_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B cfa
DROSGENOME1:144062_AT NMDA receptor 2 dm
DROSOPHILA_2:1640464_AT NMDA receptor 2 dm
CHICKEN:GGAAFFX.7496.1.S1_AT similar to Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D-aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3) gga
HG-U95AV2:32489_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U133_PLUS_2:210412_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U133A:210412_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-FOCUS:210412_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U133A_2:210412_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U133_PLUS_2:210411_S_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U133A:210411_S_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U133A_2:210411_S_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HUGENEFL:U28758_S_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HUGENEFL:U11287_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
U133_X3P:G560546_3P_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
U133_X3P:G1899201_3P_A_AT glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U133_PLUS_2:237933_AT Glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U133B:237933_AT Glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U95B:48207_AT Glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U95E:84599_AT Glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HG-U95D:86873_AT Glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
HU35KSUBD:RC_AA199659_AT Glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
U133_X3P:HS.170561.0.A1_3P_AT Glutamate receptor, ionotropic, N-methyl D-aspartate 2B hs
MOUSE430A_2:1431700_AT glutamate receptor, ionotropic, NMDA2B (epsilon 2) mm
MOE430A:1431700_AT glutamate receptor, ionotropic, NMDA2B (epsilon 2) mm
MOUSE430_2:1431700_AT glutamate receptor, ionotropic, NMDA2B (epsilon 2) mm
MOE430A:1422223_AT glutamate receptor, ionotropic, NMDA2B (epsilon 2) mm
MOUSE430A_2:1422223_AT glutamate receptor, ionotropic, NMDA2B (epsilon 2) mm
MOUSE430_2:1422223_AT glutamate receptor, ionotropic, NMDA2B (epsilon 2) mm
MU11KSUBB:MSA.17.0_AT glutamate receptor, ionotropic, NMDA2B (epsilon 2) mm
MG-U74AV2:101312_AT glutamate receptor, ionotropic, NMDA2B (epsilon 2) mm
RN-U34:U11419_AT glutamate receptor, ionotropic, NMDA2B rn
RG-U34A:U11419_AT glutamate receptor, ionotropic, NMDA2B rn
RAE230A:1369745_AT glutamate receptor, ionotropic, NMDA2B rn
RAT230_2:1369745_AT glutamate receptor, ionotropic, NMDA2B rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4872 receptor activity inferred from electronic annotation QuickGO AmiGO
4970 ionotropic glutamate receptor activity inferred from electronic annotation QuickGO AmiGO
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
5234 glutamate-gated ion channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01667 Hypothetical protein T01C3.10 [Caenorhabditis elegans] emb|CAB02939.2| Hypothetical protein T01C3.10 [Caenorhabditis elegans] ref|NP_506694.2| NMDA class glutamate receptor family member (nmr-2) [Caenorhabditis elegans] 0.0
blast CAE66334 Hypothetical protein CBG11585 [Caenorhabditis briggsae] 0.0
blast AAK01102 ionotropic glutamate receptor NMR-2 [Caenorhabditis elegans] 0.0
blast CAB01667 Hypothetical protein T01C3.10 [Caenorhabditis elegans] emb|CAB02939.2| Hypothetical protein T01C3.10 [Caenorhabditis elegans] ref|NP_506694.2| NMDA class glutamate receptor family member (nmr-2) [Caenorhabditis elegans] 1.0E-179
blast CAE66334 Hypothetical protein CBG11585 [Caenorhabditis briggsae] 1.0E-168
blast AAK01102 ionotropic glutamate receptor NMR-2 [Caenorhabditis elegans] 1.0E-122
Protein Domains
Database ID Description E-Value
Pfam IPR001320 EMBL-EBI Ionotropic glutamate receptor 1.6E-77
Pfam IPR001828 EMBL-EBI Extracellular ligand-binding receptor 1.0E-10
Pfam IPR001320 EMBL-EBI Ionotropic glutamate receptor 7.5E-54
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506694.2 3 447-469,519-541,708-730
T01C3.10 3 447-469,519-541,708-730
GENEFINDER00000022431 2 4-26,189-211
Sequence
Target Sequence 
>C. ELEGANS:192557_S_AT
tatgacgctgtggtgcttgactactgggctggaaaagatgcaaattgtgcattgatgaca
gttggtaaatgggcaagtatgacaggttacggtattggatttccaaagaactcaccgcac
acttctctagtcaatcattacatgctgcagtatcagcagaaaggtgacttggaacgtctt
caaaacttctggctcaccggagcatgtacaccagacagtcacagtcaaacccagtcagca
ccgcttggaatcgagaattttctatcggcatttgtgctgttagccggtggaatcatcgtc
agcgtcattgttcttggatttgagcacatttattgcatgcaccttcggaagcctctacaa
aagattgatccgaatggttggtgtggaattatcagtatggctatgggaaaatctttgaca
ttcacggaagctgttgatcgagttcaagaatggaggtcgaggacacaatcgttggcgagt
acgaattctccgcaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TATGACGCTGTGGTGCTTGACTACT 249 657 1795 Antisense
TGGATTTCCAAAGAACTCACCGCAC 168 551 1890 Antisense
CGCACACTTCTCTAGTCAATCATTA 245 255 1910 Antisense
AAACTTCTGGCTCACCGGAGCATGT 616 127 1977 Antisense
GGAGCATGTACACCAGACAGTCACA 235 521 1993 Antisense
GACAGTCACAGTCAAACCCAGTCAG 208 367 2008 Antisense
CCAGTCAGCACCGCTTGGAATCGAG 428 271 2025 Antisense
GAATTTTCTATCGGCATTTGTGCTG 415 325 2049 Antisense
TCGTCAGCGTCATTGTTCTTGGATT 597 603 2090 Antisense
TTATTGCATGCACCTTCGGAAGCCT 104 679 2124 Antisense
GTTGGCGAGTACGAATTCTCCGCAA 257 435 2265 Antisense
Sequence Source Affymetrix Proprietary Database