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[192551_at] 4-aminobutyrate aminotransferase

Description K04D7.3 /REP_DB=WormBase Gene ID /WP=CE06092 /TR=SW:Q21217 /GB=CAA93517.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=4-aminobutyrate aminotransferase
Cluster 6grp_highest_10_10 > 16      6grp_high1_10_10 > 51      4grp_highest_8_8 > 12      4grp_high_8_8 > 31      6grp_highest_nonorm > 26      6grp_total > 40      4grp_total > 24      6grp_highest_sub > 03_04      6grp_cgc > 83      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1365
1 2 3 4 range
A 4313.6
(-3)
P 		4739.4
(-0.2)
P 		4775.5
(0)
P 		5227.4
(3)
P 		914
B 4533.3
(-3)
P 		5278
(0.9)
P 		5309.6
(1.1)
P 		5678.2
(3)
P 		1145
C 4821.7
(-3)
P 		4937.2
(-1.7)
P 		5374.8
(3)
P 		5007.7
(-1)
P 		553
avr 4556.2
(-3) 		4984.9
(0.4) 		5153.3
(1.8) 		5304.4
(3) 		748

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 4752
1 2 3 4 5 6 range
A 4684.4
(-0.4)
P 		5057.3
(0.1)
P 		7389.8
(3)
P 		5365.8
(0.4)
P 		3966.7
(-1.3)
P 		2638.2
(-3)
P 		4752
B 3866.4
(-1.7)
P 		5914.5
(2.5)
P 		6076.4
(2.8)
P 		6186.6
(3)
P 		4112.7
(-1.2)
P 		3197.7
(-3)
P 		2989
C 4130.7
(-1.4)
P 		5971.2
(1.6)
P 		5979.8
(1.6)
P 		6809.7
(3)
P 		3174.3
(-3)
P 		3601.6
(-2.3)
P 		3635
avr 4227.2
(-1.1) 		5647.7
(1.5) 		6482
(3) 		6120.7
(2.4) 		3751.2
(-1.9) 		3145.8
(-3) 		3336
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1108
1 2 3 4 range
A 1570.6
(3)
P 		1028.8
(-1)
P 		1248.4
(0.6)
P 		765.2
(-3)
P 		805
B 1445.6
(3)
P 		1303.5
(-0.6)
P 		1230.4
(-2.5)
P 		1210
(-3)
P 		236
C 1596.1
(1.4)
P 		1419.5
(0.4)
P 		1873.3
(3)
P 		844.4
(-3)
P 		1029
avr 1537.4
(3) 		1250.6
(0.1) 		1450.7
(2.1) 		939.9
(-3) 		598

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1326
1 2 3 4 5 6 range
A 863.5
(-1.9)
P 		1798.6
(3)
P 		1609.4
(2)
P 		1360.9
(0.7)
P 		1197
(-0.1)
P 		642.3
(-3)
P 		1156
B 1345.3
(-1.8)
P 		1968.7
(3)
P 		1475.5
(-0.8)
P 		1638.6
(0.4)
P 		1670.9
(0.7)
P 		1192.4
(-3)
P 		776
C 1531.1
(0.8)
P 		1822
(3)
P 		1522
(0.7)
P 		1369.4
(-0.4)
P 		1027.2
(-3)
P 		1205.7
(-1.7)
P 		795
avr 1246.6
(-1.4) 		1863.1
(3) 		1535.6
(0.7) 		1456.3
(0.1) 		1298.4
(-1) 		1013.5
(-3) 		850
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192551_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9259
Sequence Type Exemplar sequence
Representative Public ID K04D7.3 NCBI
Target Description K04D7.3 /REP_DB=WormBase Gene ID /WP=CE06092 /TR=SW:Q21217 /GB=CAA93517.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=4-aminobutyrate aminotransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069461(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069461 NCBI Caenorhabditis elegans GABA TransAminase family member (gta-1) (gta-1) mRNA, complete cds. 11/11 None
SNAP00000009542 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10180639:10185321:1 9/11 None
GENEFINDER00000009553 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10181863:10183728:1 11/11 None
K04D7.3 ENSEMBL cdna:known chromosome:CEL140:IV:10180631:10183910:1 gene:K04D7.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10180644-10183734(+) 100.0 100.0
Public Domain and Genome References
Gene Title 4-aminobutyrate aminotransferase
Gene Symbol gta-1
Ensembl K04D7.3
Entrez Gene 177897 Entrez gene
SwissProt Q21217 EMBL-EBI
WormBase CE06092 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1584276_AT similar to 4-aminobutyrate aminotransferase precursor cfa
CANINE_2:CFA.4397.1.A1_S_AT similar to 4-aminobutyrate aminotransferase precursor cfa
DROSOPHILA_2:1626489_S_AT dm
DROSGENOME1:149085_AT dm
CHICKEN:GGA.20060.1.S1_AT 4-aminobutyrate aminotransferase gga
CHICKEN:GGA.2628.1.S1_S_AT 4-aminobutyrate aminotransferase gga
HG-U133_PLUS_2:206527_AT 4-aminobutyrate aminotransferase hs
HG-U133A:206527_AT 4-aminobutyrate aminotransferase hs
HG-FOCUS:206527_AT 4-aminobutyrate aminotransferase hs
HG-U133A_2:206527_AT 4-aminobutyrate aminotransferase hs
HG-U133A:209459_S_AT 4-aminobutyrate aminotransferase hs
HG-U133_PLUS_2:209459_S_AT 4-aminobutyrate aminotransferase hs
HG-U133A_2:209459_S_AT 4-aminobutyrate aminotransferase hs
HG-U95AV2:33446_AT 4-aminobutyrate aminotransferase hs
HU35KSUBA:AA203138_AT 4-aminobutyrate aminotransferase hs
HUGENEFL:U80226_S_AT 4-aminobutyrate aminotransferase hs
HUGENEFL:S75578_S_AT 4-aminobutyrate aminotransferase hs
HUGENEFL:L32961_AT 4-aminobutyrate aminotransferase hs
HG-U133A:209460_AT 4-aminobutyrate aminotransferase hs
HG-U133_PLUS_2:209460_AT 4-aminobutyrate aminotransferase hs
HG-U133A_2:209460_AT 4-aminobutyrate aminotransferase hs
U133_X3P:G9963907_3P_S_AT 4-aminobutyrate aminotransferase hs
U133_X3P:G4501846_3P_AT 4-aminobutyrate aminotransferase hs
HG-U95AV2:36364_AT 4-aminobutyrate aminotransferase hs
HG-U95E:68707_AT 4-aminobutyrate aminotransferase hs
HG-U95AV2:33445_AT 4-aminobutyrate aminotransferase hs
HG-U95E:81048_AT 4-aminobutyrate aminotransferase hs
HU35KSUBC:RC_D11835_AT 4-aminobutyrate aminotransferase hs
MU11KSUBA:AA272187_S_AT 4-aminobutyrate aminotransferase mm
MG-U74CV2:167002_AT 4-aminobutyrate aminotransferase mm
MOE430A:1433855_AT 4-aminobutyrate aminotransferase mm
MOUSE430A_2:1433855_AT 4-aminobutyrate aminotransferase mm
MOUSE430_2:1433855_AT 4-aminobutyrate aminotransferase mm
MG-U74CV2:170369_AT PREDICTED: Mus musculus 4-aminobutyrate aminotransferase (Abat), mRNA mm
MU19KSUBA:TC22817_AT PREDICTED: Mus musculus 4-aminobutyrate aminotransferase (Abat), mRNA mm
RN-U34:D87839_AT 4-aminobutyrate aminotransferase rn
RG-U34A:D87839_AT 4-aminobutyrate aminotransferase rn
RG-U34A:D87839_G_AT 4-aminobutyrate aminotransferase rn
RAE230A:1369799_AT 4-aminobutyrate aminotransferase rn
RAT230_2:1369799_AT 4-aminobutyrate aminotransferase rn
RAE230A:1375321_AT 4-aminobutyrate aminotransferase rn
RAT230_2:1375321_AT 4-aminobutyrate aminotransferase rn
RAE230B:1391365_AT 4-aminobutyrate aminotransferase rn
RAT230_2:1391365_AT 4-aminobutyrate aminotransferase rn
YEAST_2:1774010_AT Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
9448 gamma-aminobutyric acid metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3867 4-aminobutyrate transaminase activity inferred from electronic annotation QuickGO AmiGO
8483 transaminase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93517 Hypothetical protein K04D7.3 [Caenorhabditis elegans] ref|NP_501862.1| GABA TransAminase family member (gta-1) [Caenorhabditis elegans] sp|Q21217|GABT_CAEEL Probable 4-aminobutyrate aminotransferase, mitochondrial precursor ((S)-3-amino-2-methylpropionate transaminase) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA aminotransferase) (GABA-AT) (L-AIBAT) 0.0
blast CAE59915 Hypothetical protein CBG03400 [Caenorhabditis briggsae] 0.0
blast EAA04779 ENSANGP00000021720 [Anopheles gambiae str. PEST] ref|XP_308791.2| ENSANGP00000021720 [Anopheles gambiae str. PEST] 1.0E-129
Protein Domains
Database ID Description E-Value
Pfam IPR005814 EMBL-EBI Aminotransferase class-III 1.1E-118
Pfam IPR005814 EMBL-EBI Aminotransferase class-III 8.8E-107
Pfam IPR005814 EMBL-EBI Aminotransferase class-III 1.3E-118
Sequence
Target Sequence 
>C. ELEGANS:192551_AT
ggaagtccagcattcttccaaggcctccgtgatattacttctaaacatggaattgtattc
attgttgatgaagttcaaactggaggtggagcaactggagatatctgggctcatgatcac
tggaacttgagctctccaccagatatggtcacattctcaaagaaacttttgacaggagga
tacttctacggagaacatctccgagttaaggaggcttaccgtatttacaacacatggatg
ggagatccgaccaagcttcttcttttggaaaaggctgttgaggttattaagagagatgga
ttgattgagcagagcagagaagttggagctgaattccaaaagagacttggagaacttcaa
gcatcgtctggaggaaagttggatcaagccagaggaagaggaacttttgccgccgttgac
ttcccatctggatctttgagagacaaatttgttgacttggccatcagcaacggacttcac
tgtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAAGTCCAGCATTCTTCCAAGGCC 672 531 874 Antisense
TCTTCCAAGGCCTCCGTGATATTAC 61 619 887 Antisense
GGCCTCCGTGATATTACTTCTAAAC 539 543 895 Antisense
GATATCTGGGCTCATGATCACTGGA 184 425 973 Antisense
TCACTGGAACTTGAGCTCTCCACCA 166 627 990 Antisense
CACCAGATATGGTCACATTCTCAAA 57 203 1010 Antisense
GACAGGAGGATACTTCTACGGAGAA 425 365 1044 Antisense
GGAGGCTTACCGTATTTACAACACA 265 515 1083 Antisense
ATCCGACCAAGCTTCTTCTTTTGGA 291 39 1118 Antisense
AAATTTGTTGACTTGGCCATCAGCA 174 117 1318 Antisense
GCCATCAGCAACGGACTTCACTGTG 137 281 1333 Antisense
Sequence Source Affymetrix Proprietary Database