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[192530_at] tyrosine-protein kinase (2 domains)

Description C08H9.8 /REP_DB=WormBase Gene ID /WP=CE02994 /TR=Q17842 /GB=CAA90148.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase (2 domains)
Cluster 6grp_total > 43      4grp_total > 01      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 53
1 2 3 4 range
A 5.5
(-1.9)
A 		2.6
(-3)
A 		3.6
(-2.6)
A 		18.6
(3)
A 		16
B 11.9
(1)
A 		5
(-3)
A 		12
(1)
A 		15.4
(3)
A 		10
C 9.8
(-2.2)
A 		2.5
(-3)
A 		10.6
(-2.1)
A 		55.9
(3)
A 		53
avr 9.1
(-1.7) 		3.4
(-3) 		8.7
(-1.8) 		30
(3) 		27

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 10.8
(-2.8)
A 		15.2
(-2.5)
A 		80
(3)
A 		12.7
(-2.7)
A 		10.1
(-2.9)
A 		8.8
(-3)
A 		71
B 32.5
(2.5)
A 		7.7
(-2.7)
A 		35
(3)
A 		9.4
(-2.3)
A 		13
(-1.6)
A 		6.2
(-3)
A 		29
C 10.2
(-1.3)
A 		29.8
(3)
A 		2.7
(-3)
A 		10.6
(-1.3)
A 		7
(-2)
A 		15.8
(-0.1)
A 		27
avr 17.8
(-1.4) 		17.6
(-1.4) 		39.2
(3) 		10.9
(-2.8) 		10
(-3) 		10.3
(-2.9) 		29
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 9
1 2 3 4 range
A 2
(1)
A 		0.6
(-3)
A 		0.9
(-2.1)
A 		2.7
(3)
A 		2
B 3.8
(3)
A 		1.2
(-3)
A 		2.8
(0.7)
A 		3.3
(1.8)
A 		3
C 3.3
(-1.2)
A 		0.7
(-3)
A 		3.7
(-0.9)
A 		9.4
(3)
A 		9
avr 3
(0.1) 		0.8
(-3) 		2.5
(-0.6) 		5.1
(3) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 17
1 2 3 4 5 6 range
A 2
(-3)
A 		5.4
(-1.7)
A 		17.4
(3)
A 		3.2
(-2.5)
A 		3.1
(-2.6)
A 		2.1
(-3)
A 		15
B 11.3
(3)
A 		2.6
(-2.8)
A 		8.5
(1.1)
A 		2.5
(-2.9)
A 		5.3
(-1)
A 		2.3
(-3)
A 		9
C 3.8
(-0.8)
A 		9.1
(3)
A 		0.7
(-3)
A 		2.1
(-2)
A 		2.3
(-1.9)
A 		5.3
(0.3)
A 		8
avr 5.7
(-0) 		5.7
(-0) 		8.9
(3) 		2.6
(-3) 		3.6
(-2) 		3.2
(-2.4) 		6
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192530_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3190
Sequence Type Exemplar sequence
Representative Public ID C08H9.8 NCBI
Target Description C08H9.8 /REP_DB=WormBase Gene ID /WP=CE02994 /TR=Q17842 /GB=CAA90148.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063723(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063723 NCBI Caenorhabditis elegans C08H9.8 (C08H9.8) mRNA, complete cds. 11/11 None
C08H9.8 ENSEMBL cdna:known chromosome:CEL140:II:9851480:9853114:-1 gene:C08H9.8 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000001366 3/11 Cross Hyb Matching Probes None
GENEFINDER00000001390 3/11 Cross Hyb Matching Probes None
SNAP00000044683 2/11 Cross Hyb Matching Probes None
GENEFINDER00000044689 5/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:9851476-9853302(-) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase (2 domains)
Ensembl C08H9.8
Entrez Gene 182433 Entrez gene
SwissProt Q17842 EMBL-EBI
WormBase CE36468 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91155 Hypothetical protein C08H9.8 [Caenorhabditis elegans] emb|CAA90148.2| Hypothetical protein C08H9.8 [Caenorhabditis elegans] ref|NP_496124.2| C08H9.8 [Caenorhabditis elegans] 0.0
blast CAB01652 Hypothetical protein M176.7 [Caenorhabditis elegans] ref|NP_496017.1| protein KINase family member (kin-16) [Caenorhabditis elegans] sp|P34892|KIN16_CAEEL Receptor-like tyrosine-protein kinase kin-16 precursor gb|AAA28152.1| protein-tyrosine kinase 1.0E-61
blast CAB05559 Hypothetical protein M01B2.1 [Caenorhabditis elegans] ref|NP_506771.2| protein KINase family member (kin-30) [Caenorhabditis elegans] 4.0E-59
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.7E-40
Sequence
Target Sequence 
>C. ELEGANS:192530_AT
gaacgatttcaagccaaacagcctatttggtctaatgaagataacagtggatacctcatt
cctaagagtaaacccattgaaaactcattgtatacatctggcctactctcgtttgcatat
caaatagcaaatggaatgaaacatttggcatctgtcctttgtgtccaccgagatctggct
ctgcgtaatatattggtaaaaagaaataaaataattcgaatcagtgattttgaagttctg
agcggctatgatgttccccttcccttcttctggttagcgccggaatgttttgaagaatac
aaattttcagaaaaaactgatgtatgggcatttggaatttgtttatatgaattgttttct
ctgggcgaaacactatataaagatattcccgcgagcggaaataccgttgatgcaatcata
gaattcctgaaagttggtaatcggctcccgcaaccagagcattgttctttccgaatttac
gaattcatgaaactatgctggagtactgacccgattaaacgtccaacg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAACGATTTCAAGCCAAACAGCCTA 525 347 667 Antisense
CATTGTATACATCTGGCCTACTCTC 605 217 752 Antisense
GCCTACTCTCGTTTGCATATCAAAT 183 283 767 Antisense
CCGAGATCTGGCTCTGCGTAATATA 692 263 834 Antisense
TTCTGAGCGGCTATGATGTTCCCCT 74 693 902 Antisense
CTTCTTCTGGTTAGCGCCGGAATGT 197 221 930 Antisense
TTCCCGCGAGCGGAAATACCGTTGA 142 699 1052 Antisense
TGAAAGTTGGTAATCGGCTCCCGCA 420 571 1094 Antisense
GCAACCAGAGCATTGTTCTTTCCGA 120 321 1116 Antisense
AACTATGCTGGAGTACTGACCCGAT 517 139 1157 Antisense
TACTGACCCGATTAAACGTCCAACG 573 637 1170 Antisense
Sequence Source Affymetrix Proprietary Database