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[192517_at] Src homology domain 3

Description Y37A1B.14 /REP_DB=WormBase Gene ID /WP=CE19084 /TR=Q9XXG4 /GB=CAA19485.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Src homology domain 3 (2 domains)
Cluster 6grp_total > 31      4grp_total > 62      6grp_cgc > 81      6grp_cgc_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 82
1 2 3 4 range
A 76.6
(3)
A 		33.9
(-2.7)
A 		31.9
(-3)
A 		33.5
(-2.8)
A 		45
B 83.6
(3)
A 		66.8
(0.6)
A 		69.8
(1.1)
A 		40.9
(-3)
A 		43
C 102.8
(3)
A 		51
(-0.8)
A 		83.6
(1.6)
A 		21
(-3)
A 		82
avr 87.7
(3) 		50.6
(-1) 		61.8
(0.2) 		31.8
(-3) 		56

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 96
1 2 3 4 5 6 range
A 11.6
(-2.6)
A 		88.6
(3)
A 		51.3
(0.3)
A 		52
(0.4)
A 		21
(-1.9)
A 		5.4
(-3)
A 		83
B 25.3
(-0)
A 		40.8
(3)
A 		30.8
(1.1)
A 		39
(2.7)
A 		9.9
(-3)
A 		11.1
(-2.8)
A 		31
C 67.7
(1)
A 		27.5
(-1.6)
A 		100.2
(3)
A 		7.9
(-2.8)
A 		35.9
(-1)
A 		4.6
(-3)
A 		96
avr 34.9
(0.1) 		52.3
(2.1) 		60.8
(3) 		33
(-0.1) 		22.3
(-1.3) 		7
(-3) 		54
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 31
1 2 3 4 range
A 27.9
(3)
A 		7.4
(-2.3)
A 		8.3
(-2.1)
A 		4.9
(-3)
A 		23
B 26.7
(3)
A 		16.5
(-0.4)
A 		16.2
(-0.5)
A 		8.7
(-3)
A 		18
C 34
(3)
A 		14.7
(-0.8)
A 		29.2
(2.1)
A 		3.5
(-3)
A 		31
avr 29.5
(3) 		12.9
(-1.2) 		17.9
(0.1) 		5.7
(-3) 		24

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 30
1 2 3 4 5 6 range
A 2.1
(-2.8)
A 		31.5
(3)
A 		11.2
(-1)
A 		13.2
(-0.6)
A 		6.3
(-2)
A 		1.3
(-3)
A 		30
B 8.8
(0)
A 		13.6
(3)
A 		7.5
(-0.8)
A 		10.3
(0.9)
A 		4
(-3)
A 		4.1
(-2.9)
A 		10
C 25.1
(2.9)
A 		8.4
(-1.3)
A 		25.5
(3)
A 		1.6
(-3)
A 		11.6
(-0.5)
A 		1.5
(-3)
A 		24
avr 12
(0.8) 		17.8
(3) 		14.7
(1.8) 		8.4
(-0.6) 		7.3
(-1.1) 		2.3
(-3) 		16
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192517_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8900
Sequence Type Exemplar sequence
Representative Public ID Y37A1B.14 NCBI
Target Description Y37A1B.14 /REP_DB=WormBase Gene ID /WP=CE19084 /TR=Q9XXG4 /GB=CAA19485.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Src homology domain 3 (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070280(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070280 NCBI Caenorhabditis elegans GEX Interacting protein family member (gei-18) (gei-18) mRNA, complete cds. 11/11 None
SNAP00000004214 ENSEMBL cdna:SNAP chromosome:CEL140:IV:13973147:13979808:-1 11/11 None
GENEFINDER00000004237 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:13973246:13979808:-1 11/11 None
Y37A1B.15 ENSEMBL cdna:known chromosome:CEL140:IV:13964340:13982492:-1 gene:Y37A1B.15 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:13976924-13982498(-) 100.0 100.0
Public Domain and Genome References
Gene Title Src homology domain 3
Gene Symbol gei-18
Ensembl Y37A1B.15
Entrez Gene 178357 Entrez gene
SwissProt Q9TVW6 EMBL-EBI
WormBase CE36232 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB05124 Hypothetical protein Y37A1B.15 [Caenorhabditis elegans] emb|CAA19497.3| Hypothetical protein Y37A1B.15 [Caenorhabditis elegans] ref|NP_502681.2| GEX Interacting protein family member (gei-18) [Caenorhabditis elegans] 0.0
blast T26607 hypothetical protein Y37A1B.14 - Caenorhabditis elegans 0.0
blast CAE74661 Hypothetical protein CBG22462 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001452 EMBL-EBI SH3 5.7E-12
Pfam IPR001452 EMBL-EBI SH3 1.7E-11
Pfam IPR001452 EMBL-EBI SH3 1.9E-9
Pfam IPR000219 EMBL-EBI DH domain 1.5E-11
Pfam IPR001452 EMBL-EBI SH3 5.7E-12
Pfam IPR001452 EMBL-EBI SH3 1.7E-11
Pfam IPR000219 EMBL-EBI DH domain 1.5E-11
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502681.2 2 78-97,1752-1774
Y37A1B.15 2 78-97,1752-1774
Sequence
Target Sequence 
>C. ELEGANS:192517_AT
ggagggaccagcgattttacgtttggtagctccaacaatcgttcctccttcatctcaaat
gctgaatcctcatccgattggagaccacccgctggaagaacaaacaccgattgggcaacc
tttgaagcagttccaccggcagcgcctgcatcaaaacctgcccaaaattgggcaaccttc
ggcgaagaatggattgctccagttcagctagcaaagacttcagctccagcccgaccacca
cctcctaagcaaagttctattcaatcacctatcaatgatattggcaacgtggctgacatg
tttggaatgacagatactccaaaaccaagtaaccctgcgatccagtctgctggcagtgac
ttcgaaattggactgatttccgccaccgaaggagcatcaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAGGGACCAGCGATTTTACGTTTG 95 515 1708 Antisense
TTCCTCCTTCATCTCAAATGCTGAA 123 701 1749 Antisense
GAATCCTCATCCGATTGGAGACCAC 112 331 1771 Antisense
GAGACCACCCGCTGGAAGAACAAAC 456 379 1788 Antisense
GGGCAACCTTTGAAGCAGTTCCACC 575 493 1820 Antisense
GGCAGCGCCTGCATCAAAACCTGCC 43 537 1845 Antisense
ATGGATTGCTCCAGTTCAGCTAGCA 311 51 1896 Antisense
CACCACCTCCTAAGCAAAGTTCTAT 91 203 1943 Antisense
TCCAAAACCAAGTAACCCTGCGATC 466 585 2025 Antisense
GCGATCCAGTCTGCTGGCAGTGACT 441 285 2044 Antisense
TTTCCGCCACCGAAGGAGCATCAAA 441 669 2084 Antisense
Sequence Source Affymetrix Proprietary Database