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[192510_s_at] Src homology domain 3

Description Y37A1B.15 /REP_DB=WormBase Gene ID /WP=CE24205 /GEN=gei-18 /TR=Q9TVW6 /GB=CAA19497.2 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Src homology domain 3
Cluster 6grp_highest_10_10 > 51      6grp_high1_10_10 > 25      4grp_high_8_8 > 42      6grp_highest_nonorm > 70      6grp_total > 16      4grp_total > 53      6grp_highest_sub > De      6grp_cgc > 23      6grp_high1_sub > 01_02      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 254
1 2 3 4 range
A 409.5
(3)
P 		319.5
(0.9)
P 		245.1
(-0.9)
P 		155.7
(-3)
A 		254
B 352.5
(3)
P 		313.2
(-0)
P 		274
(-3)
P 		289.1
(-1.8)
P 		79
C 349.9
(3)
P 		290
(0.7)
P 		291.2
(0.7)
P 		195.5
(-3)
P 		154
avr 370.6
(3) 		307.6
(0.6) 		270.1
(-0.8) 		213.4
(-3) 		157

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 227
1 2 3 4 5 6 range
A 344.4
(2.8)
P 		349.7
(3)
P 		198.9
(-3)
P 		198.2
(-3)
P 		230.5
(-1.7)
P 		252
(-0.9)
P 		152
B 401.3
(3)
P 		359.1
(1.9)
P 		259.9
(-0.8)
P 		252.7
(-1)
P 		178.2
(-3)
P 		202.4
(-2.3)
P 		223
C 337.8
(3)
P 		332.2
(2.8)
P 		231.3
(-0.9)
P 		180
(-2.8)
P 		230.2
(-1)
P 		174.6
(-3)
P 		163
avr 361.2
(3) 		347
(2.4) 		230
(-2.2) 		210.3
(-3) 		213
(-2.9) 		209.7
(-3) 		152
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 126
1 2 3 4 range
A 149.1
(3)
P 		69.4
(-0.8)
P 		64.1
(-1)
P 		22.8
(-3)
A 		126
B 112.4
(3)
P 		77.4
(-1.1)
P 		63.5
(-2.8)
P 		61.6
(-3)
P 		51
C 115.8
(3)
P 		83.4
(0.7)
P 		101.5
(2)
P 		33
(-3)
P 		83
avr 125.8
(3) 		76.7
(-0.4) 		76.4
(-0.4) 		39.1
(-3) 		87

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 103
1 2 3 4 5 6 range
A 63.5
(-1.5)
P 		124.4
(3)
P 		43.3
(-3)
P 		50.3
(-2.5)
P 		69.6
(-1.1)
P 		61.4
(-1.7)
P 		81
B 139.6
(3)
P 		119.5
(1.4)
P 		63.1
(-3)
P 		66.9
(-2.7)
P 		72.4
(-2.3)
P 		75.5
(-2)
P 		77
C 125.2
(3)
P 		101.4
(1.4)
P 		58.9
(-1.5)
P 		36.2
(-3)
P 		74.5
(-0.4)
P 		58.5
(-1.5)
P 		89
avr 109.4
(2.5) 		115.1
(3) 		55.1
(-2.6) 		51.1
(-3) 		72.2
(-1) 		65.1
(-1.7) 		64
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192510_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8706
Sequence Type Exemplar sequence
Representative Public ID Y37A1B.15 NCBI
Target Description Y37A1B.15 /REP_DB=WormBase Gene ID /WP=CE24205 /GEN=gei-18 /TR=Q9TVW6 /GB=CAA19497.2 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Src homology domain 3
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070280(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070280 NCBI Caenorhabditis elegans GEX Interacting protein family member (gei-18) (gei-18) mRNA, complete cds. 11/11 None
Y37A1B.15 ENSEMBL cdna:known chromosome:CEL140:IV:13964340:13982492:-1 gene:Y37A1B.15 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000005808 1/11 Cross Hyb Matching Probes None
GENEFINDER00000005812 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:13964713-13976708(-) 100.0 100.0
Public Domain and Genome References
Gene Title Src homology domain 3
Gene Symbol gei-18
Ensembl Y37A1B.15
Entrez Gene 178357 Entrez gene
SwissProt Q9TVW6 EMBL-EBI
WormBase CE36232 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB05124 Hypothetical protein Y37A1B.15 [Caenorhabditis elegans] emb|CAA19497.3| Hypothetical protein Y37A1B.15 [Caenorhabditis elegans] ref|NP_502681.2| GEX Interacting protein family member (gei-18) [Caenorhabditis elegans] 0.0
blast T26607 hypothetical protein Y37A1B.14 - Caenorhabditis elegans 0.0
blast CAE74661 Hypothetical protein CBG22462 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001452 EMBL-EBI SH3 5.7E-12
Pfam IPR001452 EMBL-EBI SH3 1.7E-11
Pfam IPR001452 EMBL-EBI SH3 1.9E-9
Pfam IPR000219 EMBL-EBI DH domain 1.5E-11
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502681.2 2 78-97,1752-1774
Y37A1B.15 2 78-97,1752-1774
Sequence
Target Sequence 
>C. ELEGANS:192510_S_AT
cgcagctcagcctacgaatgtgtggccgacaacgtctatgatgtctagaagtgactcgcc
gcagccgctaattccatctcgccctgagccggctgtcaaaaatgtgtacccgagcttgaa
tgatggctctgcaagggctcccacatttgctacaacattcccgtcacaagccaaccaatc
tttgccaatgtactcagcagtgccaaatgatacgatgagtatgaactatgcgatgccacc
aatgtatgatacaactccgcagtctccacgagttcaactgcagcaacaacaccagccagc
cgcgtatgacactcctccaacaattgcaccaatttatgatcaacttccaaacgagtctcc
ggcgtcgacagcgattcgtccagtgctgtgccaagtaaaagtcgactacgacttccttcc
acaaggatccaatcaagtcgaagtgaaagaaggagaagtaattggggtcttgcaacgaac
agacgatgatggaaacccagaatggctactcatcaaaagagacagcggaaaagtcggata
tgtaccggcggcatattattatgtaatcgcctcacattttcctt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGCAGCTCAGCCTACGAATGTGTGG 199 255 2409 Antisense
GAATGTGTGGCCGACAACGTCTATG 647 331 2424 Antisense
ATGTCTAGAAGTGACTCGCCGCAGC 91 49 2449 Antisense
AAATGTGTACCCGAGCTTGAATGAT 270 121 2508 Antisense
TGAATGATGGCTCTGCAAGGGCTCC 284 575 2525 Antisense
CGTCACAAGCCAACCAATCTTTGCC 398 247 2570 Antisense
GAACTATGCGATGCCACCAATGTAT 502 349 2631 Antisense
TGATCAACTTCCAAACGAGTCTCCG 237 559 2745 Antisense
GTCGACAGCGATTCGTCCAGTGCTG 677 473 2772 Antisense
AAGTCGGATATGTACCGGCGGCATA 587 157 2939 Antisense
TATGTAATCGCCTCACATTTTCCTT 185 657 2968 Antisense
Sequence Source Affymetrix Proprietary Database