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[192507_at] mecanosensory gene mec-8

Description F46A9.6 /REP_DB=WormBase Gene ID /WP=CE08260 /GEN=mec-8 /TR=Q19018 /GB=CAB03111.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=mecanosensory gene mec-8
Cluster 6grp_highest_10_10 > 50      6grp_high1_10_10 > 15      4grp_highest_8_8 > 57      4grp_high_8_8 > 41      6grp_highest_nonorm > 30      6grp_total > 05      4grp_total > 45      6grp_highest_sub > De      6grp_cgc > 13      6grp_high1_sub > De      6grp_cgc_sub > De      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 778
1 2 3 4 range
A 1303.1
(3)
P 		885.1
(-0.6)
P 		705.7
(-2.1)
P 		604.6
(-3)
P 		699
B 1382.1
(3)
P 		921.8
(-0.9)
P 		763.4
(-2.3)
P 		677.9
(-3)
P 		704
C 1273.1
(3)
P 		1016.1
(0.7)
P 		747.6
(-1.7)
P 		608.6
(-3)
P 		665
avr 1319.4
(3) 		941
(-0.3) 		738.9
(-2.1) 		630.4
(-3) 		689

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 872
1 2 3 4 5 6 range
A 1232.9
(3)
P 		1173.6
(2.5)
P 		542.5
(-3)
P 		849
(-0.3)
P 		756.5
(-1.1)
P 		698.5
(-1.6)
P 		690
B 1012.7
(3)
P 		981.9
(2.6)
P 		596
(-2.7)
P 		798.5
(0.1)
P 		699.8
(-1.3)
P 		571.5
(-3)
P 		441
C 1380.3
(3)
P 		896.5
(-0.3)
P 		861.4
(-0.6)
P 		722
(-1.5)
P 		867.3
(-0.5)
P 		508.1
(-3)
P 		872
avr 1208.6
(3) 		1017.3
(1.1) 		666.6
(-2.3) 		789.8
(-1.1) 		774.5
(-1.2) 		592.7
(-3) 		616
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 386
1 2 3 4 range
A 474.5
(3)
P 		192.1
(-1.4)
P 		184.5
(-1.5)
P 		88.5
(-3)
P 		386
B 440.7
(3)
P 		227.7
(-1.3)
P 		176.9
(-2.3)
P 		144.5
(-3)
P 		296
C 421.4
(3)
P 		292.1
(0.6)
P 		260.5
(-0)
P 		102.6
(-3)
P 		319
avr 445.5
(3) 		237.3
(-0.7) 		207.3
(-1.3) 		111.9
(-3) 		334

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 394
1 2 3 4 5 6 range
A 227.3
(-0.8)
P 		417.4
(3)
P 		118.1
(-3)
P 		215.3
(-1.1)
P 		228.3
(-0.8)
P 		170.1
(-2)
P 		299
B 352.4
(3)
P 		326.8
(2.3)
P 		144.7
(-3)
P 		211.5
(-1.1)
P 		284.3
(1)
P 		213.1
(-1)
P 		208
C 511.6
(3)
P 		273.6
(-0.9)
P 		219.2
(-1.8)
P 		145.2
(-3)
P 		280.6
(-0.8)
P 		170.1
(-2.6)
P 		366
avr 363.8
(3) 		339.3
(2.3) 		160.7
(-3) 		190.7
(-2.1) 		264.4
(0.1) 		184.4
(-2.3) 		203
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192507_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1720
Sequence Type Exemplar sequence
Representative Public ID F46A9.6 NCBI
Target Description F46A9.6 /REP_DB=WormBase Gene ID /WP=CE08260 /GEN=mec-8 /TR=Q19018 /GB=CAB03111.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=mecanosensory gene mec-8
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060107(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060107 NCBI Caenorhabditis elegans MEChanosensory abnormality family member (mec-8) (mec-8) mRNA, complete cds. 11/11 A 
F46A9.6.1 ENSEMBL cdna:known chromosome:CEL140:I:9449133:9452351:-1 gene:F46A9.6 11/11 A 
F46A9.6.2 ENSEMBL cdna:known chromosome:CEL140:I:9450096:9458855:-1 gene:F46A9.6 11/11 A 
F46A9.6.3 ENSEMBL cdna:known chromosome:CEL140:I:9450096:9452353:-1 gene:F46A9.6 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000008774 8/11 Cross Hyb Matching Probes None
GENEFINDER00000008781 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9450026-9452250(-) 100.0 100.0
Public Domain and Genome References
Gene Title mecanosensory gene mec-8
Gene Symbol mec-8
Ensembl F46A9.6
Entrez Gene 172771 Entrez gene
SwissProt Q19018 EMBL-EBI
WormBase CE08260 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.26159.1.S1_AT similar to RNA binding protein with multiple splicing 2 cfa
CANINE_2:CFAAFFX.26161.1.S1_AT similar to RNA binding protein with multiple splicing 2 cfa
CANINE_2:CFAAFFX.26161.1.S1_X_AT similar to RNA binding protein with multiple splicing 2 cfa
CHICKEN:GGA.2695.1.S1_AT RNA binding protein with multiple splicing 2 gga
HU35KSUBC:RC_AA303081_AT RNA binding protein with multiple splicing 2 hs
U133_X3P:HS.78293.0.A1_3P_AT RNA binding protein with multiple splicing 2 hs
HG-U133_PLUS_2:228802_AT RNA binding protein with multiple splicing 2 hs
HG-U133B:228802_AT RNA binding protein with multiple splicing 2 hs
HG-U95C:64751_AT RNA binding protein with multiple splicing 2 hs
HG-U95E:83594_AT RNA binding protein with multiple splicing 2 hs
MG-U74BV2:109167_AT RNA binding protein with multiple splicing 2 mm
MOE430A:1424008_A_AT RNA binding protein with multiple splicing 2 mm
MOUSE430A_2:1424008_A_AT RNA binding protein with multiple splicing 2 mm
MOUSE430_2:1424008_A_AT RNA binding protein with multiple splicing 2 mm
MU19KSUBB:TC34072_AT RNA binding protein with multiple splicing 2 (Rbpms2), mRNA mm
Protein Similarities
Method ID Description E-Value
blast CAB03111 Hypothetical protein F46A9.6 [Caenorhabditis elegans] emb|CAB02754.1| Hypothetical protein F46A9.6 [Caenorhabditis elegans] emb|CAA64867.1| mec-8 [Caenorhabditis elegans] ref|NP_492508.1| MEChanosensory abnormality family member (mec-8) [Caenorhabditis elegans] 1.0E-127
blast CAA64866 mec-8 [Caenorhabditis elegans] 1.0E-127
blast CAE60190 Hypothetical protein CBG03748 [Caenorhabditis briggsae] 1.0E-114
Protein Domains
Database ID Description E-Value
Pfam IPR000504 EMBL-EBI RNA-binding region RNP-1 (RNA recognition motif) 2.4E-9
Pfam IPR000504 EMBL-EBI RNA-binding region RNP-1 (RNA recognition motif) 1.0E-8
Sequence
Target Sequence 
>C. ELEGANS:192507_AT
gtagctcgacctaaacaatctccaccaccaccacaacatgcggcactatcagccgctgca
gccggagtcccgcagtttttggcaccaatgcaacacgatcttctactagatcctcaatca
gcagctcttttcaatgagcaacaactattggctctttcacttccacatttacatgctgca
caggcacttcaagcagcctatatgccagcttctgctctacaacaatacagtcagaatcaa
ttgtttgcagctgctcaaatgcacccagcagccgctgcagcagccagcctccaacattct
caacaagcatctcaagcttccacctctgcgtgctccactcttttcgtcgccaatctatcg
gctgaagtgaatgaagatactcttcggggtgtattcaaagcattctctggtttcacacgt
ctacgactgcacaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTAGCTCGACCTAAACAATCTCCAC 36 457 361 Antisense
CATGCGGCACTATCAGCCGCTGCAG 62 211 397 Antisense
GCACCAATGCAACACGATCTTCTAC 299 315 442 Antisense
GATCCTCAATCAGCAGCTCTTTTCA 186 417 469 Antisense
AACAACTATTGGCTCTTTCACTTCC 257 135 500 Antisense
TTCACTTCCACATTTACATGCTGCA 298 687 516 Antisense
TACATGCTGCACAGGCACTTCAAGC 71 645 530 Antisense
AAGCAGCCTATATGCCAGCTTCTGC 620 151 551 Antisense
CTCTTTTCGTCGCCAATCTATCGGC 414 229 698 Antisense
TCAAAGCATTCTCTGGTTTCACACG 502 629 755 Antisense
GTTTCACACGTCTACGACTGCACAA 535 449 770 Antisense
Sequence Source Affymetrix Proprietary Database