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[192458_at] integral membrane protein E16 like

Description F27C8.1 /REP_DB=WormBase Gene ID /WP=CE03266 /TR=Q19834 /GB=CAA92459.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=integral membrane protein E16 like
Cluster 6grp_highest_10_10 > 17      6grp_high1_10_10 > 61      4grp_high_8_8 > 50      6grp_highest_nonorm > 53      6grp_total > 61      4grp_total > 61      6grp_highest_sub > 04      6grp_cgc > 84      6grp_high1_sub > 04      6grp_cgc_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 355
1 2 3 4 range
A 490
(3)
P 		281.2
(-0.5)
P 		391.1
(1.3)
P 		134.9
(-3)
A 		355
B 478
(3)
P 		414
(1.7)
P 		310.8
(-0.3)
P 		175.8
(-3)
A 		302
C 455.1
(2.8)
P 		466.6
(3)
P 		442.9
(2.5)
P 		184.1
(-3)
P 		283
avr 474.4
(3) 		387.3
(1.3) 		381.6
(1.2) 		164.9
(-3) 		310

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1318
1 2 3 4 5 6 range
A 713.8
(-0.3)
P 		740.4
(-0.2)
P 		1159.5
(2.4)
P 		1265.4
(3)
P 		957.7
(1.2)
P 		267.2
(-3)
P 		998
B 725.9
(-1.1)
P 		785.2
(-0.8)
P 		994.5
(0.2)
P 		1585.5
(3)
P 		801.8
(-0.7)
P 		315.4
(-3)
P 		1270
C 562.1
(-1.8)
P 		894.4
(0.1)
P 		1223.9
(1.9)
P 		1411.9
(3)
P 		715.2
(-0.9)
P 		347.8
(-3)
P 		1064
avr 667.3
(-1.1) 		806.7
(-0.3) 		1126
(1.4) 		1420.9
(3) 		824.9
(-0.2) 		310.1
(-3) 		1111
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 159
1 2 3 4 range
A 178.4
(3)
P 		61
(-1.4)
P 		102.2
(0.1)
P 		19.7
(-3)
A 		159
B 152.4
(3)
P 		102.2
(0.4)
P 		72
(-1.2)
P 		37.5
(-3)
A 		115
C 150.6
(2.8)
P 		134.1
(2)
P 		154.4
(3)
P 		31
(-3)
P 		123
avr 160.5
(3) 		99.1
(0.2) 		109.5
(0.7) 		29.4
(-3) 		131

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 355
1 2 3 4 5 6 range
A 131.6
(-1.4)
P 		263.3
(1.6)
P 		252.5
(1.4)
P 		320.9
(3)
P 		289
(2.3)
P 		65
(-3)
P 		256
B 252.6
(-0.3)
P 		261.3
(-0.1)
P 		241.5
(-0.5)
P 		419.9
(3)
P 		325.8
(1.1)
P 		117.6
(-3)
P 		302
C 208.3
(-0.2)
P 		272.9
(1.8)
P 		311.5
(3)
P 		283.9
(2.2)
P 		231.4
(0.5)
P 		116.4
(-3)
P 		195
avr 197.5
(-0.6) 		265.8
(1.1) 		268.5
(1.2) 		341.6
(3) 		282.1
(1.5) 		99.7
(-3) 		242
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192458_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8558
Sequence Type Exemplar sequence
Representative Public ID F27C8.1 NCBI
Target Description F27C8.1 /REP_DB=WormBase Gene ID /WP=CE03266 /TR=Q19834 /GB=CAA92459.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=integral membrane protein E16 like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069306(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069306 NCBI Caenorhabditis elegans Amino Acid Transporter family member (aat-1) (aat-1) mRNA, complete cds. 11/11 None
SNAP00000022612 ENSEMBL cdna:SNAP chromosome:CEL140:IV:9599411:9601671:-1 11/11 None
GENEFINDER00000022615 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:9599411:9601671:-1 11/11 None
F27C8.1 ENSEMBL cdna:known chromosome:CEL140:IV:9598963:9601672:-1 gene:F27C8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9599416-9601677(-) 100.0 100.0
Public Domain and Genome References
Gene Title integral membrane protein E16 like
Gene Symbol aat-1
Ensembl F27C8.1
Entrez Gene 177793 Entrez gene
SwissProt Q19834 EMBL-EBI
WormBase CE03266 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.30456.1.S1_AT similar to Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (hLAT1) cfa
DROSOPHILA_2:1634383_A_AT dm
DROSGENOME1:154874_AT dm
CHICKEN:GGA.13519.1.S1_S_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 gga
CHICKEN:GGA.15743.1.S1_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 gga
CHICKEN:GGAAFFX.12896.1.S1_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 gga
HG-U133_PLUS_2:201195_S_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 hs
HG-U133A:201195_S_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 hs
HG-FOCUS:201195_S_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 hs
HG-U133A_2:201195_S_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 hs
HUGENEFL:M80244_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 hs
U133_X3P:G5926731_3P_A_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 hs
U133_X3P:HS2.325520.2.A1_3P_S_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 hs
HG-U95AV2:32186_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 hs
MG-U74AV2:104221_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 mm
MOE430A:1418326_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 mm
MOUSE430A_2:1418326_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 mm
MOUSE430_2:1418326_AT solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 mm
MU19KSUBA:TC23788_AT Solute carrier family 7 (cationic amino acid transporter, y+ system), member 5, mRNA (cDNA clone MGC:13766 IMAGE:4188854) mm
MU19KSUBA:TC23788_G_AT Solute carrier family 7 (cationic amino acid transporter, y+ system), member 5, mRNA (cDNA clone MGC:13766 IMAGE:4188854) mm
RG-U34A:AB015432_S_AT tumor-associated protein 1 rn
RAE230A:1387280_A_AT tumor-associated protein 1 rn
RAT230_2:1387280_A_AT tumor-associated protein 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92459 Hypothetical protein F27C8.1 [Caenorhabditis elegans] ref|NP_501707.1| Amino Acid Transporter family member (aat-1) [Caenorhabditis elegans] 0.0
blast CAE72788 Hypothetical protein CBG20050 [Caenorhabditis briggsae] 0.0
blast CAE58861 Hypothetical protein CBG02089 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR004841 EMBL-EBI Amino acid permease-associated region 6.2E-30
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501707.1 12 32-54,64-86,115-137,152-174,181-203,223-245,257-279,306-328,356-373,383-402,415-437,442-461
F27C8.1 12 32-54,64-86,115-137,152-174,181-203,223-245,257-279,306-328,356-373,383-402,415-437,442-461
SNAP00000022612 12 32-54,64-86,115-137,152-174,181-203,223-245,257-279,306-328,356-373,383-402,415-437,442-461
GENEFINDER00000022615 12 32-54,64-86,115-137,152-174,181-203,223-245,257-279,306-328,356-373,383-402,415-437,442-461
Sequence
Target Sequence 
>C. ELEGANS:192458_AT
ggctgtagcggtacttttcgccaataaactctatggaaaattcgcatttattatgccact
ctgtgttgcatgttccacaattggatcagctaatggagttattttcacttcagcgagact
tttttattccggtgctcgtgaaggacaaatgccagctgtattgacaatgattaataaaaa
aacgaaaacaccgattcccgctgttattcttaccggagctctttctattgcttacttgtt
ggcatcaaaggatgtgtatcaattgattaattatattcaaatcagttactggcttgcaat
cggaacagccattgccgcactcttctggcttcgtagaaccatgccagatgcatcaagacc
aattaaagttccactcatttggccagctattttccttgctggatgtatcgctcttgttct
tattccaatggtagctgctccaagagatacgggaattggtctacttatcatgctttccgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGCTGTAGCGGTACTTTTCGCCAAT 710 539 888 Antisense
ATGCCACTCTGTGTTGCATGTTCCA 432 41 940 Antisense
GTTATTTTCACTTCAGCGAGACTTT 481 447 985 Antisense
GAGACTTTTTTATTCCGGTGCTCGT 127 393 1002 Antisense
GATTCCCGCTGTTATTCTTACCGGA 687 431 1080 Antisense
TACCGGAGCTCTTTCTATTGCTTAC 146 651 1098 Antisense
GCAATCGGAACAGCCATTGCCGCAC 582 321 1183 Antisense
TAAAGTTCCACTCATTTGGCCAGCT 35 641 1251 Antisense
TTTCCTTGCTGGATGTATCGCTCTT 616 669 1278 Antisense
TATCGCTCTTGTTCTTATTCCAATG 356 659 1293 Antisense
TTGGTCTACTTATCATGCTTTCCGC 516 707 1343 Antisense
Sequence Source Affymetrix Proprietary Database