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[192446_s_at] ribose-phosphate pyrophosphokinase

Description W04G3.5 /REP_DB=WormBase Gene ID /WP=CE03789 /TR=Q23166 /GB=CAA92027.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=ribose-phosphate pyrophosphokinase
Cluster 6grp_highest_10_10 > 46      6grp_high1_10_10 > 54      4grp_highest_8_8 > 26      4grp_high_8_8 > 59      6grp_highest_nonorm > 76      6grp_total > 54      4grp_total > 60      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 750
1 2 3 4 range
A 1420.8
(1.8)
P 		1300.6
(-1)
P 		1472.4
(3)
P 		1211.5
(-3)
P 		261
B 1521.5
(1.5)
P 		1365.1
(0.1)
P 		1690
(3)
P 		1014.4
(-3)
P 		676
C 1339.6
(2.3)
P 		1307
(1.9)
P 		1391.1
(3)
P 		939.9
(-3)
P 		451
avr 1427.3
(1.8) 		1324.2
(0.5) 		1517.8
(3) 		1055.3
(-3) 		463

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 510
1 2 3 4 5 6 range
A 1248.7
(0.4)
P 		1399.1
(3)
P 		1237.9
(0.2)
P 		1047.5
(-3)
P 		1114.2
(-1.9)
P 		1202.4
(-0.4)
P 		352
B 1218
(-1.1)
P 		1186.5
(-1.6)
P 		1495.2
(3)
P 		1191.7
(-1.5)
P 		1090.3
(-3)
P 		1239.9
(-0.8)
P 		405
C 1089.8
(-1.4)
P 		1027.2
(-2.3)
P 		1369.4
(3)
P 		984.9
(-3)
P 		1321.9
(2.3)
P 		1269
(1.4)
P 		385
avr 1185.5
(-0.7) 		1204.3
(-0.3) 		1367.5
(3) 		1074.7
(-3) 		1175.5
(-0.9) 		1237.1
(0.3) 		293
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 359
1 2 3 4 range
A 517.3
(3)
P 		282.3
(-1.1)
P 		384.9
(0.7)
P 		177.3
(-3)
P 		340
B 485.2
(3)
P 		337.1
(-0.3)
P 		391.6
(0.9)
P 		216.2
(-3)
P 		269
C 443.4
(2.2)
P 		375.8
(1)
P 		484.8
(3)
P 		158.5
(-3)
P 		326
avr 482
(3) 		331.7
(-0) 		420.4
(1.8) 		184
(-3) 		298

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 300
1 2 3 4 5 6 range
A 230.2
(-3)
P 		497.6
(3)
P 		269.6
(-2.1)
P 		265.7
(-2.2)
P 		336.2
(-0.6)
P 		292.7
(-1.6)
P 		267
B 423.8
(1.4)
P 		395
(0.2)
P 		363.1
(-1.1)
P 		315.6
(-3)
P 		443
(2.2)
P 		462.3
(3)
P 		147
C 403.9
(2.4)
P 		313.4
(0)
P 		348.5
(0.9)
P 		198.1
(-3)
P 		427.7
(3)
P 		424.8
(2.9)
P 		230
avr 352.6
(0.9) 		402
(3) 		327.1
(-0.2) 		259.8
(-3) 		402.3
(3) 		393.3
(2.6) 		143
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192446_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16825
Sequence Type Exemplar sequence
Representative Public ID W04G3.5 NCBI
Target Description W04G3.5 /REP_DB=WormBase Gene ID /WP=CE03789 /TR=Q23166 /GB=CAA92027.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=ribose-phosphate pyrophosphokinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077453(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077453 NCBI Caenorhabditis elegans W04G3.5 (W04G3.5) mRNA, complete cds. 11/11 None
GENEFINDER00000042836 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:11068688:11075698:1 11/11 None
SNAP00000042824 ENSEMBL cdna:SNAP chromosome:CEL140:X:11073586:11075698:1 11/11 None
W04G3.5 ENSEMBL cdna:known chromosome:CEL140:X:11073580:11076059:1 gene:W04G3.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:11073585-11075698(+) 100.0 100.0
Public Domain and Genome References
Gene Title ribose-phosphate pyrophosphokinase
Ensembl W04G3.5
Entrez Gene 181299 Entrez gene
SwissProt Q23166 EMBL-EBI
WormBase CE03789 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1594711_S_AT similar to phosphoribosyl pyrophosphate synthetase-associated protein 2 cfa
CANINE_2:CFA.814.1.A1_AT similar to phosphoribosyl pyrophosphate synthetase-associated protein 2 cfa
CANINE_2:CFAAFFX.27937.1.S1_AT similar to phosphoribosyl pyrophosphate synthetase-associated protein 2 cfa
DROSOPHILA_2:1629239_S_AT dm
DROSGENOME1:152008_AT dm
CHICKEN:GGA.6299.1.S1_S_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 gga
CHICKEN:GGA.6299.2.S1_S_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 gga
HG-U133_PLUS_2:203537_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 hs
HG-U133A:203537_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 hs
HG-FOCUS:203537_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 hs
HG-U133A_2:203537_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 hs
HU35KSUBA:AA453136_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 hs
U133_X3P:G4506132_3P_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 hs
HG-U95AV2:41853_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 hs
MG-U74AV2:160750_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 mm
MU11KSUBA:C77827_RC_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 mm
MU11KSUBA:C77827_RC_G_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 mm
MU11KSUBB:MSA.12730.0_S_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 mm
MG-U74BV2:164636_F_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 mm
MOE430A:1452062_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 mm
MOUSE430A_2:1452062_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 mm
MOUSE430_2:1452062_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 mm
MG-U74CV2:139007_AT Phosphoribosyl pyrophosphate synthetase-associated protein 2 (Prpsap2), mRNA mm
MU19KSUBB:TC25910_S_AT Phosphoribosyl pyrophosphate synthetase-associated protein 2 (Prpsap2), mRNA mm
RG-U34A:RC_AI231500_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 rn
RAE230A:1369978_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 rn
RAT230_2:1369978_AT phosphoribosyl pyrophosphate synthetase-associated protein 2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
9116 nucleoside metabolism inferred from electronic annotation QuickGO AmiGO
9165 nucleotide biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4749 ribose phosphate diphosphokinase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92027 Hypothetical protein W04G3.5 [Caenorhabditis elegans] ref|NP_509854.1| W04G3.5 [Caenorhabditis elegans] 0.0
blast CAE70755 Hypothetical protein CBG17504 [Caenorhabditis briggsae] 0.0
blast CAA92026 Hypothetical protein W04G3.4 [Caenorhabditis elegans] ref|NP_509853.2| AdaPTin or adaptin-related protein family member (apt-9) [Caenorhabditis elegans] 0.0
blast CAE70756 Hypothetical protein CBG17505 [Caenorhabditis briggsae] 0.0
blast CAE70709 Hypothetical protein CBG17449 [Caenorhabditis briggsae] 1.0E-172
Protein Domains
Database ID Description E-Value
scop a.4.5.MarR-like transcriptional regulators All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; MarR-like transcriptional regulators 0.629999995231628
Pfam IPR000836 EMBL-EBI Phosphoribosyltransferase 7.4E-22
Pfam IPR002014 EMBL-EBI VHS 2.9E-57
Pfam IPR000836 EMBL-EBI Phosphoribosyltransferase 7.4E-22
Sequence
Target Sequence 
>C. ELEGANS:192446_S_AT
tgcccagttgacaatcttcgtgcttcaccgttcttcctccaacacatcaagaccaacatt
ccggattacaagaatgccatcatcgttgccaagtcgccgggagtcatgaacaaggccact
tcttacgcggatcgccttcgccttggtgtggctgttattcacggagaacaaaaagacgag
gaagaatcaggtcttgaagatggacgtcaatcgccaccaccaaatgtcacttcgtacgat
tttctcccagctcaggagtccaagcagaagccaccacttacagttgttggagacgttggt
ggacggattgcaattatggtggacgacatcattgacgacgctcaatcgtttgttgccgcc
gctgaagttctgaaggctcgtggtgcatacaagatttacgtcattgccactcatggggtt
ctgtcgtctgatgctcctgcacttcttgaagcttctccaatcaccgaggtcattgttacc
aacactgttccacacgacctccagaaaatgcgttgtcacaagatcaagactgtggacgtc
tcactgatgatttgtgaggcaattcgccgcatcttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCCCAGTTGACAATCTTCGTGCTT 172 585 448 Antisense
AGAATGCCATCATCGTTGCCAAGTC 320 75 518 Antisense
TTGCCAAGTCGCCGGGAGTCATGAA 545 691 533 Antisense
CATGAACAAGGCCACTTCTTACGCG 506 209 552 Antisense
ATGTCACTTCGTACGATTTTCTCCC 197 49 671 Antisense
GAAGCCACCACTTACAGTTGTTGGA 344 345 714 Antisense
GTGGACGACATCATTGACGACGCTC 266 491 766 Antisense
GCCGCCGCTGAAGTTCTGAAGGCTC 593 285 802 Antisense
GTCATTGCCACTCATGGGGTTCTGT 11 469 847 Antisense
TCCTGCACTTCTTGAAGCTTCTCCA 593 593 882 Antisense
TTGTGAGGCAATTCGCCGCATCTTT 253 707 999 Antisense
Sequence Source Affymetrix Proprietary Database