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[192440_at] cyclic nucleotide-binding protein

Description C23H5.7 /REP_DB=WormBase Gene ID /WP=CE17439 /TR=O61827 /GB=AAC17534.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=cyclic nucleotide-binding protein
Cluster 6grp_total > 37      4grp_total > 19      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 65
1 2 3 4 range
A 12.9
(-3)
A 		47.7
(3)
A 		40.9
(1.8)
A 		15.4
(-2.6)
A 		35
B 32.4
(0)
A 		33.1
(0.1)
A 		4
(-3)
A 		60.4
(3)
A 		56
C 30.5
(-0.7)
A 		6.2
(-3)
A 		7.5
(-2.9)
A 		69.2
(3)
A 		63
avr 25.3
(-1.5) 		29
(-0.8) 		17.5
(-3) 		48.3
(3) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 46
1 2 3 4 5 6 range
A 51.5
(3)
A 		29
(-0.5)
A 		40.8
(1.3)
P 		31.6
(-0.1)
A 		24.9
(-1.1)
A 		12.8
(-3)
A 		39
B 5.8
(-3)
A 		23.9
(1.2)
A 		15.4
(-0.8)
A 		6.4
(-2.9)
A 		24.9
(1.4)
A 		31.8
(3)
A 		26
C 30.1
(0.8)
A 		37
(2)
M 		7.4
(-3)
A 		43.1
(3)
A 		25.9
(0.1)
A 		43.2
(3)
A 		36
avr 29.1
(2.4) 		30
(3) 		21.2
(-3) 		27
(1) 		25.2
(-0.3) 		29.3
(2.5) 		9
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12
1 2 3 4 range
A 4.7
(-1.3)
A 		10.4
(2.8)
A 		10.7
(3)
A 		2.3
(-3)
A 		8
B 10.3
(1.7)
A 		8.2
(0.7)
A 		0.9
(-3)
A 		12.9
(3)
A 		12
C 10.1
(2)
A 		1.8
(-3)
A 		2.6
(-2.5)
A 		11.7
(3)
A 		10
avr 8.4
(2.2) 		6.8
(-0.1) 		4.7
(-3) 		9
(3) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 13
1 2 3 4 5 6 range
A 9.5
(2.3)
A 		10.3
(3)
A 		8.9
(1.8)
P 		8
(1.1)
A 		7.5
(0.7)
A 		3.1
(-3)
A 		7
B 2
(-2.8)
A 		8
(0.7)
A 		3.7
(-1.8)
A 		1.7
(-3)
A 		10.1
(2)
A 		11.8
(3)
A 		10
C 11.2
(1.4)
A 		11.3
(1.5)
M 		1.9
(-3)
A 		8.7
(0.2)
A 		8.4
(0.1)
A 		14.5
(3)
A 		13
avr 7.6
(0.3) 		9.9
(3) 		4.8
(-3) 		6.1
(-1.5) 		8.7
(1.6) 		9.8
(2.9) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192440_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11078
Sequence Type Exemplar sequence
Representative Public ID C23H5.7 NCBI
Target Description C23H5.7 /REP_DB=WormBase Gene ID /WP=CE17439 /TR=O61827 /GB=AAC17534.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=cyclic nucleotide-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067761(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067761 NCBI Caenorhabditis elegans C23H5.7 (C23H5.7) mRNA, complete cds. 11/11 None
GENEFINDER00000034543 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:2103815:2113353:-1 11/11 None
C23H5.7 ENSEMBL cdna:known chromosome:CEL140:IV:2104055:2111604:-1 gene:C23H5.7 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:2104060-2111299(-) 99.9 99.9
Public Domain and Genome References
Gene Title cyclic nucleotide-binding protein
Ensembl C23H5.7
Entrez Gene 182823 Entrez gene
SwissProt O61827 EMBL-EBI
WormBase CE17439 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC17534 Hypothetical protein C23H5.7 [Caenorhabditis elegans] ref|NP_500162.1| C23H5.7 [Caenorhabditis elegans] 0.0
blast CAE74702 Hypothetical protein CBG22517 [Caenorhabditis briggsae] 0.0
blast AAF36062 Hypothetical protein Y76B12C.1 [Caenorhabditis elegans] ref|NP_500158.1| Y76B12C.1 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000595 EMBL-EBI Cyclic nucleotide-binding domain 3.9E-20
Pfam IPR005821 EMBL-EBI Ion transport protein 5.2E-13
Pfam IPR000595 EMBL-EBI Cyclic nucleotide-binding domain 3.9E-20
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_500162.1 4 49-71,78-100,132-154,175-197
C23H5.7 4 49-71,78-100,132-154,175-197
GENEFINDER00000034543 4 249-271,278-300,382-404,516-538
Sequence
Target Sequence 
>C. ELEGANS:192440_AT
tgtcaagcaacaagtcttctctccaaacgactatctctgccgaaaaaacgagaaagccaa
ggagttgtttatcgtgaaaaagggcaaattacgggtgatcgacgatgataccggagagga
aatgggagaactgacggagggagcgacatttggagaactatcgatagtatatgttaaggg
caacttattaggcacgcggcggtgttgttcgctacaatcagttggtttttcggacattta
tgtactttatcgagatgatgtgtcacgacttttgcaagaatttccgcaagaatataaaac
tattgtgatgaatgcacgaaacctgcttcactccagggggctcctggagaccaccgagct
tggggagatgtgcgaccccagtgaccacgaagaggctgatgacctagttctggaggaaat
gtcagttgtagagcaactcaatcggctcaatggaataattgatggtttgaatgggaatat
gaatgtgatgattttgtctttttcgaactcatgcagctactacaagcaaaaaatcaccgg
cttggaggatacatt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGTCAAGCAACAAGTCTTCTCTCCA 545 559 1323 Antisense
TCTCCAAACGACTATCTCTGCCGAA 506 607 1342 Antisense
AGGGCAACTTATTAGGCACGCGGCG 186 55 1499 Antisense
GATGATGTGTCACGACTTTTGCAAG 473 411 1576 Antisense
TGAATGCACGAAACCTGCTTCACTC 575 575 1631 Antisense
TCCAGGGGGCTCCTGGAGACCACCG 709 523 1654 Antisense
GAGACCACCGAGCTTGGGGAGATGT 607 393 1669 Antisense
CGACCCCAGTGACCACGAAGAGGCT 595 251 1695 Antisense
GAGGCTGATGACCTAGTTCTGGAGG 33 407 1714 Antisense
GTCTTTTTCGAACTCATGCAGCTAC 186 469 1818 Antisense
AAATCACCGGCTTGGAGGATACATT 569 115 1853 Antisense
Sequence Source Affymetrix Proprietary Database