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[192391_at] Zinc finger, C4 type (two domains)

Description ZK218.6 /REP_DB=WormBase Gene ID /WP=CE16706 /TR=O46003 /GB=CAB04989.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Zinc finger, C4 type (two domains)
Cluster 6grp_total > 16      4grp_total > 34      6grp_cgc > 13      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 30
1 2 3 4 range
A 2.4
(-3)
A 		19.2
(0.4)
A 		6.3
(-2.2)
A 		32
(3)
A 		30
B 2.2
(-2.9)
A 		15.8
(-0.2)
A 		31.7
(3)
A 		1.9
(-3)
A 		30
C 32.1
(3)
A 		16.8
(-0)
A 		1.8
(-3)
A 		10.2
(-1.3)
A 		30
avr 12.2
(-3) 		17.3
(3) 		13.3
(-1.7) 		14.7
(-0.1) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 37
1 2 3 4 5 6 range
A 39.1
(3)
A 		2.6
(-3)
A 		3.7
(-2.8)
A 		5.4
(-2.5)
A 		2.5
(-3)
A 		8.6
(-2)
A 		37
B 2.1
(-3)
A 		18.5
(3)
A 		4.6
(-2.1)
A 		5
(-1.9)
A 		6.7
(-1.3)
A 		3.4
(-2.5)
A 		16
C 3.7
(-2.5)
A 		15.6
(3)
A 		2.6
(-3)
A 		13.1
(1.8)
A 		4.1
(-2.3)
A 		2.8
(-2.9)
A 		13
avr 15
(3) 		12.2
(1.5) 		3.6
(-3) 		7.8
(-0.8) 		4.4
(-2.6) 		4.9
(-2.3) 		11
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 0.9
(-3)
A 		4.2
(2.2)
A 		1.6
(-1.9)
A 		4.7
(3)
A 		4
B 0.7
(-2.7)
A 		3.9
(0)
A 		7.3
(3)
A 		0.4
(-3)
A 		7
C 10.6
(3)
A 		4.8
(-0.5)
A 		0.6
(-3)
A 		1.7
(-2.3)
A 		10
avr 4.1
(2.4) 		4.3
(3) 		3.2
(-0.3) 		2.3
(-3) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 7
1 2 3 4 5 6 range
A 7.2
(3)
A 		0.9
(-2.8)
A 		0.8
(-2.9)
A 		1.4
(-2.4)
A 		0.7
(-3)
A 		2.1
(-1.7)
A 		7
B 0.7
(-3)
A 		6.2
(3)
A 		1.1
(-2.6)
A 		1.3
(-2.3)
A 		2.7
(-0.8)
A 		1.3
(-2.3)
A 		6
C 1.4
(-2)
A 		4.8
(3)
A 		0.7
(-3)
A 		2.6
(-0.2)
A 		1.3
(-2.1)
A 		0.9
(-2.7)
A 		4
avr 3.1
(1.3) 		4
(3) 		0.9
(-3) 		1.8
(-1.3) 		1.6
(-1.6) 		1.4
(-2) 		3
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192391_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13787
Sequence Type Exemplar sequence
Representative Public ID ZK218.6 NCBI
Target Description ZK218.6 /REP_DB=WormBase Gene ID /WP=CE16706 /TR=O46003 /GB=CAB04989.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Zinc finger, C4 type (two domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074933(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074933 NCBI Caenorhabditis elegans ZK218.6 (ZK218.6) mRNA, complete cds. 11/11 None
GENEFINDER00000041071 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:17105045:17107169:-1 11/11 None
ZK218.6 ENSEMBL cdna:known chromosome:CEL140:V:17106030:17107205:-1 gene:ZK218.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:17106029-17107205(-) 100.0 100.0
Public Domain and Genome References
Gene Title Zinc finger, C4 type (two domains)
Gene Symbol nhr-248
Ensembl ZK218.6
Entrez Gene 191246 Entrez gene
SwissProt O46003 EMBL-EBI
WormBase CE16706 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
3707 steroid hormone receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04989 Hypothetical protein ZK218.6 [Caenorhabditis elegans] ref|NP_507334.1| ZK218.6 [Caenorhabditis elegans] 0.0
blast CAB03504 Hypothetical protein ZK1037.5 [Caenorhabditis elegans] ref|NP_506798.1| ZK1037.5 [Caenorhabditis elegans] 1.0E-70
blast CAE74295 Hypothetical protein CBG21997 [Caenorhabditis briggsae] 8.0E-70
blast CAE74295 Hypothetical protein CBG21997 [Caenorhabditis briggsae] 2.0E-68
Protein Domains
Database ID Description E-Value
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 1.0E-23
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 1.7E-11
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 1.0E-23
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 1.7E-11
Sequence
Target Sequence 
>C. ELEGANS:192391_AT
atcaacttgatgctccggattggatttatgaatgcaacggaatggggaaattgtttcaga
ccattccgatattctaaccgttctgtgaagaaacgcatactttcggagtttgggatcgca
tctggtttaattgatcaagcattcaaaacagccacagaaactaatcaaaacgaatggtta
ttcattaataattcttgtctgagaccggatgcgttttgtactgttcacaatgattttcta
aacacacttaaacgtgagctaagtcaaccgttccgaatattgcagctggattcttttgaa
tgcgtgattttgaagaccctaatgctattgactccttcattcccggaacaatcaaagctt
cagtcaactcaaaaatcgcgtgacaaatgcacatccgaactgatgaaatgttgtctggcc
aaattcccattgag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCAACTTGATGCTCCGGATTGGAT 419 27 463 Antisense
GAAATTGTTTCAGACCATTCCGATA 174 363 509 Antisense
ATTCCGATATTCTAACCGTTCTGTG 176 7 525 Antisense
CGGAGTTTGGGATCGCATCTGGTTT 433 241 566 Antisense
ACCGGATGCGTTTTGTACTGTTCAC 16 89 666 Antisense
ACGTGAGCTAAGTCAACCGTTCCGA 586 93 714 Antisense
CAACCGTTCCGAATATTGCAGCTGG 166 187 727 Antisense
GAAGACCCTAATGCTATTGACTCCT 279 339 774 Antisense
ACTCCTTCATTCCCGGAACAATCAA 162 99 793 Antisense
ATCGCGTGACAAATGCACATCCGAA 319 37 837 Antisense
GTTGTCTGGCCAAATTCCCATTGAG 425 437 872 Antisense
Sequence Source Affymetrix Proprietary Database