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[192387_at] guanine nucleotide binding domains

Description D1081.4 /REP_DB=WormBase Gene ID /WP=CE05536 /TR=Q18957 /GB=CAB00025.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=guanine nucleotide binding domains
Cluster 6grp_high1_10_10 > 88      4grp_high_8_8 > 06      6grp_total > 98      4grp_total > 28      6grp_high1_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 46
1 2 3 4 range
A 61.5
(0.7)
M 		69.5
(3)
A 		48.7
(-3)
P 		68
(2.6)
P 		21
B 53.1
(3)
P 		49.5
(2.1)
P 		28.6
(-3)
A 		46.4
(1.4)
P 		25
C 38.4
(-3)
P 		39
(-2.9)
P 		41.9
(-2.4)
P 		74.3
(3)
A 		36
avr 51
(-0.1) 		52.7
(0.4) 		39.7
(-3) 		62.9
(3) 		23

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 192
1 2 3 4 5 6 range
A 55.8
(-2.5)
A 		43.7
(-2.9)
P 		41.1
(-3)
P 		80.2
(-1.7)
P 		196.1
(2)
P 		227.5
(3)
P 		186
B 63.1
(-2.1)
P 		43.7
(-2.7)
P 		35.5
(-3)
M 		59.6
(-2.2)
P 		185.6
(2)
P 		216.4
(3)
P 		181
C 58.1
(-2.7)
P 		48.8
(-3)
P 		82.4
(-1.9)
P 		79.6
(-2)
P 		129.6
(-0.3)
P 		227.9
(3)
P 		179
avr 59
(-2.5) 		45.4
(-3) 		53
(-2.7) 		73.1
(-2.1) 		170.4
(1.2) 		223.9
(3) 		179
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 16
1 2 3 4 range
A 22.4
(3)
M 		15.1
(-0.5)
A 		12.7
(-1.7)
P 		10
(-3)
P 		12
B 16.9
(3)
P 		12.2
(0.3)
P 		6.6
(-3)
A 		9.9
(-1.1)
P 		10
C 12.7
(-0.4)
P 		11.2
(-3)
P 		14.6
(3)
P 		12.5
(-0.7)
A 		3
avr 17.3
(3) 		12.8
(-1.2) 		11.3
(-2.5) 		10.8
(-3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 72
1 2 3 4 5 6 range
A 10.3
(-2.8)
A 		15.6
(-2.2)
P 		8.9
(-3)
P 		20.3
(-1.6)
P 		59.2
(3)
P 		55.4
(2.5)
P 		50
B 21.9
(-1.9)
P 		14.6
(-2.5)
P 		8.6
(-3)
M 		15.8
(-2.4)
P 		75.4
(2.6)
P 		80.7
(3)
P 		72
C 21.5
(-2.4)
P 		14.9
(-3)
P 		21
(-2.4)
P 		16
(-2.9)
P 		41.9
(-0.4)
P 		76.3
(3)
P 		61
avr 17.9
(-2.5) 		15
(-2.8) 		12.8
(-3) 		17.4
(-2.5) 		58.8
(1.8) 		70.8
(3) 		58
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192387_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.460
Sequence Type Exemplar sequence
Representative Public ID D1081.4 NCBI
Target Description D1081.4 /REP_DB=WormBase Gene ID /WP=CE05536 /TR=Q18957 /GB=CAB00025.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=guanine nucleotide binding domains
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059897(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059897 NCBI Caenorhabditis elegans D1081.4 (D1081.4) mRNA, complete cds. 11/11 None
GENEFINDER00000043208 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:8480681:8484407:-1 9/11 None
D1081.4 ENSEMBL cdna:known chromosome:CEL140:I:8480748:8484407:-1 gene:D1081.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000043195 2/11 Cross Hyb Matching Probes None
SNAP00000043196 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8480678-8485430(-) 100.0 100.0
Public Domain and Genome References
Gene Title guanine nucleotide binding domains
Ensembl D1081.4
Entrez Gene 183928 Entrez gene
SwissProt Q18957 EMBL-EBI
WormBase CE28544 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7264 small GTPase mediated signal transduction inferred from electronic annotation QuickGO AmiGO
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB00025 Hypothetical protein D1081.4 [Caenorhabditis elegans] ref|NP_492298.1| D1081.4 [Caenorhabditis elegans] 0.0
blast CAE67122 Hypothetical protein CBG12536 [Caenorhabditis briggsae] 1.0E-106
blast CAB00025 Hypothetical protein D1081.4 [Caenorhabditis elegans] ref|NP_492298.1| D1081.4 [Caenorhabditis elegans] 2.0E-83
blast CAE67122 Hypothetical protein CBG12536 [Caenorhabditis briggsae] 9.0E-72
blast EAL41805 ENSANGP00000026838 [Anopheles gambiae str. PEST] ref|XP_564861.1| ENSANGP00000026838 [Anopheles gambiae str. PEST] 3.0E-10
blast EAL41805 ENSANGP00000026838 [Anopheles gambiae str. PEST] ref|XP_564861.1| ENSANGP00000026838 [Anopheles gambiae str. PEST] 6.0E-10
Protein Domains
Database ID Description E-Value
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 3.7E-10
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000043208 4 381-403,423-442,447-469,489-511
Sequence
Target Sequence 
>C. ELEGANS:192387_AT
ttggtcaacttcttgccagtgatatgtatttccaaccatgcttcacagtggaacgtctat
ctggaaatcgatacttcagagttcgtttttggggaatgtcgcatgctttaatcaactgcc
acgtcgattcatcagtcgttttgccacgtgatcccgaagataactcaattcattcaaaca
tggaaatggaatttattcaaaatactacttgcaagagttacaccaacagtcttcacaaaa
ttgcgatggatattaaggcaaggaagactgatgccaatgatccataccaagttaatttta
taatgggcttacgcgagaggatttttgatgctaatatctatcaaccagtttggaatgtcg
ttggatttaaacattttgtgtttgccgccgcgtttcaatgtgaaattgcattgttataca
ttgcggcgatttttcatccacgttcaatttttccgaactatctgttattaccttacttca
atgaattcagcatatattgcgtgcgttttattcaaagtgagcgtcttgtcacctcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGGTCAACTTCTTGCCAGTGATAT 347 699 701 Antisense
ATGTATTTCCAACCATGCTTCACAG 198 47 724 Antisense
GTCGCATGCTTTAATCAACTGCCAC 134 475 798 Antisense
CTGCCACGTCGATTCATCAGTCGTT 274 237 816 Antisense
TCATCAGTCGTTTTGCCACGTGATC 689 619 829 Antisense
GAGTTACACCAACAGTCTTCACAAA 344 397 915 Antisense
TTGCCGCCGCGTTTCAATGTGAAAT 216 701 1082 Antisense
TACATTGCGGCGATTTTTCATCCAC 623 643 1117 Antisense
TTTCATCCACGTTCAATTTTTCCGA 239 673 1132 Antisense
AACTATCTGTTATTACCTTACTTCA 259 139 1156 Antisense
TCAAAGTGAGCGTCTTGTCACCTCC 442 629 1212 Antisense
Sequence Source Affymetrix Proprietary Database