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[192378_at] mitochondrial processing peptidase

Description ZC410.2 /REP_DB=WormBase Gene ID /WP=CE03806 /TR=Q23295 /GB=CAA92566.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=mitochondrial processing peptidase
Cluster 6grp_highest_10_10 > 46      6grp_high1_10_10 > 64      4grp_highest_8_8 > 24      4grp_high_8_8 > 60      6grp_highest_nonorm > 86      6grp_total > 64      4grp_total > 60      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 747
1 2 3 4 range
A 1112.5
(1.3)
P 		1117.4
(1.4)
P 		1252
(3)
P 		762.3
(-3)
P 		490
B 1159
(1.3)
P 		1268.1
(2.2)
P 		1368.6
(3)
P 		621.2
(-3)
P 		747
C 1279.4
(2.5)
P 		1330.7
(3)
P 		1166.5
(1.5)
P 		692.7
(-3)
P 		638
avr 1183.6
(2.2) 		1238.7
(2.8) 		1262.4
(3) 		692.1
(-3) 		570

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 386
1 2 3 4 5 6 range
A 906.4
(0)
P 		1012.9
(2.1)
P 		1060.4
(3)
P 		1037.6
(2.6)
P 		748.5
(-3)
P 		968.6
(1.2)
P 		312
B 921.4
(-2.1)
P 		892.9
(-3)
P 		1069.9
(2.7)
P 		939.2
(-1.5)
P 		927.6
(-1.9)
P 		1077.9
(3)
P 		185
C 877.8
(-1.2)
P 		922.5
(-0.5)
P 		1134.5
(3)
P 		999
(0.8)
P 		767.1
(-3)
P 		1110
(2.6)
P 		367
avr 901.9
(-1.1) 		942.8
(-0.2) 		1088.3
(3) 		991.9
(0.9) 		814.4
(-3) 		1052.2
(2.2) 		274
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 312
1 2 3 4 range
A 405.1
(3)
P 		242.5
(-0.3)
P 		327.3
(1.4)
P 		111.6
(-3)
P 		294
B 369.6
(3)
P 		313.2
(1.6)
P 		317.1
(1.7)
P 		132.4
(-3)
P 		237
C 423.5
(3)
P 		382.6
(2.2)
P 		406.6
(2.7)
P 		116.8
(-3)
P 		307
avr 399.4
(3) 		312.8
(1.1) 		350.3
(1.9) 		120.3
(-3) 		279

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 235
1 2 3 4 5 6 range
A 167.1
(-3)
P 		360.2
(3)
P 		230.9
(-1)
P 		263.2
(-0)
P 		225.9
(-1.2)
P 		235.8
(-0.9)
P 		193
B 320.6
(-0.2)
P 		297.2
(-1.1)
P 		259.8
(-2.6)
P 		248.8
(-3)
P 		376.9
(2)
P 		402
(3)
P 		153
C 325.3
(1.4)
P 		281.5
(-0.2)
P 		288.8
(0.1)
P 		200.9
(-3)
P 		248.2
(-1.3)
P 		371.6
(3)
P 		171
avr 271
(-1) 		313
(1.6) 		259.8
(-1.7) 		237.6
(-3) 		283.7
(-0.2) 		336.5
(3) 		99
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192378_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9831
Sequence Type Exemplar sequence
Representative Public ID ZC410.2 NCBI
Target Description ZC410.2 /REP_DB=WormBase Gene ID /WP=CE03806 /TR=Q23295 /GB=CAA92566.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=mitochondrial processing peptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069175(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069175 NCBI Caenorhabditis elegans ZC410.2 (ZC410.2) mRNA, complete cds. 11/11 None
SNAP00000030923 ENSEMBL cdna:SNAP chromosome:CEL140:IV:9074657:9076478:1 11/11 None
GENEFINDER00000030936 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:9074657:9076478:1 11/11 None
ZC410.2.2 ENSEMBL cdna:known chromosome:CEL140:IV:9074651:9076544:1 gene:ZC410.2 11/11 None
ZC410.2.1 ENSEMBL cdna:known chromosome:CEL140:IV:9074653:9076562:1 gene:ZC410.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9074337-9076484(+) 100.0 100.0
Public Domain and Genome References
Gene Title mitochondrial processing peptidase
Ensembl ZC410.2
Entrez Gene 177725 Entrez gene
SwissProt Q23295 EMBL-EBI
WormBase CE35701 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:258862_AT mitochondrial processing peptidase beta subunit, putative at
CANINE:1588678_S_AT similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP) (P-52) cfa
CANINE:1588443_S_AT similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP) (P-52) cfa
CANINE_2:CFA.290.1.A1_AT similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP) (P-52) cfa
CANINE_2:CFA.290.1.A1_S_AT similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP) (P-52) cfa
DROSOPHILA_2:1636813_S_AT dm
DROSGENOME1:151769_AT dm
CHICKEN:GGA.7638.1.A1_AT similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP) (P-52) gga
HG-FOCUS:201682_AT peptidase (mitochondrial processing) beta hs
HG-U133A:201682_AT peptidase (mitochondrial processing) beta hs
HG-U133_PLUS_2:201682_AT peptidase (mitochondrial processing) beta hs
HG-U133A_2:201682_AT peptidase (mitochondrial processing) beta hs
U133_X3P:G4758733_3P_AT peptidase (mitochondrial processing) beta hs
HG-U95AV2:32167_AT peptidase (mitochondrial processing) beta hs
HG-U95E:88115_F_AT peptidase (mitochondrial processing) beta hs
HG-U95E:88117_AT peptidase (mitochondrial processing) beta hs
HG-U95D:82474_AT Peptidase (mitochondrial processing) beta hs
HU35KSUBB:RC_T40500_AT Peptidase (mitochondrial processing) beta hs
MU11KSUBA:AA265863_S_AT peptidase (mitochondrial processing) beta mm
MG-U74AV2:94005_AT peptidase (mitochondrial processing) beta mm
MOE430A:1429709_AT peptidase (mitochondrial processing) beta mm
MOUSE430A_2:1429709_AT peptidase (mitochondrial processing) beta mm
MOUSE430_2:1429709_AT peptidase (mitochondrial processing) beta mm
MOE430A:1433729_X_AT peptidase (mitochondrial processing) beta mm
MOUSE430A_2:1433729_X_AT peptidase (mitochondrial processing) beta mm
MOUSE430_2:1433729_X_AT peptidase (mitochondrial processing) beta mm
MU11KSUBB:MSA.14148.0_S_AT Peptidase (mitochondrial processing) beta, mRNA (cDNA clone MGC:107329 IMAGE:30303695) mm
MU11KSUBB:MSA.5473.0_AT Peptidase (mitochondrial processing) beta, mRNA (cDNA clone MGC:107329 IMAGE:30303695) mm
RAE230A:1387781_AT peptidase (mitochondrial processing) beta rn
RAT230_2:1387781_AT peptidase (mitochondrial processing) beta rn
RG-U34A:D13907_AT peptidase (mitochondrial processing) beta rn
RG-U34A:D13907_G_AT peptidase (mitochondrial processing) beta rn
RG-U34C:RC_AI169688_AT peptidase (mitochondrial processing) beta rn
RAE230B:1383569_AT peptidase (mitochondrial processing) beta rn
RAT230_2:1383569_AT peptidase (mitochondrial processing) beta rn
YEAST_2:1778030_AT Smaller subunit of the mitochondrial processing protease, essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4222 metalloendopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92566 Hypothetical protein ZC410.2 [Caenorhabditis elegans] ref|NP_501576.2| ZC410.2 [Caenorhabditis elegans] 0.0
blast CAE74099 Hypothetical protein CBG21759 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR007863 EMBL-EBI Peptidase M16, C-terminal 8.9E-45
Pfam IPR001431 EMBL-EBI Peptidase M16, insulinase-like 8.6E-68
Sequence
Target Sequence 
>C. ELEGANS:192378_AT
tcgaggtgacattccagatcttccaatgttgtacggagcgatggttgtcgaaggagtatc
ttggacccatgaagataatcttgcccttatggtggctaatacgctaatgggtgaatacga
tcgtatgcgtggattcggcgtgaatgctccaactcgcttggctgaaaaattgtcacaaga
cgcaggaattgaggttttccaatcatttaacacgtgctataaagagacaggattagttgg
aacttatttcgtagctgctccggaatccatcgacaatcttattgattcagttcttcaaca
atgggtttggcttgcgaacaacattgatgaagcagcggttgatcgtgccaagcgctccct
gcatacgaatctactcctaatgctcgatggctcaactccagtctgtgaagatattggtcg
acaactcctttgctacggtcgtcggataccaactccagaattacatgcccgaatcgaatc
aatcacagtccagcagctccgagatgtttgccgacgtgtattccttgaaggacaggtctc
tgcagcagttg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCGAGGTGACATTCCAGATCTTCCA 278 603 855 Antisense
GATAATCTTGCCCTTATGGTGGCTA 536 421 928 Antisense
TATTTCGTAGCTGCTCCGGAATCCA 621 651 1099 Antisense
AGCAGCGGTTGATCGTGCCAAGCGC 270 77 1185 Antisense
TCCCTGCATACGAATCTACTCCTAA 468 597 1210 Antisense
TACTCCTAATGCTCGATGGCTCAAC 607 645 1226 Antisense
ATATTGGTCGACAACTCCTTTGCTA 325 19 1265 Antisense
TTGCTACGGTCGTCGGATACCAACT 251 663 1284 Antisense
ACCAACTCCAGAATTACATGCCCGA 190 85 1302 Antisense
ATGTTTGCCGACGTGTATTCCTTGA 688 45 1358 Antisense
GAAGGACAGGTCTCTGCAGCAGTTG 286 333 1381 Antisense
Sequence Source Affymetrix Proprietary Database