[Home] | [Total List]

[192374_s_at] integrin-linked kinase

Description C29F9.7 /REP_DB=WormBase Gene ID /WP=CE19706 /GEN=pat-4 /TR=Q9TZC4 /GB=AAC68756.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=integrin-linked kinase
Cluster 6grp_highest_10_10 > 03      6grp_high1_10_10 > 22      4grp_highest_8_8 > 08      4grp_high_8_8 > 53      6grp_highest_nonorm > 31      6grp_total > 12      4grp_total > 51      6grp_highest_sub > De      6grp_cgc > 61      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Hat      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1465
1 2 3 4 range
A 928
(-0.3)
P 		1699.7
(3)
P 		1318.6
(1.4)
P 		283.7
(-3)
P 		1416
B 953.3
(0.1)
P 		1628.8
(3)
P 		1308.5
(1.6)
P 		234.4
(-3)
P 		1394
C 940.2
(0.2)
P 		1516.5
(3)
P 		1262
(1.7)
P 		297.5
(-3)
P 		1219
avr 940.5
(-0) 		1615
(3) 		1296.4
(1.6) 		271.9
(-3) 		1343

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 701
1 2 3 4 5 6 range
A 1136.4
(2.5)
P 		1191.9
(3)
P 		1042.4
(1.6)
P 		981.7
(1)
P 		869.8
(-0)
P 		554.8
(-3)
P 		637
B 1028.2
(1.8)
P 		1163.6
(3)
P 		1131.6
(2.7)
P 		894
(0.6)
P 		1050.7
(2)
P 		490.5
(-3)
P 		673
C 1107.3
(3)
P 		1092.4
(2.8)
P 		1101.6
(2.9)
P 		875.3
(0.6)
P 		996.5
(1.9)
P 		520
(-3)
P 		587
avr 1090.6
(2.4) 		1149.3
(3) 		1091.9
(2.5) 		917
(0.8) 		972.3
(1.3) 		521.8
(-3) 		628
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 398
1 2 3 4 range
A 337.9
(2.4)
P 		369
(3)
P 		344.7
(2.6)
P 		41.5
(-3)
P 		328
B 304
(1.3)
P 		402.3
(3)
P 		303.2
(1.3)
P 		50
(-3)
P 		352
C 311.2
(1)
P 		436
(2.9)
P 		439.8
(3)
P 		50.2
(-3)
P 		390
avr 317.7
(1.6) 		402.4
(3) 		362.6
(2.3) 		47.2
(-3) 		355

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 292
1 2 3 4 5 6 range
A 209.5
(-1.5)
P 		423.9
(3)
P 		227
(-1.1)
P 		249
(-0.6)
P 		262.5
(-0.4)
P 		135.1
(-3)
P 		289
B 357.8
(1.3)
P 		387.3
(2)
P 		274.8
(-0.7)
P 		236.8
(-1.7)
P 		426.9
(3)
P 		182.9
(-3)
P 		244
C 410.4
(3)
P 		333.3
(1)
P 		280.4
(-0.3)
P 		176
(-3)
P 		322.5
(0.8)
P 		174.1
(-3)
P 		236
avr 325.9
(1.5) 		381.5
(3) 		260.7
(-0.3) 		220.6
(-1.4) 		337.3
(1.8) 		164
(-3) 		218
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192374_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8301
Sequence Type Exemplar sequence
Representative Public ID C29F9.7 NCBI
Target Description C29F9.7 /REP_DB=WormBase Gene ID /WP=CE19706 /GEN=pat-4 /TR=Q9TZC4 /GB=AAC68756.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=integrin-linked kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064738(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064738 NCBI Caenorhabditis elegans Paralysed Arrest at Two-fold family member (pat-4) (pat-4) mRNA, complete cds. 11/11 A 
SNAP00000042026 ENSEMBL cdna:SNAP chromosome:CEL140:III:89642:94802:-1 11/11 None
GENEFINDER00000042035 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:90115:92276:-1 11/11 None
C29F9.7.1 ENSEMBL cdna:known chromosome:CEL140:III:89017:94808:-1 gene:C29F9.7 11/11 A 
C29F9.7.2 ENSEMBL cdna:known chromosome:CEL140:III:89460:95255:-1 gene:C29F9.7 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:89641-94802(-) 100.0 100.0
Public Domain and Genome References
Gene Title integrin-linked kinase
Gene Symbol pat-4
Ensembl C29F9.7
Entrez Gene 175175 Entrez gene
SwissProt Q9TZC4 EMBL-EBI
WormBase CE19706 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1606132_S_AT similar to integrin linked kinase cfa
CANINE:1591660_AT similar to integrin linked kinase cfa
CANINE_2:CFA.465.1.S1_S_AT similar to integrin linked kinase cfa
CANINE_2:CFA.465.2.S1_S_AT similar to integrin linked kinase cfa
CANINE_2:CFA.465.3.S1_S_AT similar to integrin linked kinase cfa
DROSOPHILA_2:1625014_AT Integrin linked kinase dm
DROSGENOME1:154284_AT Integrin linked kinase dm
CHICKEN:GGA.3404.1.S1_A_AT integrin-linked kinase gga
HG-U133A:201234_AT integrin-linked kinase hs
HG-U133_PLUS_2:201234_AT integrin-linked kinase hs
HG-U133A_2:201234_AT integrin-linked kinase hs
HG-FOCUS:201234_AT integrin-linked kinase hs
HUGENEFL:U40282_AT integrin-linked kinase hs
U133_X3P:G4758605_3P_S_AT integrin-linked kinase hs
HG-U95AV2:35365_AT integrin-linked kinase hs
HG-U133_PLUS_2:235906_AT Integrin-linked kinase-2 hs
HG-U133B:235906_AT Integrin-linked kinase-2 hs
HU35KSUBB:RC_T98195_AT Integrin-linked kinase-2 hs
HU35KSUBC:RC_Z41239_S_AT Integrin-linked kinase-2 hs
U133_X3P:HS.18252.0.A1_3P_AT Integrin-linked kinase-2 hs
U133_X3P:HS.106960.0.S1_3P_AT Integrin-linked kinase-2 hs
HG-U133_PLUS_2:235135_AT Integrin-linked kinase-2 hs
HG-U133B:235135_AT Integrin-linked kinase-2 hs
HG-U95B:47407_AT Integrin-linked kinase-2 hs
HG-U95C:65407_F_AT Integrin-linked kinase-2 hs
HG-U95C:65408_F_AT Integrin-linked kinase-2 hs
MU11KSUBB:MSA.9013.0_S_AT integrin linked kinase mm
MG-U74AV2:101499_AT integrin linked kinase mm
MOE430A:1449942_A_AT integrin linked kinase mm
MOUSE430A_2:1449942_A_AT integrin linked kinase mm
MOUSE430_2:1449942_A_AT integrin linked kinase mm
MU19KSUBC:TC36336_AT Integrin linked kinase, mRNA (cDNA clone MGC:5823 IMAGE:3601214) mm
RG-U34C:RC_AI176814_AT integrin linked kinase rn
RAE230A:1387777_AT integrin linked kinase rn
RAT230_2:1387777_AT integrin linked kinase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
6468 protein amino acid phosphorylation inferred from sequence similarity QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5912 adherens junction inferred from direct assay QuickGO AmiGO
8305 integrin complex inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC68756 Paralysed arrest at two-fold protein 4 [Caenorhabditis elegans] ref|NP_497139.1| Paralysed Arrest at Two-fold family member (pat-4) [Caenorhabditis elegans] 0.0
blast CAB77052 putative integrin-linked kinase [Caenorhabditis elegans] 0.0
blast EAL29808 GA10358-PA [Drosophila pseudoobscura] 1.0E-169
Protein Domains
Database ID Description E-Value
Pfam IPR002110 EMBL-EBI Ankyrin 3.7E-7
Pfam IPR002110 EMBL-EBI Ankyrin 1.2E-7
Pfam IPR002110 EMBL-EBI Ankyrin 1.3E-11
Pfam IPR000719 EMBL-EBI Protein kinase 9.8E-12
Pfam IPR000719 EMBL-EBI Protein kinase 5.2E-13
Pfam IPR000719 EMBL-EBI Protein kinase 1.1E-11
Pfam IPR000719 EMBL-EBI Protein kinase 2.0E-6
Sequence
Target Sequence 
>C. ELEGANS:192374_S_AT
gaacttggtgatcatctcgcagtacatgccatttggaagcctgtataacgtgctccacga
gcaaagttctgtcgtcattgatcacgggcaagccgtcagattcgcgttggacattgctag
aggaatgagctacttgcacagtttggaccctatgcttttgaggttctacctctcctccaa
acacgttgtagtcgacgaggagctcaccgccaaactctcaatggcagatacgaaattctc
gttccaagaggtcggaaaagcctattcgcctgcctggatgagcccagaagccttgtcacg
ggctccagaagacttgaatattagagctgccgatatgtggtcatttgctatattgttgtg
ggagctgaacactcgtgaggtcccatt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAACTTGGTGATCATCTCGCAGTAC 444 349 846 Antisense
GGAAGCCTGTATAACGTGCTCCACG 225 531 880 Antisense
GTCGTCATTGATCACGGGCAAGCCG 230 473 916 Antisense
GCAAGCCGTCAGATTCGCGTTGGAC 325 321 933 Antisense
CACAGTTTGGACCCTATGCTTTTGA 466 183 982 Antisense
CTCTCCTCCAAACACGTTGTAGTCG 539 231 1015 Antisense
AGGTCGGAAAAGCCTATTCGCCTGC 103 51 1094 Antisense
GCCTGCCTGGATGAGCCCAGAAGCC 703 281 1113 Antisense
TTGTCACGGGCTCCAGAAGACTTGA 639 701 1138 Antisense
GAGCTGCCGATATGTGGTCATTTGC 329 387 1169 Antisense
AGCTGAACACTCGTGAGGTCCCATT 49 81 1208 Antisense
Sequence Source Affymetrix Proprietary Database