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[192370_at] adenine phosphoribosyltransferase

Description T19B4.3 /REP_DB=WormBase Gene ID /WP=CE13740 /TR=P91455 /GB=AAB37633.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=adenine phosphoribosyltransferase
Cluster 6grp_highest_10_10 > 06      6grp_high1_10_10 > 60      4grp_highest_8_8 > 13      4grp_high_8_8 > 23      6grp_highest_nonorm > 37      6grp_total > 60      4grp_total > 24      6grp_highest_sub > 04      6grp_high1_sub > 04      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3264
1 2 3 4 range
A 4695.4
(-3)
P 		6451.2
(0.8)
P 		6933.2
(1.9)
P 		7436.5
(3)
P 		2741
B 4759.6
(-3)
P 		6474.8
(1)
P 		6542.4
(1.1)
P 		7346.8
(3)
P 		2587
C 5283.7
(-2.1)
P 		4798.2
(-3)
P 		6400.8
(0)
P 		7959.5
(3)
P 		3161
avr 4912.9
(-3) 		5908.1
(-0.8) 		6625.5
(0.9) 		7580.9
(3) 		2668

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3637
1 2 3 4 5 6 range
A 5194.2
(-0.4)
P 		4545.6
(-1.6)
P 		4913.6
(-0.9)
P 		7023.2
(3)
P 		3805.4
(-3)
P 		4508.9
(-1.7)
P 		3218
B 4262.5
(-0.8)
P 		5179.4
(3)
P 		5061.8
(2.5)
P 		5097.7
(2.7)
P 		4747.6
(1.2)
P 		3712.9
(-3)
P 		1467
C 3842.5
(-1.5)
P 		5159.8
(3)
P 		4299.2
(0.1)
P 		4836.4
(1.9)
P 		3549.8
(-2.4)
P 		3386.3
(-3)
P 		1774
avr 4433.1
(-1.1) 		4961.6
(0.7) 		4758.2
(-0) 		5652.4
(3) 		4034.3
(-2.4) 		3869.4
(-3) 		1783
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1142
1 2 3 4 range
A 1709.6
(2.1)
P 		1400.4
(-0.4)
P 		1812.5
(3)
P 		1088.6
(-3)
P 		724
B 1517.8
(-2.9)
P 		1599.1
(3)
P 		1516
(-3)
P 		1565.6
(0.6)
P 		83
C 1749
(-0.3)
P 		1379.5
(-2.7)
P 		2230.9
(3)
P 		1342.1
(-3)
P 		889
avr 1658.8
(0.8) 		1459.7
(-1.5) 		1853.1
(3) 		1332.1
(-3) 		521

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 971
1 2 3 4 5 6 range
A 957.5
(-3)
P 		1616.6
(1.8)
P 		1070.1
(-2.2)
P 		1781.3
(3)
P 		1148.3
(-1.6)
P 		1097.8
(-2)
P 		824
B 1483.1
(-0.8)
P 		1724
(1.2)
P 		1229.2
(-3)
P 		1350.2
(-2)
P 		1928.9
(3)
P 		1384.5
(-1.7)
P 		700
C 1424.3
(1.5)
P 		1574.4
(3)
P 		1094.2
(-1.8)
P 		972.6
(-3)
P 		1148.7
(-1.2)
P 		1133.6
(-1.4)
P 		602
avr 1288.3
(-1.1) 		1638.3
(3) 		1131.2
(-3) 		1368
(-0.2) 		1408.6
(0.3) 		1205.3
(-2.1) 		507
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192370_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1199
Sequence Type Exemplar sequence
Representative Public ID T19B4.3 NCBI
Target Description T19B4.3 /REP_DB=WormBase Gene ID /WP=CE13740 /TR=P91455 /GB=AAB37633.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=adenine phosphoribosyltransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059262(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059262 NCBI Caenorhabditis elegans T19B4.3 (T19B4.3) mRNA, complete cds. 11/11 None
SNAP00000019537 ENSEMBL cdna:SNAP chromosome:CEL140:I:5678648:5679773:1 11/11 None
GENEFINDER00000019546 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:5678648:5679773:1 11/11 None
T19B4.3.1 ENSEMBL cdna:known chromosome:CEL140:I:5678635:5679858:1 gene:T19B4.3 11/11 None
T19B4.3.2 ENSEMBL cdna:known chromosome:CEL140:I:5678641:5679858:1 gene:T19B4.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:5678647-5679773(+) 100.0 100.0
Public Domain and Genome References
Gene Title adenine phosphoribosyltransferase
Ensembl T19B4.3
Entrez Gene 172232 Entrez gene
SwissProt P91455 EMBL-EBI
WormBase CE13740 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:254328_AT adenine phosphoribosyltransferase, putative at
CANINE:1599423_S_AT similar to Adenine phosphoribosyltransferase (APRT) cfa
CANINE:1599422_AT similar to Adenine phosphoribosyltransferase (APRT) cfa
CANINE:1591494_AT similar to Adenine phosphoribosyltransferase (APRT) cfa
CANINE_2:CFA.14529.1.S1_A_AT similar to Adenine phosphoribosyltransferase (APRT) cfa
CANINE_2:CFA.14529.2.A1_X_AT similar to Adenine phosphoribosyltransferase (APRT) cfa
CANINE_2:CFAAFFX.30404.1.S1_S_AT similar to Adenine phosphoribosyltransferase (APRT) cfa
DROSOPHILA_2:1628492_AT Adenine phosphoribosyltransferase dm
DROSGENOME1:143076_AT Adenine phosphoribosyltransferase dm
HG-U133_PLUS_2:213892_S_AT adenine phosphoribosyltransferase hs
HG-U133A_2:213892_S_AT adenine phosphoribosyltransferase hs
HG-FOCUS:213892_S_AT adenine phosphoribosyltransferase hs
HG-U133A:213892_S_AT adenine phosphoribosyltransferase hs
HG-U133A:203219_S_AT adenine phosphoribosyltransferase hs
HG-U133_PLUS_2:203219_S_AT adenine phosphoribosyltransferase hs
HG-U133A_2:203219_S_AT adenine phosphoribosyltransferase hs
HUGENEFL:Y00486_RNA1_AT adenine phosphoribosyltransferase hs
U133_X3P:HS.28914.1.S1_3P_A_AT adenine phosphoribosyltransferase hs
HG-U95AV2:34310_AT adenine phosphoribosyltransferase hs
MG-U74AV2:93283_AT adenine phosphoribosyl transferase mm
MOE430A:1451703_S_AT adenine phosphoribosyl transferase mm
MOUSE430A_2:1451703_S_AT adenine phosphoribosyl transferase mm
MOUSE430_2:1451703_S_AT adenine phosphoribosyl transferase mm
MU11KSUBA:M11310_S_AT adenine phosphoribosyl transferase mm
MG-U74AV2:161330_R_AT adenine phosphoribosyl transferase mm
MOE430A:1423801_A_AT adenine phosphoribosyl transferase mm
MOUSE430A_2:1423801_A_AT adenine phosphoribosyl transferase mm
MOUSE430_2:1423801_A_AT adenine phosphoribosyl transferase mm
MG-U74AV2:93282_AT adenine phosphoribosyl transferase mm
RG-U34A:RC_AI177096_AT adenine phosphoribosyl transferase (predicted) rn
RAE230A:1371244_AT adenine phosphoribosyl transferase (predicted) rn
RAT230_2:1371244_AT adenine phosphoribosyl transferase (predicted) rn
YEAST_2:1771956_AT Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6168 adenine salvage inferred from electronic annotation QuickGO AmiGO
9116 nucleoside metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3999 adenine phosphoribosyltransferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB37633 Hypothetical protein T19B4.3 [Caenorhabditis elegans] ref|NP_491663.1| T19B4.3 [Caenorhabditis elegans] gb|AAG50224.1| adenine phosphoribosyltransferase [Caenorhabditis elegans] sp|P91455|APT_CAEEL Adenine phosphoribosyltransferase (APRT) 1.0E-100
blast CAE68936 Hypothetical protein CBG14916 [Caenorhabditis briggsae] 2.0E-93
Protein Domains
Database ID Description E-Value
Pfam IPR000836 EMBL-EBI Phosphoribosyltransferase 2.0E-43
Sequence
Target Sequence 
>C. ELEGANS:192370_AT
tgacacttccacgtttcgatcaaatccgacccaagatcgagcaacacatccgggaggtga
aggatttcccgaagaaaggcattaattttcgtgatataatgccattgttcacaaatcctc
aactcgtcaacgagctctgtgttgtcattgccgatcacgttcgtcatacagttggacacg
tggattcagttgctggcttagaggcacggggattcctattcggaccacaagttgccattc
agctgggtgttccatttgtgccaatccgcaagaagggaaagctcccaggagcaacgattg
aagcatcgtatgtgaaagaatatggagaggatcgggttgaaattcaagaaggagcaatta
aaaatggggatattgtgttcttgatcgatgacttgttggctactggaggcactttaagag
ctgccaccgatctagtcgtgaaagctggtggaaaagtcggtgaggcatttgttctcatag
aactggcaccattgaatggtcgttccaagcttccgga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGACACTTCCACGTTTCGATCAAAT 78 573 14 Antisense
GACCCAAGATCGAGCAACACATCCG 606 381 41 Antisense
TCACAAATCCTCAACTCGTCAACGA 304 629 122 Antisense
GCTCTGTGTTGTCATTGCCGATCAC 3 301 147 Antisense
TGCCGATCACGTTCGTCATACAGTT 486 583 162 Antisense
GCTGGCTTAGAGGCACGGGGATTCC 311 293 205 Antisense
GGACCACAAGTTGCCATTCAGCTGG 11 523 235 Antisense
TCAGCTGGGTGTTCCATTTGTGCCA 433 625 252 Antisense
GACTTGTTGGCTACTGGAGGCACTT 154 371 403 Antisense
GCTGCCACCGATCTAGTCGTGAAAG 392 297 433 Antisense
TGAATGGTCGTTCCAAGCTTCCGGA 668 575 506 Antisense
Sequence Source Affymetrix Proprietary Database