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[192364_s_at] kinesin-like protein

Description F23B12.8 /REP_DB=WormBase Gene ID /WP=CE09600 /GEN=bmk-1 /TR=Q9XTM0 /GB=CAB01170.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=kinensin-like protein
Cluster 6grp_high1_10_10 > 77      6grp_total > 68      4grp_total > 51      6grp_cgc > 39      6grp_high1_sub > Da      6grp_cgc_sub > Cu      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 420
1 2 3 4 range
A 317.4
(-0.1)
P 		520.7
(3)
P 		263.8
(-0.9)
P 		121.1
(-3)
A 		400
B 267.2
(-0.4)
P 		480.6
(3)
P 		266.1
(-0.4)
P 		101.2
(-3)
A 		379
C 270.8
(-0.3)
P 		420.9
(3)
P 		321
(0.8)
P 		147
(-3)
A 		274
avr 285.1
(-0.2) 		474.1
(3) 		283.6
(-0.3) 		123.1
(-3) 		351

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 826
1 2 3 4 5 6 range
A 376.7
(-1.8)
P 		295.2
(-2.4)
P 		208.2
(-3)
A 		275.7
(-2.5)
P 		452.7
(-1.2)
P 		1034.6
(3)
P 		826
B 455.8
(-1.1)
P 		286.4
(-2.6)
P 		246.2
(-3)
P 		300.8
(-2.5)
P 		397.9
(-1.6)
P 		909.1
(3)
P 		663
C 307.1
(-2.4)
P 		286.5
(-2.5)
P 		262.8
(-2.7)
A 		225.6
(-3)
P 		414.2
(-1.6)
P 		1007
(3)
P 		781
avr 379.9
(-1.9) 		289.4
(-2.6) 		239.1
(-3) 		267.4
(-2.8) 		421.6
(-1.5) 		983.6
(3) 		745
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 115.6
(3)
P 		113
(2.8)
P 		69
(0.1)
P 		17.7
(-3)
A 		98
B 85.2
(0.9)
P 		118.7
(3)
P 		61.7
(-0.5)
P 		21.6
(-3)
A 		97
C 89.6
(1)
P 		121
(3)
P 		111.9
(2.4)
P 		24.8
(-3)
A 		96
avr 96.8
(1.7) 		117.6
(3) 		80.9
(0.7) 		21.4
(-3) 		96

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 294
1 2 3 4 5 6 range
A 69.4
(-2.3)
P 		105
(-1.3)
P 		45.3
(-3)
A 		69.9
(-2.3)
P 		136.6
(-0.3)
P 		251.9
(3)
P 		207
B 158.6
(-0.9)
P 		95.3
(-2.2)
P 		59.8
(-3)
P 		79.7
(-2.6)
P 		161.6
(-0.8)
P 		339
(3)
P 		279
C 113.8
(-1.6)
P 		87.4
(-2.1)
P 		66.9
(-2.6)
A 		45.4
(-3)
P 		134
(-1.2)
P 		337.1
(3)
P 		292
avr 113.9
(-1.7) 		95.9
(-2.1) 		57.3
(-3) 		65
(-2.8) 		144.1
(-0.9) 		309.3
(3) 		252
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192364_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13022
Sequence Type Exemplar sequence
Representative Public ID F23B12.8 NCBI
Target Description F23B12.8 /REP_DB=WormBase Gene ID /WP=CE09600 /GEN=bmk-1 /TR=Q9XTM0 /GB=CAB01170.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=kinensin-like protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074181(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074181 NCBI Caenorhabditis elegans BiMC related Kinase family member (bmk-1) (bmk-1) mRNA, complete cds. 11/11 A 
F23B12.8.2 ENSEMBL cdna:known chromosome:CEL140:V:14455905:14459327:-1 gene:F23B12.8 11/11 A 
F23B12.8.1 ENSEMBL cdna:known chromosome:CEL140:V:14455905:14459479:-1 gene:F23B12.8 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
AB024428 11/11 Negative Strand Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:14455990-14459304(-) 100.0 100.0
Public Domain and Genome References
Gene Title kinesin-like protein
Gene Symbol bmk-1
Ensembl F23B12.8
Entrez Gene 179948 Entrez gene
SwissProt Q9XTM0 EMBL-EBI
WormBase CE09600 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:252548_AT kinesin motor protein-related at
CANINE:1604305_AT similar to kinesin family member 11 cfa
CANINE_2:CFAAFFX.12118.1.S1_S_AT similar to kinesin family member 11 cfa
DROSOPHILA_2:1624620_AT Kinesin-like protein at 61F dm
DROSGENOME1:153851_AT Kinesin-like protein at 61F dm
HG-U133A:204444_AT kinesin family member 11 hs
HG-U133_PLUS_2:204444_AT kinesin family member 11 hs
HG-FOCUS:204444_AT kinesin family member 11 hs
HG-U133A_2:204444_AT kinesin family member 11 hs
HU35KSUBC:RC_AA453159_S_AT kinesin family member 11 hs
HUGENEFL:X85137_S_AT kinesin family member 11 hs
HUGENEFL:U37426_AT kinesin family member 11 hs
U133_X3P:G13699823_3P_AT kinesin family member 11 hs
HG-U95AV2:40726_AT kinesin family member 11 hs
HG-U95D:91448_AT kinesin family member 11 hs
MG-U74AV2:99541_AT kinesin family member 11 mm
MG-U74CV2:170746_F_AT kinesin family member 11 mm
MOE430A:1435306_A_AT kinesin family member 11 mm
MOUSE430A_2:1435306_A_AT kinesin family member 11 mm
MOUSE430_2:1435306_A_AT kinesin family member 11 mm
MOE430A:1452315_AT kinesin family member 11 mm
MOUSE430A_2:1452315_AT kinesin family member 11 mm
MOUSE430_2:1452315_AT kinesin family member 11 mm
MOE430A:1452314_AT kinesin family member 11 mm
MOUSE430A_2:1452314_AT kinesin family member 11 mm
MOUSE430_2:1452314_AT kinesin family member 11 mm
MU19KSUBC:TC37332_AT Kinesin-related mitotic motor protein mm
MU19KSUBC:TC41164_AT Kinesin-related mitotic motor protein mm
MU19KSUBC:TC41164_G_AT Kinesin-related mitotic motor protein mm
RG-U34A:AF035955_AT kinesin-like 1 rn
YEAST_2:1773899_AT Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p Sc
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5875 microtubule associated complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3774 motor activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01170 Hypothetical protein F23B12.8 [Caenorhabditis elegans] emb|CAB01153.1| Hypothetical protein F23B12.8 [Caenorhabditis elegans] ref|NP_506582.1| BiMC related Kinase family member (bmk-1) [Caenorhabditis elegans] gb|AAG03081.1| bimC kinesin BMK-1 [Caenorhabditis elegans] dbj|BAC19818.1| kinesin like protein KLP-14 [Caenorhabditis elegans] 0.0
blast CAE66550 Hypothetical protein CBG11862 [Caenorhabditis briggsae] 0.0
blast NP_999660 KRP170 [Strongylocentrotus purpuratus] gb|AAG18583.1| KRP170 [Strongylocentrotus purpuratus] 1.0E-122
Protein Domains
Database ID Description E-Value
Pfam IPR001752 EMBL-EBI Kinesin, motor region 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192364_S_AT
tcaaggtcgctctcaagtcattttcggatgaggctgaagctacgcgtggagaggcaaggg
agttttcgaacaccttgaaaagcaggttctcggcaaccagtgaaaagtgcaaagtaactg
gcgagctggtttcggattgcaccaagaaagcaacagacgaattgagttcgctcctcgatg
aattcacgaaatcgactattgtcgtgacaaaggagtcggccgccgttgtcaattctgttg
ttctggttcacgtggacccatcagtgaatgtcccacaaagaattcttccatcgttcccac
tcgtctcggagttgaatcagccagtcgaacccgaagttcttcttggatttggagaaggaa
atgacgactttgacaccgatgaacttgccacaaagaagcgtcgtgtcacatccttcgtcc
gccgagacagtcttctcgaaactacgaacaatttcctcagtccttcgtcgattataa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCAAGGTCGCTCTCAAGTCATTTTC 492 631 2366 Antisense
GAGGCTGAAGCTACGCGTGGAGAGG 32 407 2395 Antisense
AAAGCAGGTTCTCGGCAACCAGTGA 79 125 2444 Antisense
AGTAACTGGCGAGCTGGTTTCGGAT 545 57 2478 Antisense
TGAGTTCGCTCCTCGATGAATTCAC 495 567 2528 Antisense
ACAAAGGAGTCGGCCGCCGTTGTCA 616 109 2572 Antisense
CCGCCGTTGTCAATTCTGTTGTTCT 704 261 2585 Antisense
TTCTGTTGTTCTGGTTCACGTGGAC 96 693 2598 Antisense
GTGGACCCATCAGTGAATGTCCCAC 262 491 2617 Antisense
ACTACGAACAATTTCCTCAGTCCTT 418 101 2806 Antisense
TTCCTCAGTCCTTCGTCGATTATAA 68 699 2818 Antisense
Sequence Source Affymetrix Proprietary Database