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[192351_s_at] Core histones H2A, H2B, H3 and H4

Description W05B10.1 /REP_DB=WormBase Gene ID /WP=CE06544 /TR=Q27532 /GB=CAA98963.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Core histones H2A, H2B, H3 and H4
Cluster 6grp_highest_10_10 > 79      6grp_high1_10_10 > 98      4grp_highest_8_8 > 12      4grp_high_8_8 > 39      6grp_highest_nonorm > 99      6grp_total > 97      4grp_total > 40      6grp_highest_sub > In      6grp_high1_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 358
1 2 3 4 range
A 384.5
(-3)
P 		467.5
(-1.1)
P 		651.7
(3)
P 		585.7
(1.5)
P 		267
B 385
(-3)
P 		573.1
(0.4)
P 		717.8
(3)
P 		617.1
(1.2)
P 		333
C 359.5
(-3)
P 		540.4
(3)
P 		489.3
(1.3)
P 		399.2
(-1.7)
P 		181
avr 376.3
(-3) 		527
(0.7) 		619.6
(3) 		534
(0.9) 		243

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2184
1 2 3 4 5 6 range
A 299.1
(-3)
P 		337.5
(-2.9)
P 		471.9
(-2.5)
P 		879.1
(-1.3)
P 		1702
(1)
P 		2398.4
(3)
P 		2099
B 214.2
(-3)
P 		375.4
(-2.5)
P 		573.5
(-2)
P 		881
(-1.1)
P 		1716.9
(1.3)
P 		2321.3
(3)
P 		2107
C 241.6
(-3)
P 		371.2
(-2.6)
P 		601
(-2)
P 		839.1
(-1.3)
P 		1687.1
(1)
P 		2387.7
(3)
P 		2146
avr 251.6
(-3) 		361.4
(-2.7) 		548.8
(-2.2) 		866.4
(-1.3) 		1702
(1.1) 		2369.1
(3) 		2118
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 140
(0.8)
P 		101.5
(-1.9)
P 		170.4
(3)
P 		85.7
(-3)
P 		85
B 122.8
(-3)
P 		141.5
(-0.4)
P 		166.3
(3)
P 		131.5
(-1.8)
P 		44
C 119
(0)
P 		155.4
(2.1)
P 		170.5
(3)
P 		67.3
(-3)
P 		103
avr 127.3
(-0.4) 		132.8
(0.1) 		169.1
(3) 		94.8
(-3) 		74

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 811
1 2 3 4 5 6 range
A 55.1
(-3)
P 		120
(-2.3)
P 		102.8
(-2.5)
P 		223
(-1.1)
P 		513.6
(2.2)
P 		583.9
(3)
P 		529
B 74.5
(-3)
P 		125
(-2.6)
P 		139.3
(-2.5)
P 		233.3
(-1.8)
P 		697.6
(1.7)
P 		865.6
(3)
P 		791
C 89.6
(-3)
P 		113.3
(-2.8)
P 		153
(-2.5)
P 		168.7
(-2.3)
P 		545.9
(0.9)
P 		799.3
(3)
P 		710
avr 73.1
(-3) 		119.4
(-2.6) 		131.7
(-2.5) 		208.3
(-1.8) 		585.7
(1.5) 		749.6
(3) 		677
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192351_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14048
Sequence Type Exemplar sequence
Representative Public ID W05B10.1 NCBI
Target Description W05B10.1 /REP_DB=WormBase Gene ID /WP=CE06544 /TR=Q27532 /GB=CAA98963.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Core histones H2A, H2B, H3 and H4
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073763(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073763 NCBI Caenorhabditis elegans W05B10.1 (W05B10.1) mRNA, complete cds. 11/11 None
SNAP00000011551 ENSEMBL cdna:SNAP chromosome:CEL140:V:12662459:12662916:-1 11/11 None
GENEFINDER00000011553 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12662459:12662916:-1 11/11 None
W05B10.1 ENSEMBL cdna:known chromosome:CEL140:V:12662296:12662920:-1 gene:W05B10.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000013875 1/11 Cross Hyb Matching Probes None
K03A1.1 1/11 Cross Hyb Matching Probes B 
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12662458-12662916(-) 100.0 100.0
Public Domain and Genome References
Gene Title Core histones H2A, H2B, H3 and H4
Ensembl W05B10.1
Entrez Gene 179734 Entrez gene
SwissProt Q27532 EMBL-EBI
WormBase CE06544 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1587087_AT similar to H3 histone, family 3B cfa
CANINE:1585827_AT similar to H3 histone, family 3B cfa
CANINE_2:CFA.4151.1.S1_S_AT similar to H3 histone, family 3B cfa
CANINE_2:CFAAFFX.14172.1.S1_AT similar to H3 histone, family 3B cfa
CANINE_2:CFAAFFX.2698.1.S1_S_AT similar to H3 histone, family 3B cfa
CANINE_2:CFAAFFX.357.1.S1_X_AT similar to H3 histone, family 3B cfa
DROSOPHILA_2:1627685_A_AT Histone H3.3A dm
DROSGENOME1:143767_R_AT Histone H3.3A dm
DROSGENOME1:143766_I_AT Histone H3.3A dm
HG-U133B:200080_S_AT H3 histone, family 3A hs
HG-U133A:200080_S_AT H3 histone, family 3A hs
HG-U133A_2:200080_S_AT H3 histone, family 3A hs
PLASMODIUM_ANOPHELES:200080_S_AT H3 histone, family 3A hs
HG-FOCUS:200080_S_AT H3 histone, family 3A hs
U133_X3P:200080_S_AT H3 histone, family 3A hs
HG-U133_PLUS_2:200080_S_AT H3 histone, family 3A hs
HG-U133_PLUS_2:208755_X_AT H3 histone, family 3A hs
HG-U133A_2:208755_X_AT H3 histone, family 3A hs
HG-U133A:208755_X_AT H3 histone, family 3A hs
HG-U133_PLUS_2:211940_X_AT H3 histone, family 3A hs
HG-U133A_2:211940_X_AT H3 histone, family 3A hs
HG-U133A:211940_X_AT H3 histone, family 3A hs
HG-U95AV2:254_AT H3 histone, family 3A hs
HC-G110:254_AT H3 histone, family 3A hs
HUGENEFL:X05855_AT H3 histone, family 3A hs
HUGENEFL:X05855_S_AT H3 histone, family 3A hs
HUGENEFL:M11353_AT H3 histone, family 3A hs
U133_X3P:HS.181307.4.A1_3P_A_AT H3 histone, family 3A hs
HG-U133A_2:213828_X_AT H3 histone, family 3A hs
HG-U133_PLUS_2:213828_X_AT H3 histone, family 3A hs
HG-U133A:213828_X_AT H3 histone, family 3A hs
HG-U133B:200080_S_AT H3 histone, family 3A pseudogene hs
HG-U133A:200080_S_AT H3 histone, family 3A pseudogene hs
HG-U133A_2:200080_S_AT H3 histone, family 3A pseudogene hs
PLASMODIUM_ANOPHELES:200080_S_AT H3 histone, family 3A pseudogene hs
HG-FOCUS:200080_S_AT H3 histone, family 3A pseudogene hs
U133_X3P:200080_S_AT H3 histone, family 3A pseudogene hs
HG-U133_PLUS_2:200080_S_AT H3 histone, family 3A pseudogene hs
HG-U133_PLUS_2:211940_X_AT H3 histone, family 3A pseudogene hs
HG-U133A_2:211940_X_AT H3 histone, family 3A pseudogene hs
HG-U133A:211940_X_AT H3 histone, family 3A pseudogene hs
HUGENEFL:X05855_AT H3 histone, family 3A pseudogene hs
HUGENEFL:X05855_S_AT H3 histone, family 3A pseudogene hs
U133_X3P:HS.181307.4.A1_3P_A_AT H3 histone, family 3A pseudogene hs
HG-U133A_2:213828_X_AT H3 histone, family 3A pseudogene hs
HG-U133_PLUS_2:213828_X_AT H3 histone, family 3A pseudogene hs
HG-U133A:213828_X_AT H3 histone, family 3A pseudogene hs
HG-U95E:73099_AT H3 histone, family 3A pseudogene hs
MOE430A:1423263_AT H3 histone, family 3A mm
MOUSE430A_2:1423263_AT H3 histone, family 3A mm
MOUSE430_2:1423263_AT H3 histone, family 3A mm
MOUSE430_2:1423262_A_AT H3 histone, family 3A mm
MOUSE430A_2:1423262_A_AT H3 histone, family 3A mm
MOE430A:1423262_A_AT H3 histone, family 3A mm
MU11KSUBB:Z85979_F_AT H3 histone, family 3A mm
MG-U74AV2:100380_AT H3 histone, family 3A mm
MOE430A:1434127_A_AT H3 histone, family 3A mm
MOUSE430A_2:1434127_A_AT H3 histone, family 3A mm
MOUSE430_2:1434127_A_AT H3 histone, family 3A mm
YEAST_2:1773019_AT One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6334 nucleosome assembly inferred from electronic annotation QuickGO AmiGO
7001 chromosome organization and biogenesis (sensu Eukaryota) inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
786 nucleosome inferred from electronic annotation QuickGO AmiGO
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98963 Hypothetical protein W05B10.1 [Caenorhabditis elegans] ref|NP_506164.1| W05B10.1 [Caenorhabditis elegans] 3.0E-69
blast CAB11546 Hypothetical protein Y49E10.6 [Caenorhabditis elegans] ref|NP_499608.1| HIStone family member (his-72) [Caenorhabditis elegans] emb|CAE66490.1| Hypothetical protein CBG11770 [Caenorhabditis briggsae] 3.0E-65
blast AAB04902 Histone protein 71 [Caenorhabditis elegans] ref|NP_509344.1| HIStone family member (his-71) [Caenorhabditis elegans] sp|Q10453|H33_CAEEL Histone H3.3 8.0E-65
Protein Domains
Database ID Description E-Value
Pfam IPR007125 EMBL-EBI Histone core 4.9E-27
Sequence
Target Sequence 
>C. ELEGANS:192351_S_AT
caaaccgctcgcaaatcgactggaggaaaagctcccagaaaagctctggcgacgaaggcg
gctcgcaagtcggccattgtcaccggaagtgtcaaaaaagtgcatcgttttcgtccggga
acagtcgctcttcgtgagatcagacgctatcaaaagtctacagagcttctgcttcgcaag
ctaccattccagcgtcttgtccgtgaaatcgcgcaagacttcaaaaccgatctccgtttc
cagtcagctgctatcggagctcttcaggaagcttccgaagcttacctcgttggactcttc
gaagacaccaacctgtgcgccatccacgccaaaagagtcactatcatgccaaagga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAAACCGCTCGCAAATCGACTGGAG 568 191 28 Antisense
GAAAAGCTCTGGCGACGAAGGCGGC 690 353 65 Antisense
GTCGGCCATTGTCACCGGAAGTGTC 500 469 96 Antisense
CATCGTTTTCGTCCGGGAACAGTCG 410 201 130 Antisense
AAGTCTACAGAGCTTCTGCTTCGCA 157 157 181 Antisense
CGTCTTGTCCGTGAAATCGCGCAAG 378 245 220 Antisense
GCAAGACTTCAAAACCGATCTCCGT 668 319 240 Antisense
TCCGTTTCCAGTCAGCTGCTATCGG 247 595 260 Antisense
CTGCTATCGGAGCTCTTCAGGAAGC 363 237 275 Antisense
GAGCTCTTCAGGAAGCTTCCGAAGC 605 387 284 Antisense
AAAGAGTCACTATCATGCCAAAGGA 281 121 359 Antisense
Sequence Source Affymetrix Proprietary Database