[Home] | [Total List]

[192328_at] Eukaryotic protein kinase domain

Description Y42A5A.4 /REP_DB=WormBase Gene ID /WP=CE20258 /TR=Q9U2H1 /GB=CAB63367.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Eukaryotic protein kinase domain
Cluster 6grp_highest_10_10 > 10      6grp_high1_10_10 > 0      4grp_highest_8_8 > 60      4grp_high_8_8 > 26      6grp_highest_nonorm > 90      6grp_total > 04      4grp_total > 38      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 159
1 2 3 4 range
A 226
(3)
P 		144.1
(-1.3)
P 		112.6
(-3)
P 		134.3
(-1.9)
P 		113
B 215.6
(3)
P 		153.2
(0.5)
P 		66.9
(-3)
P 		155.2
(0.6)
P 		149
C 214.4
(3)
P 		119.3
(-1.8)
P 		95.5
(-3)
P 		127
(-1.4)
P 		119
avr 218.7
(3) 		138.9
(-0.8) 		91.7
(-3) 		138.8
(-0.8) 		127

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 147
1 2 3 4 5 6 range
A 205.7
(3)
P 		141.8
(-0.3)
P 		124.1
(-1.2)
P 		163.1
(0.8)
P 		121.2
(-1.3)
P 		89.1
(-3)
P 		117
B 180.7
(3)
P 		155.7
(1.4)
P 		140.5
(0.4)
P 		139.8
(0.4)
P 		114.6
(-1.3)
P 		87.5
(-3)
P 		93
C 219
(3)
P 		175.1
(1.2)
P 		103.1
(-1.7)
P 		192.5
(1.9)
P 		97.9
(-1.9)
P 		71.8
(-3)
P 		147
avr 201.8
(3) 		157.5
(0.8) 		122.6
(-1) 		165.1
(1.1) 		111.2
(-1.6) 		82.8
(-3) 		119
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 67
1 2 3 4 range
A 82.3
(3)
P 		31.3
(-1.9)
P 		29.4
(-2.1)
P 		19.7
(-3)
P 		63
B 68.7
(3)
P 		37.8
(-0.5)
P 		15.5
(-3)
P 		33.1
(-1)
P 		53
C 71
(3)
P 		34.3
(-1.4)
P 		33.3
(-1.6)
P 		21.4
(-3)
P 		50
avr 74
(3) 		34.5
(-1.8) 		26.1
(-2.8) 		24.7
(-3) 		49

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 60
1 2 3 4 5 6 range
A 37.9
(0.4)
P 		50.4
(3)
P 		27
(-1.9)
P 		41.4
(1.1)
P 		36.6
(0.1)
P 		21.7
(-3)
P 		29
B 62.9
(3)
P 		51.8
(0.8)
P 		34.1
(-2.7)
P 		37
(-2.1)
P 		46.6
(-0.2)
P 		32.6
(-3)
P 		30
C 81.2
(3)
P 		53.4
(0.1)
P 		26.3
(-2.8)
P 		38.7
(-1.5)
P 		31.7
(-2.2)
P 		24
(-3)
P 		57
avr 60.7
(3) 		51.9
(1.5) 		29.1
(-2.5) 		39
(-0.8) 		38.3
(-0.9) 		26.1
(-3) 		35
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192328_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14389
Sequence Type Exemplar sequence
Representative Public ID Y42A5A.4 NCBI
Target Description Y42A5A.4 /REP_DB=WormBase Gene ID /WP=CE20258 /TR=Q9U2H1 /GB=CAB63367.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Eukaryotic protein kinase domain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073422(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073422 NCBI Caenorhabditis elegans Y42A5A.4 (Y42A5A.4) mRNA, complete cds. 11/11 None
SNAP00000034856 ENSEMBL cdna:SNAP chromosome:CEL140:V:11108087:11109864:1 11/11 None
GENEFINDER00000034859 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:11105423:11109864:1 11/11 None
Y42A5A.4 ENSEMBL cdna:known chromosome:CEL140:V:11108087:11109864:1 gene:Y42A5A.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:11108086-11109864(+) 100.0 100.0
Public Domain and Genome References
Gene Title Eukaryotic protein kinase domain
Ensembl Y42A5A.4
Entrez Gene 189841 Entrez gene
SwissProt Q9U2H1 EMBL-EBI
WormBase CE20258 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1589471_AT similar to cyclin-dependent kinase-like 1 (CDC2-related kinase) cfa
CANINE_2:CFA.15557.1.A1_AT similar to cyclin-dependent kinase-like 1 (CDC2-related kinase) cfa
CANINE_2:CFAAFFX.22075.1.S1_AT similar to cyclin-dependent kinase-like 1 (CDC2-related kinase) cfa
DROSOPHILA_2:1626477_AT dm
DROSGENOME1:145840_AT dm
CHICKEN:GGAAFFX.7787.1.S1_AT similar to cyclin-dependent kinase-like 1 (CDC2-related kinase) gga
CHICKEN:GGAAFFX.7787.2.S1_AT similar to cyclin-dependent kinase-like 1 (CDC2-related kinase) gga
HG-U133_PLUS_2:207766_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133A:207766_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-FOCUS:207766_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133A_2:207766_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U95AV2:795_S_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HC-G110:795_S_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U95AV2:796_I_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HC-G110:796_I_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HUGENEFL:X66358_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
U133_X3P:G11125775_3P_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
U133_X3P:HS2.405815.2.A1_3P_S_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133_PLUS_2:1555286_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133_PLUS_2:235512_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133B:235512_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HU35KSUBB:RC_T88894_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
U133_X3P:HS.186500.0.A1_3P_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
U133_X3P:HS.131878.0.A1_3P_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133_PLUS_2:244670_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133B:244670_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U95C:50439_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U95C:65666_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U95E:82180_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133_PLUS_2:239859_X_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133B:239859_X_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133_PLUS_2:241928_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U133B:241928_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HG-U95B:45950_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
U133_X3P:HS.280881.0.A1_3P_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
HU35KSUBB:RC_Z38153_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
U133_X3P:HS.22978.1.S1_3P_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
U133_X3P:HS.22978.2.S1_3P_A_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) hs
MU11KSUBB:MSA.26831.0_S_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) mm
MG-U74BV2:163419_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) mm
MOE430B:1429664_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) mm
MOUSE430_2:1429664_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) mm
MOE430B:1453231_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) mm
MOUSE430_2:1453231_AT cyclin-dependent kinase-like 1 (CDC2-related kinase) mm
RG-U34B:RC_AI029024_AT Cyclin-dependent kinase-like 1 (CDC2-related kinase) (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB63367 Hypothetical protein Y42A5A.4 [Caenorhabditis elegans] ref|NP_505823.1| Y42A5A.4 [Caenorhabditis elegans] 0.0
blast CAE75148 Hypothetical protein CBG23082 [Caenorhabditis briggsae] 0.0
blast NP_004187 cyclin-dependent kinase-like 1 [Homo sapiens] sp|Q00532|KKIA_HUMAN Serine/threonine-protein kinase KKIALRE (Cyclin-dependent kinase-like 1) 1.0E-114
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-74
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-76
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 8.0E-76
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 2.0E-77
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-95
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-95
Sequence
Target Sequence 
>C. ELEGANS:192328_AT
gtggcaactcgttggtaccgtagtccagaacttctggtcggtgatgttcaatatgggcca
cctgtagacatttgggctgtaggatgtgtatatgcggagctgttgactggcgaagctcta
tggccgggaagaagtgatatcgatcagttatatcatattcgaaaaactttaggggaattt
ttacctcgtcatatttcaattttccgcacaaatcaatttttctttggactttcaattcct
gaaccggagcatcttgaacctctaccctctaagctcccaaatgcgagcagtgcacagctc
gattttctacagaagtgcttcgaaatgtctccagatcgacgcttctcatgtagtgagctt
atgctgcatggaatcttttcgaattggatattacggatacgacaggatgagagtacacca
actgggctcacttcaaaaagaagccccaactacctaccacttctgaatgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGGCAACTCGTTGGTACCGTAGTC 544 489 493 Antisense
GGGCCACCTGTAGACATTTGGGCTG 687 429 547 Antisense
TATGCGGAGCTGTTGACTGGCGAAG 623 655 583 Antisense
ACTGGCGAAGCTCTATGGCCGGGAA 290 89 598 Antisense
ACCTCGTCATATTTCAATTTTCCGC 18 89 675 Antisense
GGACTTTCAATTCCTGAACCGGAGC 614 523 718 Antisense
GAACCGGAGCATCTTGAACCTCTAC 276 345 733 Antisense
GCAGTGCACAGCTCGATTTTCTACA 387 311 779 Antisense
GAAATGTCTCCAGATCGACGCTTCT 271 361 814 Antisense
TGAGAGTACACCAACTGGGCTCACT 71 569 900 Antisense
CCAACTACCTACCACTTCTGAATGG 78 275 938 Antisense
Sequence Source Affymetrix Proprietary Database