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[192318_at] zinc metallopeptidase (M1 family)

Description R03G8.4 /REP_DB=WormBase Gene ID /WP=CE18904 /TR=Q21673 /GB=CAA93681.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=zinc metallopeptidase (M1 family)
Cluster 6grp_total > 70      4grp_total > 37      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 24
1 2 3 4 range
A 1.7
(-2.8)
A 		1.3
(-3)
A 		1.5
(-2.9)
A 		11.7
(3)
A 		10
B 24.1
(3)
A 		4.4
(-2.1)
A 		0.8
(-3)
A 		1.6
(-2.8)
A 		23
C 0.9
(-2.8)
A 		11.7
(3)
A 		0.6
(-3)
A 		2.9
(-1.8)
A 		11
avr 8.9
(3) 		5.8
(0.6) 		1
(-3) 		5.4
(0.3) 		8

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 33
1 2 3 4 5 6 range
A 3.9
(-2)
A 		4.6
(-1.7)
A 		20.4
(3)
A 		0.4
(-3)
A 		1.8
(-2.6)
A 		0.9
(-2.9)
A 		20
B 0.6
(-3)
A 		2.9
(-2.6)
A 		3.4
(-2.5)
A 		33.2
(3)
A 		4.1
(-2.4)
A 		1.2
(-2.9)
A 		33
C 2.4
(-2.3)
A 		1.1
(-2.8)
A 		1.5
(-2.7)
A 		14.6
(3)
A 		0.7
(-3)
A 		1.3
(-2.7)
A 		14
avr 2.3
(-2.5) 		2.9
(-2.3) 		8.4
(-0.1) 		16.1
(3) 		2.2
(-2.6) 		1.1
(-3) 		15
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 8
1 2 3 4 range
A 0.6
(-1.7)
A 		0.3
(-3)
A 		0.4
(-2.6)
A 		1.7
(3)
A 		1
B 7.7
(3)
A 		1.1
(-2.3)
A 		0.2
(-3)
A 		0.3
(-2.9)
A 		8
C 0.3
(-2.8)
A 		3.4
(3)
A 		0.2
(-3)
A 		0.5
(-2.4)
A 		3
avr 2.9
(3) 		1.6
(0) 		0.3
(-3) 		0.8
(-1.8) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 9
1 2 3 4 5 6 range
A 0.7
(-2.2)
A 		1.6
(-0.9)
A 		4.4
(3)
A 		0.1
(-3)
A 		0.5
(-2.4)
A 		0.2
(-2.9)
A 		4
B 0.2
(-3)
A 		1
(-2.4)
A 		0.8
(-2.6)
A 		8.8
(3)
A 		1.7
(-2)
A 		0.5
(-2.8)
A 		9
C 0.9
(-1.4)
A 		0.3
(-2.8)
A 		0.4
(-2.6)
A 		2.9
(3)
A 		0.2
(-3)
A 		0.4
(-2.6)
A 		3
avr 0.6
(-2.7) 		1
(-2) 		1.9
(-0.4) 		3.9
(3) 		0.8
(-2.3) 		0.4
(-3) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192318_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17318
Sequence Type Exemplar sequence
Representative Public ID R03G8.4 NCBI
Target Description R03G8.4 /REP_DB=WormBase Gene ID /WP=CE18904 /TR=Q21673 /GB=CAA93681.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=zinc metallopeptidase (M1 family)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077775(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077775 NCBI Caenorhabditis elegans R03G8.4 (R03G8.4) mRNA, complete cds. 11/11 None
GENEFINDER00000031820 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:13094556:13104866:-1 11/11 None
R03G8.4 ENSEMBL cdna:known chromosome:CEL140:X:13101226:13104125:-1 gene:R03G8.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000031815 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:13101225-13104125(-) 100.0 100.0
Public Domain and Genome References
Gene Title zinc metallopeptidase (M1 family)
Ensembl R03G8.4
Entrez Gene 187546 Entrez gene
SwissProt Q21673 EMBL-EBI
WormBase CE18904 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4179 membrane alanyl aminopeptidase activity inferred from electronic annotation QuickGO AmiGO
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93681 Hypothetical protein R03G8.4 [Caenorhabditis elegans] ref|NP_510176.1| R03G8.4 [Caenorhabditis elegans] 0.0
blast CAA93680 Hypothetical protein R03G8.6 [Caenorhabditis elegans] ref|NP_510175.1| R03G8.6 [Caenorhabditis elegans] 0.0
blast CAA93680 Hypothetical protein R03G8.6 [Caenorhabditis elegans] ref|NP_510175.1| R03G8.6 [Caenorhabditis elegans] 1.0E-179
blast CAE64729 Hypothetical protein CBG09516 [Caenorhabditis briggsae] 1.0E-156
blast CAE64729 Hypothetical protein CBG09516 [Caenorhabditis briggsae] 1.0E-151
Protein Domains
Database ID Description E-Value
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 1.0E-126
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 1.0E-126
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192318_AT
tattctgcaagtacaaaggctcgtgtactaagtgatgctattcattattactacaagggt
gaagtttcactgaagaactctctcattattgcgcaagccttggcaaatgatacaaatcaa
gaaattcgcagtaaggctgcaatgcatcttacgcatgcgattgcgaaattgaatcaggat
attaatgaagcatcaagaatattggaaggaatacagattgaagaggtaaatgatatcgat
atattttcgaaatgtggtccttttaaagaatttccaaaatgcttctttaatgcattcaac
agctatgatcatttttgtgcttctatgaaacttgatttgagtaaaagttcaattgatcaa
attgtttggtggctgaaatttgatcaatacaaatcgatgctcatttcaatgttacattgc
ctaaatgaggattcaatgcaaaaagttcttcatgaatttgttgatgtatcagaaacccca
ggtccagaaaatcctcaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TATTCTGCAAGTACAAAGGCTCGTG 332 663 1771 Antisense
AAGGCTCGTGTACTAAGTGATGCTA 593 161 1786 Antisense
GATGCTATTCATTATTACTACAAGG 534 413 1804 Antisense
GAAGTTTCACTGAAGAACTCTCTCA 182 337 1831 Antisense
AACTCTCTCATTATTGCGCAAGCCT 559 141 1846 Antisense
GGCTGCAATGCATCTTACGCATGCG 630 537 1905 Antisense
GAATTTCCAAAATGCTTCTTTAATG 424 309 2038 Antisense
GCTATGATCATTTTTGTGCTTCTAT 568 303 2072 Antisense
ATACAAATCGATGCTCATTTCAATG 392 23 2157 Antisense
TGATGTATCAGAAACCCCAGGTCCA 383 567 2232 Antisense
ACCCCAGGTCCAGAAAATCCTCACA 26 21 2245 Antisense
Sequence Source Affymetrix Proprietary Database