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[192272_at] zinc finger protein

Description K11G9.4 /REP_DB=WormBase Gene ID /WP=CE07377 /GEN=egl-46 /TR=Q23011 /GB=AAB04977.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=zinc finger protein
Cluster 6grp_total > 36      4grp_total > 44      6grp_cgc > 15      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 116
1 2 3 4 range
A 141.6
(-0.5)
A 		205.2
(3)
A 		124.1
(-1.5)
A 		95.9
(-3)
A 		109
B 179.5
(3)
P 		168.9
(2.2)
A 		98.3
(-3)
A 		107.6
(-2.3)
A 		81
C 173.9
(1)
A 		211.5
(3)
P 		99.3
(-3)
A 		121.6
(-1.8)
A 		112
avr 165
(0.9) 		195.2
(3) 		107.2
(-3) 		108.4
(-2.9) 		88

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 133
1 2 3 4 5 6 range
A 218.5
(3)
P 		189.3
(1.6)
P 		106.8
(-2.2)
A 		89.4
(-3)
A 		104.4
(-2.3)
A 		155.1
(0.1)
P 		129
B 181
(0.8)
P 		222.1
(3)
P 		123.6
(-2.4)
A 		152.3
(-0.8)
A 		111.9
(-3)
A 		174.2
(0.4)
P 		110
C 191.5
(2.4)
P 		199.8
(3)
P 		161.4
(0.2)
A 		150
(-0.6)
A 		116.8
(-3)
A 		184.7
(1.9)
P 		83
avr 197
(2.6) 		203.7
(3) 		130.6
(-1.7) 		130.6
(-1.7) 		111
(-3) 		171.3
(0.9) 		93
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 47
1 2 3 4 range
A 51.6
(3)
A 		44.5
(1.9)
A 		32.5
(-0)
A 		14
(-3)
A 		38
B 57.2
(3)
P 		41.7
(0.3)
A 		22.8
(-3)
A 		22.9
(-3)
A 		34
C 57.6
(2.5)
A 		60.8
(3)
P 		34.6
(-0.9)
A 		20.5
(-3)
A 		40
avr 55.5
(3) 		49
(1.9) 		30
(-1.2) 		19.1
(-3) 		36

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 51
1 2 3 4 5 6 range
A 40.3
(-0.6)
P 		67.3
(3)
P 		23.3
(-2.9)
A 		22.7
(-3)
A 		31.5
(-1.8)
A 		37.8
(-1)
P 		45
B 63
(1.5)
P 		73.9
(3)
P 		30
(-3)
A 		40.3
(-1.6)
A 		45.5
(-0.9)
A 		65
(1.8)
P 		44
C 71
(3)
P 		61
(1.5)
P 		41.1
(-1.4)
A 		30.2
(-3)
A 		37.8
(-1.9)
A 		61.8
(1.6)
P 		41
avr 58.1
(1.5) 		67.4
(3) 		31.5
(-2.9) 		31.1
(-3) 		38.3
(-1.8) 		54.9
(0.9) 		36
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192272_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11786
Sequence Type Exemplar sequence
Representative Public ID K11G9.4 NCBI
Target Description K11G9.4 /REP_DB=WormBase Gene ID /WP=CE07377 /GEN=egl-46 /TR=Q23011 /GB=AAB04977.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=zinc finger protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072293(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072293 NCBI Caenorhabditis elegans EGg Laying defective family member (egl-46) (egl-46) mRNA, complete cds. 11/11 None
SNAP00000025345 ENSEMBL cdna:SNAP chromosome:CEL140:V:6682251:6684161:-1 11/11 None
GENEFINDER00000025351 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:6682251:6684152:-1 11/11 None
K11G9.4 ENSEMBL cdna:known chromosome:CEL140:V:6681741:6684169:-1 gene:K11G9.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6682251-6684162(-) 100.0 100.0
Public Domain and Genome References
Gene Title zinc finger protein
Gene Symbol egl-46
Ensembl K11G9.4
Entrez Gene 179058 Entrez gene
SwissProt Q23011 EMBL-EBI
WormBase CE07377 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1634039_AT nervous fingers 1 dm
DROSGENOME1:151651_AT nervous fingers 1 dm
DROSGENOME1:142626_AT nervous fingers 1 dm
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB04977 Egg laying defective protein 46 [Caenorhabditis elegans] ref|NP_504694.1| EGg Laying defective family member (egl-46) [Caenorhabditis elegans] gb|AAG13398.1| C2H2 zinc finger protein EGL-46 [Caenorhabditis elegans] 1.0E-151
blast AAB04977 Egg laying defective protein 46 [Caenorhabditis elegans] ref|NP_504694.1| EGg Laying defective family member (egl-46) [Caenorhabditis elegans] gb|AAG13398.1| C2H2 zinc finger protein EGL-46 [Caenorhabditis elegans] 1.0E-149
blast CAE71930 Hypothetical protein CBG18993 [Caenorhabditis briggsae] 1.0E-120
blast CAE71930 Hypothetical protein CBG18993 [Caenorhabditis briggsae] 1.0E-118
blast AAF54491 CG12809-PA [Drosophila melanogaster] ref|NP_524300.1| CG12809-PA [Drosophila melanogaster] 3.0E-33
Protein Domains
Database ID Description E-Value
Pfam IPR007087 EMBL-EBI Zn-finger, C2H2 type 1.4E-5
Pfam IPR007087 EMBL-EBI Zn-finger, C2H2 type 1.4E-5
Sequence
Target Sequence 
>C. ELEGANS:192272_AT
aatctcgaaaacgtcctctaccgatagacccgaaaaagacaaagcttcgaaaactgaatg
aagacactgtgaccagttctccagtcagcggtatgttcataaaggaggaggcggatgtga
aatctgtggaggagctccaaaaagaagctgatttgctcgatgagacagcagcatatgtag
aggtcaccgaggagtcaagacaaaagattgacgagattccaaatgtcattggagactgta
tctgccggctgtgcaaggtgaaatacgaggacgtgttcaagctggcacaacacaaatgtc
caagaattgctcacgaggaatacaaatgtccggattgtgacaaggtgttctcatgtccgg
ccaatttggcatcacatcgtcgttggcacaaaccccgtaatgagctcggtggctctccac
ccgcacaatcctcaacaattgtctcctgctccacctgcttcaactcatttccaacaaaga
agatgctcaagctgcactcgtcgacgtgtcaaagatcgcctctt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATCTCGAAAACGTCCTCTACCGAT 446 167 314 Antisense
GAAGACACTGTGACCAGTTCTCCAG 131 341 373 Antisense
CAGTTCTCCAGTCAGCGGTATGTTC 49 205 387 Antisense
GTCATTGGAGACTGTATCTGCCGGC 136 469 538 Antisense
GTATCTGCCGGCTGTGCAAGGTGAA 287 455 551 Antisense
TGACAAGGTGTTCTCATGTCCGGCC 141 573 651 Antisense
TTGGCATCACATCGTCGTTGGCACA 275 709 679 Antisense
TTGGCACAAACCCCGTAATGAGCTC 443 709 696 Antisense
CGTAATGAGCTCGGTGGCTCTCCAC 245 247 709 Antisense
AGAAGATGCTCAAGCTGCACTCGTC 107 75 791 Antisense
GTCGACGTGTCAAAGATCGCCTCTT 224 475 813 Antisense
Sequence Source Affymetrix Proprietary Database